Masahiko Okamoto

Summary

Affiliation: Kyoto Prefectural University of Medicine
Country: Japan

Publications

  1. ncbi request reprint Management and outcome of living kidney grafts with multiple arteries
    Yayoi Kadotani
    Department of Transplantation and Regenerative Surgery, Graduate School of Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, 602 8566, Japan
    Surg Today 35:459-66. 2005
  2. doi request reprint Histopathologic evaluation of living kidney donor candidates by pre-operative kidney biopsy
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 23:58-61. 2009
  3. doi request reprint A case of recurrent focal segmental glomerulosclerosis (FSGS) involving massive proteinuria (>50 g/day) immediately after renal transplantation
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
    Clin Transplant 25:53-8. 2011
  4. doi request reprint Analysis of preexisting baseline kidney lesions revealed by biopsy in living kidney donors: relationship with clinical parameters at the time of donation
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Clin Transplant 24:27-30. 2010
  5. ncbi request reprint Ten-year protocol biopsy findings of renal allografts in the calcineurin inhibitor era
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 20:16-9. 2006
  6. ncbi request reprint Clinicopathological evaluation of renal allografts of four patients by 20-year protocol biopsies
    Masahiko Okamoto
    Department of Transplantation and Endocrine Surgery, Kyoto Prefectural University of Medicine, Kyoto 602, Japan
    Clin Transplant 17:20-4. 2003
  7. ncbi request reprint Clinicopathological evaluation of renal allograft treated with anti-CD25 monoclonal antibody
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 19:49-53. 2005
  8. ncbi request reprint The consequences for live kidney donors with preexisting glucose intolerance without diabetic complication: analysis at a single Japanese center
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    Transplantation 89:1391-5. 2010
  9. ncbi request reprint Therapeutic drug monitoring of mycophenolic acid in renal transplant recipients
    M Okamoto
    Department of Transplantation and Regenerative Surgery, Graduate School of Medical Science, Kyoto, Japan
    Transplant Proc 37:859-60. 2005
  10. doi request reprint Short- and long-term donor outcomes after kidney donation: analysis of 601 cases over a 35-year period at Japanese single center
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Transplantation 87:419-23. 2009

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Management and outcome of living kidney grafts with multiple arteries
    Yayoi Kadotani
    Department of Transplantation and Regenerative Surgery, Graduate School of Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, 602 8566, Japan
    Surg Today 35:459-66. 2005
    ..To determine if MRA grafts affect the short- and long-term outcomes of grafts and patients, we analyzed 340 grafts procured by open nephrectomy...
  2. doi request reprint Histopathologic evaluation of living kidney donor candidates by pre-operative kidney biopsy
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 23:58-61. 2009
    ..Longer-term studies will be needed to clarify the outcome in both the donors and recipients in these cases...
  3. doi request reprint A case of recurrent focal segmental glomerulosclerosis (FSGS) involving massive proteinuria (>50 g/day) immediately after renal transplantation
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
    Clin Transplant 25:53-8. 2011
    ..The patient's clinical course was compatible with FSGS recurrence. Although the early pathological changes were not typical of FSGS, they might be indicative of the primary lesion that subsequently progresses to typical FSGS...
  4. doi request reprint Analysis of preexisting baseline kidney lesions revealed by biopsy in living kidney donors: relationship with clinical parameters at the time of donation
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Clin Transplant 24:27-30. 2010
    ..A follow-up study will be required to determine whether these mild histological findings at the time of donation influence long-term outcome in the donor...
  5. ncbi request reprint Ten-year protocol biopsy findings of renal allografts in the calcineurin inhibitor era
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 20:16-9. 2006
    ..Longer follow-up studies are needed to confirm whether CNI should be continued or not in the long-term period following kidney transplantation for better graft survival...
  6. ncbi request reprint Clinicopathological evaluation of renal allografts of four patients by 20-year protocol biopsies
    Masahiko Okamoto
    Department of Transplantation and Endocrine Surgery, Kyoto Prefectural University of Medicine, Kyoto 602, Japan
    Clin Transplant 17:20-4. 2003
    ..We conclude that the protocol biopsies even at 20 years can contribute to predict the fate of renal allografts...
  7. ncbi request reprint Clinicopathological evaluation of renal allograft treated with anti-CD25 monoclonal antibody
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 19:49-53. 2005
    ..The careful inspection is necessary to find out the occurrences of acute rejection more than 2 months after transplantation because immunological situation has been changing around this period...
  8. ncbi request reprint The consequences for live kidney donors with preexisting glucose intolerance without diabetic complication: analysis at a single Japanese center
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    Transplantation 89:1391-5. 2010
    ..To assess the indications for live kidney donation in glucose intolerance (GI), we analyzed perioperative complications associated with donor nephrectomies performed at our institution and followed up the long-term consequences...
  9. ncbi request reprint Therapeutic drug monitoring of mycophenolic acid in renal transplant recipients
    M Okamoto
    Department of Transplantation and Regenerative Surgery, Graduate School of Medical Science, Kyoto, Japan
    Transplant Proc 37:859-60. 2005
    ..The possible target level of MPA AUC0-9 would be approximately 30 ng.hr/mL using the present immunosuppressive regimen...
  10. doi request reprint Short- and long-term donor outcomes after kidney donation: analysis of 601 cases over a 35-year period at Japanese single center
    Masahiko Okamoto
    Department of Organ Interaction Research Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Transplantation 87:419-23. 2009
    ..The lack of deceased donors in Japan means that living-donor kidney transplantation is necessary in as many as 80% of cases. However, there are few data on perioperative complications and long-term outcome for live kidney donors...
  11. doi request reprint The beneficial effect of high-dose mizoribine combined with cyclosporine, basiliximab, and corticosteroids on CMV infection in renal transplant recipients
    Norio Yoshimura
    Department of Organ Transplantation and General Surgery, Kyoto Prefectural University of Medicine, 465 Hirokoji, Kawaramachi, Kamikyo ku, Kyoto 602 8566, Japan
    Clin Exp Nephrol 17:127-33. 2013
    ..Therefore, we investigated whether high-dose MZR, at 6 mg/kg/day, would be effective and safe for kidney transplant patients in conjunction with cyclosporine (CsA), basiliximab, and corticosteroids...
  12. doi request reprint Degree of corticosteroid treatment within the first 2 months of renal transplantation has a strong influence on the incidence of osteonecrosis of the femoral head
    Masahiko Shibatani
    Department of Orthopedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Acta Orthop 79:631-6. 2008
    ..It has been suggested that avascular osteonecrosis (AVN) of the femoral head develops early after renal transplantation. We evaluated the relationship between risk of AVN and dose of steroids administered in different time periods...
  13. ncbi request reprint Tissue factor antisense oligonucleotides prevent renal ischemia-reperfusion injury
    Masahide Matsuyama
    Department of Organ Transplant and Endocrine Surgery, Kyoto Prefectural University of Medicine, Kawaramachi, Kamigyouku, Kyoto, Japan
    Transplantation 76:786-91. 2003
    ..We designed an antisense (AS) phosphorothioate oligodeoxynucleotide (ODN) to specifically inhibit the expression of rat TF to study the effects of the AS ODN on renal ischemia-reperfusion injury in the rat...
  14. ncbi request reprint ApoB C7623T polymorphism predicts risk for steroid-induced osteonecrosis of the femoral head after renal transplantation
    Tetsurou Hirata
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii chou, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    J Orthop Sci 12:199-206. 2007
    ....
  15. doi request reprint Current status of organ transplantation in Japan and worldwide
    Norio Yoshimura
    Department of Organ Transplant and Regenerative Surgery, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Hirokoji Kawaramachi, Kamigyo ku, Kyoto, 602 0841, Japan
    Surg Today 40:514-25. 2010
    ..Eight recipients survived and stopped parenteral nutrition with full-functioning grafts. Amendment of the Japanese law for the utilization of deceased donors should increase the number available donors in the future...
  16. doi request reprint Findings of graft biopsy specimens within 90 days after ABO blood group incompatible living donor kidney transplantation compared with ABO-identical and non-identical transplantation
    Hidetaka Ushigome
    Department of Transplantation and Regenerative Surgery, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan
    Clin Transplant 24:16-21. 2010
    ..AMR was difficult to be diagnosed by C4d analysis in ABO-incompatible transplant cases. Glomerular injury score, g score, may be considered as more significant and the injury should be cured thoroughly...
  17. ncbi request reprint Clinical pharmacokinetics of mycophenolate mofetil in Japanese renal transplant recipients: A retrospective cohort study in a single center
    Nobuyuki Sugioka
    Department of Pharmacokinetics, Kyoto Pharmaceutical University, Kyoto, Japan
    Biol Pharm Bull 29:2099-105. 2006
    ..However, though not frequently, AUC obtained by multiple blood sampling after MMF dosing was needed. In addition, EHRA has led to increasing interest in MMF medication...
  18. ncbi request reprint Relationship between postrenal transplant osteonecrosis of the femoral head and gene polymorphisms related to the coagulation and fibrinolytic systems in Japanese subjects
    Takeshi Asano
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Transplantation 77:220-5. 2004
    ....
  19. ncbi request reprint Low molecular weight phenotype of Apo(a) is a risk factor of corticosteroid-induced osteonecrosis of the femoral head after renal transplant
    Tetsurou Hirata
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Rheumatol 34:516-22. 2007
    ..We examined the relationships between development of ONF and genetic variations and plasma level of lipoprotein(a) (Lp(a)), which is closely involved in the coagulation and fibrinolytic systems and lipid metabolism...
  20. doi request reprint A case of living-related renal transplant from the donor with membranous nephropathy
    Kiyokazu Akioka
    Department of Transplantation and Regenerative Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Clin Transplant 23:62-6. 2009
    ..Marginally appropriate donors might be considered for renal graft because of the shortage of donors. A successful outcome after kidney transplantation from a living-related donor diagnosed as membranous nephropathy is reported...
  21. ncbi request reprint Antisense oligonucleotide for tissue factor inhibits hepatic ischemic reperfusion injury
    Kenji Nakamura
    Department of Organ Transplant and Endocrine Surgery, Research Institute for Neurological Diseases and Geriatrics, Kyoto Prefectural University of Medicine, 465 Hirokoji, Kawaramachi, Kamigyo ku, Kyoto City, Kyoto 602 8566, Japan
    Biochem Biophys Res Commun 297:433-41. 2002
    ..These results suggest that AS-1/TF can strongly suppress the expression of TF and thereby inhibit ischemic reperfusion injury to the rat liver...
  22. doi request reprint Overlapped glomerular lesions of chronic rejection and recurrent lupus nephritis in transplanted kidney: a case report
    Naoko Masuzawa
    Department of Surgical Pathology, Graduate School of Medical Science, Kamigyo ku, Kyoto, Japan
    Clin Transplant 25:49-52. 2011
    ..Complete morphologic studies with both immunofluorescence and electron microscopic evaluations in addition to microscopic examination should be performed to elucidate complex histological findings...
  23. ncbi request reprint Expression of cyclooxygenase-1 and -2 in human breast cancer
    Norio Yoshimura
    Department of Organ Transplant and Endocrinological Surgery, Kyoto Prefectural University of Medicine, 465 Hirokoji, Kawaramachi, Kamigyo ku, 602 0841 Kyoto, Japan
    Surg Today 33:805-11. 2003
    ..We investigated the expression of cyclooxygenase (Cox-1 and Cox-2) in mammary tissues from patients with breast cancer...
  24. doi request reprint Efficacy of tonsillectomy for patients with recurrence of IgA nephropathy after kidney transplantation
    Hidetaka Ushigome
    Department of Transplantation and Regenerative Surgery, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan
    Clin Transplant 23:17-22. 2009
    ..Tonsillectomy had possibility to be a favorable treatment of hematuria or proteinuria in recurrent IgAN recipients...
  25. ncbi request reprint Pulmonary embolism in a living-related kidney transplantation donor
    Hidetaka Ushigome
    Department of Organ Transplant and Endoclinological Surgery, Kyoto Prefectural University of Medicine, 465 Hirokoji, Kawaramachi, Kamikyo ku, Kyoto 602 8566, Japan
    Surg Today 33:399-402. 2003
    ..It is very important for surgeons to realize that serious complications such as PE can develop in any case of living donor nephrectomy...
  26. doi request reprint BK virus-associated nephropathy in a kidney transplant recipient successfully treated with cidofovir, the first case in Japan
    Kiyokazu Akioka
    Department of Transplantation and Regenerative Surgery, Graduate School of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Int J Urol 15:369-71. 2008
    ..BK virus DNA in the blood decreased under the threshold level. sCr was stable and remained about 2.2 mg/dl for three months after the final treatment of cidofovir...
  27. ncbi request reprint Effect of plasma lipid on pharmacokinetics of ciclosporin and its relationship with plasma prednisolone level in renal transplant patients
    Nobuyuki Sugioka
    Department of Pharmacokinetics, Kyoto Pharmaceutical University, Yamashina ku, and Department of Hospital Pharmacy, Kyoto Prefectural University of Medicine, Kamigyou ku Kyoto 602 8566, Japan
    J Pharm Pharmacol 58:1193-200. 2006
    ..These results suggested that monitoring of the biochemical parameters of the plasma lipid and plasma PSL level might be useful for the TDM of CyA...
  28. ncbi request reprint [Indication and current issues in liver transplantation for hepatocellular carcinoma]
    Satoshi Kaihara
    Department of Transplantation and Regenerative Surgery, Kyoto Prefectural University of Medicine
    Nihon Shokakibyo Gakkai Zasshi 101:264-8. 2004
  29. ncbi request reprint The role of tissue factor in renal ischemic reperfusion injury of the rat
    Hidetaka Ushigome
    Department of Organ Transplant and Endocrinological Surgery, Kyoto Prefectural University of Medicine, Kyoto 602, Japan
    J Surg Res 102:102-9. 2002
    ..We studied the role of TF in the kidney following warm ischemic reperfusion and studied the effect of TFPI in vivo...
  30. ncbi request reprint ABCB1 C3435T and G2677T/A polymorphism decreased the risk for steroid-induced osteonecrosis of the femoral head after kidney transplantation
    Takeshi Asano
    Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    Pharmacogenetics 13:675-82. 2003
    ..An assessment of C3435T and G2677T/A polymorphisms preceding steroid treatment could be useful for predicting the resistance to ONF development...
  31. ncbi request reprint Endoscopic resection for the diagnosis of visceral Kaposi's sarcoma
    Junichi Sakagami
    Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajiicho Hirokoji Kamigyoku, Kyoto 602 8566, Japan
    J Gastroenterol 40:98-103. 2005
    ..This is the first report of a patient with visceral Kaposi's sarcoma who underwent endoscopic resection that reliably confirmed histological diagnosis and the viral genome at the same time...
  32. ncbi request reprint [The present status and future of organ transplantation]
    Norio Yoshimura
    Department of Organ Transplant and Endocrine Surgery, Kyoto Prefectural University of Medicine
    Nihon Rinsho Meneki Gakkai Kaishi 25:156-69. 2002
  33. ncbi request reprint Successful treatment of invasive pulmonary aspergillosis after ABO-incompatible living donor liver transplantation under rapid steroid withdrawal protocol
    Satoshi Kaihara
    Transplantation 83:1408-9. 2007