T Nakahata

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. pmc Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis
    Itaru Kato
    Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan
    PLoS ONE 6:e27042. 2011
  2. pmc A long-term follow-up of a girl with dilated cardiomyopathy after mitral valve replacement and septal anterior ventricular exclusion
    Shiro Baba
    Department of Pediatrics, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    J Cardiothorac Surg 4:53. 2009
  3. ncbi request reprint Ex vivo expansion of human hematopoietic stem cells
    T Nakahata
    Department of Pediatrics, Graduate School of Medicine, Kyoto University, Japan
    Int J Hematol 73:6-13. 2001
  4. ncbi request reprint Living-donor liver transplantation for propionic acidaemia
    T Yorifuji
    Department of Pediatrics, Kyoto University Hospital, 54 Shogoin Sakyo, Kyoto 606 8507, Japan
    J Inherit Metab Dis 27:205-10. 2004
  5. pmc A method to identify cDNAs based on localization of green fluorescent protein fusion products
    K Misawa
    Departments of Hematopoietic Factors, Clinical Oncology, and Hematology Oncology, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    Proc Natl Acad Sci U S A 97:3062-6. 2000
  6. ncbi request reprint Molecular and clinical analysis of Japanese patients with 3-hydroxy-3-methylglutaryl CoA lyase (HL) deficiency
    J Muroi
    Department of Pediatrics, Kyoto University Hospital, Japan
    Hum Genet 107:320-6. 2000
  7. ncbi request reprint Successful hematopoietic stem cell transplantation for aplastic anemia following living-related liver transplantation
    K Umeda
    Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Bone Marrow Transplant 30:531-4. 2002
  8. ncbi request reprint Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors
    H Hisakawa
    Department of Clinical Oncology, Division of DNA Biology and Embryo Engineering, Center for Experimental Medicine, The Institute of Medical Science, The University of Tokyo, Japan
    Blood 98:3618-25. 2001
  9. ncbi request reprint Intracranial aneurysms in Ehlers-Danlos syndrome type IV in early childhood
    T Kato
    Department of Pediatrics, Faculty of Medicine, Kyoto University, Kyoto, Japan
    Pediatr Neurol 25:336-9. 2001
  10. ncbi request reprint Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides
    Y Yamanaka
    Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
    Biochem Biophys Res Commun 287:198-203. 2001

Collaborators

Detail Information

Publications14

  1. pmc Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis
    Itaru Kato
    Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan
    PLoS ONE 6:e27042. 2011
    ..Our findings form the basis for therapeutic approaches that target the extramedullary niche by inhibiting the SDF-1/CXCR4 axis...
  2. pmc A long-term follow-up of a girl with dilated cardiomyopathy after mitral valve replacement and septal anterior ventricular exclusion
    Shiro Baba
    Department of Pediatrics, Graduate School of Medicine, Kyoto University, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    J Cardiothorac Surg 4:53. 2009
    ..0% of normal) to 62.5 mm (144.2% of normal) and 7.6% to 18.3% respectively. Furthermore, her serum BNP decreased from 2217.5 pg/ml to 112.0 pg/ml. Her cardiac function has remained stable for 7 years since the procedures were performed...
  3. ncbi request reprint Ex vivo expansion of human hematopoietic stem cells
    T Nakahata
    Department of Pediatrics, Graduate School of Medicine, Kyoto University, Japan
    Int J Hematol 73:6-13. 2001
    ..The culture method with the IL-6/sIL-6R complex and other cytokines may pave the way for ex vivo expansion of human transplantable HSCs suitable for clinical applications...
  4. ncbi request reprint Living-donor liver transplantation for propionic acidaemia
    T Yorifuji
    Department of Pediatrics, Kyoto University Hospital, 54 Shogoin Sakyo, Kyoto 606 8507, Japan
    J Inherit Metab Dis 27:205-10. 2004
    ..Adequate protein restriction and medication need to be maintained even after successful transplantation...
  5. pmc A method to identify cDNAs based on localization of green fluorescent protein fusion products
    K Misawa
    Departments of Hematopoietic Factors, Clinical Oncology, and Hematology Oncology, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    Proc Natl Acad Sci U S A 97:3062-6. 2000
    ..Using FL-REX, we have identified 25 cDNAs, most of which showed reasonable subcellular localization as GFP-fusion proteins, indicating that FL-REX is useful for identification of proteins that show specific intracellular localization...
  6. ncbi request reprint Molecular and clinical analysis of Japanese patients with 3-hydroxy-3-methylglutaryl CoA lyase (HL) deficiency
    J Muroi
    Department of Pediatrics, Kyoto University Hospital, Japan
    Hum Genet 107:320-6. 2000
    ..In general, patients with null-activity mutations presented earlier in life, whereas those with residual activities presented later...
  7. ncbi request reprint Successful hematopoietic stem cell transplantation for aplastic anemia following living-related liver transplantation
    K Umeda
    Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Bone Marrow Transplant 30:531-4. 2002
    ..Conditioning consisted of cyclophosphamide (CY) 200 mg/kg and 7 Gy total lymphoid irradiation (TLI). Marrow engraftment was prompt and there was no significant graft-versus-host disease (GVHD)...
  8. ncbi request reprint Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors
    H Hisakawa
    Department of Clinical Oncology, Division of DNA Biology and Embryo Engineering, Center for Experimental Medicine, The Institute of Medical Science, The University of Tokyo, Japan
    Blood 98:3618-25. 2001
    ....
  9. ncbi request reprint Intracranial aneurysms in Ehlers-Danlos syndrome type IV in early childhood
    T Kato
    Department of Pediatrics, Faculty of Medicine, Kyoto University, Kyoto, Japan
    Pediatr Neurol 25:336-9. 2001
    ..Ehlers-Danlos syndrome type IV should be considered in the differential diagnosis of cerebrovascular disorder and stroke in early childhood...
  10. ncbi request reprint Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides
    Y Yamanaka
    Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
    Biochem Biophys Res Commun 287:198-203. 2001
    ..The products of these four genes may be candidates for mediating the ability of 14-membered macrolides to suppress chronic inflammation...
  11. ncbi request reprint Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15
    S Sasaki
    Department of Pediatrics, School of Medicine, Hirosaki University, Japan
    Oncogene 19:3739-49. 2000
    ..Among 25 informative cases, five (20%) showed LOH. These results indicate that BACH2 plays important roles in regulation of B cell development...
  12. pmc Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice
    A Matsumoto
    Institute of Life Science, Kurume University, Kurume 839 0861, Japan
    Mol Cell Biol 19:6396-407. 1999
    ..These data suggest that CIS1 functions as a specific negative regulator of STAT5 in vivo and plays an important regulatory role in the liver, mammary glands, and T cells...
  13. ncbi request reprint Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis
    T Taniguchi
    Fourth Department of Internal Medicine, The Department of Pathology, The Branch Hospital, School of Medicine, Tokyo, Japan
    Blood 93:4167-78. 1999
    ..These observations suggest that a complex lineage-specific regulation is involved in p21 and p27 expression and that these inhibitors are involved in cell-cycle exit in megakaryocytes...
  14. ncbi request reprint Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes
    S Hasegawa
    Department of Immunology, Juntendo University, School of Medicine, Tokyo, Japan
    Blood 93:2543-51. 1999
    ..Taken together, these results suggest a novel and important role for human platelets in perpetuating allergic inflammation through the expression of and activation via the FcepsilonRI...