Masafumi Morimoto

Summary

Affiliation: Kyoto Prefectural University of Medicine
Country: Japan

Publications

  1. ncbi request reprint SCN1A mutation mosaicism in a family with severe myoclonic epilepsy in infancy
    Masafumi Morimoto
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsia 47:1732-6. 2006
  2. ncbi request reprint Ring chromosome 14 with localization-related epilepsy: three cases
    Masafumi Morimoto
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsia 44:1245-9. 2003
  3. ncbi request reprint Infantile spasms in a patient with williams syndrome and craniosynostosis
    Masafumi Morimoto
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsia 44:1459-62. 2003
  4. ncbi request reprint Imaging analysis of mineralocorticoid receptor and importins in single living cells by using GFP color variants
    Masayuki Tanaka
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Cell Tissue Res 320:447-53. 2005
  5. doi request reprint Effects of chemotherapy on the brain in childhood: diffusion tensor imaging of subtle white matter damage
    Shigemi Morioka
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Neuroradiology 55:1251-7. 2013
  6. doi request reprint Development of corpus callosum in preterm infants is affected by the prematurity: in vivo assessment of diffusion tensor imaging at term-equivalent age
    Tatsuji Hasegawa
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Pediatr Res 69:249-54. 2011
  7. doi request reprint Low-grade intraventricular hemorrhage disrupts cerebellar white matter in preterm infants: evidence from diffusion tensor imaging
    Takashi Morita
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Neuroradiology 57:507-14. 2015
  8. doi request reprint Fiber-tracking techniques can predict the degree of neurologic impairment for periventricular leukomalacia
    Aki Murakami
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo, Kyoto 602 8566, Japan
    Pediatrics 122:500-6. 2008
  9. doi request reprint Alternative psychosis and dysgraphia accompanied by forced normalization in a girl with occipital lobe epilepsy
    Yoshifumi Hirashima
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsy Behav 12:481-5. 2008
  10. doi request reprint Wernicke's encephalopathy in a patient with nephrotic syndrome
    Masashi Nishida
    Department of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Eur J Pediatr 168:731-4. 2009

Collaborators

Detail Information

Publications22

  1. ncbi request reprint SCN1A mutation mosaicism in a family with severe myoclonic epilepsy in infancy
    Masafumi Morimoto
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsia 47:1732-6. 2006
    ..To investigate the genetic background of familial severe myoclonic epilepsy in infancy (SMEI) cases...
  2. ncbi request reprint Ring chromosome 14 with localization-related epilepsy: three cases
    Masafumi Morimoto
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsia 44:1245-9. 2003
    ..In all three cases, seizures were resistant to common antiepileptic drugs...
  3. ncbi request reprint Infantile spasms in a patient with williams syndrome and craniosynostosis
    Masafumi Morimoto
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsia 44:1459-62. 2003
    ..Thyrotropin-releasing hormone (TRH) therapy reduced his seizures and improved the findings of EEG without cardiac side effects. In addition, his psychomotor development was slightly improved...
  4. ncbi request reprint Imaging analysis of mineralocorticoid receptor and importins in single living cells by using GFP color variants
    Masayuki Tanaka
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Cell Tissue Res 320:447-53. 2005
    ..This is the first visual evidence of the nuclear import of MR in association with importin alpha in single living cells...
  5. doi request reprint Effects of chemotherapy on the brain in childhood: diffusion tensor imaging of subtle white matter damage
    Shigemi Morioka
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Neuroradiology 55:1251-7. 2013
    ..We aimed to determine whether chemotherapy affects white matter (WM)...
  6. doi request reprint Development of corpus callosum in preterm infants is affected by the prematurity: in vivo assessment of diffusion tensor imaging at term-equivalent age
    Tatsuji Hasegawa
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Pediatr Res 69:249-54. 2011
    ..We demonstrated that preterm infants without apparent white matter lesions affect development of the posterior CC depending on the degree of prematurity...
  7. doi request reprint Low-grade intraventricular hemorrhage disrupts cerebellar white matter in preterm infants: evidence from diffusion tensor imaging
    Takashi Morita
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Neuroradiology 57:507-14. 2015
    ..However, a direct effect of low-grade IVH on cerebellar development is unknown. Thus, we evaluated the cerebellar and cerebral white matter (WM) of preterm infants with low-grade IVH...
  8. doi request reprint Fiber-tracking techniques can predict the degree of neurologic impairment for periventricular leukomalacia
    Aki Murakami
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo, Kyoto 602 8566, Japan
    Pediatrics 122:500-6. 2008
    ..Such episodes can result in periventricular leukomalacia, which may substantially influence later brain development. Noninvasive methods of assessing the severity of injury at the earliest stage of life have not yet been established...
  9. doi request reprint Alternative psychosis and dysgraphia accompanied by forced normalization in a girl with occipital lobe epilepsy
    Yoshifumi Hirashima
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Epilepsy Behav 12:481-5. 2008
    ..It is assumed that abnormal discharges in the left occipital lobe were projected into the left posterior inferior temporal area and that a functional disorder in that area led to dysgraphia; however, further exploration is needed...
  10. doi request reprint Wernicke's encephalopathy in a patient with nephrotic syndrome
    Masashi Nishida
    Department of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Eur J Pediatr 168:731-4. 2009
    ..This case suggests the need to consider WE as a possible serious complication in patients with NS, and also emphasizes the usefulness of MRI in the diagnosis of WE, especially in pediatric cases with complex clinical symptoms...
  11. ncbi request reprint [Recurrence of transient splenial lesions in a child with "benign convulsions with gastroenteritis"]
    Shigemi Morioka
    Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto
    No To Hattatsu 42:449-53. 2010
    ..Diffusion-weighted magnetic resonance imaging of the brain demonstrated hyperintense lesions in the splenium of the corpus callosum, which disappeared within a week. We speculate that CwG is likely to lead to transient splenial lesions...
  12. doi request reprint Effects of stress of postnatal development on corticosterone, serotonin and behavioral changes
    Fumihiro Matsui
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto 602 8566, Japan
    Brain Dev 32:517-23. 2010
    ..Stress during the PND 11-15 period may enhance later anxiety-related behaviors without altering 5-HT and 5-HIAA content...
  13. ncbi request reprint Infantile bilateral striatal necrosis associated with human herpes virus-6 (HHV-6) infection
    Aki Murakami
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kawaramachi Horikoji, Kamigyo, Kyoto 602 8566, Japan
    Brain Dev 27:527-30. 2005
    ..In addition, the serum HHV-6 IgM class antibody level was significantly increased. The patient is thought to be the first case of HHV-6 infection related infantile bilateral striatal necrosis (IBSN)...
  14. doi request reprint Intestinal pseudo-obstruction in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) associated with phenytoin therapy
    Tomohiro Chiyonobu
    Department of Pediatrics, Akashi Municipal Hospital, 1 33 Takasho machi, Akashi, Hyogo 673 8501, Japan
    Brain Dev 30:430-3. 2008
    ..Careful clinical observation including gastrointestinal symptoms is required in the management of epilepsy in MELAS patients...
  15. pmc Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs
    Michiko Yoshida
    Department of Clinical Application, Center for iPS Cell Research and Application CiRA, Kyoto University, Kyoto 606 8507, Japan Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Stem Cell Reports 4:561-8. 2015
    ..Thus, the current in vitro model of AChR clustering using SMA patient-derived iPSCs is useful to dissect the pathophysiological mechanisms underlying the development of SMA, and to evaluate the efficacy of new therapeutic approaches. ..
  16. doi request reprint Glycosylphosphatidylinositol (GPI) anchor deficiency caused by mutations in PIGW is associated with West syndrome and hyperphosphatasia with mental retardation syndrome
    Tomohiro Chiyonobu
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kamigyo, Kyoto, Japan
    J Med Genet 51:203-7. 2014
    ....
  17. doi request reprint T295M-associated Glut1 deficiency syndrome with normal erythrocyte 3-OMG uptake
    Tatsuya Fujii
    Department of Pediatrics, Shiga Medical Center for Children, 5 7 30 Moriyama, Shiga, Japan
    Brain Dev 33:316-20. 2011
    ..We compared the phenotype of three T295M-associated patients with that of other Glut1-deficient patients...
  18. ncbi request reprint Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats
    Tomohiro Aoki
    Kyoto University, Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo ku, Kyoto, Japan
    Stroke 38:162-9. 2007
    ..Matrix metalloproteinases (MMPs) are a family of proteinases which are involved in the remodeling of vascular walls. In the present study, we investigated the significance of MMPs in the progression of cerebral aneurysms...
  19. ncbi request reprint Effects of edaravone on N-methyl-D-aspartate (NMDA)-mediated cytochrome c release and apoptosis in neonatal rat cerebrocortical slices
    Yumi Nakano-Okuda
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan
    Int J Dev Neurosci 24:349-56. 2006
    ..2+/-2.1%). Edaravone's reduction in TUNEL staining and cytochrome c release provides evidence of reactive oxygen species mechanisms and antioxidant benefits in cytochrome c-mediated apoptosis during N-methyl-D-aspartate excitotoxicity...
  20. ncbi request reprint Yellow fluorescent protein-tagged and cyan fluorescent protein-tagged imaging analysis of glucocorticoid receptor and importins in single living cells
    Masayuki Tanaka
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Endocrinology 144:4070-9. 2003
    ..However, direct interaction between GR and importin-beta was not detected. These studies showed visual evidence of the nuclear importing of GR in association with importin-alpha in single living cells...
  21. ncbi request reprint Mouse model of cerebral aneurysm: experimental induction by renal hypertension and local hemodynamic changes
    Masafumi Morimoto
    Departments of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Stroke 33:1911-5. 2002
    ..To make possible genetic analysis of CA formation with genetically altered mice, we have successfully established a mouse model of saccular CA that recapitulates the essential features of human saccular CA...
  22. pmc Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11
    Christian R Marshall
    Program in Genetics and Genomic Biology and The Centre for Applied Genomics, Hospital for Sick Children, Toronto, ON M5G 1L7, Canada
    Am J Hum Genet 83:106-11. 2008
    ..MAGI2 encodes the synaptic scaffolding protein membrane-associated guanylate kinase inverted-2 that interacts with Stargazin, a protein also associated with epilepsy in the stargazer mouse...