T Maoka

Summary

Affiliation: Kyoto City Hospital
Country: Japan

Publications

  1. ncbi request reprint Characterization and singlet oxygen quenching activity of (3R)-3-hydroxy-4-ketotorulene and (3R)-3-hydroxy-4-keto-γ-carotene isolated from the yeast Xanthophyllomyces dendrorhrous
    Takashi Maoka
    Research Institute for Production Development, Division of Food Function and Chemistry, Kyoto, Japan
    J Oleo Sci 61:401-6. 2012
  2. doi request reprint Carotenoids of Sea Angels Clione limacina and Paedoclione doliiformis from the Perspective of the Food Chain
    Takashi Maoka
    Research Institute for Production Development, Shimogamo Morimoto cho 15, Sakyo ku, Kyoto 606 0805, Japan
    Mar Drugs 12:1460-70. 2014
  3. ncbi request reprint Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin
    Takashi Maoka
    Research Institute for Production Development, Sakyou ku, Kyoto 607 0805, Japan
    J Oleo Sci 62:181-6. 2013
  4. pmc Anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of nitroastaxanthin and nitrolutein, the reaction products of astaxanthin and lutein with peroxynitrite
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Mar Drugs 10:1391-9. 2012
  5. ncbi request reprint Identification of carotenoids in the freshwater shellfish Unio douglasiae nipponensis, Anodonta lauta, Cipangopaludina chinensis laeta, and Semisulcospira libertina
    Takashi Maoka
    Research Institute for Production Development, Japan
    J Oleo Sci 61:69-74. 2012
  6. doi request reprint A series of 19'-hexanoyloxyfucoxanthin derivatives from the sea mussel, Mytilus galloprovincialis, grown in the Black Sea, Ukraine
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Agric Food Chem 59:13059-64. 2011
  7. doi request reprint Sterically hindered carotenoids with 3Z, 5Z configuration from the seeds of oriental bitter sweet, Celastrus orbiculatus
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Phytochemistry 70:920-3. 2009
  8. doi request reprint New C37 skeletal carotenoid from the clam, Paphia amabillis
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Agric Food Chem 56:12069-72. 2008
  9. doi request reprint Pittosporumxanthins, cycloaddition products of carotenoids with alpha-tocopherol from seeds of Pittosporum tobira
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Nat Prod 71:622-7. 2008
  10. ncbi request reprint 5-Hydroxy-seco-carotenoids from Pittosporum tobira
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Phytochemistry 67:2120-5. 2006

Collaborators

Detail Information

Publications59

  1. ncbi request reprint Characterization and singlet oxygen quenching activity of (3R)-3-hydroxy-4-ketotorulene and (3R)-3-hydroxy-4-keto-γ-carotene isolated from the yeast Xanthophyllomyces dendrorhrous
    Takashi Maoka
    Research Institute for Production Development, Division of Food Function and Chemistry, Kyoto, Japan
    J Oleo Sci 61:401-6. 2012
    ..Both 1 and 2 showed potent singlet oxygen (¹O₂) quenching activity as that of astaxanthin and lycopene, which were well known strong ¹O₂ quencher...
  2. doi request reprint Carotenoids of Sea Angels Clione limacina and Paedoclione doliiformis from the Perspective of the Food Chain
    Takashi Maoka
    Research Institute for Production Development, Shimogamo Morimoto cho 15, Sakyo ku, Kyoto 606 0805, Japan
    Mar Drugs 12:1460-70. 2014
    ..limacina and P. doliiformis. Sea angels oxidatively metabolize dietary carotenoids and accumulate them in their gonads. Carotenoids in the gonads of sea angels might protect against oxidative stress and enhance reproduction. ..
  3. ncbi request reprint Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin
    Takashi Maoka
    Research Institute for Production Development, Sakyou ku, Kyoto 607 0805, Japan
    J Oleo Sci 62:181-6. 2013
    ....
  4. pmc Anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of nitroastaxanthin and nitrolutein, the reaction products of astaxanthin and lutein with peroxynitrite
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Mar Drugs 10:1391-9. 2012
    ..These activities were slightly higher than those of astaxanthin. Similar results were obtained for the 15-nitrolutein, a major reaction product of lutein with peroxynitrite...
  5. ncbi request reprint Identification of carotenoids in the freshwater shellfish Unio douglasiae nipponensis, Anodonta lauta, Cipangopaludina chinensis laeta, and Semisulcospira libertina
    Takashi Maoka
    Research Institute for Production Development, Japan
    J Oleo Sci 61:69-74. 2012
    ..In contrast, lutein and zeaxanthin were found to be the major carotenoids in C. chinensis laeta. In addition, a series of keto carotenoids was also identified in S. libertina...
  6. doi request reprint A series of 19'-hexanoyloxyfucoxanthin derivatives from the sea mussel, Mytilus galloprovincialis, grown in the Black Sea, Ukraine
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Agric Food Chem 59:13059-64. 2011
    ..These structures were charcterized by UV-vis, fast atom bombardment mass spectrometry, circular dichroism, and (1)H NMR spectroscopic data. They were assumed to be metabolites of 19'-hexanoyloxyfucoxanthin (1)...
  7. doi request reprint Sterically hindered carotenoids with 3Z, 5Z configuration from the seeds of oriental bitter sweet, Celastrus orbiculatus
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Phytochemistry 70:920-3. 2009
    ..This is the first report on carotenoids with a 3Z, 5Z configuration...
  8. doi request reprint New C37 skeletal carotenoid from the clam, Paphia amabillis
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Agric Food Chem 56:12069-72. 2008
    ..The fatty acids esterified with hydratopyrrhoxanthinol were assigned as C22:6, C20:1, C20:4, C20:5, C18:0, C18:1, C17:0, C16:0, C16:1, and C14:0 on the basis of FAB-MS data...
  9. doi request reprint Pittosporumxanthins, cycloaddition products of carotenoids with alpha-tocopherol from seeds of Pittosporum tobira
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Nat Prod 71:622-7. 2008
    ..Compounds 3, 5, and 7 were assigned (11' R,12' S) and 4, 6, and 8 (11' S,12' R) absolute configurations using CD measurements...
  10. ncbi request reprint 5-Hydroxy-seco-carotenoids from Pittosporum tobira
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Phytochemistry 67:2120-5. 2006
    ....
  11. ncbi request reprint Carotenoids and their fatty acid esters of spiny lobster Panulirus japonicus
    Takashi Maoka
    Research Institute for Production Development, Kyoto, Japan
    J Oleo Sci 57:145-52. 2008
    ..Furthermore, 2,3-didehydrocanthaxanthin (4) was first identified as a natural product...
  12. ncbi request reprint Carotenoids with a 5,6-dihydro-5,6-dihydroxy-beta-end group, from yellow sweet potato "Benimasari", Ipomoea batatas Lam
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Phytochemistry 68:1740-5. 2007
    ....
  13. ncbi request reprint Structure of new carotenoids with a 3,4-dihydroxy-beta-end group from the oyster Crassostrea gigas
    Takashi Maoka
    Research Institute for Production Development 15 Shimogama morimoto cho, Sakyo ku, Kyoto 606 0805, Japan
    Chem Pharm Bull (Tokyo) 53:1207-9. 2005
    ....
  14. ncbi request reprint Structure of new carotenoids from corbicula clam Corbicula japonica
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Nat Prod 68:1341-4. 2005
    ..Their structures were determined by chemical and spectral data...
  15. ncbi request reprint Carotenoids in three species of Corbicula Clams, Corbicula japonica, Corbicula sandai, and Corbicula sp. (Chinese Freshwater Corbicula Clam)
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Agric Food Chem 53:8357-64. 2005
    ..They were assumed to be peculiar carotenoids in corbicula clams...
  16. ncbi request reprint 2,3'-Dihydroxycanthaxanthin, a new carotenoid with a 2-hydroxy-4-oxo-beta-end group from the hermit crab, Paralithodes brevipes
    Takashi Maoka
    Research Institute for Production Development, Kyoto, Japan
    Chem Pharm Bull (Tokyo) 54:1462-4. 2006
    ..Chiral resolution of 1 by HPLC using a chiral column provided two stereoisomers, 1a and 1b. The 3'R and 3'S chirality were determined for 1a and 1b, respectively, by CD spectra...
  17. doi request reprint Structure of minor carotenoids from the crown-of-thorns starfish, Acanthaster planci
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Nat Prod 73:675-8. 2010
    ..Their structures were determined on the basis of chemical and spectroscopic data...
  18. ncbi request reprint Structure of new carotenoids with the 6-oxo-kappa end group from the fruits of paprika, Capsicum annuum
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Nat Prod 67:115-7. 2004
    ..The structures of 1 and 2 were determined to be (3R,5'R)-3-hydroxy-beta,kappa-caroten-6'-one and (5'R)-3,4-didehydro-beta,kappa-caroten-6'-one, respectively, from UV-vis, NMR, CD, HRFABMS, and FABMS/MS spectra...
  19. ncbi request reprint Isolation of a series of apocarotenoids from the fruits of the red paprika Capsicum annuum L
    T Maoka
    Kyoto Pharmaceutical University, Misasagi, Yamashina ku, Kyoto 607 8412, Japan
    J Agric Food Chem 49:1601-6. 2001
    ..These apocarotenoids were assumed to be oxidative cleavage products of C(40) carotenoid such as capsanthin in paprika...
  20. ncbi request reprint Capsanthone 3,6-epoxide, a new carotenoid from the fruits of the red paprika Capsicum annuum L
    T Maoka
    Kyoto Pharmaceutical University, Misasagi, Yamashina ku, Kyoto 607 8412, Japan
    J Agric Food Chem 49:3965-8. 2001
    ..Capsanthone 3,6-epoxide is assumed to be an oxidative metabolite of capsanthin 3,6-epoxide in paprika...
  21. ncbi request reprint Cancer chemopreventive activity of carotenoids in the fruits of red paprika Capsicum annuum L
    T Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, 606 0805, Kyoto, Japan
    Cancer Lett 172:103-9. 2001
    ....
  22. doi request reprint Recent progress in structural studies of carotenoids in animals and plants
    Takashi Maoka
    Research Institute for Production Development, Food Function and Chemistry, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Arch Biochem Biophys 483:191-5. 2009
    ..The present paper provides a review of new structural carotenoids isolated from aquatic animals and higher plants by our group over the last five years...
  23. ncbi request reprint Isolation and characterization of dinochrome A and B, anti-carcinogenic active carotenoids from the fresh Water red tide Peridinium bipes
    Takashi Maoka
    Kyoto Pharamceutical University, Kyoto, Japan
    Chem Pharm Bull (Tokyo) 50:1630-3. 2002
    ..Furthermore, dinochrome A was found to inhibit the proliferation of human malignant tumor cells, such as GOTO, OST and HeLa cells...
  24. pmc Carotenoids in marine animals
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Mar Drugs 9:278-93. 2011
    ....
  25. ncbi request reprint Carotenoids and their fatty acid esters in the petals of Adonis aestivalis
    Takashi Maoka
    Research Institute for Production Development, Kyoto, Japan
    J Oleo Sci 60:47-52. 2011
    ..8%, free: 0.3%) were identified as the major components. The fatty acids esterified with astaxanthin and adonirubin were assigned as C18:0, C18:1, C16:0, C16:1, C14:0, C12:0, and C10:0 from the FAB-MS spectral data...
  26. doi request reprint Carotenoids in clams, Ruditapes philippinarum and Meretrix petechialis
    Takashi Maoka
    Research Institute for Production Development, Sakyo ku, Kyoto, Japan
    J Agric Food Chem 58:5784-8. 2010
    ..Crassostreaxanthin A 3-acetate and crassostreaxanthin B 3-acetate were first isolated and completely characterized by spectroscopic data. Furthermore, possible metabolic pathways of fucoxanthin in clams were proposed...
  27. ncbi request reprint Structures of carotenoids with 5,6-dihydro-beta-end groups from the spindle shell Fusinus perplexus
    M Tsushima
    Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607 8414, Japan
    J Nat Prod 64:1139-42. 2001
    ....
  28. ncbi request reprint Structures of five new carotenoids from the oyster Crassostrea gigas
    T Maoka
    Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan
    J Nat Prod 64:578-81. 2001
    ..In the FAB-MS/MS of 2-4, having the 5-hydroxy-3,6-epoxy-5,6-dihydro-beta-carotene moiety, the characteristic product ions resulting from the sequential cleavage of C-C bonds in the polyene chain were observed...
  29. ncbi request reprint Structure of three new carotenoids with a 3-methoxy-5-keto-5,6-seco-4,6-cyclo-beta end group from the seeds of Pittosporum tobira
    Y Fujiwara
    Kyoto Pharmaceutical University, Japan
    Chem Pharm Bull (Tokyo) 49:985-7. 2001
    ..Three new carotenoids with a 3-methoxy-5-keto-5,6-seco-4,6-cyclo-beta end group (1-3) have been isolated from the seeds of Pittosporum tobira. Their structures were elucidated by detailed analyses of nuclear magnetic resonance and UV data...
  30. ncbi request reprint Isolation of stereoisomeric epoxy carotenoids and new acetylenic carotenoid from the common freshwater goby Rhinogobius brunneus
    M Tsushima
    Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607 8412, Japan
    J Nat Prod 63:960-4. 2000
    ..Furthermore, a new acetylenic triol carotenoid, gobiusxanthin (3), was obtained, and its structure was determined to be 7,8-didehydro-beta, epsilon-carotene-3,3', 6'-triol by chemical and spectral data...
  31. ncbi request reprint Salmoxanthin, deepoxysalmoxanthin, and 7,8-didehydrodeepoxysalmoxanthin from the Salmon Oncorhynchus keta
    T Matsuno
    Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto 607-8412, Japan
    J Nat Prod 64:507-10. 2001
    ....
  32. ncbi request reprint Reinvestigation of structure of porritoxin, a phytotoxin of Alternaria porri
    Masayuki Horiuchi
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyoku, Kyoto 606 0805, Japan
    J Nat Prod 65:1204-5. 2002
    ..Thus our previous proposed structure, 8-(3',3'-dimethylallyloxy)-10-methoxy-9-methyl-1H-3,4-dihydro-2,5-benzoxazocin-6(5H)-one (2), is incorrect...
  33. ncbi request reprint New bis-secolabdane diterpenoids from Excoecaria agallocha
    Tenji Konishi
    Kyoto Pharmaceutical University, 5 Nakauchi cho, Misasagi, Yamashina ku, Kyoto 607 8414, Japan
    J Nat Prod 66:108-11. 2003
    ..The structures of 1 and 2 were established on the basis of spectroscopic data interpretation and chemical evidence...
  34. ncbi request reprint Porritoxins, metabolites of Alternaria porri, as anti-tumor-promoting active compounds
    Masayuki Horiuchi
    Research Institute for Production Development, Sakyo ku, Kyoto 606 0805, Japan
    Nat Prod Res 20:161-6. 2006
    ..Inhibitory effect of porritoxin (1) and (2) was superior to that of beta-carotene, a well-known anti-tumor promoter. Furthermore, the structure-activity correlation of porritoxins and their related compounds were discussed...
  35. ncbi request reprint Characterization of fucoxanthin and fucoxanthinol esters in the Chinese surf clam, Mactra chinensis
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    J Agric Food Chem 55:1563-7. 2007
    ..The fatty acids esterified with fucoxanthin and fucoxanthinol were identified as C24:6, C22:5, C22:6, C20:5, C20:0, C20:1, C18:0, C18:1, C16:0, C16:1, and C14:0 by FAB-MS data...
  36. ncbi request reprint New quinone sulfates from the crinoids Tropiometra afra macrodiscus and Oxycomanthus japonicus
    Daizo Takahashi
    Kyoto Pharmaceutical University, Kyoto, Japan
    Chem Pharm Bull (Tokyo) 50:1609-12. 2002
    ..Ptilometric acid 6-O-sulfate (1) showed an antifeedant activity on fish...
  37. pmc Astaxanthin ameliorates heat stress-induced impairment of blastocyst development in vitro:--astaxanthin colocalization with and action on mitochondria--
    T Kuroki
    Laboratory of Animal Physiology and Functional Anatomy, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
    J Assist Reprod Genet 30:623-31. 2013
    ....
  38. ncbi request reprint Characterization of epoxy carotenoids by fast atom bombardment collision-induced dissociation MS/MS
    Takashi Maoka
    Research Institute for Production Development, Kyoto 606 0805, Japan
    Lipids 39:179-83. 2004
    ....
  39. pmc Carotenoids in marine invertebrates living along the Kuroshio current coast
    Takashi Maoka
    Research Institute for Production Development, 15 Shimogamo Morimoto Cho, Sakyo ku, Kyoto 606 0805, Japan
    Mar Drugs 9:1419-27. 2011
    ..Carotenoids found in these marine animals closely reflected not only their metabolism but also their food chains...
  40. ncbi request reprint Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice
    Wataru Aoi
    Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, 602 0841, Japan
    Antioxid Redox Signal 5:139-44. 2003
    ..Astaxanthin can attenuate exercise-induced damage in mouse skeletal muscle and heart, including an associated neutrophil infiltration that induces further damage...
  41. ncbi request reprint Reaction of retinol with peroxynitrite
    Rie Suzuki
    Faculty of Agriculture, Shizuoka University, Japan
    Biosci Biotechnol Biochem 71:2596-9. 2007
    ..From these results, it was observed that retinol can undergo a nitration reaction with peroxynitrite. Furthermore, the formation mechanisms of 1, 2, and 3 from retinol with peroxynitrite are discussed...
  42. ncbi request reprint Allenic and cumulenic lipids
    Valery M Dembitsky
    Department of Medicinal Chemistry and Natural Products, School of Pharmacy, P O Box 12065, Hebrew University, Jerusalem 91120, Israel
    Prog Lipid Res 46:328-75. 2007
    ..This review emphasizes the role of natural and synthetic allenic and cumulenic lipids and other related compounds as an important source of leads for drug discovery...
  43. pmc Substrate specificities and availability of fucosyltransferase and beta-carotene hydroxylase for myxol 2'-fucoside synthesis in Anabaena sp. strain PCC 7120 compared with Synechocystis sp. strain PCC 6803
    Mari Mochimaru
    Department of Natural Sciences, Komazawa University, Tokyo 154 8525, Japan
    J Bacteriol 190:6726-33. 2008
    ..Thus, the substrate specificities or substrate availabilities of both fucosyltransferase and CrtR were different in these species. The biosynthetic pathways of carotenoids in Anabaena sp. strain PCC 7120 are discussed...
  44. ncbi request reprint Major carotenoid isolated from Paracoccus schoinia NBRC 100637T is adonixanthin diglucoside
    Shinichi Takaichi
    Biological Laboratory, Nippon Medical School, Kosugi cho 2, Nakahara, Kawasaki 211 0063, Japan
    J Nat Prod 69:1823-5. 2006
    ..The minor carotenoids in this bacterium included astaxanthin diglucoside, zeaxanthin diglucoside, canthaxanthin, echinenone, zeaxanthin, beta-cryptoxanthin, and beta-carotene...
  45. doi request reprint Diapolycopenedioic acid xylosyl esters A, B, and C, novel antioxidative glyco-C30-carotenoic acids produced by a new marine bacterium Rubritalea squalenifaciens
    Kazutoshi Shindo
    Department of Food and Nutrition, Japan Women s University, Bunkyo ku, Tokyo, Japan
    J Antibiot (Tokyo) 61:185-91. 2008
    ..Diapolycopenedioic acid xylosyl ester A showed potent antioxidative activity in a (1)O(2) suppression model...
  46. ncbi request reprint Analysis of carotenoid composition in petals of calendula (Calendula officinalis L.)
    Sanae Kishimoto
    National Institute of Floricultural Science, Ibaraki, Japan
    Biosci Biotechnol Biochem 69:2122-8. 2005
    ..Additionally, (5Z,9Z,5'Z)-lycopene (2) has been reported only as a synthesized compound...
  47. ncbi request reprint Presence of free myxol and 4-hydroxymyxol and absence of myxol glycosides in Anabaena variabilis ATCC 29413, and proposal of a biosynthetic pathway of carotenoids
    Shinichi Takaichi
    Biological Laboratory, Nippon Medical School, Kawasaki, 211 0063 Japan
    Plant Cell Physiol 47:211-6. 2006
    ..variabilis ATCC 29413, we proposed a biosynthetic pathway of the carotenoids and the corresponding genes and enzymes. The homologous genes were searched by sequence homology only from the functionally confirmed genes...
  48. ncbi request reprint Structure of beta-glucan oligomer from laminarin and its effect on human monocytes to inhibit the proliferation of U937 cells
    Zhongcun Pang
    Graduate School of Agriculture, Kyoto Prefectural University, Japan
    Biosci Biotechnol Biochem 69:553-8. 2005
    ..3:1. These results indicate that the beta-1,3-glucan oligomer with a higher content of beta-1,6-linkage stimulates monocytes to inhibit the proliferation of U937 cells...
  49. ncbi request reprint Halocynthiaxanthin and peridinin sensitize colon cancer cell lines to tumor necrosis factor-related apoptosis-inducing ligand
    Tatsushi Yoshida
    Department of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Mol Cancer Res 5:615-25. 2007
    ..These results indicate that the combination of certain carotenoids and TRAIL is a new strategy to overcome TRAIL resistance in cancer cells...
  50. ncbi request reprint The cyanobacterium Gloeobacter violaceus PCC 7421 uses bacterial-type phytoene desaturase in carotenoid biosynthesis
    Tohru Tsuchiya
    Department of Technology and Ecology, Hall of Global Environmental Research, Kyoto University, Kyoto 606 8501, Japan
    FEBS Lett 579:2125-9. 2005
    ..We also revealed that echinenone synthesis is catalyzed by CrtW rather than CrtO. These findings indicated that Gloeobacter retains ancestral properties of carotenoid biosynthesis...
  51. pmc Malaria parasites giving rise to recrudescence in vitro
    Shusuke Nakazawa
    Institute of Tropical Medicine, Nagasaki University, Sakamoto 1 12 4, Nagasaki 852 8523, Japan
    Antimicrob Agents Chemother 46:958-65. 2002
    ..These results suggest that a parasite culture may contain parasites in some phases that are not killed by drug for up to 10 days, which explains the recrudescences that occur even after treatment...
  52. ncbi request reprint Suppressive effects of alloxanthin and diatoxanthin from Halocynthia roretzi on LPS-induced expression of pro-inflammatory genes in RAW264.7 cells
    Izumi Konishi
    Faculty of Fisheries Sciences, Hokkaido University, Hokkaido, Japan
    J Oleo Sci 57:181-9. 2008
    ..7 cells induced by LPS. The suppressive effects of these carotenoids were remarkable compared to those of beta-carotene and zeaxanthin...
  53. ncbi request reprint Novel carotenoid glucoside esters from alkaliphilic heliobacteria
    Shinichi Takaichi
    Biological Laboratory, Nippon Medical School, Nakahara, Kawasaki 211 0063, Japan
    Arch Microbiol 179:95-100. 2003
    ..The non-alkaliphilic species Heliophilum fasciatum also contained trace amounts of the two OH-diaponeurosporene glucoside esters. The results are used to predict the pathway of carotenoid biosynthesis in heliobacteria...
  54. ncbi request reprint Guaiacylglycerol-7'-O-methyl 8'-vanillic acid ether and related compounds from Boreava orientalis
    Akiyo Sakushima
    Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari Tobetsu, Hokkaido 061 0293, Japan
    Phytochem Anal 14:48-53. 2003
    ..Structural determinations were made on the basis of UV, MS, 1H- and 13C-NMR spectral data, including two-dimensional shift correlation. The relative configurations were assigned on the basis of 1H-NMR chemical shifts...
  55. ncbi request reprint Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice
    Yuji Naito
    Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto 602 8566, Japan
    Biofactors 20:49-59. 2004
    ..In conclusion, administration of astaxanthin might be a novel approach for the prevention of diabetes nephropathy...
  56. ncbi request reprint Production of phytoene, a carotenoid, and induction of connexin 26 in transgenic mice carrying the phytoene synthase gene crtB
    Yoshiko Satomi
    Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Biochem Biophys Res Commun 320:398-401. 2004
    ..Phytoene-producing mice provide a useful system in which to investigate the in vivo function of the carotenoid phytoene...
  57. doi request reprint Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells
    Yukihiro Yamamoto
    Faculty of Fisheries Sciences, Hokkaido University, 3 1 1 Minato, Hakodate, Hokkaido 041 8611, Japan
    Bioorg Med Chem Lett 18:4044-6. 2008
    ..The synthetic phosphatidylated monoterpenes showed a markedly antiproliferative effect on human prostate PC-3 and human leukemia HL-60 cells at 100 microM, while the free monoterpene alcohols had no effect at 400 microM...
  58. ncbi request reprint Myxol and 4-ketomyxol 2'-fucosides, not rhamnosides, from Anabaena sp. PCC 7120 and Nostoc punctiforme PCC 73102, and proposal for the biosynthetic pathway of carotenoids
    Shinichi Takaichi
    Biological Laboratory, Nippon Medical School, Kawasaki, 211 0063 Japan
    Plant Cell Physiol 46:497-504. 2005
    ..Finally, we investigated the phylogenetic relationships among some Anabaena and Nostoc species, including some newly isolated species...
  59. ncbi request reprint Carotenoid composition in petals of chrysanthemum (Dendranthema grandiflorum (Ramat.) Kitamura)
    Sanae Kishimoto
    National Institute of Floricultural Science, Fujimoto 2 1, Tsukuba, Ibaraki 305 8519, Japan
    Phytochemistry 65:2781-7. 2004
    ..The analyses indicate that carotenoids from the petals of chrysanthemum have a very characteristic composition...