Research Topics
Genomes and GenesSpecies | K KitayaSummaryAffiliation: Kyoto Prefectural University of Medicine Country: Japan Publications
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Detail Information
Publications
Effect of female sex steroids on human endometrial CD16neg CD56bright natural killer cellsKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Fertil Steril 79:730-4. 2003..To clarify whether female sex steroids directly affect the bioactivity of the human endometrial CD16neg CD56bright natural killer (NK) cells...
Expression of macrophage inflammatory protein-3beta in human endometrium throughout the menstrual cycleNobue Daikoku
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kajii cho 465, Kamigyo ku, Kyoto, Japan 602 8566
Fertil Steril 81:876-81. 2004..To determine the expression of macrophage inhibitory protein-3beta (MIP-3beta), a potential chemoattractant for endometrial natural killer (NK) cells, in the human endometrium...
Immunohistochemistrical and clinicopathological characterization of chronic endometritisKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kajii cho, Kamigyo ku, Japan
Am J Reprod Immunol 66:410-5. 2011..Using immunohistochemistry for full-thickness endometrium, we sought for its clinicopathological features...
Pathophysiological roles of chemokines in human reproduction: an overviewKotaro Kitaya
Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
Am J Reprod Immunol 65:449-59. 2011..The aim of this review is to update the knowledge on chemokines in male and female genital organs, with a focus on their potential pathophysiological roles in human reproduction...
Prevalence of chronic endometritis in recurrent miscarriagesKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Fertil Steril 95:1156-8. 2011..3% of patients with recurrent miscarriages (in 12.9% of patients with miscarriages of unknown etiology). Chronic endometritis is not negligible in patients with recurrent miscarriages...
Aberrant expression of selectin E, CXCL1, and CXCL13 in chronic endometritisKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
Mod Pathol 23:1136-46. 2010..These findings indicated that the aberrant local microenvironment triggered possibly by bacterial infection has a role in selective extravasation of circulating B cells in chronic endometritis...
Leukocyte density and composition in human cycling endometrium with uterine fibroidsKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Hum Immunol 71:158-63. 2010..The leukocyte density and composition in the endometrium with UF are different from those without UF, suggesting their local effects on endometrial leukocyte population...
Dermatan sulfate proteoglycan biglycan as a potential selectin L/CD44 ligand involved in selective recruitment of peripheral blood CD16(-) natural killer cells into human endometriumKotaro Kitaya
Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
J Leukoc Biol 85:391-400. 2009..These findings demonstrated that DS proteoglycan biglycan is a potential selectin L/CD44 ligand involved in tethering/rolling of peripheral blood CD16(-) NK cells on endometrial microvascular endothelial cells...
Accumulation of uterine CD16(-) natural killer (NK) cells: friends, foes, or Jekyll-and-Hyde relationship for the conceptus?Kotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Immunol Invest 37:467-81. 2008..In this review, the potential underlying mechanisms for accumulation of uCD16(-) NK cells in uncomplicated pregnancies and in pathological pregnancies, especially recurrent miscarriages, are discussed...
Genes regulated by interferon-gamma in human uterine microvascular endothelial cellsKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
Int J Mol Med 20:689-97. 2007....
Post-ovulatory rise of endometrial CD16(-) natural killer cells: in situ proliferation of residual cells or selective recruitment from circulating peripheral blood?Kotaro Kitaya
Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Obstetrics and Gynecology, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
J Reprod Immunol 76:45-53. 2007..Based upon our findings, we discuss the possibility and relevance of these two potential mechanisms...
Central role of interleukin-15 in postovulatory recruitment of peripheral blood CD16(-) natural killer cells into human endometriumKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kamigyo ku, Kyoto 602 8566, Japan
J Clin Endocrinol Metab 90:2932-40. 2005..These results support the idea that endogenous IL-15 in secretory phase endometrium plays a central role in postovulatory recruitment of PB CD16(-) NK cells into the human endometrium...
Spatial and temporal expression of ligands for CXCR3 and CXCR4 in human endometriumKotaro Kitaya
Departments of Obstetrics and Gynecology, Koto Prefectural University of Medicine, Kyoto 602 8566, Japan
J Clin Endocrinol Metab 89:2470-6. 2004..The results suggest that Mig and IP-10 may be involved in the recruitment of natural killer cells or other phenomena in the human endometrium...
Localization of interferon regulatory factor-1 in human endometrium throughout the menstrual cycleK Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Fertil Steril 75:992-6. 2001..To determine the expression and localization of IRF-1 in human endometrium throughout the menstrual cycle...
Expression of macrophage inflammatory protein-1beta in human endometrium: its role in endometrial recruitment of natural killer cellsKotaro Kitaya
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Japan
J Clin Endocrinol Metab 88:1809-14. 2003..These results suggest that endometrial MIP-1beta may be involved in the recruitment of NK cells from circulating peripheral blood...
IL-15 expression at human endometrium and deciduaK Kitaya
Department of Obstetrics and Gynecology and Dynamic Pathology Research Institute, Kyoto Prefectural University of Medicine, Kyoto, 602 8566, Japan
Biol Reprod 63:683-7. 2000..These results suggest that IL-15 expression in human uterine mucosa corresponds to the fluctuation of uterine NK cells and that its production is hormonally controlled, especially by progesterone...
Possible role of hematopoietic CD44/chondroitin sulfate interaction in extravasation of peripheral blood CD16(-) natural killer cells into human endometriumTadahiro Yasuo
Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
J Reprod Immunol 78:1-10. 2008..Serglycin may be a potential CS proteoglycan involved in this phenomenon...
Potential selectin L ligands involved in selective recruitment of peripheral blood CD16(-) natural killer cells into human endometriumTakeshi Yamaguchi
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan
Biol Reprod 74:35-40. 2006..These findings support the idea that the interaction between selectin L and selectin L ligands functions in the postovulatory selective recruitment of PB CD16(-) NK cells into the human endometrium...
Progesterone induction of chondroitin sulfate proteoglycan aggrecan expression in human endometrial epithelial cellsTadahiro Yasuo
Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kamigyo ku, Kyoto 602 8566, Japan
J Steroid Biochem Mol Biol 122:159-63. 2010..The endometrial expression pattern of aggrecan was distinct from that of other known CSPGs, suggesting the unique role of this proteoglycan at the implantation site...
Effect of ovarian steroids on gene expression profile in human uterine microvascular endothelial cellsTadahiro Yasuo
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Fertil Steril 92:709-21. 2009..To examine the effect of the ovarian steroids on the gene expression profile in human uterine microvascular endothelial cells...
Fluctuation of 6Ckine expression in human endometrium during the menstrual cycleTakeshi Nakayama
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Fertil Steril 80:1461-5. 2003..To clarify the expression of 6Ckine, a potential chemoattractant for endometrial natural killer (NK) cells, in the human endometrium...
Interferon regulatory factor-1 expression in human uterine endometrial carcinomaHaruo Kuroboshi
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kamigyo ku, 602 8566, Kyoto, Japan
Gynecol Oncol 91:354-8. 2003..The objective was to investigate the expression of interferon regulatory factors 1 (IRF-1) in human uterine endometrial carcinoma...
