Research Topics
Species | Minoru KimuraSummaryAffiliation: Kyoto Prefectural University of Medicine Country: Japan Publications
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Detail Information
Publications
Participation of the thalamic CM-Pf complex in attentional orientingTakafumi Minamimoto
Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan
J Neurophysiol 87:3090-101. 2002....- Molecular mechanism of preventive effect of peony root extract on neuron damageKatsuyoshi Sunaga
Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan
J Herb Pharmacother 4:9-20. 2004..These results suggested that an increase in A20 expression is the main molecular mechanism of protective action of peony root extract on neuron damage... - What does the habenula tell dopamine neurons?Minoru Kimura
Nat Neurosci 10:677-8. 2007 - Monitoring and switching of cortico-basal ganglia loop functions by the thalamo-striatal systemMinoru Kimura
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Neurosci Res 48:355-60. 2004..This model provides a new insight into the function of the CM-Pf complex and should lead to a better understanding of this important brain system... 
Neuronal basis for evaluating selected action in the primate striatumHiroshi Yamada
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Eur J Neurosci 34:489-506. 2011..These activity profiles as a heterogeneous representation of decision variables may underlie a part of the process for reinforcement- and strategy-based evaluation of selected actions in the striatum...- History- and current instruction-based coding of forthcoming behavioral outcomes in the striatumHiroshi Yamada
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
J Neurophysiol 98:3557-67. 2007..The history- and current instruction-based coding of forthcoming behavioral outcomes in the striatum might underlie outcome-oriented behavioral modulation... - Neuronal encoding of reward value and direction of actions in the primate putamenYukiko Hori
Department of Physiology, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
J Neurophysiol 102:3530-43. 2009.... - Tonically active neurons in the primate caudate nucleus and putamen differentially encode instructed motivational outcomes of actionHiroshi Yamada
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
J Neurosci 24:3500-10. 2004..These findings suggest a distinct, pivotal role of TANs in the caudate nucleus and putamen in encoding instructed motivational contexts for goal-directed action planning and learning... 
Dopamine neurons learn to encode the long-term value of multiple future rewardsKazuki Enomoto
Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
Proc Natl Acad Sci U S A 108:15462-7. 2011..These findings demonstrate that dopamine neurons learn to encode the long-term value of multiple future rewards with distant rewards discounted...- Complementary process to response bias in the centromedian nucleus of the thalamusTakafumi Minamimoto
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
Science 308:1798-801. 2005..Electrical stimulation of the CM after a large-reward action request substituted a brisk performance with a sluggish performance. These results suggest involvement of the CM in a mechanism complementary to decision and action bias... - Inactivation of the putamen selectively impairs reward history-based action selectionManabu Muranishi
Department of Neurophysiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Exp Brain Res 209:235-46. 2011..These results support a view that the putamen is involved selectively and critically in neuronal circuits for reward history-based action selection... - Tonically active neurons in the striatum encode motivational contexts of actionMinoru Kimura
Neurophysiology, Graduate School, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 605 8566 Japan
Brain Dev 25:S20-3. 2003..These findings suggest a distinct, pivotal role played by TANs in the caudate nucleus and putamen in encoding instructed motivational contexts for goal-directed action selection and learning in the striatum... - Goal-directed, serial and synchronous activation of neurons in the primate striatumMinoru Kimura
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Neuroreport 14:799-802. 2003..We propose that the task-dependent serial and synchronous activation of striate neurons may be a neural substrate for goal-directed planning through the basal ganglia... - Coding of the long-term value of multiple future rewards in the primate striatumHiroshi Yamada
Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
J Neurophysiol 109:1140-51. 2013..These findings provide a new insight that long-term value signals are embedded in two subsets of striatal neurons as high and low discounting of multiple future rewards... - Thalamic contributions to Basal Ganglia-related behavioral switching and reinforcementYoland Smith
Yerkes National Primate Research Center and Department of Neurology, Emory University, Atlanta, Georgia 30329, USA
J Neurosci 31:16102-6. 2011..We will also address the possibility that degeneration of the thalamostriatal system could underlie some of the deficits in redirection of attention in response to salient stimuli seen in Parkinson's disease... - Roles of the thalamic CM-PF complex-Basal ganglia circuit in externally driven rebias of actionTakafumi Minamimoto
Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
Brain Res Bull 78:75-9. 2009..This model provides a framework for how the thalamic CM-PF complex and the basal ganglia function together in general for unexpected situations... - Correlated coding of motivation and outcome of decision by dopamine neuronsTakemasa Satoh
Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
J Neurosci 23:9913-23. 2003.... - Positron emission tomography: measurement of the activity of second messenger systemsYoshio Imahori
Department of Neurosurgery, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo 602 8566, Kyoto, Japan
Methods 27:251-62. 2002..We report informative findings on postsynaptic biological responses in the living human brain of healthy normal subjects and with various diseases... - Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behaviorKanji Yoshimoto
Department of Forensic Medicine, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
Eur J Neurosci 35:1368-80. 2012..These results suggest that adaptations of the 5-HT system, especially the upregulation of 5-HT(2C) receptors in the ACC(S) , are involved in the development of enhanced voluntary alcohol-drinking behavior... - A neural correlate of reward-based behavioral learning in caudate nucleus: a functional magnetic resonance imaging study of a stochastic decision taskMasahiko Haruno
Computational Neuroscience Laboratories, Advanced Telecommunications Research Institute, Kyoto 619 0288, Japan
J Neurosci 24:1660-5. 2004..These findings suggest that the caudate nucleus is one of the main loci for reward-based behavioral learning... - Encoding of direction and combination of movements by primate putamen neuronsYasumasa Ueda
Faculty of Health and Sport Sciences, Osaka University, Toyonaka, Osaka 560-0043, Japan
Eur J Neurosci 18:980-94. 2003.... - Representation of action-specific reward values in the striatumKazuyuki Samejima
Department of Computational Neurobiology, ATR Computational Neuroscience Laboratories, 619 0288 Kyoto, Japan
Science 310:1337-40. 2005..Fewer neurons were tuned to relative values or action choice. These results suggest representation of action values in the striatum, which can guide action selection in the basal ganglia circuit...