Minoru Kimura

Summary

Affiliation: Kyoto Prefectural University of Medicine
Country: Japan

Publications

  1. ncbi request reprint Participation of the thalamic CM-Pf complex in attentional orienting
    Takafumi Minamimoto
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    J Neurophysiol 87:3090-101. 2002
  2. ncbi request reprint Molecular mechanism of preventive effect of peony root extract on neuron damage
    Katsuyoshi Sunaga
    Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan
    J Herb Pharmacother 4:9-20. 2004
  3. ncbi request reprint What does the habenula tell dopamine neurons?
    Minoru Kimura
    Nat Neurosci 10:677-8. 2007
  4. ncbi request reprint Monitoring and switching of cortico-basal ganglia loop functions by the thalamo-striatal system
    Minoru Kimura
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Neurosci Res 48:355-60. 2004
  5. doi request reprint Neuronal basis for evaluating selected action in the primate striatum
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Eur J Neurosci 34:489-506. 2011
  6. ncbi request reprint History- and current instruction-based coding of forthcoming behavioral outcomes in the striatum
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    J Neurophysiol 98:3557-67. 2007
  7. doi request reprint Coding of the long-term value of multiple future rewards in the primate striatum
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neurophysiol 109:1140-51. 2013
  8. ncbi request reprint Tonically active neurons in the primate caudate nucleus and putamen differentially encode instructed motivational outcomes of action
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Neurosci 24:3500-10. 2004
  9. doi request reprint Neuronal encoding of reward value and direction of actions in the primate putamen
    Yukiko Hori
    Department of Physiology, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
    J Neurophysiol 102:3530-43. 2009
  10. pmc Dopamine neurons learn to encode the long-term value of multiple future rewards
    Kazuki Enomoto
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Proc Natl Acad Sci U S A 108:15462-7. 2011

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Participation of the thalamic CM-Pf complex in attentional orienting
    Takafumi Minamimoto
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    J Neurophysiol 87:3090-101. 2002
    ....
  2. ncbi request reprint Molecular mechanism of preventive effect of peony root extract on neuron damage
    Katsuyoshi Sunaga
    Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan
    J Herb Pharmacother 4:9-20. 2004
    ..These results suggested that an increase in A20 expression is the main molecular mechanism of protective action of peony root extract on neuron damage...
  3. ncbi request reprint What does the habenula tell dopamine neurons?
    Minoru Kimura
    Nat Neurosci 10:677-8. 2007
  4. ncbi request reprint Monitoring and switching of cortico-basal ganglia loop functions by the thalamo-striatal system
    Minoru Kimura
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Neurosci Res 48:355-60. 2004
    ..This model provides a new insight into the function of the CM-Pf complex and should lead to a better understanding of this important brain system...
  5. doi request reprint Neuronal basis for evaluating selected action in the primate striatum
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Eur J Neurosci 34:489-506. 2011
    ..These activity profiles as a heterogeneous representation of decision variables may underlie a part of the process for reinforcement- and strategy-based evaluation of selected actions in the striatum...
  6. ncbi request reprint History- and current instruction-based coding of forthcoming behavioral outcomes in the striatum
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    J Neurophysiol 98:3557-67. 2007
    ..The history- and current instruction-based coding of forthcoming behavioral outcomes in the striatum might underlie outcome-oriented behavioral modulation...
  7. doi request reprint Coding of the long-term value of multiple future rewards in the primate striatum
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neurophysiol 109:1140-51. 2013
    ..These findings provide a new insight that long-term value signals are embedded in two subsets of striatal neurons as high and low discounting of multiple future rewards...
  8. ncbi request reprint Tonically active neurons in the primate caudate nucleus and putamen differentially encode instructed motivational outcomes of action
    Hiroshi Yamada
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Neurosci 24:3500-10. 2004
    ..These findings suggest a distinct, pivotal role of TANs in the caudate nucleus and putamen in encoding instructed motivational contexts for goal-directed action planning and learning...
  9. doi request reprint Neuronal encoding of reward value and direction of actions in the primate putamen
    Yukiko Hori
    Department of Physiology, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto, Japan
    J Neurophysiol 102:3530-43. 2009
    ....
  10. pmc Dopamine neurons learn to encode the long-term value of multiple future rewards
    Kazuki Enomoto
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Proc Natl Acad Sci U S A 108:15462-7. 2011
    ..These findings demonstrate that dopamine neurons learn to encode the long-term value of multiple future rewards with distant rewards discounted...
  11. pmc Inactivation of the putamen selectively impairs reward history-based action selection
    Manabu Muranishi
    Department of Neurophysiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Exp Brain Res 209:235-46. 2011
    ..These results support a view that the putamen is involved selectively and critically in neuronal circuits for reward history-based action selection...
  12. ncbi request reprint Complementary process to response bias in the centromedian nucleus of the thalamus
    Takafumi Minamimoto
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Science 308:1798-801. 2005
    ..Electrical stimulation of the CM after a large-reward action request substituted a brisk performance with a sluggish performance. These results suggest involvement of the CM in a mechanism complementary to decision and action bias...
  13. ncbi request reprint Tonically active neurons in the striatum encode motivational contexts of action
    Minoru Kimura
    Neurophysiology, Graduate School, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 605 8566 Japan
    Brain Dev 25:S20-3. 2003
    ..These findings suggest a distinct, pivotal role played by TANs in the caudate nucleus and putamen in encoding instructed motivational contexts for goal-directed action selection and learning in the striatum...
  14. ncbi request reprint Goal-directed, serial and synchronous activation of neurons in the primate striatum
    Minoru Kimura
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Neuroreport 14:799-802. 2003
    ..We propose that the task-dependent serial and synchronous activation of striate neurons may be a neural substrate for goal-directed planning through the basal ganglia...
  15. pmc Thalamic contributions to Basal Ganglia-related behavioral switching and reinforcement
    Yoland Smith
    Yerkes National Primate Research Center and Department of Neurology, Emory University, Atlanta, Georgia 30329, USA
    J Neurosci 31:16102-6. 2011
    ..We will also address the possibility that degeneration of the thalamostriatal system could underlie some of the deficits in redirection of attention in response to salient stimuli seen in Parkinson's disease...
  16. doi request reprint Roles of the thalamic CM-PF complex-Basal ganglia circuit in externally driven rebias of action
    Takafumi Minamimoto
    Department of Physiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Brain Res Bull 78:75-9. 2009
    ..This model provides a framework for how the thalamic CM-PF complex and the basal ganglia function together in general for unexpected situations...
  17. ncbi request reprint Correlated coding of motivation and outcome of decision by dopamine neurons
    Takemasa Satoh
    Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Neurosci 23:9913-23. 2003
    ....
  18. ncbi request reprint Positron emission tomography: measurement of the activity of second messenger systems
    Yoshio Imahori
    Department of Neurosurgery, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo 602 8566, Kyoto, Japan
    Methods 27:251-62. 2002
    ..We report informative findings on postsynaptic biological responses in the living human brain of healthy normal subjects and with various diseases...
  19. pmc Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior
    Kanji Yoshimoto
    Department of Forensic Medicine, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Eur J Neurosci 35:1368-80. 2012
    ..These results suggest that adaptations of the 5-HT system, especially the upregulation of 5-HT(2C) receptors in the ACC(S) , are involved in the development of enhanced voluntary alcohol-drinking behavior...
  20. ncbi request reprint A neural correlate of reward-based behavioral learning in caudate nucleus: a functional magnetic resonance imaging study of a stochastic decision task
    Masahiko Haruno
    Computational Neuroscience Laboratories, Advanced Telecommunications Research Institute, Kyoto 619 0288, Japan
    J Neurosci 24:1660-5. 2004
    ..These findings suggest that the caudate nucleus is one of the main loci for reward-based behavioral learning...
  21. ncbi request reprint Encoding of direction and combination of movements by primate putamen neurons
    Yasumasa Ueda
    Faculty of Health and Sport Sciences, Osaka University, Toyonaka, Osaka 560 0043, Japan
    Eur J Neurosci 18:980-94. 2003
    ....
  22. ncbi request reprint Representation of action-specific reward values in the striatum
    Kazuyuki Samejima
    Department of Computational Neurobiology, ATR Computational Neuroscience Laboratories, 619 0288 Kyoto, Japan
    Science 310:1337-40. 2005
    ..Fewer neurons were tuned to relative values or action choice. These results suggest representation of action values in the striatum, which can guide action selection in the basal ganglia circuit...