Mitsuhiro Kawata

Summary

Affiliation: Kyoto Prefectural University of Medicine
Country: Japan

Publications

  1. doi request reprint Endogenous glucocorticoids improve myelination via Schwann cells after peripheral nerve injury: An in vivo study using a crush injury model
    Shinsuke Morisaki
    Department of Orthopedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Glia 58:954-63. 2010
  2. doi request reprint Steroid receptor signalling in the brain--lessons learned from molecular imaging
    M Kawata
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    J Neuroendocrinol 20:673-6. 2008
  3. doi request reprint Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 215:837-45. 2008
  4. doi request reprint Expression of G protein-coupled receptor 30 in the spinal somatosensory system
    Keiko Takanami
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Brain Res 1310:17-28. 2010
  5. ncbi request reprint Imaging analysis of mineralocorticoid receptor and importins in single living cells by using GFP color variants
    Masayuki Tanaka
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Cell Tissue Res 320:447-53. 2005
  6. pmc Androgen regulates the sexually dimorphic gastrin-releasing peptide system in the lumbar spinal cord that mediates male sexual function
    Hirotaka Sakamoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Endocrinology 150:3672-9. 2009
  7. doi request reprint In vivo effects of ovarian steroid hormones on the expressions of estrogen receptors and the composition of extracellular matrix in the anterior cruciate ligament in rats
    Atsuhiko Yoshida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Connect Tissue Res 50:121-31. 2009
  8. ncbi request reprint GFP chimeric models exhibited a biphasic pattern of mesenchymal cell invasion in tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 210:684-91. 2007
  9. doi request reprint Bone marrow-derived cells from the footprint infiltrate into the repaired rotator cuff
    Yoshikazu Kida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Shoulder Elbow Surg 22:197-205. 2013
  10. ncbi request reprint Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus
    Fang Han
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Neurosci Res 51:371-81. 2005

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. doi request reprint Endogenous glucocorticoids improve myelination via Schwann cells after peripheral nerve injury: An in vivo study using a crush injury model
    Shinsuke Morisaki
    Department of Orthopedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Glia 58:954-63. 2010
    ..These results suggest that endogenous glucocorticoids have an important role in myelination through the GR in Schwann cells after an in vivo peripheral nerve injury...
  2. doi request reprint Steroid receptor signalling in the brain--lessons learned from molecular imaging
    M Kawata
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    J Neuroendocrinol 20:673-6. 2008
    ..Genomic as well as non-genomic actions of steroid hormones influence the cellular function of target tissues spacio-temporally...
  3. doi request reprint Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 215:837-45. 2008
    ..These findings suggest that locally injected PRP is useful as an activator of circulation-derived cells for enhancement of the initial tendon healing process...
  4. doi request reprint Expression of G protein-coupled receptor 30 in the spinal somatosensory system
    Keiko Takanami
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Brain Res 1310:17-28. 2010
    ..GPR30 expression was downregulated in DRG neurons of ovariectomized female rats. The spinal somatosensory system might be modulated by estradiol via putative membrane ER, GPR30-mediated mechanism...
  5. ncbi request reprint Imaging analysis of mineralocorticoid receptor and importins in single living cells by using GFP color variants
    Masayuki Tanaka
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    Cell Tissue Res 320:447-53. 2005
    ..This is the first visual evidence of the nuclear import of MR in association with importin alpha in single living cells...
  6. pmc Androgen regulates the sexually dimorphic gastrin-releasing peptide system in the lumbar spinal cord that mediates male sexual function
    Hirotaka Sakamoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Endocrinology 150:3672-9. 2009
    ..A greater understanding of how androgen modulates the spinal GRP system might lead to new therapeutic approaches to male sexual dysfunction...
  7. doi request reprint In vivo effects of ovarian steroid hormones on the expressions of estrogen receptors and the composition of extracellular matrix in the anterior cruciate ligament in rats
    Atsuhiko Yoshida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Connect Tissue Res 50:121-31. 2009
    ..These findings suggest that ACL is ER-dependent and that ovarian hormones alter ligament tissue composition, especially at the proximal portion. Female hormonal influences are partly involved in the biological properties of ACL...
  8. ncbi request reprint GFP chimeric models exhibited a biphasic pattern of mesenchymal cell invasion in tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 210:684-91. 2007
    ..These findings suggest that circulation-derived and tendon-derived cells contribute to the healing of tendons in different periods as part of a biphasic process...
  9. doi request reprint Bone marrow-derived cells from the footprint infiltrate into the repaired rotator cuff
    Yoshikazu Kida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Shoulder Elbow Surg 22:197-205. 2013
    ..Cells from the bone marrow are considered important during the rotator cuff repair process, but the kinetics of bone marrow-derived cells in this process is unknown...
  10. ncbi request reprint Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus
    Fang Han
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Neurosci Res 51:371-81. 2005
    ..These results suggest that the balance of MR and GR in the cell underlies the potential regulation of corticosteroid through the hippocampus and hypothalamus...
  11. pmc Characterization of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems
    Natsuko Kaku
    Departments of Anatomy and Neurobiology, Research Institute for Geriatric and Neurobiological Diseases, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Endocrinology 149:3960-9. 2008
    ..Our data suggest that the nuclear import of AR is regulated by the interplay between each domain of the AR...
  12. doi request reprint Immunohistochemical analysis of the effects of estrogen on intraarticular neurogenic inflammation in a rat anterior cruciate ligament transection model of osteoarthritis
    Atsuhiko Yoshida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
    Connect Tissue Res 53:197-206. 2012
    ..These findings suggest that estrogen partly regulates intraarticular neurogenic inflammation in OA joints by modulating the expressions of neuropeptides in the synovium...
  13. ncbi request reprint Imaging analysis of subcellular correlation of androgen receptor and estrogen receptor alpha in single living cells using green fluorescent protein color variants
    Ikuo Ochiai
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Mol Endocrinol 18:26-42. 2004
    ..Taken together, using an imaging technique, we clarified that possible homo/hetero dimerization between AR and ERalpha could be attributed to androgen-estrogen interaction in living cells...
  14. pmc Stress affects a gastrin-releasing peptide system in the spinal cord that mediates sexual function: implications for psychogenic erectile dysfunction
    Hirotaka Sakamoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    PLoS ONE 4:e4276. 2009
    ..Recently, we identified a gastrin-releasing peptide (GRP) system in the lumbar spinal cord that is a primary mediator for male reproductive functions...
  15. ncbi request reprint Visualization of glucocorticoid receptor and mineralocorticoid receptor interactions in living cells with GFP-based fluorescence resonance energy transfer
    Mayumi Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    J Neurosci 24:4918-27. 2004
    ..These results obtained with FRET analyses give new insights into the sites, time course, and effects of ligand concentration on heterodimersization of the GR and MR...
  16. ncbi request reprint A differential ligand-mediated response of green fluorescent protein-tagged androgen receptor in living prostate cancer and non-prostate cancer cell lines
    Hiroo Nakauchi
    Department of Urology, Kyoto Prefectural University of Medicine, Kamigyo ku, Kyoto 602 8566, Japan
    J Histochem Cytochem 55:535-44. 2007
    ....
  17. doi request reprint Positive effect on bone fusion by the combination of platelet-rich plasma and a gelatin β-tricalcium phosphate sponge: a study using a posterolateral fusion model of lumbar vertebrae in rats
    Shin ichi Okamoto
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Tissue Eng Part A 18:157-66. 2012
    ..These results indicate that the PRP sponge could, therefore, be potentially useful as an attractive and less invasive method for bone fusion...
  18. doi request reprint Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation
    Kenichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    Neurosci Lett 441:94-9. 2008
    ..Expression levels were not different among male, female in proestrus and female in estrus at the adult stage, but were higher in newborn male than newborn female...
  19. doi request reprint Characteristics of donor and host cells in the early remodeling process after transplant of Achilles tendon with and without live cells for the treatment of rotator cuff defect--what is the ideal graft for the treatment of massive rotator cuff defects?
    Hisakazu Tachiiri
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Shoulder Elbow Surg 19:891-8. 2010
    ..We also clarified which graft with or without live cells was superior in the early remodeling process...
  20. ncbi request reprint Behavior of host and graft cells in the early remodeling process of rotator cuff defects in a transgenic animal model
    Yoshio Iwata
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Shoulder Elbow Surg 17:101S-107S. 2008
    ..The number of graft-derived cells decreased with time. Our result clearly demonstrated that host cells, rather than graft cells, were essential for rotator cuff remodeling after tendon grafting for rotator cuff defect...
  21. ncbi request reprint Application of Raman spectroscopy for visualizing biochemical changes during peripheral nerve injury in vitro and in vivo
    Shinsuke Morisaki
    Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Orthopaedics, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Biomed Opt 18:116011. 2013
    ..Thus, our results suggest that label-free biochemical imaging with Raman spectroscopy can be used to detect turnover of axon and myelin in peripheral nerve regeneration...
  22. doi request reprint Epigenetic mechanisms are involved in sexual differentiation of the brain
    Ken ichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Rev Endocr Metab Disord 13:163-71. 2012
    ..Taken together, these results suggest that epigenetic mechanisms play a central role in the transduction and maintenance of early hormonal and social cues to organize sexually differentiated brain functions...
  23. doi request reprint Characterization of in vivo effects of platelet-rich plasma and biodegradable gelatin hydrogel microspheres on degenerated intervertebral discs
    Kazuhide Sawamura
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Tissue Eng Part A 15:3719-27. 2009
    ..These results provide an improved understanding of the therapeutic effects of PRP-GHM treatment of degenerated IVDs...
  24. ncbi request reprint Yellow fluorescent protein-tagged and cyan fluorescent protein-tagged imaging analysis of glucocorticoid receptor and importins in single living cells
    Masayuki Tanaka
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Endocrinology 144:4070-9. 2003
    ..However, direct interaction between GR and importin-beta was not detected. These studies showed visual evidence of the nuclear importing of GR in association with importin-alpha in single living cells...
  25. ncbi request reprint Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei
    Hirotaka Sakamoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Endocrinology 148:5842-50. 2007
    ..In addition, the expression of GPR30 is also detected in the neurohypophysis. These results suggest that GPR30 may serve primarily as a nongenomic transducer of estrogen actions in the hypothalamo-neurohypophyseal system...
  26. pmc Histone deacetylation during brain development is essential for permanent masculinization of sexual behavior
    Ken ichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Endocrinology 152:2760-7. 2011
    ..These results demonstrate that HDAC activity during the early postnatal period plays a crucial role in the masculinization of the brain via modifications of histone acetylation status...
  27. ncbi request reprint Behavior of transplanted bone marrow-derived GFP mesenchymal cells in osteochondral defect as a simulation of autologous transplantation
    Yasushi Oshima
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Histochem Cytochem 53:207-16. 2005
    ....
  28. ncbi request reprint The fate of host and graft cells in early healing of bone tunnel after tendon graft
    Masashi Kobayashi
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Am J Sports Med 33:1892-7. 2005
    ..The behavior of host and graft cells during the healing process after autologous tendon graft has not been elucidated...
  29. ncbi request reprint Intranuclear mobility of estrogen receptor alpha and progesterone receptors in association with nuclear matrix dynamics
    Kenichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Cell Biochem 103:136-48. 2008
    ..These results indicate that the mobility of ER alpha and PR-A/B is associated with the dynamics of the nuclear matrix...
  30. doi request reprint Visualisation and characterisation of oestrogen receptor α-positive neurons expressing green fluorescent protein under the control of the oestrogen receptor α promoter
    Ken ichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, 465 Kawaramachi Hirokoji, Kamigyoku, Kyoto 602 8566, Japan
    Eur J Neurosci 38:2242-9. 2013
    ..Thus, the ERα promoter-GFP tg mice will be useful to analyse the development and plastic changes of the structure of ERα-expressing neurons and oestrogen and its receptor-mediated neuronal responses...
  31. pmc A recently identified hypothalamic nucleus expressing estrogen receptor alpha
    Hiroko Mori
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Proc Natl Acad Sci U S A 105:13632-7. 2008
    ..This unique hypothalamic nucleus with its morphological sex differences and hormonal responsiveness is embedded in a region important for the regulation of endocrine functions and sexual behaviors...
  32. ncbi request reprint Effects of estrogens on cholinergic neurons in the rat basal nucleus
    Hiroki Yamamoto
    Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kamigyo ku, Kyoto 602 8566, Japan
    J Steroid Biochem Mol Biol 107:70-9. 2007
    ..These results suggest that E(2) and J 861 have positive effects on cholinergic neurons that project from the basal nucleus to the forebrain cortex...
  33. ncbi request reprint Serotonergic neurones in the dorsal raphe nucleus that project into the medial preoptic area contain oestrogen receptor beta
    H Lu
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan
    J Neuroendocrinol 13:839-45. 2001
    ....
  34. doi request reprint The fate and role of bone graft-derived cells after autologous tendon and bone transplantation into the bone tunnel
    Hiroto Komiyama
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    J Orthop Sci 18:994-1004. 2013
    ..The purpose of this research was to elucidate the role of bone graft cells after autologous tendon graft into the bone tunnel with an autologous bone graft in green fluorescent protein (GFP) transgenic rats...
  35. ncbi request reprint Appearance of LFA-1 in the initial stage of synaptogenesis of developing hippocampal neurons
    Yoshihiro Wakabayashi
    Department of Transplantation and Regenerative Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Arch Histol Cytol 71:23-36. 2008
    ..These results suggest that LFA-1 plays some mechanisms in synaptic contacts and synaptogenesis of hippocampal neurons...
  36. pmc Sexually dimorphic gastrin releasing peptide system in the spinal cord controls male reproductive functions
    Hirotaka Sakamoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Nat Neurosci 11:634-6. 2008
    ..GRP offers new avenues for understanding potential therapeutic approaches to masculine reproductive dysfunction...
  37. doi request reprint Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα
    Takashi Hashimoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Cell Biochem 113:3039-50. 2012
    ..These results indicate that SAFB1 and SAFB2 are crucial repressors for ERα dynamics in association with the nuclear matrix and that their synergistic regulation of ERα mobility is sufficient for inhibiting ERα function...
  38. ncbi request reprint Brain corticosteroid receptor dynamics and trafficking: Implications from live cell imaging
    Mayumi Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Neuroscientist 12:119-33. 2006
    ..In this review, the authors focus on the nucleocytoplasmic and subnuclear trafficking of GR and MR in neural cells and nonneural cells and discuss various factors affecting the dynamics of these receptors...
  39. ncbi request reprint Dynamics of glucocorticoid receptor and mineralocorticoid receptor: implications from live cell imaging studies
    Mayumi Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Neuroendocrinology 85:186-92. 2007
    ..In the nuclear region, we detected GR-MR heterodimers, which were affected by changes in CORT concentrations in response to various hormonal milieus such as circadian rhythm and stress...
  40. ncbi request reprint Visualization of glucocorticoid receptor in the brain of green fluorescent protein-glucocorticoid receptor knockin mice
    T Usuku
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    Neuroscience 135:1119-28. 2005
    ..This is the first report visualizing subcellular trafficking of the GR in the mouse brain in more physiological condition. The present results propose new avenues for the research of the GR dynamics both in vitro and in vivo...
  41. doi request reprint G protein-coupled receptor 30 contributes to improved remyelination after cuprizone-induced demyelination
    Yukie Hirahara
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Japan
    Glia 61:420-31. 2013
    ..This study is the first evidence that GPR30 signaling promotes remyelination by oligodendrocytes after demyelination. GPR30 ligands may provide a novel therapy for the treatment of multiple sclerosis...
  42. doi request reprint Androgen action in the brain and spinal cord for the regulation of male sexual behaviors
    Ken ichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    Curr Opin Pharmacol 8:747-51. 2008
    ..Elucidation of the molecular mechanism along with the neuroanatomical background should guide the development of novel pharmacotherapeutics for sexual behavior dysfunction...
  43. doi request reprint In vivo assessment of peripheral nerve regeneration by diffusion tensor imaging
    Shinsuke Morisaki
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
    J Magn Reson Imaging 33:535-42. 2011
    ..We assessed the changes in the DTI parameters and histological analyses after nerve injury to examine degeneration and regeneration in the rat sciatic nerves...
  44. ncbi request reprint Estrogen reduces the neurite growth of serotonergic cells expressing estrogen receptors
    Haiping Lu
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Neurosci Res 50:23-8. 2004
    ..Our results suggest that the inhibitory effects of E2 on the neurite growth of serotonergic cells expressing ERalpha or ERbeta might be involved in the formation of the sexual dimorphic distribution of serotonergic innervation...
  45. ncbi request reprint Selective visualization of rabbit knee cartilage using MR imaging with a double-contrast agent
    Masamitsu Kido
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Magn Reson Imaging 39:1186-90. 2014
    ..To establish a reliable method and efficient contrast agent for selective MR imaging of articular cartilage to improve the diagnosis of cartilage disorders...
  46. ncbi request reprint Distribution of gastrin-releasing peptide in the rat trigeminal and spinal somatosensory systems
    Keiko Takanami
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566, Japan
    J Comp Neurol 522:1858-73. 2014
    ..These results suggest that GRP-dependent orofacial and spinal pruriceptive inputs are processed mainly in the superficial laminae of the Vc and spinal dorsal horn...
  47. ncbi request reprint Sonoporation mediated transduction of pDNA/siRNA into joint synovium in vivo
    Masazumi Saito
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Orthop Res 25:1308-16. 2007
    ..In this study, we showed that pDNA/siRNA can be transduced specifically into the joint synovium using sonoporation. The present method may be useful in nucleic acid therapy for joint disorders...
  48. ncbi request reprint Intervertebral disc regeneration using platelet-rich plasma and biodegradable gelatin hydrogel microspheres
    Masateru Nagae
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Tissue Eng 13:147-58. 2007
    ..Our results suggest that the combined administration of PRP and gelatin hydrogel microspheres into the IVD may be a promising therapeutic modality for IVD degeneration...
  49. doi request reprint Intrauterine position affects estrogen receptor α expression in the ventromedial nucleus of the hypothalamus via promoter DNA methylation
    Hiroko Mori
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Endocrinology 151:5775-81. 2010
    ..This suggests that genomic methylation sustains the effect of the fetal IUP on ERα expression in the vlVMH...
  50. doi request reprint Expression, localization and possible actions of 25-Dx, a membraneassociated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: a new insight into the biosynthesis, metabolism and multiple actions of progesterone as
    Hirotaka Sakamoto
    Laboratory of Brain Science, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi Hiroshima, Japan
    Cerebellum 7:18-25. 2008
    ..Here we summarize the advances made in our understanding of the expression, localization and its possible actions of 25-Dx in the developing Purkinje cell...
  51. ncbi request reprint Introduction for "donor transplant vs. recipient cells in musculoskeletal system"
    Nobuyoshi Watanabe
    Department of Orthopaedic Surgery, Kyoto Prefectual University of Medicine, Kyoto, 602 8566, Japan
    Microsc Res Tech 58:1-2. 2002
  52. ncbi request reprint Localization of nuclear coactivators p300 and steroid receptor coactivator 1 in the rat hippocampus
    H Ogawa
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, 465 Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Brain Res 890:197-202. 2001
    ..These findings suggest that in the hippocampus p300 and SRC-1 synergistically play an important role in activating ligand-dependent transcription by steroid hormone receptor...
  53. ncbi request reprint Real-time imaging of glucocorticoid receptor dynamics in living neurons and glial cells in comparison with non-neural cells
    M Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Eur J Neurosci 11:1927-36. 1999
    ....
  54. ncbi request reprint Trophic interactions between brain-derived neurotrophic factor and s100beta on cultured serotonergic neurons
    M Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, 602 8566, Kyoto, Japan
    Brain Res 868:113-8. 2000
    ..Our results suggest that BDNF and S100beta, which regulate different signal transduction cascades, interact to exert complimentary effects on neuronal maturation by acting sequentially, not concurrently...
  55. doi request reprint Gastrin-releasing peptide system in the spinal cord controls male sexual behaviour
    H Sakamoto
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neuroendocrinol 21:432-5. 2009
    ....
  56. ncbi request reprint Cellular localization and distribution of glucocorticoid receptor immunoreactivity and the expression of glucocorticoid receptor messenger RNA in rat pituitary gland. A combined double immunohistochemistry study and in situ hybridization histochemical ana
    H Ozawa
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Cell Tissue Res 295:207-14. 1999
    ..These results suggest that glucocorticoids directly influence certain pituitary cells in order to regulate cell function, including the synthesis and/or secretion of hormones...
  57. ncbi request reprint Steroid hormones and their receptors in the brain
    M Kawata
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Japan
    J Steroid Biochem Mol Biol 65:273-80. 1998
    ..These results suggest that steroids modulate the gene expression along with the alteration of cell structures in a different manner in a tissue-specific pattern...
  58. ncbi request reprint Adrenalectomy-induced granule cell death is predicated on the disappearance of glucocorticoid receptor immunoreactivity in the rat hippocampal granule cell layer
    Z Hu
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Japan
    Brain Res 778:293-301. 1997
    ....
  59. ncbi request reprint S100beta promotes the extension of microtubule associated protein2 (MAP2)-immunoreactive neurites retracted after colchicine treatment in rat spinal cord culture
    M Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kamigyou ku, Japan
    Neurosci Lett 229:212-4. 1997
    ..These results indicate that neurites shrink when the microtubular cytoskeletal system is disrupted and S100beta rapidly promotes re-assembly and/or stabilization...
  60. ncbi request reprint The distributions of apoptotic cells in the medial preoptic areas of male and female neonatal rats
    M Yoshida
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Japan
    Neurosci Res 36:1-7. 2000
    ..In P14 rats, very few apoptotic cells were seen in the MPA. Our data revealed that the distribution of apoptotic cells in the MPA of developing rats depends on the sexuality, subdivision of the area and postnatal period...
  61. ncbi request reprint Dynamic changes in subcellular localization of mineralocorticoid receptor in living cells: in comparison with glucocorticoid receptor using dual-color labeling with green fluorescent protein spectral variants
    M Nishi
    Department of Anatomy and Neurobiology Kyoto Prefectural University of Medicine Kawaramachi Hirokoji, Kamigyo ku Kyoto 602 8566, Japan
    Mol Endocrinol 15:1077-92. 2001
    ..These results suggest that CORT-induced nuclear translocation of MR and GR exhibits differential patterns depending on ligand concentrations or cell types...
  62. ncbi request reprint Intracellular dynamics of steroid hormone receptor
    M Kawata
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Neurosci Res 40:197-203. 2001
    ..This paper describes some of the recent investigations into the subcellular localization of steroid hormone receptors and cofactors using GFPs and other immunocytochemical methods...
  63. ncbi request reprint Left ventricular apex venting during deep hypothermia in a case of difficult re-entry into the mediastinum
    K Ito
    Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Cardiovasc Surg (Torino) 42:493-4. 2001
    ..We found that this technique was easy, safe, and useful to prevent ventricular distention during cooling...
  64. ncbi request reprint Immunohistochemical studies on the distribution of nerve fibers in the human prostate with special reference to the anterior fibromuscular stroma
    T Iwata
    Department of Urology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    Prostate 48:242-7. 2001
    ..We recently reported the possible contribution of the AFMS to micturition. The aim of this study is to reveal the differences in the distribution of innervation between the AFMS and the other regions of the prostate...
  65. ncbi request reprint Subcellular steroid/nuclear receptor dynamics
    M Kawata
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Japan
    Arch Histol Cytol 64:353-68. 2001
    ..This focal organization could involve more complex events than simple DNA binding sites for transcription. Protein activities and interactions of steroid/nuclear receptors can be imaged and localized in a single cell...
  66. ncbi request reprint Annexin-1 (lipocortin-1)-immunoreactivity in the folliculo-stellate cells of rat anterior pituitary: the effect of adrenalectomy and corticosterone treatment on its subcellular distribution
    H Ozawa
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neuroendocrinol 14:621-8. 2002
    ..These results confirm that glucocorticoids regulate the annexin-1 expression and demonstrate the translocation of annexin-1 from intracellular to pericellular sites in the FS cells of the rat anterior pituitary gland...
  67. ncbi request reprint Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy
    F Han
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neuroendocrinol 19:229-38. 2007
    ....
  68. ncbi request reprint Direct visualization of glucocorticoid receptor positive cells in the hippocampal regions using green fluorescent protein transgenic mice
    M Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Neuroscience 146:1555-60. 2007
    ..These results indicate that this transgenic mouse line should be useful for live imaging of neuronal structure in animals as well as GR-positive cultured cells using GFP as a specific indicator...
  69. ncbi request reprint [Membrane-associated steroid hormone receptors: functional significance of nongenomic action]
    Mitsuhiro Kawata
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine
    Nihon Rinsho 66:55-62. 2008
    ..Rapid nongenomic actions of steroids provide new insight for the understanding of steroid effects on the various system of the body...
  70. ncbi request reprint Fate of transplanted bone-marrow-derived mesenchymal cells during osteochondral repair using transgenic rats to simulate autologous transplantation
    Yasushi Oshima
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 602 8566 Japan
    Osteoarthritis Cartilage 12:811-7. 2004
    ..With this aim in view, the survival of transplanted bone-marrow-derived mesenchymal cells within osteochondral defects was determined using transgenic rats to simulate autologous transplantation...
  71. doi request reprint Nurture: effects of intrauterine position on behaviour
    Mitsuhiro Kawata
    Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neuroendocrinol 25:422-3. 2013
    ..The intrauterine environment may also account for the variability of laboratory animals and newborn human twins...
  72. ncbi request reprint Real-time imaging of green fluorescent protein-tagged beta 2-adrenergic receptor distribution in living cells
    Masataka Sunaguchi
    Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, 602 8566, Kyoto, Japan
    Brain Res 984:21-32. 2003
    ..Our results demonstrate spatial and temporal redistribution pattern of beta(2)AR in living non-neuronal cells and neuronal cells...
  73. ncbi request reprint Intrauterine proximity to male fetuses affects the morphology of the sexually dimorphic nucleus of the preoptic area in the adult rat brain
    Minjuan Pei
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    Eur J Neurosci 23:1234-40. 2006
    ..The results suggested that there was a relationship between the fetal intrauterine position, hormone transfer from adjacent fetuses and the SDN-POA volume in adult rat brains...
  74. ncbi request reprint Estrogen and non-feminizing estrogen for Alzheimer's disease
    Hideo Honjo
    Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Endocr J 50:361-7. 2003
    ..Also, J 861 suppressed the expression of adhesive factors, such as E-selectin and intercellular cell adhesion molecule-1 (ICAM-1), more effectively than E2...
  75. ncbi request reprint Effects of gonadectomy on immunoreactivity for choline acetyltransferase in the cortex, hippocampus, and basal forebrain of adult male rats
    N Nakamura
    Department of Anatomy and Neurobiology, Kyoto Perfectural University of Medicine, Kyoto, Japan
    Neuroscience 109:473-85. 2002
    ..Our observations demonstrate that the presence or absence of testosterone for 4 weeks influenced the cholinergic population region-specifically in the adult rat brain...
  76. doi request reprint Effects of single-prolonged stress on neurons and their afferent inputs in the amygdala
    H Cui
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Neuroscience 152:703-12. 2008
    ....
  77. ncbi request reprint The effects of NGF and glucocorticoid on the cytological features of rat chromaffin cells in vitro
    M Morimoto
    Department of Anatomy, Kyoto Prefectural University of Medicine, Japan
    Neuroreport 5:954-6. 1994
    ..These results suggest that as development proceeds locally-derived factors become less potent on chromaffin cell differentiation...
  78. doi request reprint The single-prolonged stress paradigm alters both the morphology and stress response of magnocellular vasopressin neurons
    T Yoshii
    Department of Psychiatry, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Neuroscience 156:466-74. 2008
    ..These findings suggest that AVP is a potential biomarker for past exposure to severe stress and that alterations in AVP may affect the development of pathogenesis in stress-related disorders...
  79. pmc Estrogenic regulation of histamine receptor subtype h1 expression in the ventromedial nucleus of the hypothalamus in female rats
    Hiroko Mori
    Department of Medical Education, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    PLoS ONE 9:e96232. 2014
    ..This enhancement of histamine signaling might be functionally important for allowing neural excitation in response to estrogen stimulation of the neural circuit and may serve as an accelerator of female sexual arousal. ..
  80. doi request reprint Testosterone has sublayer-specific effects on dendritic spine maturation mediated by BDNF and PSD-95 in pyramidal neurons in the hippocampus CA1 area
    Meihua Li
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Brain Res 1484:76-84. 2012
    ..These findings reveal a novel role of testosterone in prevented the differential response properties of spine maturation in sublayers of dendritic spines in the CA1 area via the actions of BDNF and PSD-95...
  81. ncbi request reprint Electro-transfer of small interfering RNA ameliorated arthritis in rats
    Atsuo Inoue
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Biochem Biophys Res Commun 336:903-8. 2005
    ..Our results suggest the potential feasibility of therapeutic intervention with RNA medicines for treatment of rheumatoid and other locomotor diseases...
  82. ncbi request reprint Colocalization and ligand-dependent discrete distribution of the estrogen receptor (ER)alpha and ERbeta
    Ken ichi Matsuda
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Mol Endocrinol 16:2215-30. 2002
    ....
  83. pmc Keratinocyte growth inhibition through the modification of Wnt signaling by androgen in balding dermal papilla cells
    Tomoko Kitagawa
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokouji, Kyoto, Japan
    J Clin Endocrinol Metab 94:1288-94. 2009
    ..We hypothesized that androgen reduces hair growth via an interaction with the Wnt signaling system. The objective of this study was to investigate the effect of androgen on Wnt signaling in dermal papilla (DP) cells...
  84. ncbi request reprint Exocytosis sensitivity to growth hormone-releasing hormone in subsets of GH cells in rats under different corticosterone conditions. Ultrastructural study using microwave irradiation for fixation and immunocytochemistry
    Hitoshi Ozawa
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Endocrinol 183:507-15. 2004
    ..These results suggest that the secretion of GH stimulated by GRH is closely related to corticosteroids, and that the sensitivity to GRH differs among the three subtypes of GH cells...
  85. ncbi request reprint Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner
    M Nishi
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Neurosci 21:RC185. 2001
    ..Our results indicate that NR3B is important as a regulatory subunit that controls NMDA receptor transmission in motoneurons. It may be involved in the pathogenesis of neurodegenerative diseases involving motoneurons as well...
  86. ncbi request reprint Changes in serotonergic neurons in the brain of pyrithiamine-induced acute thiamine-deficient mice
    H Matsushita
    Department of Pediatrics, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Acta Neuropathol 98:614-21. 1999
    ..This is the first report to demonstrate changes in 5-HT neurons immunohistochemically throughout the brain of pyrithiamine-induced thiamine deficient mouse...
  87. doi request reprint Sagittalis nucleus: a novel hypothalamic nucleus
    H Mori
    Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Neuroendocrinol 21:406-9. 2009
    ..The discovery of the SGN, a target of sex steroid action, provides a new opportunity for explaining hormonal regulation of sexually-differentiated behavioural and endocrine functions...
  88. ncbi request reprint Progestins and estrogens and Alzheimer's disease
    Hideo Honjo
    Department of Gynecology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi, Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Steroid Biochem Mol Biol 93:305-8. 2005
    ..like E2. More investigations about progestins and estrogens and AD should be done...
  89. ncbi request reprint A method of tracking donor cells after simulated autologous transplantation: a study using synovial cells of transgenic rats
    N Watanabe
    Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Japan
    Cell Tissue Res 298:519-25. 1999
    ....
  90. ncbi request reprint Behavior of graft and host cells in underlying subchondral bone after transplantation of osteochondral autograft
    Yasushi Oshima
    Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Microsc Res Tech 58:19-24. 2002
    ..The two models of the transplantations using the transgenic rats were found to be beneficial in following graft cells as well as host cells and in understanding their function on healing after autologous transplantation...
  91. ncbi request reprint Localization and regulation of mRNAs in the nervous tissue as revealed by in situ hybridization
    M Kawata
    Department of Anatomy, Kyoto Prefectural University of Medicine, Japan
    Comp Biochem Physiol C 98:41-50. 1991
    ..3. This review will focus on the localization and regulation of different mRNAs in the nervous system from Drosophila to human, as revealed by in situ hybridization histochemistry...
  92. doi request reprint Regional distribution of importin subtype mRNA expression in the nervous system: study of early postnatal and adult mouse
    K Hosokawa
    Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, 602 8566 Japan
    Neuroscience 157:864-77. 2008
    ..This is the first report of importin-alphas and beta1 expression throughout the CNS of adult mice, as well as in the developing brain, including cell type specific localization...
  93. ncbi request reprint Neuro-glial neurotrophic interaction in the S-100 beta retarded mutant mouse (Polydactyly Nagoya). III. Transplantation study
    S Ueda
    Department of Histology and Neurobiology, Dokkyo University School of Medicine, Tochigi, Japan
    Brain Res 738:15-23. 1996
    ..The present results suggest that the expression of S-100 beta in the astrocytes of early stage of transplantation is a critical for fiber ingrowth of serotonergic neurons and expressions of 5-HT1A receptor...
  94. ncbi request reprint Steroid effects on secretion from subsets of lactotrophs: role of folliculo-stellate cells and annexin 1
    J F Morris
    Department of Human Anatomy and Genetics, University of Oxford, UK
    Arch Physiol Biochem 110:54-61. 2002
    ....
  95. ncbi request reprint Physiological studies of stress responses in the hypothalamus of vasopressin-enhanced green fluorescent protein transgenic rat
    M Shibata
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Neuroendocrinol 19:285-92. 2007
    ..p. administration of LPS. Our results indicate that AVP-eGFP transgenic rats are useful animal model to study dynamic changes of AVP expression in the hypothalamus under stressful conditions...
  96. doi request reprint Specific expression of optically active reporter gene in arginine vasopressin-secreting neurosecretory cells in the hypothalamic-neurohypophyseal system
    Y Ueta
    Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Neuroendocrinol 20:660-4. 2008
    ....
  97. ncbi request reprint The posttranslationally modified C-terminal structure of bovine aortic smooth muscle rhoA p21
    M Katayama
    Department of Biochemistry, Kobe University School of Medicine, Japan
    J Biol Chem 266:12639-45. 1991
    ..These results suggest that rhoA p21 is first geranylgeranylated followed by removal of the three C-terminal amino acids and the subsequent carboxyl methylation of the exposed cysteine residue...
  98. pmc Cloning and characterization of Bacillus subtilis iep, which has positive and negative effects on production of extracellular proteases
    T Tanaka
    Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan
    J Bacteriol 170:3593-600. 1988
    ..It was found by genetic and functional analyses that iep lies very close to sacU...
  99. ncbi request reprint Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell
    H Sakamoto
    Laboratory of Brain Science, Faculty of Integrated Arts and Sciences, Hiroshima University, Japan
    Neuroscience 126:325-34. 2004
    ..Progesterone may promote dendritic growth, spinogenesis and synaptogenesis via 25-Dx as well as its nuclear receptor in the Purkinje cell in the neonate...
  100. ncbi request reprint Cloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequence
    D Chu
    Laboratory of Molecular Clinical Chemistry, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    J Biol Chem 276:14004-13. 2001
    ..Our results suggested that LUN might be an important trans-acting transcriptional regulator for lung cancer-associated genes including E-cadherin and talin genes...
  101. ncbi request reprint Exaggerated response of arginine vasopressin-enhanced green fluorescent protein fusion gene to salt loading without disturbance of body fluid homeostasis in rats
    T Fujio
    Department of Occupational Health, Matsushita Science Center of Industrial Hygiene, Kadoma, Japan
    J Neuroendocrinol 18:776-85. 2006
    ..The AVP-eGFP transgenic rat gives us a new opportunity to study the dynamics of the AVP system in vivo...