Kenji Kawada

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. pmc Successful outcome after laparoscopic surgery for sporadic colonic desmoid tumor with β-catenin mutation: a case report
    Shutaro Gunji
    Department of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara cho, Sakyo ku, Kyoto, 606 8507, Japan
    J Med Case Rep 7:100. 2013
  2. doi request reprint Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer
    Kenji Kawada
    Department of Surgery, Kyoto University, Kyoto, Japan
    Clin Cancer Res 18:1696-703. 2012
  3. doi request reprint Molecular mechanisms of liver metastasis
    Kenji Kawada
    Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara cho, Sakyo ku, Kyoto, 606 8507, Japan
    Int J Clin Oncol 16:464-72. 2011
  4. doi request reprint The role of CXCR3 and CXCR4 in colorectal cancer metastasis
    Teppei Murakami
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int J Cancer 132:276-87. 2013
  5. doi request reprint Inhibitory role of Gas6 in intestinal tumorigenesis
    Reiko Akitake-Kawano
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Carcinogenesis 34:1567-74. 2013
  6. doi request reprint Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis
    Ryo Matsusue
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    Ann Surg Oncol 16:2645-53. 2009
  7. doi request reprint Efficacy of transanal drainage for anastomotic leakage after laparoscopic low anterior resection of the rectum
    Kae Okoshi
    Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Asian J Endosc Surg 6:90-5. 2013
  8. doi request reprint Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells
    Masatoshi Akagami
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Ann Surg Oncol 18:3868-77. 2011
  9. doi request reprint Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer
    Shigeru Kato
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Surg Res 176:430-6. 2012
  10. doi request reprint Dclk1 distinguishes between tumor and normal stem cells in the intestine
    Yuki Nakanishi
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Nat Genet 45:98-103. 2013

Collaborators

Detail Information

Publications14

  1. pmc Successful outcome after laparoscopic surgery for sporadic colonic desmoid tumor with β-catenin mutation: a case report
    Shutaro Gunji
    Department of Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara cho, Sakyo ku, Kyoto, 606 8507, Japan
    J Med Case Rep 7:100. 2013
    ..The etiology of desmoid tumors is unknown, but their association with a history of abdominal surgery, trauma, and estrogen therapy is well known...
  2. doi request reprint Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer
    Kenji Kawada
    Department of Surgery, Kyoto University, Kyoto, Japan
    Clin Cancer Res 18:1696-703. 2012
    ..However, the relationship between FDG accumulation and KRAS/BRAF mutations has not yet been investigated. The purpose of this study was to investigate whether KRAS/BRAF mutations affect FDG accumulation in CRC...
  3. doi request reprint Molecular mechanisms of liver metastasis
    Kenji Kawada
    Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara cho, Sakyo ku, Kyoto, 606 8507, Japan
    Int J Clin Oncol 16:464-72. 2011
    ..Here, we discuss recent preclinical and clinical data supporting the view that chemokine pathways are potential therapeutic targets for liver metastasis of colorectal cancer...
  4. doi request reprint The role of CXCR3 and CXCR4 in colorectal cancer metastasis
    Teppei Murakami
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int J Cancer 132:276-87. 2013
    ..These results indicate that targeting CXCR3 and CXCR4 can be a promising therapy against CRC metastasis...
  5. doi request reprint Inhibitory role of Gas6 in intestinal tumorigenesis
    Reiko Akitake-Kawano
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Carcinogenesis 34:1567-74. 2013
    ..These results suggest a novel therapeutic approach for colorectal cancer patients by regulation of stromal immune responses. ..
  6. doi request reprint Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis
    Ryo Matsusue
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    Ann Surg Oncol 16:2645-53. 2009
    ..However, the function and mechanism of the SDF-1/CXCR4 system in the metastasis of colorectal cancer remain controversial...
  7. doi request reprint Efficacy of transanal drainage for anastomotic leakage after laparoscopic low anterior resection of the rectum
    Kae Okoshi
    Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Asian J Endosc Surg 6:90-5. 2013
    ..Anastomotic leakage remains a devastating complication following low anterior resection of the rectum. Our aim was to retrospectively assess the efficacy of transanal drainage...
  8. doi request reprint Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells
    Masatoshi Akagami
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Ann Surg Oncol 18:3868-77. 2011
    ..However, the molecular basis of antiproliferative action by IFN-γ remains elusive. Here we demonstrate that IFN-γ induces transcriptional factor Prox1, and we explore the link between Prox1 and the IFN-γ system in ESCC cells...
  9. doi request reprint Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer
    Shigeru Kato
    Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Surg Res 176:430-6. 2012
    ..In this study, we investigated the usefulness of fluorescence diagnosis using 5-ALA for the detection of lymph node metastasis in a mouse model of colon cancer...
  10. doi request reprint Dclk1 distinguishes between tumor and normal stem cells in the intestine
    Yuki Nakanishi
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Nat Genet 45:98-103. 2013
    ..Our data suggest the potential for developing a therapy for colorectal cancer based on targeting Dclk1-positive TSCs...
  11. doi request reprint Human CD1c+ Myeloid Dendritic Cells Acquire a High Level of Retinoic Acid-Producing Capacity in Response to Vitamin D3
    Takayuki Sato
    Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606 8507, Japan
    J Immunol 191:3152-60. 2013
    ..The "vitamin D - CD1c(+) mDC - RA" axis may constitute an important immune component for maintaining tissue homeostasis in humans. ..
  12. ncbi request reprint Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes
    Kenji Kawada
    Department of Pharmacology, Graduate School of Medicine, Kyoto University, Kyoto
    Cancer Res 64:4010-7. 2004
    ..These results suggest that CXCR3 inhibitors may be promising therapeutic agents for treatment of LN metastasis, including that of melanoma...
  13. pmc Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α
    Keitaro Kanda
    Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    EMBO Mol Med 4:396-411. 2012
    ..Our results demonstrate that gastric cancer cell growth is maintained by autonomous TNF-α-NF-κB and IL-6-STAT3 signalling, and that NRDc and ADAM proteases turn on these signalling cascades by stimulating ectodomain shedding of TNF-α...
  14. doi request reprint Significance and mechanism of lymph node metastasis in cancer progression
    Kenji Kawada
    Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Cancer Res 71:1214-8. 2011
    ....