Tomoya Katakai

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. ncbi request reprint A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, Japan
    Int Immunol 16:1133-42. 2004
  2. pmc Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, 53 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    J Exp Med 200:783-95. 2004
  3. ncbi request reprint Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/K+-ATPase-reactive TCR transgenic mouse
    Tomoya Katakai
    Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Immunol 177:7858-67. 2006
  4. ncbi request reprint Transcription-coupled events associating with immunoglobulin switch region chromatin
    Yukiko Nambu
    Center for Molecular Biology and Genetics, Kyoto University, 53 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Science 302:2137-40. 2003
  5. pmc The balance between Pax5 and Id2 activities is the key to AID gene expression
    Hiroyuki Gonda
    Center for Molecular Biology and Genetics, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    J Exp Med 198:1427-37. 2003
  6. ncbi request reprint Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs
    Tomoya Katakai
    Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Japan
    J Immunol 181:6189-200. 2008
  7. ncbi request reprint CpG inhibits IgE class switch recombination through suppression of NF kappa B activity, but not through Id2 or Bcl6
    Takashi Kusunoki
    Department of Pediatrics, Kyoto University Graduate School of Medicine, Sakyo ku, Kyoto 606 8507, Japan
    Biochem Biophys Res Commun 328:499-506. 2005
  8. ncbi request reprint A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion
    Takahiro Hara
    Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int Immunol 18:301-11. 2006
  9. ncbi request reprint Th1-biased tertiary lymphoid tissue supported by CXC chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, Japan
    J Immunol 171:4359-68. 2003
  10. pmc Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation
    Jong Hwan Lee
    Center for Molecular Biology and Genetics, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    J Cell Biol 167:327-37. 2004

Collaborators

Detail Information

Publications17

  1. ncbi request reprint A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, Japan
    Int Immunol 16:1133-42. 2004
    ..Taken together, the findings obtained in this study provide new insights into how the LN stromal reticulum works as a specialized 'immuno-platform' for tissue compartmentalization and the immune response...
  2. pmc Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, 53 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    J Exp Med 200:783-95. 2004
    ..These findings suggest that signals from lymphocytes induce FRCs to form the network that supports the movement and interactions of immune effectors within the lymph node...
  3. ncbi request reprint Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/K+-ATPase-reactive TCR transgenic mouse
    Tomoya Katakai
    Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Immunol 177:7858-67. 2006
    ..e., the balance of self-reactivity and tolerance, in the local environment has an impact...
  4. ncbi request reprint Transcription-coupled events associating with immunoglobulin switch region chromatin
    Yukiko Nambu
    Center for Molecular Biology and Genetics, Kyoto University, 53 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Science 302:2137-40. 2003
    ..These data indicate an important role of GLT in the regulation of chromatin accessibility, strongly suggesting that the target of AID is chromatin DNA. Our results give insights on the role of AID and the regulatory mechanism of CSR...
  5. pmc The balance between Pax5 and Id2 activities is the key to AID gene expression
    Hiroyuki Gonda
    Center for Molecular Biology and Genetics, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    J Exp Med 198:1427-37. 2003
    ..Finally, enforced expression of Pax5 induces AID transcription in pro-B cell lines. Our results provide evidence that the balance between Pax5 and Id2 activities has a key role in AID gene expression...
  6. ncbi request reprint Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs
    Tomoya Katakai
    Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Japan
    J Immunol 181:6189-200. 2008
    ..These findings lead to a comprehensive view of the stromal composition and architecture of SLOs...
  7. ncbi request reprint CpG inhibits IgE class switch recombination through suppression of NF kappa B activity, but not through Id2 or Bcl6
    Takashi Kusunoki
    Department of Pediatrics, Kyoto University Graduate School of Medicine, Sakyo ku, Kyoto 606 8507, Japan
    Biochem Biophys Res Commun 328:499-506. 2005
    ..These data indicate the critical role of NF kappa B and Irf4 in the regulation of IgE CSR through actions downstream of CpG signaling...
  8. ncbi request reprint A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion
    Takahiro Hara
    Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int Immunol 18:301-11. 2006
    ..Taken together, these findings suggest that CXCL16 is an important mediator of lymphocyte-stromal interaction within lymphoid tissues...
  9. ncbi request reprint Th1-biased tertiary lymphoid tissue supported by CXC chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, Japan
    J Immunol 171:4359-68. 2003
    ..These neolymphoid tissues may maintain the local self reactivity supporting the vicious cycle of Th1-type reaction as well as autoantibody production...
  10. pmc Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation
    Jong Hwan Lee
    Center for Molecular Biology and Genetics, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
    J Cell Biol 167:327-37. 2004
    ..Thus, phosphorylated ERM has a potential function in establishing plasma membrane "posteriority" in the induction of the uropod in T lymphocytes...
  11. ncbi request reprint Chemokine-independent preference for T-helper-1 cells in transendothelial migration
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, and the Translational Research Center, Kyoto University Hospital, Kyoto 606 8507, Japan
    J Biol Chem 277:50948-58. 2002
    ....
  12. doi request reprint CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways
    Hidenori Suto
    Graduate School of Biostudies, Kyoto University, Kyoto, Japan
    Int Immunol 21:467-76. 2009
    ..Taken together, it is suggested that the maturation of lymphoid stromal cells mediated by LTbetaR is accomplished by the cooperation of multiple signaling cascades...
  13. doi request reprint Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function
    Satoshi Tanaka
    Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    J Immunol 185:2295-305. 2010
    ..It also changes the dependency of disease development on environmental stimuli. These findings collectively provide a model of how genetic anomaly of T cell signaling contributes to the development of autoimmune disease...
  14. ncbi request reprint Essential role of Id2 in negative regulation of IgE class switching
    Manabu Sugai
    Center for Molecular Biology and Genetics, Kyoto University, Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507, Japan
    Nat Immunol 4:25-30. 2003
    ..Id2 might act as molecular safeguard to suppress IgE CSR to prevent serious complications such as allergic hypersensitivity during the normal course of immune responses...
  15. ncbi request reprint In vitro induction of adult hepatic progenitor cells into insulin-producing cells
    Natsuki Nakajima-Nagata
    Center for Molecular Biology and Genetics, Kyoto University, 53 Kawahara cho Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    Biochem Biophys Res Commun 318:625-30. 2004
    ....
  16. ncbi request reprint Selective accumulation of type 1 effector cells expressing P-selectin ligand and/or alpha(4)beta(7)-integrin at the lesions of autoimmune gastritis
    Tomoya Katakai
    Center for Molecular Biology and Genetics, Kyoto University, 53 Shogoin Kawahara cho, Sakyo ku, Kyoto, 606 8507, Japan
    Int Immunol 14:167-75. 2002
    ....
  17. ncbi request reprint TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice
    Takashi Kusunoki
    Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Allergy Clin Immunol 111:136-42. 2003
    ..Although the TH1/TH2 balance is important in many clinical situations, the regulatory mechanisms in vivo have not been well elucidated...