T Kaneko

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. ncbi Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 24:5370-80. 2004
  2. ncbi Medullary dorsal horn neurons providing axons to both the parabrachial nucleus and thalamus
    Jinlian Li
    Department of Anatomy and K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China
    J Comp Neurol 498:539-51. 2006
  3. ncbi Dynorphin is expressed primarily by GABAergic neurons that contain galanin in the rat dorsal horn
    Thomas C P Sardella
    Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ UK
    Mol Pain 7:76. 2011
  4. ncbi Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia
    B K Y Bitanihirwe
    McLean Hospital, Belmont, MA, USA
    BMC Psychiatry 9:71. 2009
  5. ncbi Complementary distribution of vesicular glutamate transporters in the central nervous system
    Takeshi Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, 606 8501, Kyoto, Japan
    Neurosci Res 42:243-50. 2002
  6. ncbi Immunohistochemical localization of candidates for vesicular glutamate transporters in the rat brain
    Takeshi Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 444:39-62. 2002
  7. ncbi Predominant information transfer from layer III pyramidal neurons to corticospinal neurons
    T Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 423:52-65. 2000
  8. ncbi Chemical organization of projection neurons in the rat accumbens nucleus and olfactory tubercle
    L Zhou
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida Konoe cho Sakyo ku, Kyoto 606 8501, Japan
    Neuroscience 120:783-98. 2003
  9. ncbi Immunocytochemical localization of candidates for vesicular glutamate transporters in the rat cerebral cortex
    F Fujiyama
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    J Comp Neurol 435:379-87. 2001
  10. ncbi Radial glia is a progenitor of neocortical neurons in the developing cerebral cortex
    N Tamamaki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida Konoecho, Sakyoku, 606 8501, Kyoto, Japan
    Neurosci Res 41:51-60. 2001

Detail Information

Publications95

  1. ncbi Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 24:5370-80. 2004
    ....
  2. ncbi Medullary dorsal horn neurons providing axons to both the parabrachial nucleus and thalamus
    Jinlian Li
    Department of Anatomy and K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China
    J Comp Neurol 498:539-51. 2006
    ....
  3. ncbi Dynorphin is expressed primarily by GABAergic neurons that contain galanin in the rat dorsal horn
    Thomas C P Sardella
    Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ UK
    Mol Pain 7:76. 2011
    ..The main aims were to estimate the proportion of neurons in each of laminae I-III that express dynorphin and to determine whether they are excitatory or inhibitory neurons...
  4. ncbi Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia
    B K Y Bitanihirwe
    McLean Hospital, Belmont, MA, USA
    BMC Psychiatry 9:71. 2009
    ....
  5. ncbi Complementary distribution of vesicular glutamate transporters in the central nervous system
    Takeshi Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, 606 8501, Kyoto, Japan
    Neurosci Res 42:243-50. 2002
    ..This complementary distribution might suggest that the two VGluTs have an as yet unknown difference in functions...
  6. ncbi Immunohistochemical localization of candidates for vesicular glutamate transporters in the rat brain
    Takeshi Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 444:39-62. 2002
    ..The present results indicate that DNPI and VGluT1 are used by different neural components in most, if not all, brain regions, suggesting the complementary functions of DNPI and VGluT1...
  7. ncbi Predominant information transfer from layer III pyramidal neurons to corticospinal neurons
    T Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 423:52-65. 2000
    ..Corticothalamic neurons are, in contrast, considered relatively independent of, or indirectly related to, information processing of the superficial cortical layers...
  8. ncbi Chemical organization of projection neurons in the rat accumbens nucleus and olfactory tubercle
    L Zhou
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida Konoe cho Sakyo ku, Kyoto 606 8501, Japan
    Neuroscience 120:783-98. 2003
    ....
  9. ncbi Immunocytochemical localization of candidates for vesicular glutamate transporters in the rat cerebral cortex
    F Fujiyama
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    J Comp Neurol 435:379-87. 2001
    ..These results indicate that DNPI is located on the membrane of synaptic vesicles in thalamocortical axon terminals, and that it may be a candidate for VGluT of thalamocortical glutamatergic neurons...
  10. ncbi Radial glia is a progenitor of neocortical neurons in the developing cerebral cortex
    N Tamamaki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida Konoecho, Sakyoku, 606 8501, Kyoto, Japan
    Neurosci Res 41:51-60. 2001
    ..Here, we propose that the radial glia is a progenitor of neocortical neurons, and that a significant number of radially migrating neurons is guided by their own radial processes connected to the pia mater...
  11. ncbi GABAergic basal forebrain neurons that express receptor for neurokinin B and send axons to the cerebral cortex
    Takahiro Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    J Comp Neurol 473:43-58. 2004
    ....
  12. ncbi Characterization of neocortical non-pyramidal neurons expressing preprotachykinins A and B: a double immunofluorescence study in the rat
    T Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Japan
    Neuroscience 86:765-81. 1998
    ....
  13. ncbi Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: an immunohistochemical study with a monoclonal antibody
    A Neki
    Department of Biological Sciences, Kyoto University, Japan
    Neurosci Lett 202:197-200. 1996
    ..The results indicate that mGluR2 is located not only presynaptically but also postsynaptically...
  14. ncbi In vivo transduction of central neurons using recombinant Sindbis virus: Golgi-like labeling of dendrites and axons with membrane-targeted fluorescent proteins
    T Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Histochem Cytochem 49:1497-508. 2001
    ..Occasionally there were retrogradely labeled neurons that showed Golgi stain-like images. These results indicate that palGFP Sindbis virus can be used as an excellent anterograde tracer in the central nervous system...
  15. ncbi Cell migration from the corticostriatal angle to the basal telencephalon in rat embryos
    N Tamamaki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Japan
    Neuroreport 12:775-80. 2001
    ..These data indicated that the majority of neurons in the dense cell layer of the olfactory tubercle reached this point through the LCS. One of the origins of the cells in the LCS would be in the corticostriatal angle...
  16. ncbi Changes of immunocytochemical localization of vesicular glutamate transporters in the rat visual system after the retinofugal denervation
    Fumino Fujiyama
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    J Comp Neurol 465:234-49. 2003
    ..Thus, the present results support the notion that the retinofugal pathways are glutamatergic, and indicate that VGluT2, but not VGluT1, is employed for accumulating glutamate into synaptic vesicles of retinofugal axons...
  17. ncbi Efferent and afferent connections of GABAergic neurons in the supratrigeminal and the intertrigeminal regions. An immunohistochemical tract-tracing study in the GAD67-GFP knock-in mouse
    Jin-Lian Li
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    Neurosci Res 51:81-91. 2005
    ..Some of these GABAergic neurons may represent Vm-premotor neurons that receive nociceptive input from the Vc to elicit jaw-opening reflex by inhibiting jaw-closing Vm-motoneurons...
  18. ncbi Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum
    Wakoto Matsuda
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    J Neurosci 29:444-53. 2009
    ..Thus, these results would also contribute to understanding the clinicopathology of Parkinson's disease and related syndromes...
  19. ncbi Vesicular glutamate transporter 3-expressing nonserotonergic projection neurons constitute a subregion in the rat midbrain raphe nuclei
    Hiroyuki Hioki
    Department of Morphological Brain Science, Kyoto University, Japan
    J Comp Neurol 518:668-86. 2010
    ..These results suggest that VGLUT3-expressing nonserotonergic neurons in the midbrain raphe nuclei are preferentially distributed in the DRDSh and modulate many brain regions with the neurotransmitter glutamate via ascending axons...
  20. ncbi Differential distribution of vesicular glutamate transporters in the rat cerebellar cortex
    H Hioki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Yoshida Konoe cho Sakyo ku, Japan
    Neuroscience 117:1-6. 2003
    ..Thus, it would be the next interesting issue to determine whether mossy-fiber terminals co-expressing VGluT1 and VGluT2 show synaptic facilitation or depression...
  21. ncbi Trans-synaptically induced bursts in regular spiking non-pyramidal cells in deep layers of the cat motor cortex
    Y Kang
    Department of Physiology, Faculty of Medicine, Kyoto University, Japan
    Cereb Cortex 9:77-89. 1999
    ..The multipolar neurons displaying bursts of attenuated spikes may mediate the recurrent inhibition of pyramidal tract cells...
  22. ncbi Vesicular glutamate transporter immunoreactivity in the central and peripheral endings of muscle-spindle afferents
    Sheng Xi Wu
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Brain Res 1011:247-51. 2004
    ..VGLUT1 might be expressed not only in the central axon terminals but also in the peripheral sensory endings of muscle-spindle afferents...
  23. ncbi Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum
    A Neki
    Department of Biological Sciences, Faculty of Medicine, Kyoto University, Japan
    Neuroscience 75:815-26. 1996
    ....
  24. ncbi Efficient gene transduction of neurons by lentivirus with enhanced neuron-specific promoters
    H Hioki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Gene Ther 14:872-82. 2007
    ..Furthermore, the transcriptional activity and neuronal specificity of E/SYN promoter were sustained for up to 8 weeks. Thus, lentivirus with E/SYN promoter is the best vector for strong persistent expression in neurons...
  25. ncbi Immunohistochemical localization of a metabotropic glutamate receptor, mGluR7, in ganglion neurons of the rat; with special reference to the presence in glutamatergic ganglion neurons
    J L Li
    Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan
    Neurosci Lett 204:9-12. 1996
    ..The results indicate that virtually all sensory ganglion neurons are glutamatergic and equipped with mGluR7...
  26. ncbi Immunohistochemical localization of prostaglandin EP3 receptor in the rat nervous system
    K Nakamura
    Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Japan
    J Comp Neurol 421:543-69. 2000
    ..The characteristic distribution of EP3R provides valuable information on the mechanisms for various physiologic actions of prostaglandin E2 in the central and peripheral nervous systems...
  27. ncbi Independent inputs by VGLUT2- and VGLUT3-positive glutamatergic terminals onto rat sympathetic preganglionic neurons
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8501, Japan
    Neuroreport 15:431-6. 2004
    ..These results indicate at least two independent glutamatergic terminal populations, which include a distinct monoaminergic subpopulation, making excitatory inputs onto SPNs...
  28. ncbi [Present status and future aspects of studies on neuronal network formation (discussion)]
    Shigetada Nakanishi
    Tanpakushitsu Kakusan Koso 49:205-25. 2004
  29. ncbi Evidence that Sema3A and Sema3F regulate the migration of GABAergic neurons in the developing neocortex
    Nobuaki Tamamaki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Konoecho, Yoshida, Sakyoku, Kyoto, 606 8501 Japan
    J Comp Neurol 455:238-48. 2003
    ..Finally, the semaphorin-neuropilin interactions sorted GABAergic inteneurons into the CP and white matter neurons into the IZ...
  30. ncbi Sympathetic premotor neurons mediating thermoregulatory functions
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8501, Japan
    Neurosci Res 51:1-8. 2005
    ..The VGLUT3-expressing premotor neurons would mediate thermoregulation including fever induction, and could be also involved in the control of energy metabolism...
  31. ncbi Demonstration of long-range GABAergic connections distributed throughout the mouse neocortex
    Ryohei Tomioka
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    Eur J Neurosci 21:1587-600. 2005
    ..The GABAergic projection neurons preferentially received neocortical inputs. From these results, we conclude that GABAergic projection neurons are distributed throughout the neocortex and are part of a corticocortical network...
  32. ncbi The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area
    Kazuhiro Nakamura
    Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Department of Intelligence Science and Technology, Japan Science and Technology, Sakyo ku, Kyoto 606 8502, Japan
    J Neurosci 22:4600-10. 2002
    ..Our results demonstrate that the rRPa, which has never been associated with the fever mechanism, mediates the pyrogenic neurotransmission from the POA to the peripheral sympathetic effectors contributing to fever development...
  33. ncbi Two types of thalamocortical projections from the motor thalamic nuclei of the rat: a single neuron-tracing study using viral vectors
    Eriko Kuramoto
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Cereb Cortex 19:2065-77. 2009
    ....
  34. ncbi Afferent islands are larger than mu-opioid receptor patch in striatum of rat pups
    Kouichi C Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto, Japan
    Neuroreport 20:584-8. 2009
    ..These results suggest that the striatal 'afferent islands' are larger than MOR patches in the early postnatal life...
  35. ncbi Recurrent infomax generates cell assemblies, neuronal avalanches, and simple cell-like selectivity
    Takuma Tanaka
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Neural Comput 21:1038-67. 2009
    ....
  36. ncbi Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse
    Nobuaki Tamamaki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 467:60-79. 2003
    ..4% of the GFP-positive cells. They accounted for 6.5% in layer I. In accord with unidentified GFP-positive cells, many medium-sized spherical somata emitting intense GFP fluorescence were observed in layer I...
  37. ncbi Enhancement of glutaminase-like immunoreactivity in rat brain by an irreversible inhibitor of the enzyme
    T Kaneko
    Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan
    Brain Res Bull 28:897-907. 1992
    ..These results suggested that DON induced a new massive synthesis of glutaminase in the affected neurons...
  38. ncbi Preprodynorphin-, preproenkephalin-, preprotachykinin A- and preprotachykinin B-immunoreactive neurons in the accumbens nucleus and olfactory tubercle: double-immunofluorescence analysis
    T Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    Neuroscience 114:611-27. 2002
    ....
  39. ncbi Glutamate-synthesizing enzymes in GABAergic neurons of the neocortex: a double immunofluorescence study in the rat
    T Kaneko
    Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan
    Neuroscience 61:839-49. 1994
    ..Mitochondrial aspartate aminotransferase was located in perikarya, rather than in axon terminals of GABAergic neurons, suggesting a transmitter-irrelevant role of this enzyme in neurons...
  40. ncbi Prostaglandin EP3 receptor protein in serotonin and catecholamine cell groups: a double immunofluorescence study in the rat brain
    K Nakamura
    Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Neuroscience 103:763-75. 2001
    ....
  41. ncbi Production and histological application of affinity-purified antibodies to heat-denatured green fluorescent protein
    Kouichi C Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Histochem Cytochem 56:647-57. 2008
    ..This manuscript contains online supplemental material at http://www.jhc.org. Please visit this article online to view these materials...
  42. ncbi Transiently increased colocalization of vesicular glutamate transporters 1 and 2 at single axon terminals during postnatal development of mouse neocortex: a quantitative analysis with correlation coefficient
    Kouichi Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Eur J Neurosci 26:3054-67. 2007
    ..As VGLUT1 is often used in axon terminals that show synaptic plasticity in adult brain, the present findings suggest that VGLUT1 is used in thalamocortical axons transiently during the postnatal period when plasticity is required...
  43. ncbi High-level transgene expression in neurons by lentivirus with Tet-Off system
    Hiroyuki Hioki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Neurosci Res 63:149-54. 2009
    ..These results suggest that the present method is valuable for strong gene transduction and clear visualization of neurons in vivo...
  44. ncbi Chemically specific circuit composed of vesicular glutamate transporter 3- and preprotachykinin B-producing interneurons in the rat neocortex
    Hiroyuki Hioki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Cereb Cortex 14:1266-75. 2004
    ..Thus, VGLUT3-expressing GABAergic interneurons form a chemically specific circuit within the PPTB-producing interneuron group and it is likely that glutamate is used within the chemically specific circuit...
  45. ncbi Metabotropic glutamate receptor 4-immunopositive terminals of medium-sized spiny neurons selectively form synapses with cholinergic interneurons in the rat neostriatum
    Eriko Kuramoto
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 500:908-22. 2007
    ..These findings indicate that the mGluR4-positive terminals of MSN axon collaterals selectively form synapses with neostriatal cholinergic interneurons...
  46. ncbi Targeting green fluorescent protein to dendritic membrane in central neurons
    Hiroshi Kameda
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Neurosci Res 61:79-91. 2008
    ..Thus, myrGFP-LDLRct is an excellent synthetic protein for dendritic visualization, and may be a useful tool for the morphological analysis of neuronal circuits...
  47. ncbi In vivo function of Rnd2 in the development of neocortical pyramidal neurons
    Kazuhiro Nakamura
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Neurosci Res 54:149-53. 2006
    ..These results indicate that Rnd2 functions in vivo as a regulator of the migration and morphological changes associated with the development of pyramidal neurons...
  48. ncbi The role of Ca2+-dependent cationic current in generating gamma frequency rhythmic bursts: modeling study
    T Aoyagi
    Department of Applied Analysis and Complex Dynamical Systems, Kyoto University, Sakyoku, 606-8501, Kyoto, Japan
    Neuroscience 115:1127-38. 2002
    ....
  49. ncbi Presynaptic localization of an AMPA-type glutamate receptor in corticostriatal and thalamostriatal axon terminals
    Fumino Fujiyama
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Japan
    Eur J Neurosci 20:3322-30. 2004
    ....
  50. ncbi Difference in organization of corticostriatal and thalamostriatal synapses between patch and matrix compartments of rat neostriatum
    Fumino Fujiyama
    Department of Morphological Brain Science, Graduate School of Medicine, Faculty of Medicine, Kyoto University, Kyoto 606-8501, Japan
    Eur J Neurosci 24:2813-24. 2006
    ....
  51. ncbi The effects of cutting solutions on the viability of GABAergic interneurons in cerebral cortical slices of adult mice
    Yasuyo Tanaka
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci Methods 171:118-25. 2008
    ..This method would thus be useful for electrophysiological and morphological studies of cortical interneurons in slice preparations of the adult brain...
  52. ncbi Neurokinin B-producing projection neurons in the lateral stripe of the striatum and cell clusters of the accumbens nucleus in the rat
    Ligang Zhou
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    J Comp Neurol 480:143-61. 2004
    ....
  53. ncbi Paucity of enkephalin production in neostriatal striosomal neurons: analysis with preproenkephalin-green fluorescent protein transgenic mice
    Yoshinori Koshimizu
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Eur J Neurosci 28:2053-64. 2008
    ....
  54. ncbi Septal neurons in barrel cortex derive their receptive field input from the lemniscal pathway
    Takahiro Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 29:4089-95. 2009
    ..This result provides the missing piece of evidence for a separate pathway of vibrissal information that projects to septal columns of the barrel cortex...
  55. ncbi Corticofugal control of vibrissa-sensitive neurons in the interpolaris nucleus of the trigeminal complex
    Takahiro Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 30:1832-8. 2010
    ..It is proposed that top-down control of brainstem circuits is prompted by motor strategies, expectations, and motivational states of the animal...
  56. ncbi [Novel method for the single-cell structural analysis of neuronal processes--labeling with viral vectors]
    Takeshi Kaneko
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Brain Nerve 62:209-20. 2010
    ....
  57. ncbi Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone
    Sheng Xi Wu
    Department of Morphological Brain Science and Laboratory of Immunological Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    Proc Natl Acad Sci U S A 102:17172-7. 2005
    ..Our data suggest that NEX-positive progenitors within the SVZ are committed to a glutamatergic neuronal fate and have evolved to expand the number of cortical output neurons that is characteristic for the mammalian forebrain...
  58. ncbi Regulation of gap junction protein (connexin) genes and function in differentiating ES cells
    M Oyamada
    Department of Pathology and Cell Regulation, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Methods Mol Biol 185:63-9. 2002
  59. ncbi Third pathway in the cortico-basal ganglia loop: Neurokinin B-producing striatal neurons modulate cortical activity via striato-innominato-cortical projection
    Takahiro Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
    Neurosci Res 54:1-10. 2006
    ....
  60. ncbi Inhibitory gating of vibrissal inputs in the brainstem
    Takahiro Furuta
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 28:1789-97. 2008
    ....
  61. ncbi Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep
    A Mizoguchi
    Department of Anatomy and Neurobiology, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8501, Japan
    Proc Natl Acad Sci U S A 98:11674-9. 2001
    ..These results indicate that DPs in the arachnoid trabecular cells of the basal forebrain mediate an increase in the extracellular adenosine level and sleep induction by PGD(2)...
  62. ncbi Sound-intensity-dependent compensation for the small interaural time difference cue for sound source localization
    Eri Nishino
    Departments of Physiology and Morphological Brain Science, Faculty of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Neurosci 28:7153-64. 2008
    ..Thus, the small ITD cues available in low-frequency sounds were partly compensated for by a sound-intensity-dependent inhibition from the SON...
  63. ncbi Complementary roles of cholecystokinin- and parvalbumin-expressing GABAergic neurons in hippocampal network oscillations
    Thomas Klausberger
    Medical Research Council Anatomical Neuropharmacology Unit, Oxford University, Oxford OX1 3TH, United Kingdom
    J Neurosci 25:9782-93. 2005
    ....
  64. ncbi Intracellularly labeled pyramidal neurons in the cortical areas projecting to the spinal cord. II. Intra- and juxta-columnar projection of pyramidal neurons to corticospinal neurons
    Ryong-Ho Cho
    Department of Developmental and Reconstructive Medicine, Division of Oral and Maxillofacial Surgery, Course of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8102, Japan
    Neurosci Res 50:395-410. 2004
    ..In contrast, inputs with tonic response properties from the other layers seem to be integrated in corticospinal neurons, and might be useful in maintaining the activity of corticospinal neurons...
  65. ncbi Expression of D1 but not D2 dopamine receptors in striatal neurons producing neurokinin B in rats
    Takahiro Sonomura
    Department of Anatomy for Oral Sciences, Graduate School of Medical and Dental Sciences, Advanced Therapeutic Course, Field of Neurology, Kagoshima University, Kagoshima 890 8544, Japan
    Eur J Neurosci 26:3093-103. 2007
    ....
  66. ncbi Predicting spike timings of current-injected neurons
    Yasuhiro Tsubo
    Neural Netw 17:165-73. 2004
    ..The biological neurons we examined were distinctly classified into two types according to the estimated percent contents of those ionic channels...
  67. ncbi Some gamma-motoneurons contain gamma-aminobutyric acid in the rat cervical spinal cord
    Tetsufumi Ito
    Department of Anatomy, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki, Fukui 910 1193, Japan
    Brain Res 1201:78-87. 2008
    ..Since we detected neither GABAA nor GABAB receptors in the TBM by RT-PCR, the function of the GABA-containing gamma-motoneurons remains unclear...
  68. ncbi Novel strategy to selectively label excitatory and inhibitory neurons in the cerebral cortex of mice
    Kaustuv Basu
    Department of Psychiatry, Faculty of Medicine, Centre de Recherche Universite Laval Robert Giffard, 2601, chemin de la Canardiere, Quebec, G1J 2G3 Canada
    J Neurosci Methods 170:212-9. 2008
    ..This technique can thus be used to differentiate excitatory axonal projections from inhibitory ones, and represent a unique tool in neuronal circuit analysis...
  69. ncbi Intracellularly labeled pyramidal neurons in the cortical areas projecting to the spinal cord. I. Electrophysiological properties of pyramidal neurons
    Ryong-Ho Cho
    Department of Developmental and Reconstructive Medicine, Division of Oral and Maxillofacial Surgery, Course of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8102, Japan
    Neurosci Res 50:381-94. 2004
    ..Although weak stimulation of areas FL/HL and M1 is known to elicit movement, these results suggest different information processings between the two areas...
  70. ncbi Expression of vesicular glutamate transporters, VGluT1 and VGluT2, in axon terminals of nociceptive primary afferent fibers in the superficial layers of the medullary and spinal dorsal horns of the rat
    Jin Lian Li
    Department of Anatomy and K K Leung Brain Research Centre, The Fourth Military Medical University, Xi an 710032, People s Republic of China
    J Comp Neurol 457:236-49. 2003
    ....
  71. ncbi Honeycomb-like mosaic at the border of layers 1 and 2 in the cerebral cortex
    Noritaka Ichinohe
    Laboratory for Cortical Organization and Systematics, RIKEN, Brain Science Institute, Wako, Saitama 351 0198, Japan
    J Neurosci 23:1372-82. 2003
    ..Results from parvalbumin staining show that the honeycomb mosaic is not limited to rat visual cortex but can be recognized at the layer 1-2 border in other areas and species...
  72. ncbi Cellular localization of three vesicular glutamate transporter mRNAs and proteins in rat spinal cord and dorsal root ganglia
    Alexandre L R Oliveira
    Department of Neuroscience, The Retzius Laboratory, Karolinska Institutet, SE-171 77 Stockholm, Sweden
    Synapse 50:117-29. 2003
    ..VGLUT1 is mainly present in primary afferents from large, CGRP-negative DRG neurons, VGLUT2 has mainly a local origin, and VGLUT3 fibers probably have a supraspinal origin...
  73. ncbi Direct projections from substance P-containing neurons to nitric oxide synthase-containing interneurons in the rat striatum
    Jin Lian Li
    Department of Anatomy and K.K. Leung Brain Research Center, The Fourth Military Medical University, 710032, Xi'an, People's Republic of China
    Neurosci Lett 318:133-6. 2002
    ..On the basis of these present and previous data, possible synaptic and non-synaptic interactions between SP-PN and NOS-IN in the striatum were discussed...
  74. ncbi Synaptic association of dopaminergic axon terminals and neurokinin-1 receptor-expressing intrinsic neurons in the striatum of the rat
    Jin-Lian Li
    Department of Anatomy and K.K. Leung Brain Research Center, The Fourth Military Medical University, Xi'an 710032, People's Republic of China
    Neurosci Lett 324:9-12. 2002
    ..631 (1993) 297; Neurosci. Lett. 310 (2001) 109), the present results indicate that dopaminergic neurons make synapses upon these intrinsic neurons in the striatum...
  75. ncbi Task-dependent and cell-type-specific Fos enhancement in rat sensory cortices during audio-visual discrimination
    Shuzo Sakata
    Speciation Mechanisms I, National Institute for Basic Biology, Okazaki 444-8585, Japan
    Eur J Neurosci 15:735-43. 2002
    ..These results suggest that modulation in cortical excitatory neurons might have critical roles in selecting and processing behaviourally relevant sensory stimuli...
  76. ncbi Organization and development of corticocortical associative neurons expressing the orphan nuclear receptor Nurr1
    Yasuyoshi Arimatsu
    Cortical Circuits Research Unit, Mitsubishi Kagaku Institute of Life Sciences MITILS, Tokyo 194 8511, Japan
    J Comp Neurol 466:180-96. 2003
    ..These results raise the possibility that Nurr1 plays a role in the establishment and maintenance of normal corticocortical circuitry and function...
  77. ncbi Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus
    Yoshiko Nakamura
    Neurological Sciences Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Eur J Neurosci 22:3137-46. 2005
    ..These results suggest that a direct projection of EP3 receptor-expressing POA neurons to the DMH/DH region mediates febrile responses via a GABAergic mechanism...
  78. ncbi Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra
    Raquel Martín-Ibáñez
    Laboratory for Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Scheeles väg 1 A1
    Eur J Neurosci 23:1063-70. 2006
    ..Collectively, our data indicate that VGLUT3 identifies a novel excitatory terminal subset that contributes to the tuning of DA cell excitability in the substantia nigra...
  79. ncbi Distribution and morphological characterization of phosphate-activated glutaminase-immunoreactive neurons in cat visual cortex
    Estel Van der Gucht
    Laboratory for Neuroplasticity and Neuroproteomics, Katholieke Universiteit Leuven, Naamsestraat 59, B 3000, Leuven, Belgium
    Brain Res 988:29-42. 2003
    ..We here present PAG as a neurochemical marker to map excitatory cortical neurons that use the amino acid glutamate as their neurotransmitter in cat visual cortex...
  80. ncbi Expression of vesicular glutamate transporter 1 immunoreactivity in peripheral and central endings of trigeminal mesencephalic nucleus neurons in the rat
    You Wang Pang
    Department of Anatomy and K K Leung Brain Research Centre, The Fourth Military Medical University, Xi an 710032, China
    J Comp Neurol 498:129-41. 2006
    ..These data indicate that VGLUT1 is expressed in both the central axon terminals and the peripheral sensory endings of Vmes neurons, although no VGLUT1 immunoreactivity was detectable in the cell bodies of Vmes neurons in adult rats...
  81. ncbi The supratrigeminal region of the rat sends GABA/glycine-cocontaining axon terminals to the motor trigeminal nucleus on the contralateral side
    Yun-Qing Li
    Department of Anatomy and K.K. Leung Brain Research Center, The Fourth Military Medical University, Xi'an 710032, People's Republic of China
    Neurosci Lett 330:13-6. 2002
    ..Thus, the STR was indicated to send GABAergic/glycinergic axon terminals contralaterally to Tm motoneurons...
  82. ncbi Extensive overlap of mu-opioid and nicotinic sensitivity in cortical interneurons
    Isabelle Ferezou
    Laboratoire de Neurobiologie et Diversité Cellulaire, CNRS UMR 7637, Ecole Superieure de Physique et de Chimie Industrielles, 75005 Paris, France
    Cereb Cortex 17:1948-57. 2007
    ..Our results suggest that neocortical mu-opioid transmission acts as an inhibitory feedback onto nicotinic-responsive interneurons, which may change network excitability and inhibition patterns during cholinergic excitation...
  83. ncbi Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lungs attenuates elastase-induced pulmonary emphysema in mice
    Takeshi Shinohara
    Department of Internal Medicine and Clinical Immunology, Yokohama City University School of Medicine, Kanazawa, Yokohama, Kanagawa 236-0004, Japan
    Hum Gene Ther 16:318-27. 2005
    ..These results suggest that Ad.HO-1-induced HO-1 overexpression suppressed PPE-induced emphysema by attenuating neutrophilic inflammation via modulating cytokine and chemokine profiles in mouse lungs...
  84. ncbi Vesicular glutamate transporters, VGluT1 and VGluT2, in the trigeminal ganglion neurons of the rat, with special reference to coexpression
    Jin Lian Li
    Department of Anatomy and K K Leung Brain Research Centre, The Fourth Military Medical University, Xi an 710032, People s Republic of China
    J Comp Neurol 463:212-20. 2003
    ..Some of these axon terminals were confirmed to form the central core of the synaptic glomerulus. These results indicated that VGluT1 and VGluT2 are coexpressed in the cell bodies and axon terminals in most trigeminal ganglion neurons...
  85. ncbi Gamma-aminobutyric acid-containing sympathetic preganglionic neurons in rat thoracic spinal cord send their axons to the superior cervical ganglion
    Tetsufumi Ito
    Department of Anatomy, Faculty of Medical Sciences, University of Fukui, Fukui 910 1193, Japan
    J Comp Neurol 502:113-25. 2007
    ..Thus, the present findings strongly indicate that some sympathetic preganglionic neurons are not only cholinergic but also GABAegic...
  86. ncbi The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor
    Wataru Mishima
    Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, 3 9 Fukuura Kanazawa ku, Yokohama 236 0004 Japan
    Genes Cells 9:193-204. 2004
    ..Our data strongly support that ILK and affixin provide a novel signalling pathway that links integrin signalling to Cdc42/Rac1 activation...
  87. ncbi Pseudomonas aeruginosa-induced neutrophilic lung inflammation is attenuated by adenovirus-mediated transfer of the heme oxygenase 1 cDNA in mice
    Takahiro Tsuburai
    First Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama City 236-0004, Japan
    Hum Gene Ther 15:273-85. 2004
    ..It is thus suggested that HO-1 overexpression is useful for treating P. aeruginosa-associated lung inflammation by attenuating neutrophil influx and apoptotic cell death...
  88. ncbi Prodynorphin storage and processing in axon terminals and dendrites
    Tatiana Yakovleva
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    FASEB J 20:2124-6. 2006
    ..Regulation of PDYN storage and processing at synapses by neuronal activity or extracellular stimuli may provide a local mechanism for regulation of synaptic transmission...
  89. ncbi Orthotopic implantation of a colon cancer xenograft induces high expression of cyclooxygenase-2
    Tuyoshi Shoji
    Department of Surgery II, Hamamatsu University School of Medicine, 1 20 1 Handa yama, Hamamatsu shi, Shizuoka, 431 3192, Japan
    Cancer Lett 195:235-41. 2003
    ..The intensity of COX-2 mRNA was negatively correlated with the apoptotic index. In conclusion, COX-2 plays an important role in organ-specific metastasis of the colon cancer...
  90. ncbi cGMP activates a pH-sensitive leak K+ current in the presumed cholinergic neuron of basal forebrain
    Hiroki Toyoda
    Department of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, 1 8, Yamadaoka, Suita, Osaka, Japan
    J Neurophysiol 99:2126-33. 2008
    ..3 to 7.3, contrary to the case seen in the control condition. These observations strongly suggest that 8-Br-cGMP activates a pH- and Ba(2+)-sensitive leak K+ current expressed in the presumed BFC neurons by modulating its pH sensitivity...
  91. ncbi Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function
    Hiromi Sano
    Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima 960 1295, Japan
    J Neurosci 23:9078-88. 2003
    ..We propose a possible model in which the striatopallidal neurons dually regulate motor behavior dependent on the state of DA transmission through coordination of the basal ganglia circuitry...
  92. ncbi Truncated TrkB-T1 regulates the morphology of neocortical layer I astrocytes in adult rat brain slices
    Koji Ohira
    Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi, Kodaira, Tokyo 187 8502, Japan
    Eur J Neurosci 25:406-16. 2007
    ..Therefore, the present study provides evidence of the regulation of layer I astrocytic morphology by the BDNF-T1 signal in adult rat neocortical slices...
  93. ncbi Fos-enkephalin signaling in the rat medial vestibular nucleus facilitates vestibular compensation
    Tadashi Kitahara
    Department of Otolaryngology, Osaka University, School of Medicine, Osaka, Japan
    J Neurosci Res 83:1573-83. 2006
    ....
  94. ncbi Cellular localization of GABA and GABAB receptor subunit proteins during spermiogenesis in rat testis
    Kiyoto Kanbara
    Department of Anatomy, Osaka Medical College, Takatsuki, Osaka 569-8686, Japan
    J Androl 26:485-93. 2005
    ..These results indicate that the GABAergic system might be involved in regulation of spermiogenesis...
  95. ncbi Metastatic brain mass caused by slow-growing small-cell lung cancer: differential vascular endothelial growth factor expression in primary and metastatic tumor
    Satoshi Inoue
    Department of Internal Medicine and Clinical Immunology, Yokohama City University, School of Medicine, Kanazawa Ku, Yokohama, Japan
    Clin Lung Cancer 8:436-8. 2007
    ..Weak expression of VEGF in primary tumor might be associated with good prognosis. However, VEGF upregulation could occur after metastasis, resulting in aggressive tumor growth...