K Ito

Summary

Affiliation: Kyoto Prefectural University of Medicine
Country: Japan

Publications

  1. ncbi request reprint Left ventricular apex venting during deep hypothermia in a case of difficult re-entry into the mediastinum
    K Ito
    Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Cardiovasc Surg (Torino) 42:493-4. 2001
  2. ncbi request reprint Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats
    Kazuhiro Ito
    Department of Cardiovascular and Thoracic Surgery, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Eur J Cardiothorac Surg 25:530-6. 2004
  3. ncbi request reprint Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis
    C Sakakura
    Dept of Surgery and Regenerative Medicine, Div of Surgery and Physiology of the Digestive System, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi, Kamigyo ku, Kyoto 602 8566, Japan
    Oncogene 26:5927-38. 2007
  4. ncbi request reprint [Cardiac angiosarcoma with diagnostic difficulty]
    M Yanada
    Department of Thoracic Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Kyobu Geka 60:1148-51. 2007
  5. ncbi request reprint Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
    Kittipong Maneechotesuwan
    Section of Airway Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Immunol 178:2491-8. 2007
  6. ncbi request reprint IL-1 beta and TNF-alpha regulation of the adenosine receptor (A2A) expression: differential requirement for NF-kappa B binding to the proximal promoter
    Silvana Morello
    Airways Disease Section, NHLI Imperial College London, London, United Kingdom
    J Immunol 177:7173-83. 2006
  7. ncbi request reprint Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Italy
    Curr Med Chem 13:2267-90. 2006
  8. ncbi request reprint Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease
    Katia Varani
    Department of Clinical and Experimental Medicine, Pharmacology Unit, Via Fossato di Mortara 17 19, 44100 Ferrara, Italy
    Am J Respir Crit Care Med 173:398-406. 2006
  9. ncbi request reprint Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease
    Fabio L M Ricciardolo
    Unit of Respiratory Disease, Istituto di Ricovero e Cura a Carattere Scientifico Gaslini Institute, Genoa, Italy
    J Allergy Clin Immunol 116:1028-35. 2005
  10. ncbi request reprint Decreased histone deacetylase activity in chronic obstructive pulmonary disease
    Kazuhiro Ito
    Airway Disease Section, National Heart and Lung Institute, Imperial College, London, United Kingdom
    N Engl J Med 352:1967-76. 2005

Collaborators

  • Toshikazu Yoshikawa
  • H Yaku
  • Yuji Naito
  • T Okanoue
  • Peter J Barnes
  • James Hogg
  • L E Donnelly
  • Yasuhiro Nakagami
  • Carla Cicala
  • K Fan Chung
  • Robert Newton
  • Gaetano Caramori
  • Ian M Adcock
  • Ian Adcock
  • Silvana Morello
  • Alberto Papi
  • Elen Jazrawi
  • Karine Enesa
  • Kittipong Maneechotesuwan
  • C Sakakura
  • M Yanada
  • Kang Yun Lee
  • Katia Varani
  • Kian Fan Chung
  • Antonino Di Stefano
  • Fabio L M Ricciardolo
  • Takako Murasugi
  • Matthew C Catley
  • Borja G Cosio
  • Jonathan Dean
  • Paul C Evans
  • Chee Phua
  • Joseph Boyle
  • Ingvild Thorbjornsen
  • Dorian O Haskard
  • Yasuo To
  • Le A Luong
  • A Hagiwara
  • Y Nakase
  • S Nakashima
  • K Terauchi
  • J Shimada
  • Yao Xin
  • M Shimomura
  • Omar S Usmani
  • K I Fukuda
  • H Yamagishi
  • Y Ito
  • T Chiba
  • H Ida
  • S Kin
  • S Yazumi
  • K Miyagawa
  • Edward Leung
  • Sebastian L Johnston
  • Marco Contoli
  • Stephen Maclennan
  • Satoshi Yamamura
  • Paolo Casolari
  • Stefania Gessi
  • Giorgio Cavallesco
  • Patricia Desouza
  • Fabrizio Vincenzi
  • Gianfranco Azzena
  • Pier Andrea Borea
  • Masahiro Sakaguchi
  • Claudio F Donner
  • Andrea Rossi
  • Kazuki Hirahara
  • Tomomi Yoshitomi
  • Giovanni Abatangelo
  • Paola Brun
  • Yoshifumi Taniguchi
  • Makoto Yamashita
  • Armando Capelli
  • Joanna E Chivers
  • Andrew Beaton
  • Neil S Holden
  • K Fan Chung
  • Martin W Bergmann
  • Yasuyuki Nasuhara
  • Buphinder Mann
  • Lisa M Cambridge

Detail Information

Publications17

  1. ncbi request reprint Left ventricular apex venting during deep hypothermia in a case of difficult re-entry into the mediastinum
    K Ito
    Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    J Cardiovasc Surg (Torino) 42:493-4. 2001
    ..We found that this technique was easy, safe, and useful to prevent ventricular distention during cooling...
  2. ncbi request reprint Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats
    Kazuhiro Ito
    Department of Cardiovascular and Thoracic Surgery, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Eur J Cardiothorac Surg 25:530-6. 2004
    ..We examined the effects of pioglitazone, a synthetic ligand of PPAR-gamma, against lung ischemia-reperfusion injury in rats...
  3. ncbi request reprint Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis
    C Sakakura
    Dept of Surgery and Regenerative Medicine, Div of Surgery and Physiology of the Digestive System, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi, Kamigyo ku, Kyoto 602 8566, Japan
    Oncogene 26:5927-38. 2007
    ..Examination of RUNX3 expression in pretreatment specimens may predict radiosensitivity, and induction of RUNX3 expression may increase tumor radiosensitivity...
  4. ncbi request reprint [Cardiac angiosarcoma with diagnostic difficulty]
    M Yanada
    Department of Thoracic Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Kyobu Geka 60:1148-51. 2007
    ..Moreover, tumor marker CA125 was a good indicator of therapeutic efficacy...
  5. ncbi request reprint Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
    Kittipong Maneechotesuwan
    Section of Airway Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
    J Immunol 178:2491-8. 2007
    ..This provides a means whereby allergen exposure leads to the expression of Th2 cytokines, and this novel mechanism may provide new approaches to treating allergic diseases...
  6. ncbi request reprint IL-1 beta and TNF-alpha regulation of the adenosine receptor (A2A) expression: differential requirement for NF-kappa B binding to the proximal promoter
    Silvana Morello
    Airways Disease Section, NHLI Imperial College London, London, United Kingdom
    J Immunol 177:7173-83. 2006
    ....
  7. ncbi request reprint Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia
    Gaetano Caramori
    Centro di Ricerca su Asma e BPCO, University of Ferrara, Italy
    Curr Med Chem 13:2267-90. 2006
    ..Clearly this is an exciting new area of ongoing research with promising therapeutic potential...
  8. ncbi request reprint Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease
    Katia Varani
    Department of Clinical and Experimental Medicine, Pharmacology Unit, Via Fossato di Mortara 17 19, 44100 Ferrara, Italy
    Am J Respir Crit Care Med 173:398-406. 2006
    ..Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of mortality worldwide. Adenosine is an inflammatory regulator that acts through four distinct receptors to mediate pro- and antiinflammatory effects...
  9. ncbi request reprint Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease
    Fabio L M Ricciardolo
    Unit of Respiratory Disease, Istituto di Ricovero e Cura a Carattere Scientifico Gaslini Institute, Genoa, Italy
    J Allergy Clin Immunol 116:1028-35. 2005
    ..Reactive nitrogen species formation and nitrosative stress are potentially involved in chronic obstructive pulmonary disease (COPD) pathogenesis...
  10. ncbi request reprint Decreased histone deacetylase activity in chronic obstructive pulmonary disease
    Kazuhiro Ito
    Airway Disease Section, National Heart and Lung Institute, Imperial College, London, United Kingdom
    N Engl J Med 352:1967-76. 2005
    ..HDAC is a key molecule in the repression of production of proinflammatory cytokines in alveolar macrophages...
  11. ncbi request reprint Oral administration of a T cell epitope inhibits symptoms and reactions of allergic rhinitis in Japanese cedar pollen allergen-sensitized mice
    Takako Murasugi
    Biological Research Laboratories, Sankyo Co, Ltd, 1 2 58 Hiromachi, Shinagawa ku, Tokyo 140 8710, Japan
    Eur J Pharmacol 510:143-8. 2005
    ....
  12. ncbi request reprint Targeting Th2 cells in asthmatic airways
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Italy
    Curr Drug Targets Inflamm Allergy 3:243-55. 2004
    ..Some of these new Th2-oriented strategies may in the future not only control symptoms, but also potentially prevent or cure the disease...
  13. ncbi request reprint Transcription factors in asthma and COPD
    Gaetano Caramori
    Dipartimento di Medicina Clinica e Sperimentale, Centro di Ricerca su Asma e BPCO, Universita di Ferrara, Via Savonarola 9, Italy
    IDrugs 7:764-70. 2004
    ..Several new compounds based on interactions with specific transcription factors or their activation pathways are now in development for the treatment of asthma and COPD...
  14. ncbi request reprint Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms
    Louise E Donnelly
    Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK
    Am J Physiol Lung Cell Mol Physiol 287:L774-83. 2004
    ..3 microM), and cyclooxygenase-2 expression in these cells. This study demonstrates that resveratrol and quercetin have novel nonsteroidal anti-inflammatory activity that may have applications for the treatment of inflammatory diseases...
  15. ncbi request reprint Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma
    Borja G Cosio
    Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College Faculty of Medicine, London, United Kingdom
    Am J Respir Crit Care Med 170:141-7. 2004
    ..Glucocorticoids and theophylline may downregulate the inflammatory response by modulating HAT and HDAC activity, and nuclear factor-kappaB activation...
  16. ncbi request reprint Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding
    Matthew C Catley
    Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College, Dovehouse Street, London SW3 6LY, United Kingdom
    J Biol Chem 279:18457-66. 2004
    ....
  17. doi request reprint Hydrogen peroxide prolongs nuclear localization of NF-kappaB in activated cells by suppressing negative regulatory mechanisms
    Karine Enesa
    British Heart Foundation Cardiovascular Sciences Unit, National Heart and Lung Institute, Imperial College London, W12 ONN, United Kingdom
    J Biol Chem 283:18582-90. 2008
    ..We conclude that H(2)O(2) prolongs NF-kappaB activation in co-stimulated cells by suppressing the negative regulatory functions of Cezanne and IkappaBalpha...