Katsuhiko Hayashi

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. doi request reprint Generation of eggs from mouse embryonic stem cells and induced pluripotent stem cells
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Nat Protoc 8:1513-24. 2013
  2. pmc ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage
    Leng Siew Yeap
    Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK
    Epigenetics Chromatin 2:12. 2009
  3. doi request reprint Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Science 338:971-5. 2012
  4. doi request reprint Induction of mouse germ-cell fate by transcription factors in vitro
    Fumio Nakaki
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Nature 501:222-6. 2013
  5. doi request reprint A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants
    Shinya Aramaki
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Dev Cell 27:516-29. 2013
  6. doi request reprint PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells
    Masashi Yamaji
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Cell Stem Cell 12:368-82. 2013
  7. doi request reprint Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Cell 146:519-32. 2011
  8. doi request reprint Stepwise differentiation from naïve state pluripotent stem cells to functional primordial germ cells through an epiblast-like state
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Methods Mol Biol 1074:175-83. 2013

Collaborators

Detail Information

Publications8

  1. doi request reprint Generation of eggs from mouse embryonic stem cells and induced pluripotent stem cells
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Nat Protoc 8:1513-24. 2013
    ..This method provides an initial step toward reconstitution of the entire process of oogenesis in vitro. ..
  2. pmc ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage
    Leng Siew Yeap
    Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK
    Epigenetics Chromatin 2:12. 2009
    ..Transcriptional regulators, such as Oct4, are critical for pluripotency, but the role of epigenetic modifiers remains to be fully elucidated...
  3. doi request reprint Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Science 338:971-5. 2012
    ..Our culture system serves as a robust foundation for the investigation of key properties of female germ cells, including the acquisition of totipotency, and for the reconstitution of whole female germ cell development in vitro...
  4. doi request reprint Induction of mouse germ-cell fate by transcription factors in vitro
    Fumio Nakaki
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Nature 501:222-6. 2013
    ..Our findings provide a new insight into the transcriptional logic for PGC specification, and create a foundation for the transcription-factor-based reconstitution and regulation of mammalian gametogenesis. ..
  5. doi request reprint A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants
    Shinya Aramaki
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Dev Cell 27:516-29. 2013
    ..These findings establish the key signaling mechanism for, and a fundamental role of a mesodermal factor in, mammalian PGC specification...
  6. doi request reprint PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells
    Masashi Yamaji
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Cell Stem Cell 12:368-82. 2013
    ..PRDM14 exerts these effects by recruiting polycomb repressive complex 2 (PRC2) specifically to key targets and repressing their expression...
  7. doi request reprint Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
    Cell 146:519-32. 2011
    ..Our findings provide a paradigm for the first step of in vitro gametogenesis...
  8. doi request reprint Stepwise differentiation from naïve state pluripotent stem cells to functional primordial germ cells through an epiblast-like state
    Katsuhiko Hayashi
    Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Methods Mol Biol 1074:175-83. 2013
    ..Here, we describe the culture method of a stepwise differentiation from pluripotent stem cells to functional PGCs...