Kosuke Hashimoto

Summary

Affiliation: Kyoto University
Country: Japan

Publications

  1. ncbi request reprint KEGG as a glycome informatics resource
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Glycobiology 16:63R-70R. 2006
  2. ncbi request reprint The repertoire of desaturases for unsaturated fatty acid synthesis in 397 genomes
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 17:173-83. 2006
  3. ncbi request reprint A global representation of the carbohydrate structures: a tool for the analysis of glycan
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 16:214-22. 2005
  4. ncbi request reprint The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    J Lipid Res 49:183-91. 2008
  5. doi request reprint Comprehensive analysis of glycosyltransferases in eukaryotic genomes for structural and functional characterization of glycans
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Carbohydr Res 344:881-7. 2009
  6. ncbi request reprint An improved scoring scheme for predicting glycan structures from gene expression data
    Akitsugu Suga
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 18:237-46. 2007
  7. ncbi request reprint Prediction of glycan structures from gene expression data based on glycosyltransferase reactions
    Shin Kawano
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Bioinformatics 21:3976-82. 2005
  8. doi request reprint Mining significant tree patterns in carbohydrate sugar chains
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji 611 0011, Japan
    Bioinformatics 24:i167-73. 2008
  9. ncbi request reprint Extraction of species-specific glycan substructures
    Yoshiyuki Hizukuri
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 15:69-81. 2004

Detail Information

Publications9

  1. ncbi request reprint KEGG as a glycome informatics resource
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Glycobiology 16:63R-70R. 2006
    ..In all the KEGG resources, various objects including KEGG pathways, chemical compounds, as well as carbohydrate structures are commonly represented as graphs, which are widely studied and utilized in the computer science field...
  2. ncbi request reprint The repertoire of desaturases for unsaturated fatty acid synthesis in 397 genomes
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 17:173-83. 2006
    ..In this study, we performed a systematic analysis of fatty acid desaturases found in the genomic data of 397 organisms. We obtained a set of desaturases clustered by regioselectivity using a hierarchal clustering analysis...
  3. ncbi request reprint A global representation of the carbohydrate structures: a tool for the analysis of glycan
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 16:214-22. 2005
    ..These resources are available at http://www.genome.jp/kegg/glycan/...
  4. ncbi request reprint The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    J Lipid Res 49:183-91. 2008
    ..This study provides an example of a potent strategy to bridge the gap from genomic knowledge to chemical knowledge...
  5. doi request reprint Comprehensive analysis of glycosyltransferases in eukaryotic genomes for structural and functional characterization of glycans
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Carbohydr Res 344:881-7. 2009
    ..Our findings suggest that universality and diversity of glycans originate from two types of evolution of glycosyltransferase families, namely conserved families with few paralogs and diverged families with many paralogs...
  6. ncbi request reprint An improved scoring scheme for predicting glycan structures from gene expression data
    Akitsugu Suga
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 18:237-46. 2007
    ....
  7. ncbi request reprint Prediction of glycan structures from gene expression data based on glycosyltransferase reactions
    Shin Kawano
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto 611 0011, Japan
    Bioinformatics 21:3976-82. 2005
    ..Using expression profiles from the human carcinoma cell, glycan structures with sialic acid and sialyl Lewis X epitope were predicted, which corresponded well with experimental results...
  8. doi request reprint Mining significant tree patterns in carbohydrate sugar chains
    Kosuke Hashimoto
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji 611 0011, Japan
    Bioinformatics 24:i167-73. 2008
    ..Finding these glycan tree motifs is an important issue, but there have been no computational methods to capture these motifs efficiently...
  9. ncbi request reprint Extraction of species-specific glycan substructures
    Yoshiyuki Hizukuri
    Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611 0011, Japan
    Genome Inform 15:69-81. 2004
    ..We confirmed that the characteristic substructures extracted by our method correspond to the substructures which are known as the species-specific sugar chain of gamma-glutamyltranspeptidases in the kidney...