Tetsuo Shiohara

Summary

Affiliation: Kyorin University
Country: Japan

Publications

  1. ncbi request reprint In vivo evidence for close association of CLA expression and E-selectin binding by T cells in the inflamed skin
    Yuichi Teraki
    J Dermatol Sci 36:63-5. 2004
  2. ncbi request reprint [Drug allergy--the pathogenesis and diagnostic assessment]
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine
    Arerugi 56:649-54. 2007
  3. pmc Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis families
    Hisako Enomoto
    Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan
    BMC Dermatol 7:5. 2007
  4. ncbi request reprint T-cell dynamics of inflammatory skin diseases
    Tetsuo Shiohara
    Department of Dermatology Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Expert Rev Clin Immunol 1:357-68. 2005
  5. ncbi request reprint The immunological basis of lichenoid tissue reaction
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Autoimmun Rev 4:236-41. 2005
  6. ncbi request reprint A complex interaction between drug allergy and viral infection
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Clin Rev Allergy Immunol 33:124-33. 2007
  7. ncbi request reprint [The pathomechanisms and treatment of atopic dermatitis]
    Tetsuo Shiohara
    Department of Dermatology Kyorin University School of Medicine
    Arerugi 55:777-80. 2006
  8. ncbi request reprint Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Allergol Int 55:1-8. 2006
  9. ncbi request reprint Fixed drug eruption: a disease mediated by self-inflicted responses of intraepidermal T cells
    Tetsuo Shiohara
    Kyorin University School of Medicine, 6 20 2, Shinkawa, Mitaka, Tokyo, Japan
    Eur J Dermatol 17:201-8. 2007
  10. doi request reprint Pathomechanisms of lichen planus autoimmunity elicited by cross-reactive T cells
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Curr Dir Autoimmun 10:206-26. 2008

Collaborators

Detail Information

Publications64

  1. ncbi request reprint In vivo evidence for close association of CLA expression and E-selectin binding by T cells in the inflamed skin
    Yuichi Teraki
    J Dermatol Sci 36:63-5. 2004
  2. ncbi request reprint [Drug allergy--the pathogenesis and diagnostic assessment]
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine
    Arerugi 56:649-54. 2007
  3. pmc Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis families
    Hisako Enomoto
    Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan
    BMC Dermatol 7:5. 2007
    ..The aim of this study was to identify chromosome regions linked to atopic dermatitis in a Japanese population...
  4. ncbi request reprint T-cell dynamics of inflammatory skin diseases
    Tetsuo Shiohara
    Department of Dermatology Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Expert Rev Clin Immunol 1:357-68. 2005
    ..It should also be appreciated that T-cell recruitment to the skin is critical for host defense and that no definitive means exist to distinguish protective regulatory T-cells from pathogenic T-cells...
  5. ncbi request reprint The immunological basis of lichenoid tissue reaction
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Autoimmun Rev 4:236-41. 2005
    ..Once cross-reacted with exogenous stimuli, such as drug or self-antigens, however, they would become effectors of epidermal damage as seen in various lichenoid skin diseases...
  6. ncbi request reprint A complex interaction between drug allergy and viral infection
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Clin Rev Allergy Immunol 33:124-33. 2007
    ..Our results indicate the importance of recognizing DIHS and other drug rashes associated with viral infections at risk of eventually developing autoimmune diseases...
  7. ncbi request reprint [The pathomechanisms and treatment of atopic dermatitis]
    Tetsuo Shiohara
    Department of Dermatology Kyorin University School of Medicine
    Arerugi 55:777-80. 2006
  8. ncbi request reprint Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Allergol Int 55:1-8. 2006
    ..This review includes discussion of the pathomechanism, the clinical symptoms, laboratory findings, pathological findings and therapy...
  9. ncbi request reprint Fixed drug eruption: a disease mediated by self-inflicted responses of intraepidermal T cells
    Tetsuo Shiohara
    Kyorin University School of Medicine, 6 20 2, Shinkawa, Mitaka, Tokyo, Japan
    Eur J Dermatol 17:201-8. 2007
    ..In this review, we ask how they arise and how they cause epidermal injuries, which present with a wide spectrum of clinical manifestations and are often mistaken as signs of other skin disease...
  10. doi request reprint Pathomechanisms of lichen planus autoimmunity elicited by cross-reactive T cells
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Curr Dir Autoimmun 10:206-26. 2008
    ....
  11. ncbi request reprint Animal models for atopic dermatitis: are they relevant to human disease?
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    J Dermatol Sci 36:1-9. 2004
    ..Although these mice all have significant disadvantages, it is important to review the current literature on the models in the hope that one may identify useful areas for investigation...
  12. ncbi request reprint Pathophysiology of fixed drug eruption: the role of skin-resident T cells
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Curr Opin Allergy Clin Immunol 2:317-23. 2002
    ..The focus of this review is on how intra-epidermal T cells originally evolved to protect tissue integrity can exert an opposite action that is deleterious to the host...
  13. pmc Direct evidence for interferon-gamma production by effector-memory-type intraepidermal T cells residing at an effector site of immunopathology in fixed drug eruption
    Yoshiko Mizukawa
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Am J Pathol 161:1337-47. 2002
    ..This study provides the first in situ description of the detrimental effects specifically mediated by effector-memory T cells residing at the effector site of immunopathology...
  14. ncbi request reprint Immunohistochemical detection of skin-homing T cells expressing fucosyltransferase VII (Fuc-TVII) in vitro and in situ
    Y Mizukawa
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Lab Invest 81:771-3. 2001
    ..This mAb would serve as a valuable tool for selectively identifying a novel subset of skin "homing" T cells that are not detected by the conventional method because of the lack of CLA expression...
  15. ncbi request reprint Fucosyltransferase VII-positive, skin-homing T cells in the blood and skin lesions of atopic dermatitis patients
    Yoshiko Mizukawa
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Exp Dermatol 17:170-6. 2008
    ..Our data indicate the clinical importance of identifying skin-homing T cells with the potent capacity to migrate into the skin by analysing their Fuc-TVII expression and E-selectin binding ability in patients with AD...
  16. doi request reprint Pathological role of regulatory T cells in the initiation and maintenance of eczema herpeticum lesions
    Ryo Takahashi
    Division of Flow Cytometry, Kyorin University Graduate School of Medicine, Mitaka, Tokyo 181 8611, Japan
    J Immunol 192:969-78. 2014
    ....
  17. ncbi request reprint In vitro differentiation from naive to mature E-selectin binding CD4 T cells: acquisition of skin-homing properties occurs independently of cutaneous lymphocyte antigen expression
    Ryo Takahashi
    Division of Flow Cytometry, Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Immunol 171:5769-77. 2003
    ..Immunofluorescence and confocal microscopy studies of these T cells confirm that most E-selectin ligands were found independently of CLA expression...
  18. doi request reprint Short- and long-term outcomes of 34 patients with drug-induced hypersensitivity syndrome in a single institution
    Yukiko Ushigome
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Am Acad Dermatol 68:721-8. 2013
    ..Although recent reports have documented the development of autoimmune disease after complete resolution of DIHS/DRESS, relatively little is known about long-term outcomes after complete resolution of the disease...
  19. doi request reprint Drug-induced hypersensitivity syndrome: recent advances in the diagnosis, pathogenesis and management
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Chem Immunol Allergy 97:122-38. 2012
    ..Although systemic corticosteroids are the mainstay of treatment, it remains to be determined whether this treatment is beneficial from a viewpoint of disease outcome and sequelae...
  20. ncbi request reprint Drug-induced hypersensitivity syndrome due to mexiletine hydrochloride associated with reactivation of human herpesvirus 7
    Akiko Yagami
    Department of Dermatology, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan
    Dermatology 213:341-4. 2006
    ..All samples, however, were found to contain HHV-7 DNA. Reactivation of HHV-7 could be responsible for drug-induced hypersensitivity syndrome...
  21. doi request reprint Visceral involvements and long-term sequelae in drug-induced hypersensitivity syndrome
    Yoko Kano
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa Mitaka, Tokyo 181 8611, Japan
    Med Clin North Am 94:743-59, xi. 2010
    ..The severity of DIHS is determined by the degree of visceral involvement. Autoimmune diseases also develop several months to years after the apparent clinical resolution of DIHS...
  22. doi request reprint Relationship between cytomegalovirus reactivation and dermatomyositis
    Yuka Kanetaka
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Eur J Dermatol 21:248-53. 2011
    ..Furthermore, our study shows that a reduction in platelets, serum globulin and IgG levels during the course of DM may be useful predictive parameters for CMV reactivation in patients with DM...
  23. doi request reprint Fixed drug eruption: pathogenesis and diagnostic tests
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Curr Opin Allergy Clin Immunol 9:316-21. 2009
    ..In this review, we focus on how the presence of intraepidermal CD8+T cells resident in the fixed drug eruption lesions can provide exciting new clues to our understanding of pathomechanisms of inflammatory skin diseases...
  24. ncbi request reprint Non-steroidal anti-inflammatory drugs selectively inhibit cytokine production by NK cells and gamma delta T cells
    Miyuki Inaoka
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Exp Dermatol 15:981-90. 2006
    ..Our results provide a mechanism to explain the deleterious effects of NSAIDs on clinical symptoms of viral infections and allergic diseases and suggest more targeted use depending on the type of disease...
  25. doi request reprint The variable clinical picture of drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms in relation to the eliciting drug
    Yoko Kano
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa Mitaka, Tokyo 181 8611, Japan
    Immunol Allergy Clin North Am 29:481-501. 2009
    ..A better understanding of the interplay in the development of DIHS/DRESS has implications for safer and more efficient treatment of this syndrome...
  26. ncbi request reprint NK cells and gamma delta+ T cells are phenotypically and functionally defective due to preferential apoptosis in patients with atopic dermatitis
    Michie Katsuta
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Immunol 176:7736-44. 2006
    ....
  27. ncbi request reprint Fixed drug eruption: a prototypic disorder mediated by effector memory T cells
    Yoshiko Mizukawa
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Curr Allergy Asthma Rep 9:71-7. 2009
    ..This review focuses on how these T cells are generated, retained in the epidermis, and activated to cause epidermal damage...
  28. doi request reprint Defective regulatory T cells in patients with severe drug eruptions: timing of the dysfunction is associated with the pathological phenotype and outcome
    Ryo Takahashi
    Division of Flow Cytometry, Kyorin University Graduate School of Medicine, Mitaka, Tokyo, Japan
    J Immunol 182:8071-9. 2009
    ....
  29. ncbi request reprint Expansion of IL-10-producing CD4+ and CD8+ T cells in fixed drug eruption
    Yuichi Teraki
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Dermatology 213:83-7. 2006
    ..A severe form of fixed drug eruption (FDE) clinically and histologically mimics toxic epidermal necrolysis (TEN) but, unlike TEN, resolves spontaneously upon withdrawal of the causative drug...
  30. ncbi request reprint Association between anticonvulsant hypersensitivity syndrome and human herpesvirus 6 reactivation and hypogammaglobulinemia
    Yoko Kano
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Arch Dermatol 140:183-8. 2004
    ..The identification of predisposing factors is clearly needed to predict the incidence and outcome of AHS; attention has recently been focused on reactivation of human herpesvirus 6 (HHV-6)...
  31. ncbi request reprint IFN-gamma-producing effector CD8+ T cells and IL-10-producing regulatory CD4+ T cells in fixed drug eruption
    Yuichi Teraki
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    J Allergy Clin Immunol 112:609-15. 2003
    ....
  32. ncbi request reprint Selective impairment of Toll-like receptor 2-mediated proinflammatory cytokine production by monocytes from patients with atopic dermatitis
    Habib Hasannejad
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Allergy Clin Immunol 120:69-75. 2007
    ..The skin of patients with atopic dermatitis (AD) exhibits a striking susceptibility to infection with gram-positive bacteria and herpes simplex virus (HSV), which are known to stimulate Toll-like receptor (TLR) 2...
  33. ncbi request reprint Virus reactivation and intravenous immunoglobulin (IVIG) therapy of drug-induced hypersensitivity syndrome
    Yoko Kano
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa Mitaka, Tokyo 181 8611, Japan
    Toxicology 209:165-7. 2005
    ..Although the pathomechanism of IVIG treatment in patients with DIHS remains unknown, the therapeutic effects of IVIG could be dependent, in part, on functional capabilities of anti-virus IgG contained in IVIG...
  34. doi request reprint Increased susceptibility to cutaneous viral infections in atopic dermatitis: the roles of regulatory T cells and innate immune defects
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Curr Probl Dermatol 41:125-35. 2011
    ..Here we provide several potential explanations for why AD patients are at greater risk for eczema molluscatum...
  35. doi request reprint A syringotropic variant of cutaneous sarcoidosis: presentation of 3 cases exhibiting defective sweating responses
    Jun Hayakawa
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Am Acad Dermatol 68:1016-21. 2013
    ....
  36. doi request reprint Fixed drug eruption: the dark side of activation of intraepidermal CD8+ T cells uniquely specialized to mediate protective immunity
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Chem Immunol Allergy 97:106-21. 2012
    ....
  37. doi request reprint Cytomegalovirus disease during severe drug eruptions: report of 2 cases and retrospective study of 18 patients with drug-induced hypersensitivity syndrome
    Yusuke Asano
    Department of Dermatology, Kyorin University School of Medicine, 6 20 2 Shinkawa Mitaka, Tokyo 181 8611, Japan
    Arch Dermatol 145:1030-6. 2009
    ..Cutaneous lesions, albeit rare, occur as late systemic manifestations of CMV infections and are usually fatal...
  38. doi request reprint Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice
    Masanobu Nanno
    Yakult Central Institute for Microbiological Research, Tokyo, Japan
    Gastroenterology 134:481-90. 2008
    ..Interestingly, there is a significant increase in gammadelta T cells in the inflamed mucosa of patients with ulcerative colitis (UC). However, the role of gammadelta T cells in chronic colitis has not been fully identified...
  39. doi request reprint Efficacy of plasmapheresis for the treatment of severe toxic epidermal necrolysis: Is cytokine expression analysis useful in predicting its therapeutic efficacy?
    Yoko M Narita
    Department of Dermatology, Kyorin University, Tokyo, Japan
    J Dermatol 38:236-45. 2011
    ..At present, PP is a much more effective option for treatment of severe and/or recalcitrant TEN than any other treatment, such as pulsed corticosteroids and i.v. immunoglobulin...
  40. doi request reprint Viral connection between drug rashes and autoimmune diseases: how autoimmune responses are generated after resolution of drug rashes
    Noriko Aota
    Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Autoimmun Rev 8:488-94. 2009
    ..Patients with DIHS need close monitoring because of possible progression to autoimmune diseases even after the complete resolution...
  41. ncbi request reprint Successful desensitization to fixed drug eruption: the presence of CD25+CD4+ T cells in the epidermis of fixed drug eruption lesions may be involved in the induction of desensitization
    Yuichi Teraki
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Dermatology 209:29-32. 2004
    ..Desensitization is a unique approach for the management of drug eruption, which has been reported to be effective in treating FDE. However, the mechanisms underlying desensitization to FDE are quite unknown...
  42. ncbi request reprint Inhibitory activity of CX-659S, a novel diaminouracil derivative, against the rebound phenomenon following withdrawal of corticosteroid therapy for chronic contact hypersensitivity responses
    Yoshifumi Inoue
    Pharmaceuticals and Biotechnology Laboratory, Japan Energy Corporation, Toda, Saitama, Japan
    Int Arch Allergy Immunol 131:143-52. 2003
    ..The purpose of this study was to assess whether CX- 659S inhibits the rebound phenomenon after discontinuation of chronic treatment with prednisolone in a chronic CHR model in mice...
  43. doi request reprint Recognition of immune reconstitution syndrome necessary for better management of patients with severe drug eruptions and those under immunosuppressive therapy
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Allergol Int 59:333-43. 2010
    ....
  44. ncbi request reprint HIV seronegative eosinophilic pustular folliculitis successfully treated with metronidazole
    Miyuki Inaoka
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Am Acad Dermatol 46:S153-5. 2002
    ..Treatment with metronidazole resulted in complete clearance of the lesion...
  45. ncbi request reprint Trauma-localized fixed drug eruption: involvement of burn scars, insect bites and venipuncture sites
    Yoshiko Mizukawa
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Dermatology 205:159-61. 2002
    ..These 'trauma-localized' FDE lesions are helpful for our understanding of the mechanisms of FDE and other skin diseases, which often appear in their particular areas of predilection, a finding known as 'recall phenomenon'...
  46. ncbi request reprint gammadelta T cells: firefighters or fire boosters in the front lines of inflammatory responses
    Masanobu Nanno
    Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan
    Immunol Rev 215:103-13. 2007
    ..Taken together, in addition to the homeostatic regulation of epithelial tissues, gammadelta T cells appear to play a pivotal role in the modification of inflammatory responses induced in many organs containing epithelia...
  47. ncbi request reprint Are viral infections responsible for the development of drug-induced hypersensitivity syndrome as well as graft-versus-host diseases?
    Tetsuo Shiohara
    Dermatology 210:259-60. 2005
  48. ncbi request reprint Sequential reactivation of herpesvirus in drug-induced hypersensitivity syndrome
    Yoko Kano
    Acta Derm Venereol 84:484-5. 2004
  49. ncbi request reprint [Limbic encephalitis associated with drug-induced hypersensitivity syndrome due to phenobarbital--a case report]
    Takao Ito
    Department of Neurology, School of Medicine, Kyorin University
    Rinsho Shinkeigaku 45:495-501. 2005
    ....
  50. ncbi request reprint [Drug eruption--current concepts]
    Tetsuo Shiohara
    Kyorin University School of Medicine
    Arerugi 51:469-72. 2002
  51. pmc Evidence for reactivation of human herpesvirus 6 in generalized lymphadenopathy in a patient with drug-induced hypersensitivity syndrome
    Takeshi Saraya
    Department of Respiratory Medicine, Kyorin University School of Medicine, Tokyo, Japan
    J Clin Microbiol 51:1979-82. 2013
    ..This case clearly demonstrates that appropriate pathological evaluation of lymphadenopathy for drug-induced hypersensitivity syndrome, which mimics malignant lymphoma in clinical, radiological, and pathological findings, is required...
  52. ncbi request reprint Lichen amyloidosus associated with Kimura's disease: successful treatment with cyclosporine
    Yuichi Teraki
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Dermatology 204:133-5. 2002
    ..Although Kimura's disease and lichen amyloidosus are both rare distinct entities, to our knowledge, 11 cases of association of Kimura's disease and lichen amyloidosus have been described previously...
  53. doi request reprint Lichen planus occurring after influenza vaccination: report of three cases and review of the literature
    Noriko Aota Sato
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Dermatology 221:296-9. 2010
    ..We suggest that a history of recent vaccination should be sought in all patients presenting with linear LP...
  54. ncbi request reprint Fixed drug eruption: easily overlooked but needing new respect
    Tetsuo Shiohara
    Dermatology 205:103-4. 2002
  55. ncbi request reprint [Early diagnosis and management of drug-induced disorders. 4) Severe drug eruptions associated with viral re-activation and multiple organ lesions]
    Tetsuo Shiohara
    Nihon Naika Gakkai Zasshi 96:1883-7. 2007
  56. ncbi request reprint Atypical bullous disease showing features of both erythema multiforme and bullous pemhigoid
    Kazuhito Hayakawa
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Acta Derm Venereol 82:196-9. 2002
    ....
  57. doi request reprint Defective sweating responses in atopic dermatitis
    Tetsuo Shiohara
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    Curr Probl Dermatol 41:68-79. 2011
    ..These results indicate that the sweat may be retained in the lumen or pour into the dermal tissues, thereby causing inflammation. Thus, chronic inflammation in AD may be caused in part by a dysfunction of the sweat delivery system...
  58. ncbi request reprint Mycoplasma pneumoniae infection-induced erythema nodosum, anaphylactoid purpura, and acute urticaria in 3 people in a single family
    Yoko Kano
    Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
    J Am Acad Dermatol 57:S33-5. 2007
    ..Age-related variations in cutaneous manifestations of M pneumoniae infections can be attributed to the immaturity of the adaptive immunity of a host, as has been suggested in viral infections...
  59. ncbi request reprint Hypogammaglobulinemia as an early sign of drug-induced hypersensitivity syndrome
    Yoko Kano
    J Am Acad Dermatol 55:727-8. 2006
  60. ncbi request reprint Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells
    Hiroyuki Tezuka
    Department of Immunology, Akita University Graduate School of Medicine, Akita 010 8543, Japan
    Nature 448:929-33. 2007
    ..The presence of a naturally occurring TNF-alpha/iNOS-producing dendritic-cell subset may explain the predominance of IgA production in the MALT, critical for gut homeostasis...
  61. ncbi request reprint Recall phenomenon: some skin-resident cells remember previous insults
    Tetsuo Shiohara
    Dermatology 207:127-9. 2003
  62. ncbi request reprint Spontaneous tolerance to terbinafine-induced lichenoid drug eruption
    Yuichi Teraki
    Dermatology 208:81-2. 2004
  63. doi request reprint Atypical cutaneous tuberculosis in a patient with rheumatoid arthritis treated with infliximab
    Yusuke Asano
    Acta Derm Venereol 88:183-4. 2008
  64. ncbi request reprint Two cases of Henoch-Schönlein purpura with transient myocardial ischaemia
    Kazuhito Hayakawa
    Acta Derm Venereol 83:393-4. 2003