Annabelle A Okada

Summary

Affiliation: Kyorin University School of Medicine
Country: Japan

Publications

  1. pmc Two-year outcomes of pro re nata ranibizumab monotherapy for exudative age-related macular degeneration in Japanese patients
    Akiko Yamamoto
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Clin Ophthalmol 7:757-63. 2013
  2. doi request reprint Ancillary testing, diagnostic/classification criteria and severity grading in Behçet disease
    Annabelle A Okada
    Kyorin Eye Center, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Ocul Immunol Inflamm 20:387-93. 2012
  3. doi request reprint Multicenter study of infliximab for refractory uveoretinitis in Behçet disease
    Annabelle A Okada
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Arch Ophthalmol 130:592-8. 2012
  4. doi request reprint Long-term efficacy and safety of ranibizumab administered pro re nata in Japanese patients with neovascular age-related macular degeneration in the EXTEND-I study
    Yasuo Tano
    Department of Ophthalmology, Osaka University Medical School, Osaka, Japan
    Acta Ophthalmol 89:208-17. 2011
  5. doi request reprint Decreased ocular inflammatory attacks and background retinal and disc vascular leakage in patients with Behcet's disease on infliximab therapy
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Br J Ophthalmol 95:1245-50. 2011
  6. doi request reprint Enhanced depth imaging optical coherence tomography of the choroid in Vogt-Koyanagi-Harada disease
    Makiko Nakayama
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Retina 32:2061-9. 2012
  7. doi request reprint High mobility group box protein-1 in experimental autoimmune uveoretinitis
    Takayo Watanabe
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 50:2283-90. 2009
  8. doi request reprint Oral administration of retinoic acid receptor-alpha/beta-specific ligand Am80 suppresses experimental autoimmune uveoretinitis
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 52:1548-56. 2011
  9. pmc Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo, 181 8611 Japan
    Arthritis Res Ther 10:R122. 2008
  10. ncbi request reprint Anti-inflammatory effect of retinoic acid on experimental autoimmune uveoretinitis
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Br J Ophthalmol 94:802-7. 2010

Collaborators

Detail Information

Publications33

  1. pmc Two-year outcomes of pro re nata ranibizumab monotherapy for exudative age-related macular degeneration in Japanese patients
    Akiko Yamamoto
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Clin Ophthalmol 7:757-63. 2013
    ..To describe outcomes of intravitreal ranibizumab using a pro re nata regimen for treatment-naive exudative age-related macular degeneration (AMD), in Japanese patients over the first 2 years...
  2. doi request reprint Ancillary testing, diagnostic/classification criteria and severity grading in Behçet disease
    Annabelle A Okada
    Kyorin Eye Center, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Ocul Immunol Inflamm 20:387-93. 2012
    ..Finally, several grading schemes have been proposed to assess severity of ocular disease and response to treatment...
  3. doi request reprint Multicenter study of infliximab for refractory uveoretinitis in Behçet disease
    Annabelle A Okada
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Arch Ophthalmol 130:592-8. 2012
    ..To describe the effects of infliximab on refractory uveoretinitis in patients with Behçet disease during the first year of treatment...
  4. doi request reprint Long-term efficacy and safety of ranibizumab administered pro re nata in Japanese patients with neovascular age-related macular degeneration in the EXTEND-I study
    Yasuo Tano
    Department of Ophthalmology, Osaka University Medical School, Osaka, Japan
    Acta Ophthalmol 89:208-17. 2011
    ....
  5. doi request reprint Decreased ocular inflammatory attacks and background retinal and disc vascular leakage in patients with Behcet's disease on infliximab therapy
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Br J Ophthalmol 95:1245-50. 2011
    ..To evaluate the efficacy of infliximab treatment in patients with refractory uveoretinitis associated with Behçet's disease...
  6. doi request reprint Enhanced depth imaging optical coherence tomography of the choroid in Vogt-Koyanagi-Harada disease
    Makiko Nakayama
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Retina 32:2061-9. 2012
    ..Our objective was to analyze subfoveal choroidal thickness by EDI-OCT before and after the initiation of high-dose corticosteroid treatment in 8 patients (16 eyes) with new-onset acute Vogt-Koyanagi-Harada (VKH) disease...
  7. doi request reprint High mobility group box protein-1 in experimental autoimmune uveoretinitis
    Takayo Watanabe
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 50:2283-90. 2009
    ..To investigate whether high mobility group box protein (HMGB)-1, acting as a novel proinflammatory cytokine, is involved in experimental autoimmune uveoretinitis (EAU)...
  8. doi request reprint Oral administration of retinoic acid receptor-alpha/beta-specific ligand Am80 suppresses experimental autoimmune uveoretinitis
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 52:1548-56. 2011
    ..To determine whether synthetic retinoic acid receptor (RAR)-α/β-specific agonist Am80 reduces inflammation in experimental autoimmune uveoretinitis (EAU)...
  9. pmc Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo, 181 8611 Japan
    Arthritis Res Ther 10:R122. 2008
    ..The purpose of this study was to determine if oral administration of the interleukin (IL) 12/IL-23 inhibitor, STA-5326, is effective in experimental autoimmune uveoretinitis (EAU)...
  10. ncbi request reprint Anti-inflammatory effect of retinoic acid on experimental autoimmune uveoretinitis
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Br J Ophthalmol 94:802-7. 2010
    ..To determine whether an active metabolite of vitamin A, all-trans retinoic acid (ATRA), reduces inflammation in experimental autoimmune uveoretinitis (EAU)...
  11. ncbi request reprint Long-term results of vitrectomy without laser treatment for macular detachment associated with an optic disc pit
    Akito Hirakata
    Kyorin Eye Center, Department of Ophthalmology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Ophthalmology 112:1430-5. 2005
    ..To evaluate the efficacy of vitrectomy and gas tamponade, without laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with an optic disc pit...
  12. doi request reprint Acute retinal necrosis: factors associated with anatomic and visual outcomes
    Chiharu Iwahashi-Shima
    Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan
    Jpn J Ophthalmol 57:98-103. 2013
    ..To examine the factors associated with anatomic and visual outcomes in Japanese patients with acute retinal necrosis (ARN)...
  13. doi request reprint Vitreous surgery for macular hole in patients with Vogt-Koyanagi-Harada disease
    Izumi Kobayashi
    Kyorin Eye Center, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo, Japan
    Clin Experiment Ophthalmol 36:861-4. 2008
    ..Macular holes have also been reported previously in patients during the convalescent stage of VKH and this communication describes the outcome of two patients who underwent vitreo-retinal surgery for this problem...
  14. doi request reprint Effect of infliximab on gene expression profiling in Behcet's disease
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 52:7681-6. 2011
    ..In this study, the effect of infliximab on gene expression patterns in peripheral blood mononuclear cells of Behçet's disease patients was investigated before and after initiation of infliximab treatment...
  15. ncbi request reprint Changing patterns of intraocular inflammatory disease in Japan
    Toshiko Wakabayashi
    Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan
    Ocul Immunol Inflamm 11:277-86. 2003
    ..We investigated the frequencies and clinical characteristics of Japanese patients with uveitis...
  16. ncbi request reprint Histological effect and protein expression in subthreshold transpupillary thermotherapy in rabbit eyes
    Yoshihiro Morimura
    Department of Ophthalmology, Kyorin University School of Medicine, Mitaka shi, Tokyo, Japan
    Arch Ophthalmol 122:1510-5. 2004
    ..To investigate the histological effect of subthreshold transpupillary thermotherapy (TTT) on the retina...
  17. doi request reprint Clinical features of polypoidal choroidal vasculopathy and visual outcomes in the absence of classic choroidal neovascularization
    Seijo Yamaoka
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Ophthalmologica 224:147-52. 2010
    ..To report on the clinical features of polypoidal choroidal vasculopathy (PCV) and to delineate visual outcomes in the absence of classic choroidal neovascularization (CNV)...
  18. ncbi request reprint Trans-tenon retrobulbar triamcinolone infusion for chronic macular edema in central and branch retinal vein occlusion
    Toshiko Wakabayashi
    Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan
    Retina 24:964-7. 2004
  19. ncbi request reprint [Vitrectomy for endophthalmitis after cataract surgery]
    Kazuhiro Oshitari
    Department of Ophthalmology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka 181 8611, Japan
    Nihon Ganka Gakkai Zasshi 107:590-6. 2003
    ..To identify risk factors of poor visual outcome with vitrectomy for early-onset endophthalmitis after cataract surgery...
  20. ncbi request reprint Bilateral anterior optic neuritis in adult measles infection without encephalomyelitis
    Masami Azuma
    Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan
    Am J Ophthalmol 134:768-9. 2002
    ..To describe anterior optic neuritis in adult measles infection...
  21. ncbi request reprint EXTEND-I: safety and efficacy of ranibizumab in Japanese patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration
    Yasuo Tano
    Department of Ophthalmology, Osaka University Medical School, Japan
    Acta Ophthalmol 88:309-16. 2010
    ..To evaluate the efficacy and safety of intravitreal ranibizumab for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Japanese patients...
  22. ncbi request reprint [Diagnostic value of interleukin-10 and interleukin-6 in the vitreous of intraocular malignant lymphoma patients]
    Akito Hirakata
    Department of Ophthalmology, Kyorin University School of Medicine, Mitaka, Japan
    Nihon Ganka Gakkai Zasshi 108:359-67. 2004
    ..In this study, we evaluated the utility of measuring intravitreal IL-10 and IL-6 concentrations in the diagnosis of intraocular lymphoma...
  23. doi request reprint Frequency and clinical features of intraocular inflammation in Tokyo
    Hiroshi Keino
    Department of Ophthalmology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Clin Experiment Ophthalmol 37:595-601. 2009
    ..To investigate frequencies and clinical features of intraocular inflammation (uveitis) in Tokyo, Japan...
  24. ncbi request reprint [Two cases of treatment for juxtapapillary hemangioma associated with von Hippel-Lindau disease]
    Tsunehiro Saito
    Department of Ophthalmology, Kyorin University School of Medicine, Japan
    Nihon Ganka Gakkai Zasshi 118:33-9. 2014
    ..We compared therapeutic outcomes in two cases of juxtapapillary capillary hemangiomas associated with von Hippel-Lindau disease...
  25. doi request reprint Expression of inhibin alpha by stromal cells of retinal angiomas excised from a patient with von Hippel-Lindau disease
    Akiko Miyazawa
    Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 53:501-5. 2009
    ..To report the results of immunohistochemical analyses of a retinal angioma obtained from a patient with von Hippel-Lindau (VHL) disease...
  26. ncbi request reprint Long-term complications of hydrogel buckles
    Kazuhiro Oshitari
    Kyorin Eye Center, Tokyo, Japan
    Retina 23:257-61. 2003
    ..To investigate long-term complications of hydrogel buckles used in scleral buckling surgery for retinal detachment...
  27. ncbi request reprint [Sweet syndrome presenting as orbital cellulitis]
    Kazuhiro Oshitari
    Department of Ophthalmology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka 181 8611, Japan
    Nihon Ganka Gakkai Zasshi 108:162-5. 2004
    ..A case of Sweet syndrome mimicking orbital cellulitis is reported...
  28. ncbi request reprint Behçet's disease: general concepts and recent advances
    Annabelle A Okada
    Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Curr Opin Ophthalmol 17:551-6. 2006
    ..To summarize general concepts of Behçet's disease, as well as present recent scientific developments in delineating the pathogenesis and treatment of this disorder...
  29. ncbi request reprint Subretinal hemorrhages after blunt trauma in pseudoxanthoma elasticum
    Norihisa Soutome
    Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan
    Retina 27:807-8. 2007
  30. ncbi request reprint Tuberculin skin testing in uveitis patients and treatment of presumed intraocular tuberculosis in Japan
    Yoshihiro Morimura
    Kyorin Eye Center, Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan
    Ophthalmology 109:851-7. 2002
    ..To evaluate the results of tuberculin skin testing in Japanese patients with intraocular inflammation and to assess the outcome of treatment for presumed intraocular tuberculosis in selected patients...
  31. ncbi request reprint Immunomodulatory therapy for ocular inflammatory disease: a basic manual and review of the literature
    Annabelle A Okada
    Department of Ophthalmology, Kyorin University School of Medicine, 6 20 2, Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Ocul Immunol Inflamm 13:335-51. 2005
    ..This article reviews and summarizes the evidence for IMT agent use in the treatment of various forms of ocular inflammation...
  32. ncbi request reprint ABCA4 gene mutations in Japanese patients with Stargardt disease and retinitis pigmentosa
    Takehiro Fukui
    Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan
    Invest Ophthalmol Vis Sci 43:2819-24. 2002
    ..To evaluate photoreceptor cell-specific adenosine triphosphate (ATP)-binding cassette transporter (ABCA4) gene mutations in Japanese patients with Stargardt disease (STGD) and the correlation of these mutations to clinical phenotypes...
  33. ncbi request reprint Oral administration of interferon-beta suppresses experimental autoimmune uveoretinitis
    Jun Suzuki
    Department of Ophthalmology, Tokyo Medical University Hospital, 6 7 1 Nishishinjuku, Shinjuku ku, Tokyo 160 0023, Japan
    Graefes Arch Clin Exp Ophthalmol 240:314-21. 2002
    ..This study examined whether oral administration of IFN-beta is capable of modulating inflammation in experimental autoimmune uveoretinitis (EAU)...