Y Nagao

Summary

Affiliation: Kurume University School of Medicine
Country: Japan

Publications

  1. pmc Effects and outcomes of interferon treatment in Japanese hepatitis C patients
    Kazumi Yamasaki
    Narao Medical Center, Shinkamigoto, Japan
    BMC Gastroenterol 12:139. 2012
  2. pmc Effect of branched-chain amino acid-enriched nutritional supplementation on interferon therapy in Japanese patients with chronic hepatitis C virus infection: a retrospective study
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Virol J 9:282. 2012
  3. pmc Candidiasis and other oral mucosal lesions during and after interferon therapy for HCV-related chronic liver diseases
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    BMC Gastroenterol 12:155. 2012
  4. pmc Analysis of the factors motivating HCV-infected patients to accept interferon therapy
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, 830 0011, Japan
    BMC Res Notes 5:470. 2012
  5. pmc A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    BMC Gastroenterol 12:31. 2012
  6. ncbi request reprint Epidemiological survey of oral lichen planus among HCV-infected inhabitants in a town in Hiroshima Prefecture in Japan from 2000 to 2003
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Oncol Rep 18:1177-81. 2007
  7. doi request reprint Graves' ophthalmopathy and tongue cancer complicated by peg-interferon α-2b and ribavirin therapy for chronic hepatitis C: A case report and review of the literature
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Mol Med Report 1:625-31. 2008
  8. doi request reprint Insulin resistance and lichen planus in patients with HCV-infectious liver diseases
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Asahi machi, Kurume, Fukuoka, Japan
    J Gastroenterol Hepatol 23:580-5. 2008
  9. ncbi request reprint HBV and HCV infection in Japanese dental care workers
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 21:791-9. 2008
  10. pmc Serum albumin and mortality risk in a hyperendemic area of HCV infection in Japan
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Virol J 7:375. 2010

Collaborators

Detail Information

Publications37

  1. pmc Effects and outcomes of interferon treatment in Japanese hepatitis C patients
    Kazumi Yamasaki
    Narao Medical Center, Shinkamigoto, Japan
    BMC Gastroenterol 12:139. 2012
    ..To clarify the long-term prognosis of HCV-positive residents of an isolated Japanese island and prospectively investigate the effects of IFN treatment in comparison with the HCV-negative general population...
  2. pmc Effect of branched-chain amino acid-enriched nutritional supplementation on interferon therapy in Japanese patients with chronic hepatitis C virus infection: a retrospective study
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Virol J 9:282. 2012
    ....
  3. pmc Candidiasis and other oral mucosal lesions during and after interferon therapy for HCV-related chronic liver diseases
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    BMC Gastroenterol 12:155. 2012
    ..The aim of this study was to evaluate the occurrence of oral candidiasis, other mucosal lesions, and xerostomia during interferon (IFN) therapy for HCV infection...
  4. pmc Analysis of the factors motivating HCV-infected patients to accept interferon therapy
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, 830 0011, Japan
    BMC Res Notes 5:470. 2012
    ..The aims of this study were to analyze factors motivating the acceptance of interferon (IFN) therapy and to clarify the prevalence of oral mucosal diseases in hepatitis C virus (HCV)-infected Japanese patients treated with IFN...
  5. pmc A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    BMC Gastroenterol 12:31. 2012
    ....
  6. ncbi request reprint Epidemiological survey of oral lichen planus among HCV-infected inhabitants in a town in Hiroshima Prefecture in Japan from 2000 to 2003
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Oncol Rep 18:1177-81. 2007
    ..Screening for extrahepatic manifestations should be conducted in patients with risk factors for HCV infection...
  7. doi request reprint Graves' ophthalmopathy and tongue cancer complicated by peg-interferon α-2b and ribavirin therapy for chronic hepatitis C: A case report and review of the literature
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Mol Med Report 1:625-31. 2008
    ..In conclusion, it is necessary to clinically examine organs other than the liver in patients with HCV infection...
  8. doi request reprint Insulin resistance and lichen planus in patients with HCV-infectious liver diseases
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Asahi machi, Kurume, Fukuoka, Japan
    J Gastroenterol Hepatol 23:580-5. 2008
    ..The aims of the present study were to examine the incidence of extrahepatic manifestations including lichen planus in HCV-infected patients and to evaluate the relationship between lichen planus and insulin resistance...
  9. ncbi request reprint HBV and HCV infection in Japanese dental care workers
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 21:791-9. 2008
    ..HBV vaccination should be made compulsory for all dental care workers who handle sharp instruments...
  10. pmc Serum albumin and mortality risk in a hyperendemic area of HCV infection in Japan
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Virol J 7:375. 2010
    ..This follow-up study determined, through a period of 12 years, whether serum albumin levels impact on the life prognosis of the residents of X town...
  11. pmc Dental problems delaying the initiation of interferon therapy for HCV-infected patients
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Virol J 7:192. 2010
    ..This study determined whether dental problems delayed the initiation of IFN therapy for hepatitis C virus (HCV)-infected patients...
  12. ncbi request reprint Analysis of factors interfering with the acceptance of interferon therapy by HCV-infected patients
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Med Sci Monit 14:PI45-52. 2008
    ..However, IFN therapy is not well-implemented in Japan. The present study was conducted to analyze factors preventing the implementation of IFN therapy...
  13. ncbi request reprint High incidence of multiple primary carcinomas in HCV-infected patients with oral squamous cell carcinoma
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Med Sci Monit 15:CR453-9. 2009
    ..Oral cancer is one of them. We investigated the association among oral squamous cell carcinoma (OSCC), multiple primary cancers (MPCs), insulin resistance and HCV infection...
  14. ncbi request reprint Knowledge of Vibrio vulnificus infection among Japanese patients with liver diseases: a prospective multicenter study
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Med Sci Monit 15:PH115-120. 2009
    ..The present study was conducted to assess the level of knowledge of patients with liver disease regarding V. vulnificus infection...
  15. pmc Effect of oral care gel on the quality of life for oral lichen planus in patients with chronic HCV infection
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka 830 0011, Japan
    Virol J 8:348. 2011
    ..In addition, OLP may be associated with HCV-related liver disease.We investigated the visual analogue scale (VAS) and effects of oral care gel, REFRECARE-H®, on patients with OLP associated with HCV infection...
  16. ncbi request reprint Aminofeel improves the sensitivity to taste in patients with HCV-infected liver disease
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Med Sci Monit 16:PI7-12. 2010
    ..We investigated the effects of a supplement enriched with branched-chain amino acids (BCAA) (Aminofeel) on sensitivity to different tastes in patients with hepatitis C virus (HCV) infected liver disease...
  17. ncbi request reprint Extrahepatic manifestations and insulin resistance in an HCV hyperendemic area
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Asahi machi, Kurume 830 0011, Japan
    Int J Mol Med 16:291-6. 2005
    ..03, p = 0.01, respectively). Insulin resistance induces HCV infection, which causes an increase in the incidence of extrahepatic manifestations in HCV-infected individuals...
  18. ncbi request reprint Exacerbation of oral erosive lichen planus by combination of interferon and ribavirin therapy for chronic hepatitis C
    Yumiko Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 15:237-41. 2005
    ..Aminotransferase levels were decreased, but serum HCV RNA had not disappeared. Caution should be exercised when IFN or ribavirin therapy is given to chronic hepatitis C patients with prior erosive OLP...
  19. ncbi request reprint High prevalence of anticardiolipin antibodies in patients with HCV-associated oral lichen planus
    Y Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 9:293-7. 2002
    ..The findings of the present study showed a high prevalence of IgG and IgM aCL in the serum of patients with HCV infectious diseases. A positive factor for aCL was determined by age, sex, the presence of OLP, and HCV infection...
  20. ncbi request reprint The possible intraspousal transmission of HCV in terms of lichen planus
    Y Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Int J Mol Med 10:569-73. 2002
    ..Clinicians should follow the OLP patients with sufficient attention to the presence of extraoral manifestations. These data may suggest the occurrence of intraspousal transmission of HCV through erosive vulvar LP...
  21. ncbi request reprint A cohort study of chronic liver disease in an HCV hyperendemic area of Japan: a prospective analysis for 12 years
    Y Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 13:257-65. 2004
    ..Furthermore, persistent HCV carriers should receive therapy for suppression of the development of HCC. The eradication of HCC should be considered a national goal...
  22. ncbi request reprint Incidence of Sjögren's syndrome in Japanese patients with hepatitis C virus infection
    Yumiko Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    J Gastroenterol Hepatol 18:258-66. 2003
    ..The purpose of the present study was to evaluate Sjögren's syndrome (SS) and lichen planus (LP) involvement, which are various extrahepatic manifestations in patients with liver diseases related to hepatitis B virus (HBV) or HCV...
  23. ncbi request reprint Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Am J Gastroenterol 102:570-6. 2007
    ..The aim of this study is to examine the effects of clearance of HCV on insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate (IRS)1/2, central molecules for insulin signaling...
  24. ncbi request reprint [HCV and extrahepatic manifestations]
    Yumiko Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine
    Nihon Rinsho 62:561-8. 2004
  25. ncbi request reprint Hepatitis C virus and lichen planus
    Yumiko Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    J Gastroenterol Hepatol 19:1101-13. 2004
    ..The present review focuses on lichen planus, one of the major extrahepatic manifestations...
  26. ncbi request reprint Antibody to hepatitis B core antigen is associated with the development of hepatocellular carcinoma in hepatitis C virus-infected persons: a 12-year prospective study
    Kazuo Tanaka
    Second Department of Internal Medicine, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 17:827-32. 2006
    ..Our findings provide clear evidence in a prospective study that presence of anti-HBc, that is, past hepatitis B virus (HBV) infection, is a risk factor for the development of HCC in HCV-infected people...
  27. ncbi request reprint Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Int J Mol Med 22:105-12. 2008
    ..Thus, a BCAA-enriched supplement may be a useful therapeutic agent for decreasing insulin resistance in male patients with chronic viral liver disease...
  28. pmc Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
    Takumi Kawaguchi
    Second Department of Medicine, Kurume University School of Medicine 67 Asahi machi, Kurume 830 0011, Japan
    Am J Pathol 165:1499-508. 2004
    ..In conclusion, HCV infection changes a subset of hepatic molecules regulating glucose metabolism. A possible mechanism is that HCV core-induced SOCS3 promotes proteosomal degradation of IRS1 and IRS2 through ubiquitination...
  29. ncbi request reprint Branched-chain amino acids improve insulin resistance in patients with hepatitis C virus-related liver disease: report of two cases
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Liver Int 27:1287-92. 2007
    ..Thus, BCAAs are a potential therapeutic agent for improving insulin resistance in patients with HCV-related liver disease...
  30. ncbi request reprint Branched-chain amino acid supplementation complements conventional treatment for spontaneous bacterial peritonitis
    Eitaro Taniguchi
    Nutritional Curative Team and Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Dig Dis Sci 51:1057-60. 2006
  31. ncbi request reprint Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area: a pilot study
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 16:109-14. 2005
    ..41 to 37.42). In conclusion, HCV infection potentially has a significant role in the development of type 2 diabetes mellitus at the population level. Further large-scale studies are needed to confirm these preliminary findings...
  32. ncbi request reprint Detection of hepatitis C virus in saliva before and after scaling of dental calculus
    Y Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, 67 Asahimachi, Kurume 830-0011, Japan
    Kansenshogaku Zasshi 74:961-5. 2000
    ..In conclusion, dentists and dental health care workers should be aware of the possibility of HCV infection via contact with serum and saliva during dental practice...
  33. ncbi request reprint Serum levels of IgG to the peptide of HCV1b core at positions 35-44 correlated with persistent infection, while levels of IgG to the peptide of NS5A at positions 2132-2140 correlated with better prognosis in HCV-infected patients
    Yukari Takao
    Department of Immunology, Kurume University School of Medicine, Kurume, Fukuoka 830 0011, Japan
    Med Microbiol Immunol 196:157-64. 2007
    ..These results suggest that sequential measurement of the two Abs together may provide new information for the prediction of prognosis...
  34. ncbi request reprint [HCV or HBV infection self-disclosure to dentists]
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine
    Kansenshogaku Zasshi 82:213-9. 2008
    ..The government should take appropriate measures to encourage and support dentists who use precautions to prevent nosocomial infection...
  35. ncbi request reprint [Survey of hepatitis B and C in students of faculty of dentistry and dental hygienist school]
    Yumiko Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine
    Kansenshogaku Zasshi 78:554-65. 2004
    ..In addition, it is an important problem to spread thoughts of standard precautions for dentistry...
  36. ncbi request reprint The prognosis for life in an HCV hyperendemic area
    Yumiko Nagao
    Gastroenterology 125:628-9. 2003