Akihiko Kawahara

Summary

Affiliation: Kurume University School of Medicine
Country: Japan

Publications

  1. doi request reprint A diagnostic algorithm using EGFR mutation-specific antibodies for rapid response EGFR-TKI treatment in patients with non-small cell lung cancer
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    Lung Cancer 78:39-44. 2012
  2. doi request reprint Salivary duct carcinoma cytologically diagnosed distinctly from salivary gland carcinomas with squamous differentiation
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Japan
    Diagn Cytopathol 36:485-93. 2008
  3. doi request reprint Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume 19107, Japan
    Diagn Cytopathol 38:377-81. 2010
  4. doi request reprint Nuclear β-catenin expression in basal cell adenomas of salivary gland
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    J Oral Pathol Med 40:460-6. 2011
  5. pmc Higher expression of deoxyuridine triphosphatase (dUTPase) may predict the metastasis potential of colorectal cancer
    A Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Japan
    J Clin Pathol 62:364-9. 2009
  6. doi request reprint Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, 67 Asahi Machi, Kurume 830 0011, Japan
    Lung Cancer 74:35-40. 2011
  7. ncbi request reprint Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume 830 0011, Japan
    Oncol Rep 24:405-15. 2010
  8. ncbi request reprint Fine-needle aspiration cytology of basal cell adenoma of the parotid gland: characteristic cytological features and diagnostic pitfalls
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Japan
    Diagn Cytopathol 35:85-90. 2007
  9. ncbi request reprint p63 Expression of clear myoepithelial cells in epithelial-myoepithelial carcinoma of the salivary gland: a useful marker for naked myoepithelial cells in cytology
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Kurume, Japan
    Cancer 105:240-5. 2005
  10. doi request reprint NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer
    Koichi Azuma
    Department of Internal Medicine, Division of Respirology, Neurology, and Rheumatology, Kurume University School of Medicine, Kurume, Japan
    J Thorac Oncol 7:779-89. 2012

Detail Information

Publications60

  1. doi request reprint A diagnostic algorithm using EGFR mutation-specific antibodies for rapid response EGFR-TKI treatment in patients with non-small cell lung cancer
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    Lung Cancer 78:39-44. 2012
    ....
  2. doi request reprint Salivary duct carcinoma cytologically diagnosed distinctly from salivary gland carcinomas with squamous differentiation
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Japan
    Diagn Cytopathol 36:485-93. 2008
    ..001) were effective as SDC-specific markers in immunohistochemistry. An accurate cytological diagnosis of SDC can be determined by immunostaining with AR, GCDFP15, and p63, based on the nuclear findings...
  3. doi request reprint Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume 19107, Japan
    Diagn Cytopathol 38:377-81. 2010
    ....
  4. doi request reprint Nuclear β-catenin expression in basal cell adenomas of salivary gland
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    J Oral Pathol Med 40:460-6. 2011
    ..Our objective was to confirm the nuclear localization of β-catenin in basal cell adenoma and to examine whether nuclear β-catenin expression could be a useful marker in the diagnosis of basal cell adenoma...
  5. pmc Higher expression of deoxyuridine triphosphatase (dUTPase) may predict the metastasis potential of colorectal cancer
    A Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Japan
    J Clin Pathol 62:364-9. 2009
    ..Furthermore, there was a comparison of these expression levels between the primary tumour and the corresponding metastasis...
  6. doi request reprint Identification of non-small-cell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, 67 Asahi Machi, Kurume 830 0011, Japan
    Lung Cancer 74:35-40. 2011
    ..Furthermore, we compared activating EGFR mutations between primary and recurrent NSCLC...
  7. ncbi request reprint Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume 830 0011, Japan
    Oncol Rep 24:405-15. 2010
    ..001), but not diffuse type cancer. TP could be a specific marker enzyme that is expressed in tumor-infiltrating macrophages, being associated with tumor angiogenesis and poor prognosis in patients with intestinal-type gastric cancer...
  8. ncbi request reprint Fine-needle aspiration cytology of basal cell adenoma of the parotid gland: characteristic cytological features and diagnostic pitfalls
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Japan
    Diagn Cytopathol 35:85-90. 2007
    ..Accurate differential cytological diagnosis of BCA is relatively easy to determine the solid type BCA, but is more difficult for cystic type BCA...
  9. ncbi request reprint p63 Expression of clear myoepithelial cells in epithelial-myoepithelial carcinoma of the salivary gland: a useful marker for naked myoepithelial cells in cytology
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Kurume, Japan
    Cancer 105:240-5. 2005
    ..In the current study, the authors analyzed the distribution and visual patterns of p63-positive clear myoepithelial cells in EMC...
  10. doi request reprint NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer
    Koichi Azuma
    Department of Internal Medicine, Division of Respirology, Neurology, and Rheumatology, Kurume University School of Medicine, Kurume, Japan
    J Thorac Oncol 7:779-89. 2012
    ..We investigated how NDRG1/Cap43 could affect tumor growth and angiogenesis in non-small-cell lung cancer (NSCLC) in vivo using an animal experimental model, and also how it could affect tumor angiogenesis and prognosis in NSCLC patients...
  11. doi request reprint Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with a combination of cisplatin/docetaxel and concurrent thoracic irradiation
    Koichi Azuma
    Department of Internal Medicine, Division of Respirology, Neurology, and Rheumatology, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Cancer Chemother Pharmacol 64:565-73. 2009
    ..The expression of excision repair cross-complementation group 1 (ERCC1) is reported to be correlated with resistance to platinum-based drugs. Class III beta-tubulin is reported to be correlated with resistance to taxanes...
  12. ncbi request reprint Expression of IGF-1 and IGF-1R and their relation to clinicopathological factors in colorectal cancer
    Ichitarou Shiratsuchi
    Department of Surgery, Faculty of Medicine, Kurume University, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    Anticancer Res 31:2541-5. 2011
    ..We examined the correlation between expression of IGF-1 and IGF-1R and clinicopathological factors in colorectal cancer...
  13. doi request reprint Molecular diagnosis of activating EGFR mutations in non-small cell lung cancer using mutation-specific antibodies for immunohistochemical analysis
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    Clin Cancer Res 16:3163-70. 2010
    ..We have investigated whether this method detects activating EGFR mutations with sensitivity comparable with direct DNA sequencing, which is used to detect these mutations in NSCLC...
  14. doi request reprint The close correlation between 8-hydroxy-2'-deoxyguanosine and epidermal growth factor receptor activating mutation in non-small cell lung cancer
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume 830 0011, Japan
    Hum Pathol 41:951-9. 2010
    ..Thus, activating mutations of the epidermal growth factor receptor gene in non-small cell lung cancer were closely associated with a decrease in the damage repair process for 8-hydroxy-2'-deoxyguanosine in oxidized DNA...
  15. doi request reprint Comparison of the expression levels of napsin A, thyroid transcription factor-1, and p63 in nonsmall cell lung cancer using cytocentrifuged bronchial brushings
    Emiko Aikawa
    Department of Diagnostic Pathology, Kurume University Hospital, Japan
    Cancer Cytopathol 119:335-45. 2011
    ..The aim of this study was to evaluate the expression levels of Napsin A, thyroid transcription factor-1 (TTF-1), and p63 by immunostaining using CytoRich Red preserved cytocentrifuged bronchial brushings...
  16. doi request reprint Prognostic significance of total lesion glycolysis in patients with advanced non-small cell lung cancer receiving chemotherapy
    Yoshiaki Zaizen
    Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan
    Eur J Radiol 81:4179-84. 2012
    ..Unlike the maximum standardized uptake value (SUVmax), which represents the point of greatest metabolic activity within tumors, TLG has been suggested to reflect global metabolic activity in whole tumors...
  17. doi request reprint Morphometric image analysis of pancreatic disease by ThinPrep liquid-based cytology
    Tomoki Taira
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    Diagn Cytopathol 40:970-5. 2012
    ..05). Pancreatic cytological findings of TP preparations generally show small, round cluster shapes in pancreatic disease; however, nucleus size is a more important criteria for detecting malignancy by TP in pancreatic disease...
  18. doi request reprint Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer: a retrospective analysis
    Tsukasa Yoshida
    Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume City, Fukuoka 830 0011, Japan
    Med Oncol 30:349. 2013
    ....
  19. doi request reprint Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with carboplatin and paclitaxel
    Koichi Azuma
    Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    Lung Cancer 64:326-33. 2009
    ....
  20. doi request reprint Association of the expression of mutant epidermal growth factor receptor protein as determined with mutation-specific antibodies in non-small cell lung cancer with progression-free survival after gefitinib treatment
    Koichi Azuma
    Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    J Thorac Oncol 7:122-7. 2012
    ..Molecular markers for prediction of EGFR-TKI treatment efficacy in EGFR mutation-positive NSCLC have not been well defined...
  21. doi request reprint The difference in relationship between 18F-FDG uptake and clinicopathological factors on thyroid, esophageal, and lung cancers
    Hayato Kaida
    aDivision of Nuclear Medicine, PET Center, and Department of Radiology, Kurume University School of Medicine bDepartment of Diagnostic Pathology, Kurume University Hospital cBiostatistics Center dDivision of Respirology, Neurology, and Rheumatology, Department of Internal Medicine eDepartment of Surgery fDivision of Endocrinology, Department of Internal Medicine gDepartment of Otolaryngology and Facial Maxillary Surgery, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Nucl Med Commun 35:36-43. 2014
    ....
  22. ncbi request reprint Extracellular material in adenoid cystic carcinoma of the salivary glands: a comparative cytological study with other salivary myoepithelial tumors
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital and Kurume University School of Medicine, Kurume, Japan
    Diagn Cytopathol 31:14-8. 2004
    ..However, AdCC has the greatest variety of ECM. These findings are useful to understand the character of AdCC and differential diagnosis of the other salivary gland tumors with myoepithelial differentiation...
  23. ncbi request reprint Decreased expression of claudin-1 in rectal cancer: a factor for recurrence and poor prognosis
    Takefumi Yoshida
    Department of Surgery, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    Anticancer Res 31:2517-25. 2011
    ..To investigate the potential involvement of claudin-1 (CL-1) in the tumorigenesis of rectal cancer by analyzing the correlation between CL-1 expression, clinicopathological factors and prognosis...
  24. doi request reprint Morphometric analysis and p63 improve the identification of myoepithelial cells in breast lesion cytology
    Emiko Aikawa
    Department of Diagnostic Pathology, Kurume University Hospital, 67 Asahi Machi, Kurume, Japan
    Diagn Cytopathol 39:172-6. 2011
    ..189). Although the identification of normal myoepithelial cells is mainly performed by immunostaining for p63, morphometric analysis of the nucleus area also suggests the existence of p63-positive myoepithelial cells...
  25. doi request reprint Expression of HER2 and estrogen receptor alpha depends upon nuclear localization of Y-box binding protein-1 in human breast cancers
    Teruhiko Fujii
    Center for Innovative Cancer Therapy of the 21st Century Center of Excellence Program for Medical Science, Department of Surgery, Kurume University School of Medicine, Kurume, Japan
    Cancer Res 68:1504-12. 2008
    ..The nuclear localization of YB-1 could be an important therapeutic target against not only multidrug resistance but also tumor growth dependent on HER2 and ER alpha...
  26. ncbi request reprint N-myc downstream regulated gene 1 (NDRG1)/Cap43 enhances portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma
    Jun Akiba
    Department of Pathology, Kurume University School of Medicine, Fukuoka 830 0011, Japan
    Oncol Rep 20:1329-35. 2008
    ..No clear relationship between the expression and prognosis was observed. NDRG1/Cap43 expression that was found in advanced HCC was thought to accelerate tumor invasion and metastasis. NDRG1/Cap43 could act as a useful biomarker of HCC...
  27. doi request reprint Fixation effect of SurePath preservative fluids using epidermal growth factor receptor mutation-specific antibodies for immunocytochemistry
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan
    Cancer Cytopathol 122:145-52. 2014
    ..The aim of this study was to investigate the fixation effect of SurePath preservative fluids...
  28. doi request reprint Humoral Immune Responses to EGFR-Derived Peptides Predict Progression-Free and Overall Survival of Non-Small Cell Lung Cancer Patients Receiving Gefitinib
    Koichi Azuma
    Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    PLoS ONE 9:e86667. 2014
    ..Our results may provide new insight for better understanding of humoral responses to EGFR in NSCLC patients. ..
  29. doi request reprint Clinicopathological significance of hypoxia-inducible factor-1 alpha (HIF-1α) expression in gastric cancer
    Taro Isobe
    Department of Surgery, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, 830 0011, Japan
    Int J Clin Oncol 18:293-304. 2013
    ..In this study, we evaluated the significance of HIF-1α expression in relationship to clinicopathological factors, prognosis, vascular endothelial growth factor (VEGF) expression, and microvessel density (MVD)...
  30. pmc Prognostic value of EGFR mutation and ERCC1 in patients with non-small cell lung cancer undergoing platinum-based chemotherapy
    Fumie Yamashita
    Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    PLoS ONE 8:e71356. 2013
    ..The aim of this study was to assess the role of EGFR mutations and ERCC1 in predicting the efficacy of platinum-based chemotherapy and the outcome of patients with NSCLC...
  31. ncbi request reprint Expression of monocarboxylate transporter (MCT)-4 in colorectal cancer and its role: MCT4 contributes to the growth of colorectal cancer with vascular endothelial growth factor
    Yukito Gotanda
    Department of Surgery, School of Medicine, Kurume University, Fukuoka, Japan
    Anticancer Res 33:2941-7. 2013
    ..Similarly, vascular endothelial growth factor (VEGF) is known to be involved in the growth, infiltration, and metastasis of tumors. In this study, we clinically evaluated the relationship between MCT4 and VEGF in colorectal cancer...
  32. doi request reprint The relationship between 18F-FDG metabolic volumetric parameters and clinicopathological factors of breast cancer
    Hayato Kaida
    Department of Radiology, PET Center, Division of Nuclear Medicine, Kurume University School of Medicine, Fukuoka, Japan
    Nucl Med Commun 34:562-70. 2013
    ....
  33. ncbi request reprint Increased claudin-1 protein expression in hepatic metastatic lesions of colorectal cancer
    Tetsushi Kinugasa
    Department of Surgery, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, Japan
    Anticancer Res 32:2309-14. 2012
    ..The possible involvement of claudin-1 (CL-1), which is one of the major tight junctional proteins, was investigated in the tumorigenesis of hepatic metastasis in patients with colorectal cancer (CRC)...
  34. doi request reprint Relation between (99m)Tc-tetrofosmin thyroid scintigraphy and mitogen-activated protein kinase in papillary thyroid cancer patients
    Kenkichi Baba
    Division of Nuclear Medicine, PET Center, Department of Radiology, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Jpn J Radiol 29:533-9. 2011
    ..The aim of this study was to investigate the relation between (99m)Tc-tetrofosmin uptake and extracellular signal-regulated kinase mitogen-activated protein kinase (ERK MAPK) expression in papillary thyroid cancer patients...
  35. doi request reprint Accuracy of differential diagnosis for pancreatic cancer is improved in the combination of RCAS1 and CEA measurements and cytology in pancreatic juice
    Yoshiki Naito
    Department of Pathology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830 0011, Japan
    Med Mol Morphol 44:86-92. 2011
    ..We concluded that RCAS1 and CEA measurements together with cytology in pancreatic juice would be a useful combination method for making a differential diagnosis of PC from non-PC...
  36. doi request reprint N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase
    Jun Akiba
    Department of Pathology, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Cancer Lett 310:25-34. 2011
    ..NDRG1/Cap43 overexpression thus induced cell cycle arrest at the G0/G1 phase accompanied by increased p21 and decreased CDK4 expression in HCC cells. NDRG1/Cap43 might play a key role in the cell cycle control of G0/G1 in HCC cells...
  37. ncbi request reprint Cytopathological features of an epithelial-myoepithelial carcinoma with predominant clear myoepithelial cells in the parotid gland
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Kurume, Japan
    Diagn Cytopathol 30:280-3. 2004
    ..In addition to cytological findings, the cytological diagnosis of EMC with predominant clear myoepithelial cells requires a definite expression to SMA...
  38. ncbi request reprint Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis
    Yuichiro Maruyama
    Department of Surgery, Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Japan
    Cancer Res 66:6233-42. 2006
    ..0244), and overall survival rates for patients with pancreatic cancer (P = 0.0062). Thus, Cap43 could play a key role in the angiogenic on- or off-switch of tumor stroma in pancreatic ductal adenocarcinoma...
  39. doi request reprint Phase II study of personalized peptide vaccination for refractory bone and soft tissue sarcoma patients
    Ryuji Takahashi
    Department of Surgery, Kurume University School of Medicine, Kurume, Japan
    Cancer Sci 104:1285-94. 2013
    ..Taken together, PPV could be feasible for the vast majority of refractory sarcoma patients because of the safety and higher rates of immunological responses regardless of the presence of different sarcoma subtypes and various HLA-types...
  40. doi request reprint Decreased expression of insulin and increased expression of pancreatic transcription factor PDX-1 in islets in patients with liver cirrhosis: a comparative investigation using human autopsy specimens
    Masahiro Sakata
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, 830 0011, Japan
    J Gastroenterol 48:277-85. 2013
    ..Therefore, we investigated the histopathological differences in islets of Langerhans cells between LC and T2DM...
  41. pmc Intraductal neoplasm of the intrahepatic bile duct: clinicopathological study of 24 cases
    Yoshiki Naito
    Departments of Pathology, Kurume University School of Medicine, Kurume 830 0011, Japan
    World J Gastroenterol 18:3673-80. 2012
    ..To investigate the clinicopathological features of intraductal neoplasm of the intrahepatic bile duct (INihB)...
  42. doi request reprint Guide to diagnosing primary pancreatic lymphoma, B-cell type: immunocytochemistry improves the diagnostic accuracy of endoscopic ultrasonography-guided fine needle aspiration cytology
    Yoshiki Naito
    Department of Pathology, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, Japan
    Diagn Cytopathol 40:732-6. 2012
    ..Taking these findings together with the cytopathologic findings, this specimen was reconfirmed as PPL. Immunocytochemical examination for LCA and CD20 is useful in the identification of malignant pancreatic lymphoma, B-cell type...
  43. doi request reprint Histiocytic sarcoma of the parotid gland region
    Jun Akiba
    Department of Pathology, Kurume University School of Medicine, Kurume, Japan
    Pathol Int 61:373-6. 2011
    ..Monoclonal proliferation of B cells was not confirmed on polymerase chain reaction for IgH. The patient had recurrent lesions in the pelvis and stomach 5 months after parotidectomy and died of the disease 10 months after the operation...
  44. ncbi request reprint Expression of dihydropyrimidine dehydrogenase, orotate phosphoribosyl transferase and thymidylate synthase in patients with primary colorectal cancer, and associations with site of first metastasis
    Yoshito Akagi
    Department of Surgery, Kurume University School of Medicine, 67 Asahimachi, Kurume 830 0011, Japan
    Anticancer Res 32:2277-82. 2012
    ..This study compared the expression levels of these enzymes between primary colorectal cancer with and without distant metastases, and examined whether these expression patterns are associated with hematogenous metastasis...
  45. doi request reprint Follow-up evaluation of radiation-induced DNA damage in CSF disseminated high-grade glioma using phospho-histone H2AX antibody
    Hideyuki Abe
    Department of Diagnostic Pathology, Kurume University Hospital, Japan
    Diagn Cytopathol 40:435-9. 2012
    ..CSF cytology is an effective means of evaluating DNA damage in tumor cells after irradiation, and may be useful in assessing the therapeutic response...
  46. ncbi request reprint Cytomorphologic features of a polymorphous low grade adenocarcinoma of the palate. A report of 2 cases with immunocytochemistry
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, 67 Asahi Machi, Kurume 830 0011, Japan
    Acta Cytol 47:1127-30. 2003
    ..Here we report 2 cases of PLGA originating in the palate and describe the cytomorphologic and immunocytochemical features...
  47. doi request reprint Cytological features of myxomatous fibroadenoma of the breast
    Rin Yamaguchi
    Department of Pathology, Kurume University Medical Center, Kurume, Japan
    Diagn Cytopathol 40:316-20. 2012
    ..Combining cytological examination and understanding the clinical features of M-FA may allow us to choose cytological examination as a first-line diagnostic method for tumor-forming lesions...
  48. ncbi request reprint Comparison of preoperative fine-needle aspiration cytology diagnosis and histopathological diagnosis of salivary gland tumors
    Hiroyuki Mihashi
    Department of Pathology, Kurume University Hospital, 67 Asahi Machi, Kurume 830 0011, Japan
    Kurume Med J 53:23-7. 2006
    ..We consider it necessary to adequately re-aspirate the solid portion after cyst fluid aspiration, or to re-perform FNAC at a later date, and to improve the diagnostic accuracy by further experience with more patients...
  49. ncbi request reprint Image analysis of irregularity of cluster shape in cytological diagnosis of breast tumors: cluster analysis with 2D-fractal dimension
    Toshiro Yokoyama
    Department of Pathology, Kurume University Hospital, Japan
    Diagn Cytopathol 33:71-7. 2005
    ..For accurate diagnosis, the cell cluster shape is as important as the individual cellular atypia...
  50. ncbi request reprint Characterization of the epithelial components in pleomorphic adenoma of the salivary gland
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Kurume University School of Medicine, Asahimachi, Kurume, Japan
    Acta Cytol 46:1095-100. 2002
    ..To clarify the cytomorphologic characteristics of luminal epithelial cells (LEC) and neoplastic myoepithelial cells (NMC) in pleomorphic adenoma (PA)...
  51. ncbi request reprint Combined treatment with prednisolone and tacrolimus for myasthenia gravis with invasive thymoma
    Shiroh Miura
    Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Acta Neurol Belg 110:107-9. 2010
    ..We stress the usefulness of combined treatment with tacrolimus and prednisolone for invasive thymoma, especially for unresectable tumors...
  52. doi request reprint Relationship between clinicopathological factors and fluorine-18-fluorodeoxyglucose uptake in patients with papillary thyroid cancer
    Hayato Kaida
    Division of Nuclear Medicine, PET Center, Department of Radiology, Kurume University School of Medicine, Kurume City, Fukuoka, Japan
    Nucl Med Commun 32:690-8. 2011
    ..To examine the relationship between clinicopathological factors and fluorine-18-fluorodeoxyglucose (F-FDG) uptake in patients with papillary thyroid cancer (PTC)...
  53. doi request reprint Glucose transporter expression of an esophageal gastrointestinal tumor detected by F-18 FDG PET/CT
    Hayato Kaida
    Division of Nuclear Medicine, PET Center and Department of Radiology, Kurume University School of Medicine, Kurume City, Fukuoka, Japan
    Clin Nucl Med 35:505-9. 2010
    ..GLUT-3 had no expression on membranes or in cytoplasm. Esophageal GIST is rare and the relationship between GLUT expression and F-18 FDG accumulation in GIST is probably rare...
  54. doi request reprint A case of metastasizing pleomorphic adenoma in the maxillary bone appearing twenty years after initial resection of pleomorphic adenoma of the hard palate
    Jun Akiba
    Department of Pathology, Kurume University School of Medicine, Kurume, Japan
    Pathol Int 63:463-8. 2013
    ..However, no gene rearrangements of PLAG1 were found. We report here on a case of MPA in the maxillary bone, which appeared 20 years after resection of the primary tumor and review the relevant literature. ..
  55. doi request reprint Erlotinib resistance in lung cancer cells mediated by integrin β1/Src/Akt-driven bypass signaling
    Rina Kanda
    Authors Affiliations Department of Pharmaceutical Oncology and Laboratory of Molecular Cancer Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka Department of Diagnostic Pathology, Kurume University Hospital, Kurume Section of Functional Morphology, Faculty of Pharmaceutical Science, Nagasaki International University, Nagasaki Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu St Mary s Institute of Health Science, St Mary s Hospital, Kurume, Japan and Pangaea Biotech, Dexeus University Institute, Barcelona, Spain
    Cancer Res 73:6243-53. 2013
    ..Together, our findings identify the integrin β1/Src/Akt signaling pathway as a key mediator of acquired resistance to EGFR-targeted anticancer drugs...
  56. doi request reprint Immunological evaluation of personalized peptide vaccination in refractory small cell lung cancer
    Yasuhiro Terazaki
    Department of Surgery, Kurume University School of Medicine, Kurume, Japan
    Cancer Sci 103:638-44. 2012
    ..084; respectively). Based on the feasible immune responses in refractory SCLC patients who received at least one cycle (six times) of vaccinations, PPV could be recommended for a next stage of larger-scale, prospective clinical trials...
  57. doi request reprint CD14 expression and Kupffer cell dysfunction in non-alcoholic steatohepatitis: superparamagnetic iron oxide-magnetic resonance image and pathologic correlation
    Tatsuyuki Tonan
    Department of Radiology, Kurume University School of Medicine, Kurume, Japan
    J Gastroenterol Hepatol 27:789-96. 2012
    ..We investigated the relationship of KC function with superparamagnetic iron oxide-enhanced magnetic resonance imaging (SPIO-MRI), histopathological severity of NASH, and number of CD14-positive KCs in NASH...
  58. doi request reprint Usefulness of lavage cytology during endoscopic transpapillary catheterization into the gallbladder in the cytological diagnosis of gallbladder disease
    Yoshiki Naito
    Department of Pathology, Kurume University School of Medicine, Kurume, Japan
    Diagn Cytopathol 37:402-6. 2009
    ....
  59. pmc Potential usefulness of mucin immunohistochemical staining of preoperative pancreatic biopsy or juice cytology specimens in the determination of treatment strategies for intraductal papillary mucinous neoplasm
    Toru Hisaka
    Department of Surgery, Kurume University School of Medicine, Kurume, Fukuoka 830 0011, Japan
    Oncol Rep 30:2035-41. 2013
    ....
  60. doi request reprint Glucose transporter expression of intraductal papilloma of the breast detected by fluorodeoxyglucose positron emission tomography
    Yasumitsu Hirose
    Division of Nuclear Medicine, PET Center and Department of Radiology, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Jpn J Radiol 29:217-21. 2011
    ..This case suggests that other glucose transporters (e.g., GLUT-4), other pathological factors, and cytokines may have a close relation with (18)F-FDG accumulation in intraductal papilloma more than GLUT-1 or GLUT-3 expression...