Tatsuya Ide

Summary

Affiliation: Kurume University School of Medicine
Country: Japan

Publications

  1. pmc No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations
    Hiromi Sawai
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Med Genet 13:47. 2012
  2. pmc Significance of a reduction in HCV RNA levels at 4 and 12 weeks in patients infected with HCV genotype 1b for the prediction of the outcome of combination therapy with peginterferon and ribavirin
    Hidenori Toyoda
    Department of Gastroenterology, Ogaki Municipal Hospital, Ogaki, Japan
    BMC Infect Dis 12:324. 2012
  3. ncbi request reprint A pilot study of eicosapentaenoic acid therapy for ribavirin-related anemia in patients with chronic hepatitis C
    Tatsuya Ide
    Second Department of Internal Medicine, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 11:729-32. 2003
  4. doi request reprint A randomized study of extended treatment with peginterferon alpha-2b plus ribavirin based on time to HCV RNA negative-status in patients with genotype 1b chronic hepatitis C
    Tatsuya Ide
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka Ken, Japan
    Am J Gastroenterol 104:70-5. 2009
  5. doi request reprint Predictive factors associated with the progression to hepatic failure caused by lamivudine-resistant HBV
    Reiichiro Kuwahara
    Kurume University School of Medicine, Kurume, 830 0011, Japan
    Dig Dis Sci 53:2999-3006. 2008
  6. doi request reprint Phase I clinical study of a peptide vaccination for hepatitis C virus-infected patients with different human leukocyte antigen-class I-A alleles
    Shigeru Yutani
    Department of Immunology and Immunotherapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Cancer Sci 100:1935-42. 2009
  7. ncbi request reprint Clinical course of patients with chronic hepatitis B with viral breakthrough during long-term lamivudine treatment
    Tatsuya Ide
    Second Department of Internal Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, 830 0011, Japan
    J Gastroenterol 40:625-30. 2005
  8. ncbi request reprint Genetic heterogeneity of the precore and the core promoter region of genotype C hepatitis B virus during lamivudine therapy
    Reiichiro Kuwahara
    The Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    J Med Virol 72:26-34. 2004
  9. ncbi request reprint Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Am J Gastroenterol 102:570-6. 2007
  10. ncbi request reprint Subclones of drug-resistant hepatitis B virus mutants and the outcome of breakthrough hepatitis in patients treated with lamivudine
    Ryukichi Kumashiro
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Intervirology 46:350-4. 2003

Collaborators

Detail Information

Publications44

  1. pmc No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations
    Hiromi Sawai
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    BMC Med Genet 13:47. 2012
    ....
  2. pmc Significance of a reduction in HCV RNA levels at 4 and 12 weeks in patients infected with HCV genotype 1b for the prediction of the outcome of combination therapy with peginterferon and ribavirin
    Hidenori Toyoda
    Department of Gastroenterology, Ogaki Municipal Hospital, Ogaki, Japan
    BMC Infect Dis 12:324. 2012
    ..We conducted a multicenter study to validate this importance along with baseline predictive factors in this patient subpopulation...
  3. ncbi request reprint A pilot study of eicosapentaenoic acid therapy for ribavirin-related anemia in patients with chronic hepatitis C
    Tatsuya Ide
    Second Department of Internal Medicine, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 11:729-32. 2003
    ..5 g/dl). None of the patients developed an adverse reaction. These findings suggest that EPA has a beneficial effect in patients with ribavirin-related anemia. Further study is required to confirm our results...
  4. doi request reprint A randomized study of extended treatment with peginterferon alpha-2b plus ribavirin based on time to HCV RNA negative-status in patients with genotype 1b chronic hepatitis C
    Tatsuya Ide
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka Ken, Japan
    Am J Gastroenterol 104:70-5. 2009
    ..Although many studies extended the duration of therapy from 48 weeks to 72 weeks, the optimal duration has not yet been determined...
  5. doi request reprint Predictive factors associated with the progression to hepatic failure caused by lamivudine-resistant HBV
    Reiichiro Kuwahara
    Kurume University School of Medicine, Kurume, 830 0011, Japan
    Dig Dis Sci 53:2999-3006. 2008
    ....
  6. doi request reprint Phase I clinical study of a peptide vaccination for hepatitis C virus-infected patients with different human leukocyte antigen-class I-A alleles
    Shigeru Yutani
    Department of Immunology and Immunotherapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Cancer Sci 100:1935-42. 2009
    ..Because of its tolerability and higher rate of immune boosting, this protocol is recommended for a phase II study to investigate its clinical efficacy...
  7. ncbi request reprint Clinical course of patients with chronic hepatitis B with viral breakthrough during long-term lamivudine treatment
    Tatsuya Ide
    Second Department of Internal Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, 830 0011, Japan
    J Gastroenterol 40:625-30. 2005
    ..We evaluated the clinical course of patients with chronic hepatitis B who showed viral breakthrough during long-term lamivudine therapy...
  8. ncbi request reprint Genetic heterogeneity of the precore and the core promoter region of genotype C hepatitis B virus during lamivudine therapy
    Reiichiro Kuwahara
    The Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    J Med Virol 72:26-34. 2004
    ..The reversion in the precore region may be caused by the difference of drug-susceptibility to lamivudine. The antiviral effect of lamivudine may be more effective in the precore mutant HBV than in the precore wild type HBV...
  9. ncbi request reprint Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Am J Gastroenterol 102:570-6. 2007
    ..The aim of this study is to examine the effects of clearance of HCV on insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate (IRS)1/2, central molecules for insulin signaling...
  10. ncbi request reprint Subclones of drug-resistant hepatitis B virus mutants and the outcome of breakthrough hepatitis in patients treated with lamivudine
    Ryukichi Kumashiro
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Intervirology 46:350-4. 2003
    ..Further studies are needed for making out the effects of lamivudine-resistant mutants on clinical outcomes, taking into considerations genotypes of HBV...
  11. ncbi request reprint Adefovir dipivoxil as a treatment for hepatic failure caused by lamivudine-resistant HBV strains
    Reiichiro Kuwahara
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Dig Dis Sci 49:300-3. 2004
  12. ncbi request reprint The importance of a prior psychiatric examination in pegylated interferon and ribavirin combination treatment for chronic hepatitis C
    Koichiro Kuhara
    Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan
    Kurume Med J 59:39-44. 2012
    ..Conclusions: A psychiatric examination before pegylated interferon and ribavirin treatment was found to positively contribute to the successful completion of the treatment. ..
  13. doi request reprint Risk factors for hepatocellular carcinoma in Japanese patients with autoimmune hepatitis type 1
    Teruko Hino-Arinaga
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, 830 0011, Japan
    J Gastroenterol 47:569-76. 2012
    ..The aim of this study was to identify the incidence of and risk factors for HCC with AIH in a large-scale population with a long-term follow-up in Japan...
  14. ncbi request reprint HBV and HCV infection in Japanese dental care workers
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 21:791-9. 2008
    ..HBV vaccination should be made compulsory for all dental care workers who handle sharp instruments...
  15. ncbi request reprint [A periappendiceal abscess during combination interferon and ribavirin treatment for chronic hepatitis C]
    Teruko Hino
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine
    Nihon Shokakibyo Gakkai Zasshi 104:1632-8. 2007
    ..After colonoscopy study, fever decreased. We have to suspect abscess formation too as appearing a high fever during interferon and ribavirin combination treatment...
  16. ncbi request reprint A real-time quantitative polymerase chain reaction method for hepatitis B virus in patients with chronic hepatitis B treated with lamivudine
    Tatsuya Ide
    Second Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan
    Am J Gastroenterol 98:2048-51. 2003
    ..7 log copies/ml (50 copies/ml) to clarify its clinical significance, particularly the association between HBV DNA levels and the emergence of tyrosine-methionine-aspartate-aspartate (YMDD) mutants...
  17. ncbi request reprint Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area: a pilot study
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 16:109-14. 2005
    ..41 to 37.42). In conclusion, HCV infection potentially has a significant role in the development of type 2 diabetes mellitus at the population level. Further large-scale studies are needed to confirm these preliminary findings...
  18. ncbi request reprint Antibody to hepatitis B core antigen is associated with the development of hepatocellular carcinoma in hepatitis C virus-infected persons: a 12-year prospective study
    Kazuo Tanaka
    Second Department of Internal Medicine, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 17:827-32. 2006
    ..Our findings provide clear evidence in a prospective study that presence of anti-HBc, that is, past hepatitis B virus (HBV) infection, is a risk factor for the development of HCC in HCV-infected people...
  19. ncbi request reprint Phase I clinical study of a personalized peptide vaccination for patients infected with hepatitis C virus (HCV) 1b who failed to respond to interferon-based therapy
    Shigeru Yutani
    Department of Immunology, Kurume University School of Medicine, Japan
    Vaccine 25:7429-35. 2007
    ..Decrease of serum alanine aminotransferase and HCV-RNA levels after the 14th vaccination was also observed in five and three patients, respectively...
  20. doi request reprint A mutational shift from domain III to II in the internal ribosome entry site of hepatitis C virus after interferon-ribavirin therapy
    Kei Ogata
    Division of Infectious Diseases, Department of Infectious Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka, Japan
    Arch Virol 153:1575-9. 2008
    ..However, these mutations were exclusively observed in domain II (dII) in non-SVR at 2 weeks after the start of therapy...
  21. ncbi request reprint Thrombocytopenia, an important interfering factor of antiviral therapy and hepatocellular carcinoma treatment for chronic liver diseases
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Asahi machi, Kurume, Japan
    Kurume Med J 56:9-15. 2009
    ..In chronic liver disease patients with moderate and severe thrombocytopenia, about 85% of patients treated with peginterferon, and 60% of patients receiving HCC treatments suffered from thrombocytopenia-related limitations, respectively...
  22. ncbi request reprint Impaired filterability of erythrocytes from patients with chronic hepatitis C and effects of eicosapentaenoic acid on the filterability
    Ritsuko Seki
    Second Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, 830 0011, Japan
    J Physiol Sci 57:43-9. 2007
    ....
  23. ncbi request reprint Serum levels of IgG to the peptide of HCV1b core at positions 35-44 correlated with persistent infection, while levels of IgG to the peptide of NS5A at positions 2132-2140 correlated with better prognosis in HCV-infected patients
    Yukari Takao
    Department of Immunology, Kurume University School of Medicine, Kurume, Fukuoka 830 0011, Japan
    Med Microbiol Immunol 196:157-64. 2007
    ..These results suggest that sequential measurement of the two Abs together may provide new information for the prediction of prognosis...
  24. ncbi request reprint Lamivudine treatment-related morphological changes of esophageal varices in patients with liver cirrhosis
    Hiroyuki Koga
    Second Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan
    Hepatol Res 37:503-9. 2007
    ..However, in the three patients with worsening, the HA level significantly increased. Conclusion: Lamivudine treatment for patients with cirrhosis improves not only liver function but also esophageal varices...
  25. ncbi request reprint Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Int J Mol Med 22:105-12. 2008
    ..Thus, a BCAA-enriched supplement may be a useful therapeutic agent for decreasing insulin resistance in male patients with chronic viral liver disease...
  26. pmc Effect of branched-chain amino acid-enriched nutritional supplementation on interferon therapy in Japanese patients with chronic hepatitis C virus infection: a retrospective study
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Virol J 9:282. 2012
    ....
  27. ncbi request reprint Predictive factors for remission and death in 73 patients with autoimmune hepatitis in Japan
    Teruko Hino
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka 830 0011, Japan
    Int J Mol Med 11:749-55. 2003
    ..03). The results of this study show an importance of achieving a good PSL response at onset, and that initial TB, the AST/ALT ratio, and IgG levels are useful for therapeutic strategy...
  28. pmc Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
    Takumi Kawaguchi
    Second Department of Medicine, Kurume University School of Medicine 67 Asahi machi, Kurume 830 0011, Japan
    Am J Pathol 165:1499-508. 2004
    ..In conclusion, HCV infection changes a subset of hepatic molecules regulating glucose metabolism. A possible mechanism is that HCV core-induced SOCS3 promotes proteosomal degradation of IRS1 and IRS2 through ubiquitination...
  29. ncbi request reprint Adipocytokine involvement in hepatocellular carcinoma after sustained response to interferon for chronic hepatitis C
    Nobuyoshi Fukushima
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume
    Hepatol Res 40:911-22. 2010
    ..Conclusion:  Hepatic fibrosis may be tightly related to the emergence of HCC after SVR. Insulin resistance and adipocytokine disorders may be implicated in hepatocarcinogenesis after SVR, in part by promoting hepatic fibrosis...
  30. ncbi request reprint Successful treatment with corticosteroid and lamivudine for autoimmune hepatitis in a patient with asymptomatic HBV infection
    Reiichiro Kuwahara
    The Second Department of Medicine, Kurume University School of Medicine and the Center of the 21st Century Center of Excellence Program for Medical Science, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    Dig Dis Sci 52:908-13. 2007
  31. ncbi request reprint Knowledge of Vibrio vulnificus infection among Japanese patients with liver diseases: a prospective multicenter study
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Med Sci Monit 15:PH115-120. 2009
    ..The present study was conducted to assess the level of knowledge of patients with liver disease regarding V. vulnificus infection...
  32. ncbi request reprint A new epitope peptide derived from hepatitis C virus 1b possessing the capacity to induce cytotoxic T-lymphocytes in HCV1b-infected patients with HLA-A11, -A31, and -A33
    Satoko Matsueda
    Department of Immunology, Kurume University School of Medicine, Kurume, Fukuoka, 830 0011, Japan
    Cancer Immunol Immunother 56:1359-66. 2007
    ..Among various genotypes of HCV, HCV1b is resistant to standard interferon therapy, and thus the development of new treatment modality is needed...
  33. ncbi request reprint Peginterferon-alpha-2b plus ribavirin therapy in patients with chronic hepatitis C as assessed by a multi-institutional questionnaire in Japan
    Tatsuya Ide
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Hepatol Res 40:557-65. 2010
    ..Conclusion: The questionnaire survey provided new information that has never been reported. It is believed that understanding this information is important for future treatment...
  34. ncbi request reprint Incidence of Sjögren's syndrome in Japanese patients with hepatitis C virus infection
    Yumiko Nagao
    Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    J Gastroenterol Hepatol 18:258-66. 2003
    ..The purpose of the present study was to evaluate Sjögren's syndrome (SS) and lichen planus (LP) involvement, which are various extrahepatic manifestations in patients with liver diseases related to hepatitis B virus (HBV) or HCV...
  35. ncbi request reprint Predicting relapse after cessation of Lamivudine monotherapy for chronic hepatitis B virus infection
    Kiyoaki Ito
    Department of Gastroenterology, Chukyo Hospital, Nagoya, Japan
    Clin Infect Dis 38:490-5. 2004
    ..27-0.9). More-prolonged lamivudine therapy is required after seroconversion, and persistent duration of an HBV DNA level of <0.7 log IU/mL for >6 months can more accurately aid in the decision of when to stop lamivudine therapy...
  36. ncbi request reprint Prognostic indicators of breakthrough hepatitis during lamivudine monotherapy for chronic hepatitis B virus infection
    Yasuhito Tanaka
    Department of Clinical Molecular Informative Medicine, Nagoya City University Medical School Graduate School of Sciences, Kawasumi 1, Mizuho, 467 8601 Nagoya, Japan
    J Gastroenterol 39:769-75. 2004
    ..There have been many reports of lamivudine-resistant mutations within the C domain of the viral reverse transcriptase; however, the appearance of these mutants is not necessarily correlated with BTH during lamivudine therapy...
  37. ncbi request reprint [Routes of transmission of hepatitis C virus in hyperendemic areas, and molecular epidemiologic study of hepatitis C virus infection]
    Kazuo Tanaka
    Second Department of Medicine, Kurume University School of Medicine
    Nihon Rinsho 62:258-63. 2004
  38. ncbi request reprint [HCV or HBV infection self-disclosure to dentists]
    Yumiko Nagao
    Department of Digestive Disease Information and Research, Kurume University School of Medicine
    Kansenshogaku Zasshi 82:213-9. 2008
    ..The government should take appropriate measures to encourage and support dentists who use precautions to prevent nosocomial infection...
  39. ncbi request reprint Risk factors for development of hepatocellular carcinoma in patients with chronic hepatitis C after sustained response to interferon
    Masafumi Ikeda
    Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    J Gastroenterol 40:148-56. 2005
    ..Our aim was to elucidate the incidence and clinical features of, and risk factors for, HCC in sustained responders to IFN, taken for the treatment of chronic hepatitis C...
  40. ncbi request reprint Clinical features of hepatocellular carcinoma that occur after sustained virological response to interferon for chronic hepatitis C
    Masafumi Ikeda
    Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    J Gastroenterol Hepatol 21:122-8. 2006
    ..This study investigated the clinical features of hepatocellular carcinoma in patients with sustained virological response to interferon for hepatitis C viral (HCV) infection...
  41. ncbi request reprint New epitope peptides derived from hepatitis C virus (HCV) 2a which have the capacity to induce cytotoxic T lymphocytes in HLA-A2+ HCV-infected patients
    Yi Wang
    Cancer Vaccine Development Division, Kurume University Research Center for Innovative Cancer Therapy, Fukuoka, Japan
    Microbiol Immunol 50:857-65. 2006
    ..These results indicate that the HCV2a 432-441, HCV2a 716-724, and HCV2a 2251-2260 peptides might be applicable for peptide-based immunotherapy of HLA-A2+ HCV2a-infected patients...
  42. ncbi request reprint A decrease in AFP level related to administration of interferon in patients with chronic hepatitis C and a high level of AFP
    Shiro Murashima
    Department of Internal Medicine, Kurume Medical Center, Kurume, Fukuoka, Japan
    Dig Dis Sci 51:808-12. 2006
    ..Since AFP is a significant predictor for HCC, therapeutic strategies for hepatitis C, e.g., long-term low-dose IFN treatment, may reduce hepatocarcinogenesis...
  43. ncbi request reprint Severe alcoholic hepatitis successfully treated by leukocytapheresis: a case report
    Yoshiyasu Tsuji
    Department of Radiology, Kurume University, School of Medicine, Kurume, Fukuoka, Japan
    Alcohol Clin Exp Res 27:26S-31S. 2003
    ..The prognosis of severe alcoholic hepatitis is poor, and there is no established method for a cure...
  44. ncbi request reprint [A case of drug induced liver injury related pioglitazone]
    Akiko Hisamochi
    Second Department of Medicine, Kurume University School of Medicine
    Nihon Shokakibyo Gakkai Zasshi 100:333-6. 2003