Kazuhiko Kurosawa

Summary

Country: Japan

Publications

  1. ncbi Reversal of multidrug resistance by novel nitrophenyl pyrones, SNF4435C and D
    K Kurosawa
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Ishibashi Machi, Shimotsuga gun, Tochigi 329 0512
    Jpn J Cancer Res 92:1235-41. 2001
  2. ncbi SNF4435C and D, novel immunosuppressants produced by a strain of Streptomyces spectabilis. III. Immunosuppressive efficacy
    Kazuhiko Kurosawa
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Tochigi, Japan
    J Antibiot (Tokyo) 55:71-7. 2002
  3. ncbi Ushikulides A and B, immunosuppressants produced by a strain of Streptomyces sp
    Kosaku Takahashi
    Graduate School of Agriculture, Hokkaido University, Sapporo, 060 8589, Japan
    J Antibiot (Tokyo) 58:420-4. 2005

Collaborators

Detail Information

Publications3

  1. ncbi Reversal of multidrug resistance by novel nitrophenyl pyrones, SNF4435C and D
    K Kurosawa
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Ishibashi Machi, Shimotsuga gun, Tochigi 329 0512
    Jpn J Cancer Res 92:1235-41. 2001
    ..2 mg/kg VCR for every 5 days, a treated/control (T/C) value of 143% was obtained. These results suggest that the compounds are useful candidates or tools for MDR modification in cancer chemotherapy...
  2. ncbi SNF4435C and D, novel immunosuppressants produced by a strain of Streptomyces spectabilis. III. Immunosuppressive efficacy
    Kazuhiko Kurosawa
    Research Institute of Life Science, Snow Brand Milk Products Co, Ltd, Tochigi, Japan
    J Antibiot (Tokyo) 55:71-7. 2002
    ..These results were distinct from the behaviors observed with FK-506. SNF4435C, the major component, suppressed mouse delayed type hypersensitivity (DTH) and prolonged rat skin allograft survival...
  3. ncbi Ushikulides A and B, immunosuppressants produced by a strain of Streptomyces sp
    Kosaku Takahashi
    Graduate School of Agriculture, Hokkaido University, Sapporo, 060 8589, Japan
    J Antibiot (Tokyo) 58:420-4. 2005
    ..The structures of both compounds were elucidated to be novel 22-membered macrolides. Both compounds showed immunosuppressive activity for murine splenocyte proliferation in vitro...