Research Topics
Genomes and Genes | Yoshihiro WadaSummaryAffiliation: Kumamoto University Country: Japan Publications
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Publications
Isolated renal tuberculosis following intravesical Bacillus Calmette-Guérin therapy for bladder cancerYoshihiro Wada
Department of Urology, Kumamoto University School of Medicine, Kumamoto, Japan
Urol Int 72:257-60. 2004....- Docetaxel, low-dose estramustine, and doxifluridine in hormone-refractory metastatic prostate cancerYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
Cancer Chemother Pharmacol 61:53-61. 2008..Therefore, we examined the efficacy of adding 5'-dFUrd on the chemotherapy regimen, which consist docetaxel and estramustine... 
Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulinYoji Murakami
Department of Urology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Kumamoto 860 8556, Japan
Biol Chem 393:1193-200. 2012..sobria infection sites. However, as shown by fluorescence correlation spectroscopy, slow ASP inhibition by α2-MG in plasma may indicate insufficient ASP control in vivo...- Prostate expression of endothelins and their receptors in rat growthYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860 8556, Japan
Reprod Fertil Dev 20:750-9. 2008..The highest expression of ETA and the ligands at 3 weeks, followed by dramatic growth at 3 months in the DLP, suggests a role of ETA-mediated signal transduction in prostate growth of rats and possibly of humans... - Effects of diabetes on nitric oxide-mediated relaxations in male rat corpus cavernosum smooth muscleTomohiro Kuwahara
Department of Urology, Kumamoto University School of Medicine, Honjo, Kumamoto, Japan
Urol Int 71:399-407. 2003..CONCLUSION: The present data suggest that diabetes enhances nitric oxide synthase activity and nitric oxide-mediated relaxations in the male rat corpus cavernosum by the reduced testosterone level in the diabetic animals... - Lower urinary tract dysfunction in type 1 familial amyloidotic polyneuropathy in Kumamoto, JapanYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
Int J Urol 13:1475-8. 2006..To evaluate lower urinary tract dysfunction of type 1 familial amyloidotic polyneuropathy (FAP) patients in Kumamoto, Japan... 
Severe bleeding tendency caused by a rare complication of excessive fibrinolysis with disseminated intravascular coagulation in a 51-year-old Japanese man with prostate cancer: a case reportYoshihiro Wada
Department of Molecular Pathology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
J Med Case Rep 6:378. 2012..abstract:..- Production of C5a by ASP, a serine protease released from Aeromonas sobriaHidetoshi Nitta
Department of Molecular Pathology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
J Immunol 181:3602-8. 2008..Through C5a generation, ASP could be associated with the induction of pus and edema caused by infection with this bacterium... - The tail nick augments Aeromonas sobria serine protease (ASP) activity in plasma through retarding inhibition by α(2)-macroglobulinYoji Murakami
Department of Urology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Kumamoto 860 8556, Japan
FEBS Lett 586:3613-7. 2012..Retarded inhibition by α(2)-macroglobulin allows nASP to keep proteolytic activity for longer in the host and exacerbate disorders at Aeromonas sobria infection sites. nASP may be an evolutional form to augment ASP virulence... - Neurologic toxicity associated with interferon alpha therapy for renal cell carcinomaYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
Int J Urol 13:811-3. 2006..Complete remission of RCC has continued, and results of neurological study have remained normal for 5 years after discontinuation of IFN alpha therapy... - Regional differences in the functional and biochemical properties of endothelin receptor subtypes in the rabbit prostatic urethraYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
BJU Int 100:430-7. 2007..To examine the regional differences in the functional (pharmacological) and biochemical properties of endothelin (ET) receptors in the rabbit prostatic urethra... - Mass screening for prostate cancer in patients with end-stage renal disease: a comparative studyYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
BJU Int 98:794-7. 2006.... - Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancersJuro Nakanishi
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Honjo, Kumamoto, Japan
Cancer Immunol Immunother 56:1173-82. 2007.... - Current status of pharmacotherapy against metastatic renal cell carcinoma in JapanYoshihiro Wada
Department of Urology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Int J Urol 19:284-95. 2012..In this article, we reviewed the issues related to the current status of pharmacotherapy available for metastatic renal cell carcinoma... - Excessive fibrinolysis in AL-amyloidosis is induced by urokinae-type plasminogen activator from bone marrow plasma cellsMitsuhiro Uchiba
Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, Japan
Amyloid 16:89-93. 2009..The present data suggested that uPA expressed in plasma cells may have contributed to the pathogenesis of excessive fibrinolysis... - Modified technique for improving tubeless cutaneous ureterostomy by Ariyoshi methodYoshihiro Wada
Department of Urology, Graduate School of Medical Sciences, Kumamoto Unviersity, Kumamoto, Japan
Int J Urol 15:144-50; discussion 150. 2008..The remaining capillaries in the fascia could supply blood to the ureters, which is one of the most important factors for ureter patency... - Effects of castration on nitric oxide-mediated relaxations in male rat corpus cavernosum smooth muscleYoshihiro Wada
Department of Urology, Kumamoto University School of Medicine, Kumamoto, Japan
Urol Int 70:62-9. 2003..The effects of castration on nitric oxide- mediated relaxations and nitric oxide synthase activity in male rat corpus cavernosum smooth muscles... - Impaired plasma clottability induction through fibrinogen degradation by ASP, a serine protease released from Aeromonas sobriaTakahisa Imamura
Department of Molecular Pathology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
FEMS Microbiol Lett 284:35-42. 2008..sobria. Impaired plasma clottability induction through fibrinogen degradation is a new virulence activity of ASP and may contribute to hemorrhagic tendencies in sepsis caused by infection with this bacterium... - Gene expression analyses on embryonic external genitalia: identification of regulatory genes possibly involved in masculinization processesHisayo Nishida
Center for Animal Resources and Development CARD, Graduate School of Medical and Pharmaceutical Sciences, and Global COE Cell Fate Regulation Research and Education Unit, Kumamoto University, Kumamoto, Japan
Congenit Anom (Kyoto) 48:63-7. 2008..From our studies we have identified candidate genes, Cyp1b1, Fkbp51 and MafB as potential androgen targets during mouse GT masculinization...