Yoshihiro Wada

Summary

Affiliation: Kumamoto University
Country: Japan

Publications

  1. ncbi request reprint Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers
    Juro Nakanishi
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Honjo, Kumamoto, Japan
    Cancer Immunol Immunother 56:1173-82. 2007
  2. ncbi request reprint Isolated renal tuberculosis following intravesical Bacillus Calmette-Guérin therapy for bladder cancer
    Yoshihiro Wada
    Department of Urology, Kumamoto University School of Medicine, Kumamoto, Japan
    Urol Int 72:257-60. 2004
  3. ncbi request reprint Docetaxel, low-dose estramustine, and doxifluridine in hormone-refractory metastatic prostate cancer
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
    Cancer Chemother Pharmacol 61:53-61. 2008
  4. doi request reprint Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin
    Yoji Murakami
    Department of Urology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Kumamoto 860 8556, Japan
    Biol Chem 393:1193-200. 2012
  5. ncbi request reprint Effects of diabetes on nitric oxide-mediated relaxations in male rat corpus cavernosum smooth muscle
    Tomohiro Kuwahara
    Department of Urology, Kumamoto University School of Medicine, Honjo, Kumamoto, Japan
    Urol Int 71:399-407. 2003
  6. ncbi request reprint Prostate expression of endothelins and their receptors in rat growth
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860 8556, Japan
    Reprod Fertil Dev 20:750-9. 2008
  7. ncbi request reprint Lower urinary tract dysfunction in type 1 familial amyloidotic polyneuropathy in Kumamoto, Japan
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Int J Urol 13:1475-8. 2006
  8. doi request reprint Enhancement of human cancer cell motility and invasiveness by anaphylatoxin C5a via aberrantly expressed C5a receptor (CD88)
    Hidetoshi Nitta
    Department of Molecular Pathology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Clin Cancer Res 19:2004-13. 2013
  9. pmc Severe bleeding tendency caused by a rare complication of excessive fibrinolysis with disseminated intravascular coagulation in a 51-year-old Japanese man with prostate cancer: a case report
    Yoshihiro Wada
    Department of Molecular Pathology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
    J Med Case Rep 6:378. 2012
  10. ncbi request reprint Production of C5a by ASP, a serine protease released from Aeromonas sobria
    Hidetoshi Nitta
    Department of Molecular Pathology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    J Immunol 181:3602-8. 2008

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers
    Juro Nakanishi
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Honjo, Kumamoto, Japan
    Cancer Immunol Immunother 56:1173-82. 2007
    ....
  2. ncbi request reprint Isolated renal tuberculosis following intravesical Bacillus Calmette-Guérin therapy for bladder cancer
    Yoshihiro Wada
    Department of Urology, Kumamoto University School of Medicine, Kumamoto, Japan
    Urol Int 72:257-60. 2004
    ....
  3. ncbi request reprint Docetaxel, low-dose estramustine, and doxifluridine in hormone-refractory metastatic prostate cancer
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
    Cancer Chemother Pharmacol 61:53-61. 2008
    ..Therefore, we examined the efficacy of adding 5'-dFUrd on the chemotherapy regimen, which consist docetaxel and estramustine...
  4. doi request reprint Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin
    Yoji Murakami
    Department of Urology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Kumamoto 860 8556, Japan
    Biol Chem 393:1193-200. 2012
    ..sobria infection sites. However, as shown by fluorescence correlation spectroscopy, slow ASP inhibition by α2-MG in plasma may indicate insufficient ASP control in vivo...
  5. ncbi request reprint Effects of diabetes on nitric oxide-mediated relaxations in male rat corpus cavernosum smooth muscle
    Tomohiro Kuwahara
    Department of Urology, Kumamoto University School of Medicine, Honjo, Kumamoto, Japan
    Urol Int 71:399-407. 2003
    ..We evaluated the effects of diabetes on nitric oxide-mediated relaxations and nitric oxide synthase activity in male rat corpus cavernosum smooth muscles...
  6. ncbi request reprint Prostate expression of endothelins and their receptors in rat growth
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860 8556, Japan
    Reprod Fertil Dev 20:750-9. 2008
    ..The highest expression of ETA and the ligands at 3 weeks, followed by dramatic growth at 3 months in the DLP, suggests a role of ETA-mediated signal transduction in prostate growth of rats and possibly of humans...
  7. ncbi request reprint Lower urinary tract dysfunction in type 1 familial amyloidotic polyneuropathy in Kumamoto, Japan
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Int J Urol 13:1475-8. 2006
    ..To evaluate lower urinary tract dysfunction of type 1 familial amyloidotic polyneuropathy (FAP) patients in Kumamoto, Japan...
  8. doi request reprint Enhancement of human cancer cell motility and invasiveness by anaphylatoxin C5a via aberrantly expressed C5a receptor (CD88)
    Hidetoshi Nitta
    Department of Molecular Pathology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Clin Cancer Res 19:2004-13. 2013
    ..There is emerging evidence that C5a is generated in the cancer microenvironment. We therefore sought C5aR expression and a direct influence of the C5a-C5aR axis on cancer cells...
  9. pmc Severe bleeding tendency caused by a rare complication of excessive fibrinolysis with disseminated intravascular coagulation in a 51-year-old Japanese man with prostate cancer: a case report
    Yoshihiro Wada
    Department of Molecular Pathology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, 860 8556, Japan
    J Med Case Rep 6:378. 2012
    ..abstract:..
  10. ncbi request reprint Production of C5a by ASP, a serine protease released from Aeromonas sobria
    Hidetoshi Nitta
    Department of Molecular Pathology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    J Immunol 181:3602-8. 2008
    ..Through C5a generation, ASP could be associated with the induction of pus and edema caused by infection with this bacterium...
  11. doi request reprint The tail nick augments Aeromonas sobria serine protease (ASP) activity in plasma through retarding inhibition by α2-macroglobulin
    Yoji Murakami
    Department of Urology, Faculty of Life Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Kumamoto 860 8556, Japan
    FEBS Lett 586:3613-7. 2012
    ..Retarded inhibition by α(2)-macroglobulin allows nASP to keep proteolytic activity for longer in the host and exacerbate disorders at Aeromonas sobria infection sites. nASP may be an evolutional form to augment ASP virulence...
  12. ncbi request reprint Regional differences in the functional and biochemical properties of endothelin receptor subtypes in the rabbit prostatic urethra
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    BJU Int 100:430-7. 2007
    ..To examine the regional differences in the functional (pharmacological) and biochemical properties of endothelin (ET) receptors in the rabbit prostatic urethra...
  13. ncbi request reprint Neurologic toxicity associated with interferon alpha therapy for renal cell carcinoma
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Int J Urol 13:811-3. 2006
    ..Complete remission of RCC has continued, and results of neurological study have remained normal for 5 years after discontinuation of IFN alpha therapy...
  14. ncbi request reprint Mass screening for prostate cancer in patients with end-stage renal disease: a comparative study
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    BJU Int 98:794-7. 2006
    ....
  15. doi request reprint Current status of pharmacotherapy against metastatic renal cell carcinoma in Japan
    Yoshihiro Wada
    Department of Urology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Int J Urol 19:284-95. 2012
    ..In this article, we reviewed the issues related to the current status of pharmacotherapy available for metastatic renal cell carcinoma...
  16. doi request reprint Excessive fibrinolysis in AL-amyloidosis is induced by urokinae-type plasminogen activator from bone marrow plasma cells
    Mitsuhiro Uchiba
    Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, Japan
    Amyloid 16:89-93. 2009
    ..The present data suggested that uPA expressed in plasma cells may have contributed to the pathogenesis of excessive fibrinolysis...
  17. ncbi request reprint Effects of castration on nitric oxide-mediated relaxations in male rat corpus cavernosum smooth muscle
    Yoshihiro Wada
    Department of Urology, Kumamoto University School of Medicine, Kumamoto, Japan
    Urol Int 70:62-9. 2003
    ..The effects of castration on nitric oxide- mediated relaxations and nitric oxide synthase activity in male rat corpus cavernosum smooth muscles...
  18. doi request reprint Modified technique for improving tubeless cutaneous ureterostomy by Ariyoshi method
    Yoshihiro Wada
    Department of Urology, Graduate School of Medical Sciences, Kumamoto Unviersity, Kumamoto, Japan
    Int J Urol 15:144-50; discussion 150. 2008
    ..The remaining capillaries in the fascia could supply blood to the ureters, which is one of the most important factors for ureter patency...
  19. pmc Impaired plasma clottability induction through fibrinogen degradation by ASP, a serine protease released from Aeromonas sobria
    Takahisa Imamura
    Department of Molecular Pathology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
    FEMS Microbiol Lett 284:35-42. 2008
    ..sobria. Impaired plasma clottability induction through fibrinogen degradation is a new virulence activity of ASP and may contribute to hemorrhagic tendencies in sepsis caused by infection with this bacterium...
  20. doi request reprint Gene expression analyses on embryonic external genitalia: identification of regulatory genes possibly involved in masculinization processes
    Hisayo Nishida
    Center for Animal Resources and Development CARD, Graduate School of Medical and Pharmaceutical Sciences, and Global COE Cell Fate Regulation Research and Education Unit, Kumamoto University, Kumamoto, Japan
    Congenit Anom (Kyoto) 48:63-7. 2008
    ..From our studies we have identified candidate genes, Cyp1b1, Fkbp51 and MafB as potential androgen targets during mouse GT masculinization...