Takashi Uruno

Summary

Affiliation: Kuma Hospital
Country: Japan

Publications

  1. ncbi Favorable surgical results in 433 elderly patients with papillary thyroid cancer
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    World J Surg 29:1497-501; discussion 1502-3. 2005
  2. ncbi Usefulness of thyroglobulin measurement in fine-needle aspiration biopsy specimens for diagnosing cervical lymph node metastasis in patients with papillary thyroid cancer
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    World J Surg 29:483-5. 2005
  3. ncbi A prophylactic infusion of calcium solution reduces the risk of symptomatic hypocalcemia in patients after total thyroidectomy
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori Chuo ku, Kobe, 650 0011, Japan
    World J Surg 30:304-8. 2006
  4. ncbi Papillary microcarcinomas of the thyroid with preoperatively detectable lymph node metastasis show significantly higher aggressive characteristics on immunohistochemical examination
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe City, Japan
    Oncology 68:87-96. 2005
  5. ncbi Expression and cellular localization of p8 protein in thyroid neoplasms
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City 650 0011, Japan
    Cancer Lett 201:237-44. 2003
  6. doi Alternative surgical strategies and favorable outcomes in patients with medullary thyroid carcinoma in Japan: experience of a single institution
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    World J Surg 33:58-66. 2009
  7. ncbi Prognostic significance of extrathyroid extension of papillary thyroid carcinoma: massive but not minimal extension affects the relapse-free survival
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City, 650 0011, Japan
    World J Surg 30:780-6. 2006
  8. ncbi Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT)
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Anticancer Res 25:509-14. 2005
  9. ncbi Ultrasonography as a method of screening for tracheal invasion by papillary thyroid cancer
    Chisato Tomoda
    Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    Surg Today 35:819-22. 2005
  10. ncbi Polo-like kinase 1 expression in medullary carcinoma of the thyroid: its relationship with clinicopathological features
    Yasuhiro Ito
    Kuma Hospital, Kobe, and Department of Pathology, Wakayama Medical University, Japan
    Pathobiology 72:186-90. 2005

Detail Information

Publications69

  1. ncbi Favorable surgical results in 433 elderly patients with papillary thyroid cancer
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    World J Surg 29:1497-501; discussion 1502-3. 2005
    ..Thus surgery is recommended for these patients, if their general status is judged able to tolerate the stress of anesthesia and surgery...
  2. ncbi Usefulness of thyroglobulin measurement in fine-needle aspiration biopsy specimens for diagnosing cervical lymph node metastasis in patients with papillary thyroid cancer
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    World J Surg 29:483-5. 2005
    ..Thyroglobulin measurement in fine-needle aspiration biopsy wash-out is thus a useful technique for diagnosing lymph node metastasis of papillary thyroid cancer...
  3. ncbi A prophylactic infusion of calcium solution reduces the risk of symptomatic hypocalcemia in patients after total thyroidectomy
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori Chuo ku, Kobe, 650 0011, Japan
    World J Surg 30:304-8. 2006
    ..Although intravenous infusion of calcium improves hypocalcemic symptoms, it is unknown whether prophylactic infusion prevents symptoms of postoperative hypocalcemia...
  4. ncbi Papillary microcarcinomas of the thyroid with preoperatively detectable lymph node metastasis show significantly higher aggressive characteristics on immunohistochemical examination
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe City, Japan
    Oncology 68:87-96. 2005
    ..In this study, we investigated difference in the aggressive characteristics of microcarcinoma of this type from various perspectives...
  5. ncbi Expression and cellular localization of p8 protein in thyroid neoplasms
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City 650 0011, Japan
    Cancer Lett 201:237-44. 2003
    ..p8 protein has mitogenic activity and is linked to the development of pancreatic carcinoma. However, little is known about the expression and physiological significance of this protein in other human carcinomas...
  6. doi Alternative surgical strategies and favorable outcomes in patients with medullary thyroid carcinoma in Japan: experience of a single institution
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    World J Surg 33:58-66. 2009
    ..We investigated the clinical outcomes of MTC patients in our department...
  7. ncbi Prognostic significance of extrathyroid extension of papillary thyroid carcinoma: massive but not minimal extension affects the relapse-free survival
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City, 650 0011, Japan
    World J Surg 30:780-6. 2006
    ..In this study, we investigated the prognostic significance of each of the two types of extension...
  8. ncbi Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT)
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Anticancer Res 25:509-14. 2005
    ..In this study, we studied teromerase activity in thyroid tumors using this antibody...
  9. ncbi Ultrasonography as a method of screening for tracheal invasion by papillary thyroid cancer
    Chisato Tomoda
    Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    Surg Today 35:819-22. 2005
    ..To assess the reliability of ultrasonography (US) for detecting tracheal invasion by papillary thyroid cancer (PTC)...
  10. ncbi Polo-like kinase 1 expression in medullary carcinoma of the thyroid: its relationship with clinicopathological features
    Yasuhiro Ito
    Kuma Hospital, Kobe, and Department of Pathology, Wakayama Medical University, Japan
    Pathobiology 72:186-90. 2005
    ..However, its protein expression in human carcinoma has not been studied in depth. In this study, we investigated PLK1 expression in medullary thyroid carcinoma by means of immunohistochemistry...
  11. ncbi S100A4 expression is an early event of papillary carcinoma of the thyroid
    Yasuhiro Ito
    Kuma Hospital, Kobe, Japan
    Oncology 67:397-402. 2004
    ..S100A4 is a calcium-binding protein related to the metastatic potential of carcinoma. In order to elucidate its contribution to the progression of thyroid carcinoma, we investigated S100A4 expression in various thyroid neoplasms...
  12. doi Investigation of the validity of UICC stage grouping of anaplastic carcinoma of the thyroid
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe City, Japan
    Asian J Surg 32:47-50. 2009
    ..Anaplastic thyroid carcinoma arises from differentiated carcinoma and has a very aggressive character. In this study, we investigated the prognosis of patients with anaplastic carcinoma based on UICC stage...
  13. doi Does Hürthle cell carcinoma of the thyroid have a poorer prognosis than ordinary follicular thyroid carcinoma?
    Kiminori Sugino
    Department of Surgery, Ito Hospital, Tokyo, Japan
    Ann Surg Oncol 20:2944-50. 2013
    ..However, little is known about its biological characteristics or clinical behavior. We conducted a retrospective study to determine whether the prognosis of HCC differs from that of ordinary follicular thyroid carcinoma (OFC)...
  14. ncbi 14-3-3 sigma possibly plays a constitutive role in papillary carcinoma, but not in follicular tumor of the thyroid
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Cancer Lett 200:161-6. 2003
    ..These results suggest that 14-3-3 sigma plays a constitutive role in papillary carcinoma rather than acting as a cell cycle regulator, whereas it is not required for the occurrence and development of follicular tumor...
  15. ncbi Prevalence and prognosis of familial follicular thyroid carcinoma
    Yasuhiro Ito
    Departments of Surgery, Kuma Hospital, Kobe City, Japan
    Endocr J 55:847-52. 2008
    ..The therapeutic strategy for follicular carcinoma might depend on conventional prognostic factors such as poor differentiation and distant metastasis at diagnosis, but not on whether the carcinoma is familial or sporadic...
  16. ncbi Minimal extrathyroid extension does not affect the relapse-free survival of patients with papillary thyroid carcinoma measuring 4 cm or less over the age of 45 years
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Surg Today 36:12-8. 2006
    ..In this study, we investigated whether this upgrading is appropriate for papillary thyroid carcinoma...
  17. ncbi Prognosis of patients with papillary carcinoma showing anaplastic transformation in regional lymph nodes that were curatively resected
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, Kobe City, Japan
    Endocr J 55:985-9. 2008
    ..It is therefore suggested that long-term survival can be expected for patients with differentiated carcinoma showing anaplastic transformation in the lymph node if the lesions can be curatively resected...
  18. ncbi Survivin expression is significantly linked to the dedifferentiation of thyroid carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe 650 0011, Japan
    Oncol Rep 10:1337-40. 2003
    ..0001). These results suggest that survivin is strongly related to the dedifferentiation of thyroid carcinoma...
  19. ncbi Expression of Jun activation domain-binding protein 1 and p27 (Kip1) in thyroid medullary carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe, Japan
    Pathology 37:216-9. 2005
    ..In this study, we investigated the expression of these proteins in medullary thyroid carcinoma...
  20. doi Biological behavior and prognosis of familial papillary thyroid carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe City, Japan
    Surgery 145:100-5. 2009
    ..In this study, we investigated the prevalence of familial papillary carcinoma and its biological behavior...
  21. ncbi Caveolin-1 and 14-3-3 sigma expression in follicular variant of thyroid papillary carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, Kobe, Japan
    Pathol Res Pract 201:545-9. 2005
    ..0001). These findings suggest that caveolin-1 and 14-3-3 sigma positively or negatively regulate the development of FVPC but not that of FC, reflecting the difference of biological characteristics of these two types of carcinoma...
  22. doi Biological behavior and prognosis of encapsulated papillary carcinoma of the thyroid: experience of a Japanese hospital for thyroid care
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    World J Surg 32:1789-94. 2008
    ..A subtype of papillary thyroid carcinoma that is totally surrounded by a fibrous capsule is designated an encapsulated carcinoma. In this study, we investigated the biologic behavior and prognosis of this type of carcinoma...
  23. ncbi Expression of cdc25B and cdc25A in medullary thyroid carcinoma: cdc25B expression level predicts a poor prognosis
    Yasuhiro Ito
    Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Cancer Lett 229:291-7. 2005
    ..These findings suggest that cdc25B can be regarded as having prognostic significance and as a novel marker of biologically aggressive characteristics in this carcinoma...
  24. ncbi S100A9 expression is significantly linked to dedifferentiation of thyroid carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, Kobe, Japan
    Pathol Res Pract 201:551-6. 2005
    ..2%), and greater than 25% in six (31.6%) cases. It is therefore suggested that S100A4 protein plays an important role in thyroid carcinoma dedifferentiation, and can be considered a novel characteristic of undifferentiated carcinoma...
  25. ncbi KAI1 expression in thyroid neoplasms: its linkage with clinicopathologic features in papillary carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe, Japan
    Pathol Res Pract 199:79-83. 2003
    ..2% of the cases overexpressed this gene. These results suggest that KAI1 down-regulation is significantly related to the progression of papillary carcinoma, including lymph node metastasis, and its anaplastic transformation...
  26. ncbi Prognosis of patients with papillary thyroid carcinoma having clinically apparent metastasis to the lateral compartment
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, Kobe, Hyogo, Japan
    Endocr J 56:759-66. 2009
    ....
  27. ncbi Ultrasonographically and anatomopathologically detectable node metastases in the lateral compartment as indicators of worse relapse-free survival in patients with papillary thyroid carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, Kobe, Japan
    World J Surg 29:917-20. 2005
    ..1-2.0 cm. These findings suggest that US-detectable lateral metastasis predicts a worse RFS for patients regardless of tumor size, and AP-detectable metastasis affects the RFS of patients with tumors >2 cm...
  28. ncbi Maspin expression is directly associated with biological aggressiveness of thyroid carcinoma
    Yasuhiro Ito
    Kuma Hospital, Kobe, Japan
    Thyroid 14:13-8. 2004
    ..Further studies regarding the function of maspin in this carcinoma are required...
  29. ncbi Papillary microcarcinoma of the thyroid: how should it be treated?
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, 650 0011 Kobe City, Japan
    World J Surg 28:1115-21. 2004
    ....
  30. doi Prevalence and biological behaviour of variants of papillary thyroid carcinoma: experience at a single institute
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe City, Japan
    Pathology 40:617-22. 2008
    ..In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma...
  31. ncbi Expression of alpha1,6-fucosyltransferase (FUT8) in papillary carcinoma of the thyroid: its linkage to biological aggressiveness and anaplastic transformation
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Cancer Lett 200:167-72. 2003
    ..These results suggest that FUT8 expression may be a key factor in the progression of thyroid papillary carcinomas, but not follicular carcinomas, and decreases in FUT8 expression might be linked to anaplastic transformation...
  32. ncbi Ill-defined edge on ultrasonographic examination can be a marker of aggressive characteristic of papillary thyroid microcarcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City 650 0011, Japan
    World J Surg 29:1007-11; discussion 1011-2. 2005
    ..These findings suggest that an ill-defined tumor edge is an important US feature of biologically aggressive PMC. We should carefully follow such patients, regardless of the therapeutic strategy, observation, or surgical treatment chosen...
  33. ncbi Decreased expression of p107 is correlated with anaplastic transformation in papillary carcinoma of the thyroid
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Anticancer Res 23:3819-24. 2003
    ..However, our knowledge about the expression and physiological role of the third member of this family, p107, remains poor. We therefore investigated p107 expression in various thyroid neoplasms...
  34. doi Outcomes and prognostic factors of 251 patients with minimally invasive follicular thyroid carcinoma
    Kiminori Sugino
    Department of Surgery, Ito Hospital, Tokyo, Japan
    Thyroid 22:798-804. 2012
    ..The histological diagnosis of minimally invasive FTC is often made after lobectomy. The aim of this study was to determine the factors associated with the development of distant metastases in patients with minimally invasive FTC...
  35. ncbi Distant and lymph node metastases of thyroid nodules with no pathological evidence of malignancy: a limitation of pathological examination
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe City, Japan
    Endocr J 55:889-94. 2008
    ..Pathological diagnosis of thyroid nodules has limitations, and cases diagnosed as benign nodular goiter should still undergo careful follow-up...
  36. ncbi Occult papillary thyroid carcinoma: diagnostic and clinical implications in the era of routine ultrasonography
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City 650 0011, Japan
    World J Surg 32:1955-60. 2008
    ..In this study we investigated the prevalence and clinicopathologic features, including prognosis, of occult papillary carcinoma...
  37. doi Local prognosis of patients with papillary thyroid carcinoma who were intra-operatively diagnosed as having minimal invasion of the trachea: a 17-year experience in a single institute
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Chuo Ku, Kobe City, Japan
    Asian J Surg 32:102-8. 2009
    ..In this study, we investigated the local prognosis of patients who were intra-operatively diagnosed as having minimal tracheal invasion...
  38. ncbi Prognosis after reoperation for local recurrence of papillary thyroid carcinoma
    Takashi Uruno
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Surg Today 34:891-5. 2004
    ..To investigate the factors associated with a favorable prognosis after reoperation for local recurrent papillary thyroid carcinoma (PTC), we reviewed 45 patients who underwent surgery for first local recurrence of PTC...
  39. ncbi Phosphorylation and inactivation of Tob contributes to the progression of papillary carcinoma of the thyroid
    Yasuhiro Ito
    Kuma Hospital, Kobe 650 0011, Japan
    Cancer Lett 220:237-42. 2005
    ....
  40. ncbi Decreased expression of cyclin G2 is significantly linked to the malignant transformation of papillary carcinoma of the thyroid
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Anticancer Res 23:2335-8. 2003
    ..However, little is known about the cyclin G2 expression in human carcinomas. We thus investigated cyclin G2 expression in human thyroid neoplasms...
  41. ncbi Expression of p8 protein in medullary thyroid carcinoma
    Yasuhiro Ito
    Kuma Hospital, Kobe, Japan
    Anticancer Res 25:3419-23. 2005
    ..The p8 protein is involved in various cells under cellular stress, such as apoptotic stimuli. In this study, p8 protein expression was investigated in human medullary thyroid carcinoma. in order to elucidate its physiological significance...
  42. ncbi Needle tract implantation of papillary thyroid carcinoma after fine-needle aspiration biopsy
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City, 650 0011, Japan
    World J Surg 29:1544-9. 2005
    ..The incidence of implantation was low, and when it did occur, the tumors could be surgically removed without recurrence...
  43. ncbi 14-3-3 sigma possibly plays a constitutive role in papillary carcinoma, but not in follicular tumor of the thyroid
    Yasuhiro Ito
    Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe 650 0011, Japan
    Cancer Lett 196:87-91. 2003
    ..These results suggest that jab1 plays a role in the progression of thyroid carcinomas, especially those of aggressive phenotypes, and it may be responsible for p27 degradation in anaplastic and papillary carcinomas...
  44. ncbi Clinical significance of extrathyroid extension to the parathyroid gland of papillary thyroid carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe City, Japan
    Endocr J 56:251-5. 2009
    ..Since minimal extension did not affect patient prognosis in our series, it is suggested that extension to the parathyroid gland has little clinical significance in PTC...
  45. ncbi Clinical significance of metastasis to the central compartment from papillary microcarcinoma of the thyroid
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City, 650 0011, Japan
    World J Surg 30:91-9. 2006
    ....
  46. ncbi Preoperative administration of excess iodide increases thyroid volume of patients with Graves' disease
    Tomonori Yabuta
    Department of Surgery, Kuma Hospital, Kobe, Japan
    Endocr J 56:371-5. 2009
    ..Surgeons should be careful when preoperatively iodide administering to patients with Graves' disease, especially when the goiter is large...
  47. ncbi Preoperative ultrasonographic examination for lymph node metastasis: usefulness when designing lymph node dissection for papillary microcarcinoma of the thyroid
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, 650 0011 Kobe, Japan
    World J Surg 28:498-501. 2004
    ....
  48. ncbi Transcutaneous iodine absorption in adult patients with thyroid cancer disinfected with povidone-iodine at operation
    Chisato Tomoda
    Kuma Hospital, Kobe, Japan
    Thyroid 15:600-3. 2005
    ..In conclusion, a large amount of povidone-iodine was absorbed through healthy skin even in adults. This may possibly interfere with scintigraphy or radioactive iodine treatment, or cause thyroid disinfection in susceptible patients...
  49. ncbi Changes in the thyroid function of Graves' disease patients treated by subtotal thyroidectomy
    Kiminori Sugino
    Department of Surgery, Ito Hospital, Tokyo, Japan
    Endocr J 59:1115-20. 2012
    ..Because thyroid function after subtotal thyroidectomy is unstable and reduces quality of life, subtotal thyroidectomy is concluded not to be suitable as a standard surgical procedure for the treatment of Graves' disease...
  50. ncbi BRAF mutation in papillary thyroid carcinoma in a Japanese population: its lack of correlation with high-risk clinicopathological features and disease-free survival of patients
    Yasuhiro Ito
    Kuma Hospital, Kobe, Japan
    Endocr J 56:89-97. 2009
    ....
  51. ncbi An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid
    Yasuhiro Ito
    Kuma Hospital, Shimoyamate dori, Kobe City, Japan
    Thyroid 13:381-7. 2003
    ....
  52. ncbi Cribriform-morular variant of papillary thyroid carcinoma: clue to early detection of familial adenomatous polyposis-associated colon cancer
    Chisato Tomoda
    Kuma Hospital, 8 2 535 Shimoyamate dori, Chuo Ku, 650 0011 Kobe, Japan
    World J Surg 28:886-9. 2004
    ..The histopathology of CMV in patients with PTC should arouse a suspicion of FAP, especially if there are multiple tumors. This finding can lead to early detection of colon cancer...
  53. ncbi Reevaluation of stringent low iodine diet in outpatient preparation for radioiodine examination and therapy
    Chisato Tomoda
    Kuma Hospital, Shimoyamate dori, Kobe, Japan
    Endocr J 52:237-40. 2005
    ..Our self-managed, outpatient LID successfully induced iodine deficiency, and two-week LID may be recommended for preparation in radioiodine study and therapy for thyroid cancer...
  54. doi Induction chemotherapy with weekly paclitaxel administration for anaplastic thyroid carcinoma
    Takuya Higashiyama
    Department of Surgery, Kuma Hospital, Kobe, Japan
    Thyroid 20:7-14. 2010
    ..Our objective was to investigate the effectiveness of weekly paclitaxel administered as induction chemotherapy and to establish novel therapeutic strategies for ATC...
  55. ncbi Y-box binding protein expression in thyroid neoplasms: its linkage with anaplastic transformation
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe, Japan
    Pathol Int 53:429-33. 2003
    ..These findings suggest that YB-1 plays a role in regulating the transcription as well as translation of genes contributing to the anaplastic transformation of thyroid carcinoma...
  56. ncbi Diagnostic accuracy of fine needle aspiration biopsy cytology and ultrasonography in patients with thyroid nodules diagnosed as benign or indeterminate before thyroidectomy
    Kiminori Sugino
    Department of Surgery, Ito Hospital, Tokyo 150 8308, Japan
    Endocr J 60:375-82. 2013
    ..FNABC has been the mainstay for the preoperative evaluation of thyroid nodule. The results of this study showed that US can also be a useful tool for diagnosing FTC...
  57. ncbi Changes in serum TSH receptor antibody (TRAb) values in patients with Graves' disease after total or subtotal thyroidectomy
    Yuuki Takamura
    Kuma Hospital, Kobe, Japan
    Endocr J 50:595-601. 2003
    ..TT is a treatment option for Graves' disease, especially in patients with a high TRAb value who wish to have children or who have Graves' opthalmopathy...
  58. ncbi Stretching exercises to reduce symptoms of postoperative neck discomfort after thyroid surgery: prospective randomized study
    Yuuki Takamura
    Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    World J Surg 29:775-9. 2005
    ..6 +/- 2.3 tablets, mean +/- SD) than in the control group (3.1 +/- 3.8 tablets). The stretching exercise had effectively reduced postoperative neck symptoms and also reduced the use of analgesics after thyroid surgery...
  59. ncbi Sensitivity and specificity of intraoperative recurrent laryngeal nerve stimulation test for predicting vocal cord palsy after thyroid surgery
    Chisato Tomoda
    Kuma Hospital, 8 2 35 Shimoyamate dori, Chuo Ku, Kobe, 650 0011, Japan
    World J Surg 30:1230-3. 2006
    ....
  60. ncbi Expression of p8 protein in breast carcinoma; an inverse relationship with apoptosis
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, Kobe City, Japan
    Anticancer Res 25:833-7. 2005
    ..P8 is a transcription factor and its expression is elevated in response to apoptotic stimuli. However, p8 in human carcinoma tissue has not been investigated in depth. In this study, we investigated p8 expression in breast carcinoma...
  61. ncbi Follicular thyroid carcinoma with distant metastasis: outcome and prognostic factor
    Kiminori Sugino
    Department of Surgery, Ito Hospital, Tokyo 150 8308, Japan
    Endocr J 61:273-9. 2014
    ..In this study, we could not show RI therapy, EBRT or surgical treatment for DM had an impact on the outcome. ..
  62. ncbi Prevalence and prognostic significance of poor differentiation and tall cell variant in papillary carcinoma in Japan
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe Cit 650 0011, Japan
    World J Surg 32:1535-43; discussion 1544-5. 2008
    ....
  63. ncbi Computed tomography scan under a trumpet maneuver to demonstrate piriform sinus fistulae in patients with acute suppurative thyroiditis
    Akira Miyauchi
    Department of Surgery, Kuma Hospital, Kobe, Japan
    Thyroid 15:1409-13. 2005
  64. ncbi Expression of cdc25A and cdc25B phosphatase in breast carcinoma
    Yasuhiro Ito
    Department of Surgery, Kuma Hospital, 8 2 35, Shimoyamate dori, Chuo Ku, Kobe City, 650 0011, Japan
    Breast Cancer 11:295-300. 2004
    ..In this study, we investigated the expression of these phosphatases in breast carcinoma to elucidate their significance...
  65. ncbi p130 expression in thyroid neoplasms: its linkage with tumor size and dedifferentiation
    Yasuhiro Ito
    Kuma Hospital, Kobe, Japan
    Cancer Lett 192:83-7. 2003
    ..3% of cases overexpressed this protein. These findings suggest that: (1) reduced p130 expression may contribute to the aggressive character of anplastic carcinoma; and (2) p130 may specify the growth characteristics of microcarcinoma...
  66. doi Prognosis and prognostic factors for distant metastases and tumor mortality in follicular thyroid carcinoma
    Kiminori Sugino
    Department of Surgery, Ito Hospital, Tokyo, Japan
    Thyroid 21:751-7. 2011
    ..In this study, we attempted to identify the risk factors for distant metastases in FTC...
  67. doi Preparation of thyroid tumor cells in aspiration biopsies for aspiration biopsy nucleic acid diagnosis
    Toru Takano
    Department of Laboratory Medicine, Osaka University Graduate School of Medicine, D2, 2 2 Yamadaoka, Osaka 565 0871, Suita, Japan
    Head Neck 30:983-90. 2008
    ..However, because of the interference by the simultaneously aspirated peripheral blood cells or infiltrating lymphocytes, the precise measurement of the T/G ratio in aspirates is difficult...
  68. ncbi Increased expression of valosin-containing protein (p97) is correlated with disease recurrence in follicular thyroid cancer
    Shinji Yamamoto
    Department of Surgery and Clinical Oncology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, 565 0871, Japan
    Ann Surg Oncol 12:925-34. 2005
    ..In this study, the correlation of VCP expression with the prognosis of differentiated thyroid carcinoma was examined...
  69. ncbi Haplotype analysis reveals founder effects of thyroglobulin gene mutations C1058R and C1977S in Japan
    Akira Hishinuma
    Department of Clinical Laboratory Medicine, Dokkyo University School of Medicine, Mibu, Tochigi 321 0293, Japan
    J Clin Endocrinol Metab 91:3100-4. 2006
    ..However, an increasing number of patients with Tg mutations, who are euthyroid to mildly hypothyroid, have been identified in Japan...