Research Topics
Species | Hiromi KoisoSummaryCountry: Japan Publications
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Publications
Quantitative analysis of Cyclin D1 and CD23 expression in mantle cell lymphoma and B-chronic lymphocytic leukemiaHiromi Koiso
Third Department of Internal Medicine, Gunma University School of Medicine, 3 39 15 Showa cho, Maebashi, Gunma, Japan
Leuk Res 26:809-15. 2002..RQ-PCR allows rapid, simple and accurate quantification of CyD1 and CD23 expression, even from small samples, and is thus useful for the diagnosis of MCL and CLL...
Characterization of immunoglobulin heavy and light chain gene expression in chronic lymphocytic leukemia and related disordersHirotaka Nakahashi
Department of Medicine and Clinical Science, Graduate School of Medicine, Gunma University, Gunma, Japan
Cancer Sci 100:671-7. 2009..We found that two patients with chronic lymphocytic leukemia and the patient with splenic marginal zone lymphoma expressed IGHV4-39/IGKV1-39 and IGHV1-69/IGKV3-20, respectively, which belong to these subsets...
Long-term follow-up of EBV-positive lymphoproliferative disorders in a patient with systemic lupus erythematosusNorifumi Tsukamoto
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
Med Mol Morphol 44:237-41. 2011..The current findings illustrate the natural progression in a patient with a long-term history of EBV(+) B-cell LPD in which the immunodeficiency was caused by SLE and probably her aging, which together resulted in histological change...
Age-related epstein-barr virus-positive lymphoproliferative disorders of the orbit and maxillary sinus : a case reportTakeki Mitsui
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Japan
J Clin Exp Hematop 52:205-9. 2012..Owing to the similarity in morphology, higher frequency at extranodal sites and poor prognosis, aEBVBLPD represents a differential diagnostic issue from classical Hodgkin's lymphoma when Reed-Sternberg cells are positive for EBV...
Follicular lymphoma presenting with marked splenomegaly: report of three casesHiromi Koiso
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma University Hospital, Maebashi, Japan
Acta Haematol 128:47-52. 2012..Tumor cells were positive for CD10, CD20, bcl-2, and bcl-6. Since these cases are clinically similar to splenic marginal zone lymphoma, recognition of this disease and selection of the appropriate therapy are needed...
Interleukin-17F gene polymorphism in patients with chronic immune thrombocytopeniaTakayuki Saitoh
Onclology Center, Gunma University Hospital Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Showa machi 3 39 15, Maebashi, Gunma, Japan
Eur J Haematol 87:253-8. 2011..We investigated the association between chronic ITP and the frequency of the single-nucleotide polymorphism rs763780 (7488T/C), which causes a His-to-Arg substitution at amino acid 161...
TCL1A gene involvement in T-cell prolymphocytic leukemia in Japanese patientsAkihiko Yokohama
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
Int J Hematol 95:77-85. 2012..Expression and/or rearrangement of TCL1A may, therefore, be a useful marker for diagnosing T-PLL, regardless of chromosomal abnormalities...
Circulating plasmacytoid dendritic cells in patients with primary and Helicobacter pylori-associated immune thrombocytopeniaAkio Saito
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Gunma
Eur J Haematol 88:340-9. 2012..Although dysfunction of multiple aspects of cellular immunity is considered to be important in the pathogenesis of ITP, it has not been clarified which cell types play a principal role...
Successful treatment of autoimmune hemolytic anemia associated with multicentric Castleman disease by anti-interleukin-6 receptor antibody (tocilizumab) therapyAkinori Yuzuriha
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Japan
Acta Haematol 126:147-50. 2011..Anti-IL-6 receptor antibody treatment could be an attractive therapeutic approach for AIHA associated with MCD...
Distinctive immunoglobulin VH gene usage in Japanese patients with chronic lymphocytic leukemiaHiromi Koiso
Department of Medicine and Clinical Science, Graduate School of Medicine, Gunma University, Gunma, Japan
Leuk Res 30:272-6. 2006..Only one of these patients used V(H)1-69. The finding is in striking contrast to data from western countries, where the frequency of CLL expressing V(H)1-69 ranges from 12 to 21%...
Low burden of a JAK2-V617F mutated clone in monoclonal haematopoiesis in a Japanese woman with Budd-Chiari syndromeKohtaro Toyama
Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
Int J Hematol 89:517-22. 2009..These results suggest that the JAK2-V617F mutation occurs after the onset of monoclonal haematopoiesis; thus the V617F mutation of JAK2 may not be the primary event in the induction of BCS...
