Takako Ujihara

Summary

Affiliation: Kochi University
Country: Japan

Publications

  1. ncbi request reprint Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases
    Shigenobu Matsuzaki
    Department of Molecular Microbiology and Infections, Kochi Medical School, Kohasu, Nankoku, Japan
    J Infect Chemother 11:211-9. 2005
  2. doi request reprint Isolation and characterization of a novel Staphylococcus aureus bacteriophage, phiMR25, and its therapeutic potential
    Hiroshi Hoshiba
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi 783 8505, Japan
    Arch Virol 155:545-52. 2010
  3. doi request reprint Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP10
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Kohasu, Oko cho, Nankoku, Kochi, 783 8505, Japan
    Arch Virol 157:733-8. 2012
  4. doi request reprint Morphological and genetic analysis of three bacteriophages of Serratia marcescens isolated from environmental water
    Kenshi Matsushita
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 291:201-8. 2009
  5. doi request reprint Tail-associated structural protein gp61 of Staphylococcus aureus phage phi MR11 has bifunctional lytic activity
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 284:9-16. 2008
  6. ncbi request reprint Efficient elimination of multidrug-resistant Staphylococcus aureus by cloned lysin derived from bacteriophage phi MR11
    Mohammad Rashel
    Department of Biochemistry, Kochi Medical School, Nankoku 783 8505, Japan
    J Infect Dis 196:1237-47. 2007
  7. doi request reprint A novel site-specific recombination system derived from bacteriophage phiMR11
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Kohasu Oko cho, Nankoku, Kochi 783 8505, Japan
    Biochem Biophys Res Commun 368:192-8. 2008
  8. pmc Characterization of lytic enzyme open reading frame 9 (ORF9) derived from Enterococcus faecalis bacteriophage phiEF24C
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Nankoku City, Kochi, Japan
    Appl Environ Microbiol 77:580-5. 2011
  9. doi request reprint Presence of Merkel cell polyomavirus in Japanese cutaneous squamous cell carcinoma
    Masanao Murakami
    Department of Microbiology and Infection, Kochi Medical School, Kochi University, Nankoku, Kochi 783 8505, Japan
    J Clin Virol 50:37-41. 2011
  10. pmc High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles
    Takuma Higuchi
    Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi, Japan
    PLoS ONE 7:e43340. 2012

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases
    Shigenobu Matsuzaki
    Department of Molecular Microbiology and Infections, Kochi Medical School, Kohasu, Nankoku, Japan
    J Infect Chemother 11:211-9. 2005
    ..Phage therapy will compensate for unavoidable complications of chemotherapy such as the appearance of multidrug resistance or substituted microbism...
  2. doi request reprint Isolation and characterization of a novel Staphylococcus aureus bacteriophage, phiMR25, and its therapeutic potential
    Hiroshi Hoshiba
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi 783 8505, Japan
    Arch Virol 155:545-52. 2010
    ..aureus, as was the case for phiMR11. These results suggest that phiMR25 could be another candidate phage to treat S. aureus infection...
  3. doi request reprint Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP10
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Kohasu, Oko cho, Nankoku, Kochi, 783 8505, Japan
    Arch Virol 157:733-8. 2012
    ..aeruginosa. Phage KPP10 is considered to be suitable for therapeutic purposes because it is a lytic phage without ORF-encoded pathogenicity or a lysogenization factors...
  4. doi request reprint Morphological and genetic analysis of three bacteriophages of Serratia marcescens isolated from environmental water
    Kenshi Matsushita
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 291:201-8. 2009
    ..Both Smp14 and phiEco32 have been reported as potential therapeutic phages. These results suggest that KSP90 and KSP100 may be candidate therapeutic phages to control S. marcescens infection...
  5. doi request reprint Tail-associated structural protein gp61 of Staphylococcus aureus phage phi MR11 has bifunctional lytic activity
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 284:9-16. 2008
    ..This is the first report of the presence of a tail-associated virion protein that acts as a lysin, in an S. aureus phage...
  6. ncbi request reprint Efficient elimination of multidrug-resistant Staphylococcus aureus by cloned lysin derived from bacteriophage phi MR11
    Mohammad Rashel
    Department of Biochemistry, Kochi Medical School, Nankoku 783 8505, Japan
    J Infect Dis 196:1237-47. 2007
    ..These results indicate that MV-L might be useful as a powerful therapeutic agent against multidrug-resistant S. aureus infections...
  7. doi request reprint A novel site-specific recombination system derived from bacteriophage phiMR11
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Kohasu Oko cho, Nankoku, Kochi 783 8505, Japan
    Biochem Biophys Res Commun 368:192-8. 2008
    ..In in vitro assays using crude or purified integrase, only buffer and substrate DNAs were required for the recombination reaction, indicating that other bacterially encoded factors are not essential for activity...
  8. pmc Characterization of lytic enzyme open reading frame 9 (ORF9) derived from Enterococcus faecalis bacteriophage phiEF24C
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Nankoku City, Kochi, Japan
    Appl Environ Microbiol 77:580-5. 2011
    ..These results suggested that ORF9 is an endolysin of phage ¤ćEF24C and can be a therapeutic alternative to antibiotics...
  9. doi request reprint Presence of Merkel cell polyomavirus in Japanese cutaneous squamous cell carcinoma
    Masanao Murakami
    Department of Microbiology and Infection, Kochi Medical School, Kochi University, Nankoku, Kochi 783 8505, Japan
    J Clin Virol 50:37-41. 2011
    ..Merkel cell polyomavirus (MCPyV) was first identified in Merkel cell carcinoma (MCC) as a new tumor virus. Studies have also reported differing frequencies of MCPyV detection in other skin cancers in western countries...
  10. pmc High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles
    Takuma Higuchi
    Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi, Japan
    PLoS ONE 7:e43340. 2012
    ....
  11. ncbi request reprint Experimental protection of mice against lethal Staphylococcus aureus infection by novel bacteriophage phi MR11
    Shigenobu Matsuzaki
    Department of Microbiology, Kochi Medical School, Kochi, Japan
    J Infect Dis 187:613-24. 2003
    ..These results uphold the efficacy of phage therapy against pernicious S. aureus infections in humans and suggest that phi MR11 may be a potential prototype for gene-modified, advanced therapeutic S. aureus phages...