Takako Ujihara

Summary

Affiliation: Kochi University
Country: Japan

Publications

  1. ncbi Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases
    Shigenobu Matsuzaki
    Department of Molecular Microbiology and Infections, Kochi Medical School, Kohasu, Nankoku, Japan
    J Infect Chemother 11:211-9. 2005
  2. ncbi Isolation and characterization of a novel Staphylococcus aureus bacteriophage, phiMR25, and its therapeutic potential
    Hiroshi Hoshiba
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi 783 8505, Japan
    Arch Virol 155:545-52. 2010
  3. ncbi Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP10
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Kohasu, Oko cho, Nankoku, Kochi, 783 8505, Japan
    Arch Virol 157:733-8. 2012
  4. ncbi Morphological and genetic analysis of three bacteriophages of Serratia marcescens isolated from environmental water
    Kenshi Matsushita
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 291:201-8. 2009
  5. ncbi Tail-associated structural protein gp61 of Staphylococcus aureus phage phi MR11 has bifunctional lytic activity
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 284:9-16. 2008
  6. ncbi Efficient elimination of multidrug-resistant Staphylococcus aureus by cloned lysin derived from bacteriophage phi MR11
    Mohammad Rashel
    Department of Biochemistry, Kochi Medical School, Nankoku 783 8505, Japan
    J Infect Dis 196:1237-47. 2007
  7. ncbi A novel site-specific recombination system derived from bacteriophage phiMR11
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Kohasu Oko cho, Nankoku, Kochi 783 8505, Japan
    Biochem Biophys Res Commun 368:192-8. 2008
  8. ncbi Characterization of lytic enzyme open reading frame 9 (ORF9) derived from Enterococcus faecalis bacteriophage phiEF24C
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Nankoku City, Kochi, Japan
    Appl Environ Microbiol 77:580-5. 2011
  9. ncbi Presence of Merkel cell polyomavirus in Japanese cutaneous squamous cell carcinoma
    Masanao Murakami
    Department of Microbiology and Infection, Kochi Medical School, Kochi University, Nankoku, Kochi 783 8505, Japan
    J Clin Virol 50:37-41. 2011
  10. ncbi High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles
    Takuma Higuchi
    Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi, Japan
    PLoS ONE 7:e43340. 2012

Collaborators

  • Jumpei Uchiyama
  • Hiroshi Wakiguchi
  • Masanori Daibata
  • Shosuke Imai
  • Atsuki Fukushima
  • Shuji Sakamoto
  • Keiichi Hiramatsu
  • Masahiko Ikeuchi
  • Motoyuki Sugai
  • Shigenobu Matsuzaki
  • Mohammad Rashel
  • Hiroshi Hoshiba
  • Asako Muraoka
  • Shigeyoshi Sugihara
  • Takuma Higuchi
  • Masanao Murakami
  • Ken Ichi Yagyu
  • Shin ichiro Kato
  • Kenshi Matsushita
  • Iyo Takemura
  • Koichi Honke
  • Masayuki Kuroda
  • Shoshiro Okada
  • Shoko Kai
  • Keiko Morisawa
  • Yoshihiko Kakinuma
  • Yasutoshi Agata
  • Waka Ishida
  • Taketoshi Taniguchi
  • Hiroshi Todaka
  • Yasunori Sugiyama
  • Eunsup Chi
  • Masafumi Ono
  • Masayuki Tsuda
  • Hideki Nakajima
  • Takuya Ikawa
  • Masayuki Imajoh
  • Shigetoshi Sano
  • Mikio Kamioka
  • Yuiko Nemoto
  • Hiroyoshi Takatsuji
  • Yoshio Uehara
  • Ken-Ichi Yagyu
  • Shu Kuramoto
  • Mikiya Fujieda
  • Toshikazu Tani
  • Shingo Sakurai
  • Shigeki Koda
  • Shigeyoshi Fujimoto
  • Zhe Jin
  • Taro Shuin
  • Masaharu Yasuda
  • Yuan Shen
  • M D Nasimuzzaman
  • Hiroshi Nishikawa
  • Tetsuro Sugiura

Detail Information

Publications11

  1. ncbi Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases
    Shigenobu Matsuzaki
    Department of Molecular Microbiology and Infections, Kochi Medical School, Kohasu, Nankoku, Japan
    J Infect Chemother 11:211-9. 2005
    ..Phage therapy will compensate for unavoidable complications of chemotherapy such as the appearance of multidrug resistance or substituted microbism...
  2. ncbi Isolation and characterization of a novel Staphylococcus aureus bacteriophage, phiMR25, and its therapeutic potential
    Hiroshi Hoshiba
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi 783 8505, Japan
    Arch Virol 155:545-52. 2010
    ..aureus, as was the case for phiMR11. These results suggest that phiMR25 could be another candidate phage to treat S. aureus infection...
  3. ncbi Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP10
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Kohasu, Oko cho, Nankoku, Kochi, 783 8505, Japan
    Arch Virol 157:733-8. 2012
    ..aeruginosa. Phage KPP10 is considered to be suitable for therapeutic purposes because it is a lytic phage without ORF-encoded pathogenicity or a lysogenization factors...
  4. ncbi Morphological and genetic analysis of three bacteriophages of Serratia marcescens isolated from environmental water
    Kenshi Matsushita
    Department of Pediatrics, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 291:201-8. 2009
    ..Both Smp14 and phiEco32 have been reported as potential therapeutic phages. These results suggest that KSP90 and KSP100 may be candidate therapeutic phages to control S. marcescens infection...
  5. ncbi Tail-associated structural protein gp61 of Staphylococcus aureus phage phi MR11 has bifunctional lytic activity
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Nankoku, Kochi, Japan
    FEMS Microbiol Lett 284:9-16. 2008
    ..This is the first report of the presence of a tail-associated virion protein that acts as a lysin, in an S. aureus phage...
  6. ncbi Efficient elimination of multidrug-resistant Staphylococcus aureus by cloned lysin derived from bacteriophage phi MR11
    Mohammad Rashel
    Department of Biochemistry, Kochi Medical School, Nankoku 783 8505, Japan
    J Infect Dis 196:1237-47. 2007
    ..These results indicate that MV-L might be useful as a powerful therapeutic agent against multidrug-resistant S. aureus infections...
  7. ncbi A novel site-specific recombination system derived from bacteriophage phiMR11
    Mohammad Rashel
    Department of Microbiology and Infection, Kochi Medical School, Kohasu Oko cho, Nankoku, Kochi 783 8505, Japan
    Biochem Biophys Res Commun 368:192-8. 2008
    ..In in vitro assays using crude or purified integrase, only buffer and substrate DNAs were required for the recombination reaction, indicating that other bacterially encoded factors are not essential for activity...
  8. ncbi Characterization of lytic enzyme open reading frame 9 (ORF9) derived from Enterococcus faecalis bacteriophage phiEF24C
    Jumpei Uchiyama
    Department of Microbiology and Infection, Faculty of Medicine, Kochi University, Nankoku City, Kochi, Japan
    Appl Environ Microbiol 77:580-5. 2011
    ..These results suggested that ORF9 is an endolysin of phage φEF24C and can be a therapeutic alternative to antibiotics...
  9. ncbi Presence of Merkel cell polyomavirus in Japanese cutaneous squamous cell carcinoma
    Masanao Murakami
    Department of Microbiology and Infection, Kochi Medical School, Kochi University, Nankoku, Kochi 783 8505, Japan
    J Clin Virol 50:37-41. 2011
    ..Merkel cell polyomavirus (MCPyV) was first identified in Merkel cell carcinoma (MCC) as a new tumor virus. Studies have also reported differing frequencies of MCPyV detection in other skin cancers in western countries...
  10. ncbi High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles
    Takuma Higuchi
    Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi, Japan
    PLoS ONE 7:e43340. 2012
    ....
  11. ncbi Experimental protection of mice against lethal Staphylococcus aureus infection by novel bacteriophage phi MR11
    Shigenobu Matsuzaki
    Department of Microbiology, Kochi Medical School, Kochi, Japan
    J Infect Dis 187:613-24. 2003
    ..These results uphold the efficacy of phage therapy against pernicious S. aureus infections in humans and suggest that phi MR11 may be a potential prototype for gene-modified, advanced therapeutic S. aureus phages...