Hiroyuki Yamamoto

Summary

Affiliation: Kobe University
Country: Japan

Publications

  1. ncbi request reprint The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon
    Shuichi Kani
    Department of Genome Sciences, Faculty of Medical Sciences, Graduate School of Medicine, Kobe University, Kobe 650 0017, Japan
    J Biol Chem 279:50102-9. 2004
  2. ncbi request reprint A novel RDH5 gene mutation in a patient with fundus albipunctatus presenting with macular atrophy and fading white dots
    Hiroyuki Yamamoto
    Departments of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Japan
    Am J Ophthalmol 136:572-4. 2003
  3. doi request reprint Photodynamic therapy for typical age-related macular degeneration and polypoidal choroidal vasculopathy: a 30-month multicenter study in Hyogo, Japan
    Shigeru Honda
    Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, and Department of Ophthalmology, Kobe City General Hospital, Kobe, Japan
    Jpn J Ophthalmol 53:593-7. 2009
  4. ncbi request reprint A case of POEMS syndrome with cystoid macular edema
    Hisanori Imai
    Department of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Am J Ophthalmol 139:563-6. 2005
  5. doi request reprint Comparative assessment of photodynamic therapy for typical age-related macular degeneration and polypoidal choroidal vasculopathy: a multicenter study in Hyogo prefecture, Japan
    Shigeru Honda
    Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Ophthalmologica 223:333-8. 2009
  6. ncbi request reprint Prediction of postoperative visual outcome based on hole configuration by optical coherence tomography in eyes with idiopathic macular holes
    Sentaro Kusuhara
    Department of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Am J Ophthalmol 138:709-16. 2004
  7. ncbi request reprint Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes
    Gerald A Fishman
    Department of Ophthalmology and Visual Sciences, UIC Eye Center, University of Illinois at Chicago, 60612, USA
    Arch Ophthalmol 122:70-5. 2004
  8. ncbi request reprint Fundus albipunctatus in a 6-year old girl due to compound heterozygous mutations in the RDH5 gene
    Alessandro Iannaccone
    Retinal Degeneration and Ophthalmic Genetics Service, Hamilton Eye Institute, Department of Ophthalmology, University of Tennessee Health Science Center, 930 Madison Avenue, Suite 731, Memphis, TN 38163, USA
    Doc Ophthalmol 115:111-6. 2007
  9. ncbi request reprint Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2
    Hiroyuki Yamamoto
    Department of Physiology and Cell Biology, Faculty of Medical Sciences, Graduate School of Medicine, Kobe University, 7 5 1, Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    Genes Cells 12:1215-23. 2007
  10. ncbi request reprint Identification of a novel substrate for TNFalpha-induced kinase NUAK2
    Hiroyuki Yamamoto
    Department of Medical Information Science, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 365:541-7. 2008

Collaborators

  • Kenji Yamashiro
  • Yasutomo Tsukahara
  • Shigeru Honda
  • Hitoshi Takagi
  • Sotaro Ooto
  • Michiru Nishita
  • Thaddeus Dryja
  • Yuichiro Ogura
  • Alessandro Iannaccone
  • Eliot L Berson
  • Taiji Sakamoto
  • Eiji Shimizu
  • S Charles
  • Robert M W Hofstra
  • Akira Kikuchi
  • Yasushi Adachi
  • Kohzoh Imai
  • Carla Oliveira
  • Katsuhiko Nosho
  • Yasuhisa Shinomura
  • Hiroaki Taniguchi
  • Taiga Takahashi
  • Masashi Mikami
  • Enric Domingo
  • Fumio Itoh
  • Nobuki Miyamoto
  • Akira Negi
  • Yoriko Nakanishi
  • Sentaro Kusuhara
  • Simo Schwartz
  • Raquel Seruca
  • Gerald A Fishman
  • Dror Sharon
  • Hisakazu Kato
  • Masaru Inatani
  • Tadateru Maehata
  • Nobutaka Mitsuda
  • Yoon Jin Lee
  • Miki Kawada
  • Kazuhiko Yoneda
  • Hisanori Imai
  • Manel Armengol
  • Eloi Espin
  • Richard Hamelin
  • Shuichi Kani
  • Takehiko Maeda
  • Hidenobu Tanihara
  • Fumio Shiraga
  • Seiji Takashima
  • Kazuyuki Hirooka
  • Yuka Shimonagano
  • Yasunori Shintani
  • Keiichiro Iwao
  • Keiichi Hizaki
  • Osamu Seguchi
  • Masafumi Kitakaze
  • Miyo Matsumura
  • Atsushi Nakano
  • Satoshi Yamaoka
  • Akiko Ogai
  • Yoshio Hirano
  • Takahiro Kawaji
  • Satoru Yamazaki
  • Shuichiro Higo
  • Chieko Shima
  • Yoshihiro Asano
  • Tetsuo Minamino
  • Masatsugu Hori
  • Mariko Oki
  • Masato Yoshida
  • Sung Youn Kwon
  • David P Carbone
  • Chie Miyamoto
  • Young Soo Shim
  • Ho Il Yoon
  • Sung Koo Han
  • Arisa Imsumran
  • Motoaki Seki
  • Kazuo Shinozaki
  • Wenhua Piao
  • Mi Young Park
  • Choon Taek Lee
  • Akira Iwase
  • Chul Gyu Yoo
  • Young Whan Kim
  • Masaru Ohme-Takagi
  • Jae Ho Lee
  • Masahiro Fujita
  • Akiko Takeda
  • Sachi Dohki

Detail Information

Publications26

  1. ncbi request reprint The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon
    Shuichi Kani
    Department of Genome Sciences, Faculty of Medical Sciences, Graduate School of Medicine, Kobe University, Kobe 650 0017, Japan
    J Biol Chem 279:50102-9. 2004
    ..This indicates that autophosphorylation of Ror2 is required for full activation of its tyrosine kinase activity. These findings demonstrate a novel role for CKIepsilon in the regulation of Ror2 tyrosine kinase...
  2. ncbi request reprint A novel RDH5 gene mutation in a patient with fundus albipunctatus presenting with macular atrophy and fading white dots
    Hiroyuki Yamamoto
    Departments of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Japan
    Am J Ophthalmol 136:572-4. 2003
    ..To report a novel homozygous RDH5 gene mutation in a 76-year-old fundus albipunctatus who developed macular atrophy with the disappearance of white dots...
  3. doi request reprint Photodynamic therapy for typical age-related macular degeneration and polypoidal choroidal vasculopathy: a 30-month multicenter study in Hyogo, Japan
    Shigeru Honda
    Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, and Department of Ophthalmology, Kobe City General Hospital, Kobe, Japan
    Jpn J Ophthalmol 53:593-7. 2009
    ..To evaluate the long-term effects of photodynamic therapy (PDT) on different phenotypes of age-related macular degeneration (AMD): typical AMD (tAMD) and polypoidal choroidal vasculopathy (PCV)...
  4. ncbi request reprint A case of POEMS syndrome with cystoid macular edema
    Hisanori Imai
    Department of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Am J Ophthalmol 139:563-6. 2005
    ..To introduce a case of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome with bilateral cystoid macular edema (CME)...
  5. doi request reprint Comparative assessment of photodynamic therapy for typical age-related macular degeneration and polypoidal choroidal vasculopathy: a multicenter study in Hyogo prefecture, Japan
    Shigeru Honda
    Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Ophthalmologica 223:333-8. 2009
    ..We aimed to evaluate the effects of photodynamic therapy (PDT) on different phenotypes of age-related macular degenerations (AMD): typical AMD (tAMD) and polypoidal choroidal vasculopathy (PCV)...
  6. ncbi request reprint Prediction of postoperative visual outcome based on hole configuration by optical coherence tomography in eyes with idiopathic macular holes
    Sentaro Kusuhara
    Department of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan
    Am J Ophthalmol 138:709-16. 2004
    ..To evaluate whether an index based on hole configuration can be used to predict visual outcome in eyes with idiopathic macular holes...
  7. ncbi request reprint Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes
    Gerald A Fishman
    Department of Ophthalmology and Visual Sciences, UIC Eye Center, University of Illinois at Chicago, 60612, USA
    Arch Ophthalmol 122:70-5. 2004
    ..To evaluate the molecular genetic defects associated with retinitis punctata albescens (RPA) in 5 patients from 3 families with this disease...
  8. ncbi request reprint Fundus albipunctatus in a 6-year old girl due to compound heterozygous mutations in the RDH5 gene
    Alessandro Iannaccone
    Retinal Degeneration and Ophthalmic Genetics Service, Hamilton Eye Institute, Department of Ophthalmology, University of Tennessee Health Science Center, 930 Madison Avenue, Suite 731, Memphis, TN 38163, USA
    Doc Ophthalmol 115:111-6. 2007
    ..The behavior of dark-adapted ERG responses in FA displays characteristics that differ from those of RPA patients, which may be useful to differentiate functionally these two conditions at their common albipunctate stages...
  9. ncbi request reprint Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2
    Hiroyuki Yamamoto
    Department of Physiology and Cell Biology, Faculty of Medical Sciences, Graduate School of Medicine, Kobe University, 7 5 1, Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan
    Genes Cells 12:1215-23. 2007
    ..Moreover, it was found that Wnt5a-induced cell migration can be inhibited by SB216763 or by siRNA-mediated suppression of GSK-3alpha (and GSK-3beta) expression, further emphasizing the role(s) of GSK-3 in Wnt5a-induced signaling...
  10. ncbi request reprint Identification of a novel substrate for TNFalpha-induced kinase NUAK2
    Hiroyuki Yamamoto
    Department of Medical Information Science, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 365:541-7. 2008
    ..These data suggests different phosphorylation and regulation of MYPT1 activity by NUAK2...
  11. ncbi request reprint Identification of p32 as a novel substrate for ATM in heart
    Hisakazu Kato
    Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 366:885-91. 2008
    ..Since p32 is known to regulate mRNA splicing and transcription, p32 phosphorylation by ATM might be a new transcriptional regulatory pathway for specific DNA damage responses in heart...
  12. doi request reprint Intraocular pressure elevation after injection of triamcinolone acetonide: a multicenter retrospective case-control study
    Masaru Inatani
    Department of Ophthalmology and Visual Science, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
    Am J Ophthalmol 145:676-681. 2008
    ..To determine the risk factors for intraocular pressure (IOP) elevation after the injection of triamcinolone acetonide (TA)...
  13. doi request reprint Correlation of laterally spreading type and JC virus with methylator phenotype status in colorectal adenoma
    Katsuhiko Nosho
    First Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo 060 8543, Japan
    Hum Pathol 39:767-75. 2008
    ..In conclusion, among colorectal adenomas, CIMP-high status was determined by BRAF mutation and not by macroscopic type, unlike CIMP-0. JC virus T-Ag may be important in determining methylator phenotype...
  14. doi request reprint Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma
    Hideyasu Takagi
    First Department of Internal Medicine, Sapporo Medical University, S1, W16, Chuo Ku, Sapporo 060 8543, Japan
    J Gastroenterol 43:378-89. 2008
    ..Activation of the Wnt signaling pathway is frequently observed in hepatocellular carcinoma (HCC), though mutation of three of its components, CTNNB1, AXIN1, and AXIN2, is observed substantially less often...
  15. ncbi request reprint Differential expression of angiogenesis-related genes in human gastric cancers with and those without high-frequency microsatellite instability
    Nobuki Miyamoto
    First Department of Internal Medicine, Sapporo Medical University, South 1, West 16, Sapporo, Japan
    Cancer Lett 254:42-53. 2007
    ..The difference may be associated with less aggressive phenotype of these cancers with MSI-H and affect future molecular targeted therapeutics...
  16. pmc NAC transcription factors, NST1 and NST3, are key regulators of the formation of secondary walls in woody tissues of Arabidopsis
    Nobutaka Mitsuda
    Research Institute of Genome Based Biofactory, National Institute of Advanced Industrial Science and Technology, Tsukuba 305 8562, Japan
    Plant Cell 19:270-80. 2007
    ....
  17. ncbi request reprint Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas
    Taiga Takahashi
    First Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
    Mod Pathol 20:139-47. 2007
    ..Epigenetic alterations infrequently occurred in flat-type advanced adenomas, suggesting that they have different genetic and epigenetic alterations from those of protruded-type advanced adenomas...
  18. ncbi request reprint Naloxone-precipitated morphine withdrawal elicits increases in c-fos mRNA expression in restricted regions of the infant rat brain
    Takehiko Maeda
    Department of Pharmacology, Wakayama Medical University, Japan
    Jpn J Pharmacol 90:270-5. 2002
    ....
  19. ncbi request reprint BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency
    Carla Oliveira
    Instituto de Patologia e Imunologia Molecular da Universidade do Porto IPATIMUP, Porto 4200 465, Portugal
    Oncogene 22:9192-6. 2003
    ..Accordingly, our results show evidences that BRAF mutations characterize colon but not gastric tumors with MMR deficiency and are not involved in the tumorigenesis of gastric cancer of the mutator phenotype pathway...
  20. ncbi request reprint Measurement of Pseudomonas aeruginosa multidrug efflux pumps by quantitative real-time polymerase chain reaction
    Kazuhiko Yoneda
    Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, 36 1 Nishi machi, Yonago shi, Tottori ken 683 0805, Japan
    FEMS Microbiol Lett 243:125-31. 2005
    ..Quantitative real-time PCR should be a useful alternative in quantitating expression of multidrug efflux pumps by P. aeruginosa isolates in clinical laboratories...
  21. ncbi request reprint BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes
    Enric Domingo
    Molecular Oncology and Aging Research, Centre d Investigacions en Bioquimica i Biologia Molecular CIBBIM, Hospital Universitari Vall d Hebron, Passeig Vall d Hebron 119 129, Barcelona 08035, Spain
    Oncogene 24:3995-8. 2005
    ..These findings have a potential impact in the genetic testing for HNPCC diagnostics and suggest a potential use of BRAF as exclusion criteria for HNPCC or as a molecular marker of sporadic cancer...
  22. ncbi request reprint Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer
    Carla Oliveira
    Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s n, Porto 4200 465, Portugal
    Oncogene 24:7630-4. 2005
    ....
  23. pmc Involvement of multiple epitope-specific cytotoxic T-lymphocyte responses in vaccine-based control of simian immunodeficiency virus replication in rhesus macaques
    Miki Kawada
    Department of Microbiology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Virol 80:1949-58. 2006
    ....
  24. ncbi request reprint Mutational analysis of beta-catenin and the RAS-RAF signalling pathway in early flat-type colorectal tumours
    Masashi Mikami
    First Department of Internal Medicine, Sapporo Medical University School of Medicine, Chuo Ku, Sapporo 060 8543, Japan
    Eur J Cancer 42:3065-72. 2006
    ..The genetic abnormalities could arise and accumulate in the early stage of colorectal tumourigenesis, and seem to contribute to the development of flat-type tumour...
  25. ncbi request reprint Adenovirus expressing shRNA to IGF-1R enhances the chemosensitivity of lung cancer cell lines by blocking IGF-1 pathway
    Yoon Jin Lee
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute of Medical Research Center, Seoul National University College of Medicine, Seoul 110 744, Republic of Korea
    Lung Cancer 55:279-86. 2007
    ..We believe that this system can be usefully applied to other cancer targets...
  26. ncbi request reprint Mutated alleles of the rod and cone Na-Ca+K-exchanger genes in patients with retinal diseases
    Dror Sharon
    Ocular Molecular Genetics Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 43:1971-9. 2002
    ..To study the possible involvement of the rod (SLC24A1) and cone (SLC24A2) Na-Ca+K exchanger (NCKX) genes in retinal diseases...