Takashi Sasayama

Summary

Affiliation: Kobe University
Country: Japan

Publications

  1. Sasayama T, Nishihara M, Kondoh T, Hosoda K, Kohmura E. MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC. Int J Cancer. 2009;125:1407-13 pubmed publisher
    ..Finally, multifocal lesions on enhanced MRI of 7 malignant gliomas were associated with higher expression levels of miR-10b (p = 0.02). Our data indicated that miR-10b might play some role in the invasion of glioma cells. ..
  2. request reprint
    Sasayama T, Mizukawa K, Sakagami Y, Mizowaki T, Tanaka K, Ohbayashi C, et al. Glioblastoma multiforme associated with klinefelter syndrome. Neurol Med Chir (Tokyo). 2009;49:532-5 pubmed
    ..The abnormal genetic constitution of this patient may have been directly responsible for the poor outcome. ..
  3. Sasayama T, Nakamizo S, Nishihara M, Kawamura A, Tanaka H, Mizukawa K, et al. Cerebrospinal fluid interleukin-10 is a potentially useful biomarker in immunocompetent primary central nervous system lymphoma (PCNSL). Neuro Oncol. 2012;14:368-80 pubmed publisher
    ..37; 95% confidence interval, 0.985-11.528; log-rank, P= .038). These results indicate that the CSF level of IL-10 may be a useful diagnostic and prognostic biomarker in patients with PCNSLs. ..
  4. Minami N, Tanaka K, Kimura H, Hirose T, Mori T, Maeyama M, et al. Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy. BMC Neurol. 2016;16:4 pubmed publisher
    ..Biopsy of the tumor at an early stage is the only way to make the diagnosis conclusively and enable prompt start of treatment. ..
  5. Tanaka H, Sasayama T, Yamashita H, Hara Y, Hayashi S, Yamamoto Y, et al. Rapid tumor growth with glial differentiation of central neurocytoma after stereotactic radiosurgery. J Clin Neurosci. 2016;31:188-92 pubmed publisher
    ..Our case suggests that malignant transition with aberrant angiogenesis and glial differentiation may be attributable to SRS. ..
  6. Kohta M, Sasayama T, Nakai T, Taniguchi M, Nagashima H, Tanaka K, et al. Cisterna magna meningiomas without dural attachment: Report of two cases. Neurol Neurochir Pol. 2017;51:247-251 pubmed publisher
    ..At a 7-year follow-up, no evidence of a recurrence was observed. It is quite difficult to preoperatively diagnose as a cisterna magna meningioma without dural attachment. However, complete removal of the tumor should be achieved. ..
  7. Nagashima H, Sasayama T, Tanaka K, Kyotani K, Sato N, Maeyama M, et al. Myo-inositol concentration in MR spectroscopy for differentiating high grade glioma from primary central nervous system lymphoma. J Neurooncol. 2018;136:317-326 pubmed publisher
    ..In conclusion, noninvasive analysis of mIns using single-voxel MRS may be useful in distinguishing gliomas from other brain tumors, particularly PCNSLs. ..

Detail Information

Publications7

  1. Sasayama T, Nishihara M, Kondoh T, Hosoda K, Kohmura E. MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC. Int J Cancer. 2009;125:1407-13 pubmed publisher
    ..Finally, multifocal lesions on enhanced MRI of 7 malignant gliomas were associated with higher expression levels of miR-10b (p = 0.02). Our data indicated that miR-10b might play some role in the invasion of glioma cells. ..
  2. request reprint
    Sasayama T, Mizukawa K, Sakagami Y, Mizowaki T, Tanaka K, Ohbayashi C, et al. Glioblastoma multiforme associated with klinefelter syndrome. Neurol Med Chir (Tokyo). 2009;49:532-5 pubmed
    ..The abnormal genetic constitution of this patient may have been directly responsible for the poor outcome. ..
  3. Sasayama T, Nakamizo S, Nishihara M, Kawamura A, Tanaka H, Mizukawa K, et al. Cerebrospinal fluid interleukin-10 is a potentially useful biomarker in immunocompetent primary central nervous system lymphoma (PCNSL). Neuro Oncol. 2012;14:368-80 pubmed publisher
    ..37; 95% confidence interval, 0.985-11.528; log-rank, P= .038). These results indicate that the CSF level of IL-10 may be a useful diagnostic and prognostic biomarker in patients with PCNSLs. ..
  4. Minami N, Tanaka K, Kimura H, Hirose T, Mori T, Maeyama M, et al. Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy. BMC Neurol. 2016;16:4 pubmed publisher
    ..Biopsy of the tumor at an early stage is the only way to make the diagnosis conclusively and enable prompt start of treatment. ..
  5. Tanaka H, Sasayama T, Yamashita H, Hara Y, Hayashi S, Yamamoto Y, et al. Rapid tumor growth with glial differentiation of central neurocytoma after stereotactic radiosurgery. J Clin Neurosci. 2016;31:188-92 pubmed publisher
    ..Our case suggests that malignant transition with aberrant angiogenesis and glial differentiation may be attributable to SRS. ..
  6. Kohta M, Sasayama T, Nakai T, Taniguchi M, Nagashima H, Tanaka K, et al. Cisterna magna meningiomas without dural attachment: Report of two cases. Neurol Neurochir Pol. 2017;51:247-251 pubmed publisher
    ..At a 7-year follow-up, no evidence of a recurrence was observed. It is quite difficult to preoperatively diagnose as a cisterna magna meningioma without dural attachment. However, complete removal of the tumor should be achieved. ..
  7. Nagashima H, Sasayama T, Tanaka K, Kyotani K, Sato N, Maeyama M, et al. Myo-inositol concentration in MR spectroscopy for differentiating high grade glioma from primary central nervous system lymphoma. J Neurooncol. 2018;136:317-326 pubmed publisher
    ..In conclusion, noninvasive analysis of mIns using single-voxel MRS may be useful in distinguishing gliomas from other brain tumors, particularly PCNSLs. ..