K Nishina

Summary

Affiliation: Kobe University
Country: Japan

Publications

  1. pmc The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice
    Hiroyuki Miyazaki
    Division of Anesthesiology and Perioperative Medicine, Kobe University Graduate School of Medicine, Chuo Ku, Kobe, Hyogo, 650 0017, Japan
    BMC Nephrol 13:153. 2012
  2. ncbi request reprint Oral clonidine premedication reduces minimum alveolar concentration of sevoflurane for tracheal intubation in children
    K Nishina
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesthesiology 87:1324-7. 1997
  3. ncbi request reprint Effects of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion in children
    K Nishina
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesthesiology 88:922-7. 1998
  4. ncbi request reprint The effects of clonidine and dexmedetomidine on human neutrophil functions
    K Nishina
    Department of Anaesthesiology and Intensive Care Medicine, Kobe University School of Medicine, Japan
    Anesth Analg 88:452-8. 1999
  5. ncbi request reprint Propofol attenuates diaphragmatic dysfunction induced by septic peritonitis in hamsters
    K Mikawa
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesthesiology 94:652-60. 2001
  6. ncbi request reprint ONO1714, a new inducible nitric oxide synthase inhibitor, attenuates sepsis-induced diaphragmatic dysfunction in hamsters
    K Nishina
    Departments of Anaesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kobe, Japan
    Anesth Analg 92:959-66. 2001
  7. ncbi request reprint Attenuation of the cardiovascular and catecholamine responses to tracheal intubation with oral guanabenz
    K Mikawa
    Department of Anaesthesiology, Kobe University School of Medicine, Japan
    Anesth Analg 76:585-91. 1993
  8. ncbi request reprint Oral clonidine premedication does not change efficacy of simulated epidural test dose in sevoflurane-anesthetized children
    M Shiga
    Department of Anesthesiology, Kobe Children s Hospital, Kobe, Japan
    Anesthesiology 93:954-8. 2000
  9. ncbi request reprint The effect of halothane and sevoflurane on fatigue-induced changes in hamster diaphragmatic contractility
    T Kagawa
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesth Analg 86:392-7. 1998
  10. ncbi request reprint Clonidine decreases the dose of thiamylal required to induce anesthesia in children
    K Nishina
    Department of Anaesthesiology, Kobe University School of Medicine, Japan
    Anesth Analg 79:766-8. 1994

Collaborators

  • T Ono
  • M Yoshinaga
  • T Kagawa
  • A Matsukawa
  • Hirohiko Akamatsu
  • K Mikawa
  • H Obara
  • M Shiga
  • Y Niwa
  • Hiroyuki Miyazaki
  • T Uesugi
  • S I Kodama
  • Nobuhiro Maekawa
  • Masaaki Ueki
  • Shunichi Shiozawa
  • N Maekawa
  • Jun Morishita
  • S Furue
  • H Akamarsu
  • S Kodama
  • M Ueno
  • Y Chikazawa
  • K Kuwabara
  • Y Hori
  • H Yaku
  • H Kaetsu
  • Y Takao
  • R Goto
  • M Hasegawa

Detail Information

Publications19

  1. pmc The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice
    Hiroyuki Miyazaki
    Division of Anesthesiology and Perioperative Medicine, Kobe University Graduate School of Medicine, Chuo Ku, Kobe, Hyogo, 650 0017, Japan
    BMC Nephrol 13:153. 2012
    ..In this study, we tested whether T-5224 has a potential inhibitory effect against LPS-induced AKI, by suppressing the TNF-alpha inflammatory response and other downstream effectors...
  2. ncbi request reprint Oral clonidine premedication reduces minimum alveolar concentration of sevoflurane for tracheal intubation in children
    K Nishina
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesthesiology 87:1324-7. 1997
    ..The minimum alveolar concentration for tracheal intubation (MAC(TI)) of sevoflurane was assessed with and without N2O and clonidine premedication...
  3. ncbi request reprint Effects of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion in children
    K Nishina
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesthesiology 88:922-7. 1998
    ..The effect of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion were investigated in children undergoing minor surgery...
  4. ncbi request reprint The effects of clonidine and dexmedetomidine on human neutrophil functions
    K Nishina
    Department of Anaesthesiology and Intensive Care Medicine, Kobe University School of Medicine, Japan
    Anesth Analg 88:452-8. 1999
    ..These findings indicate that it may not be necessary to take special care in using alpha2-agonists in patients with infection, sepsis, or systemic inflammation...
  5. ncbi request reprint Propofol attenuates diaphragmatic dysfunction induced by septic peritonitis in hamsters
    K Mikawa
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesthesiology 94:652-60. 2001
    ..Propofol scavenges this reactive molecule. The authors conducted the current study to evaluate whether propofol prevents diaphragmatic dysfunction induced by septic peritonitis...
  6. ncbi request reprint ONO1714, a new inducible nitric oxide synthase inhibitor, attenuates sepsis-induced diaphragmatic dysfunction in hamsters
    K Nishina
    Departments of Anaesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kobe, Japan
    Anesth Analg 92:959-66. 2001
    ..Pretreatment with ONO1714, a new selective inducible nitric oxide synthase inhibitor, attenuated sepsis-induced diaphragmatic dysfunction in hamsters...
  7. ncbi request reprint Attenuation of the cardiovascular and catecholamine responses to tracheal intubation with oral guanabenz
    K Mikawa
    Department of Anaesthesiology, Kobe University School of Medicine, Japan
    Anesth Analg 76:585-91. 1993
    ....
  8. ncbi request reprint Oral clonidine premedication does not change efficacy of simulated epidural test dose in sevoflurane-anesthetized children
    M Shiga
    Department of Anesthesiology, Kobe Children s Hospital, Kobe, Japan
    Anesthesiology 93:954-8. 2000
    ..These data suggest that oral clonidine premedication does not alter the efficacy of a simulated epidural test dose containing epinephrine or isoproterenol...
  9. ncbi request reprint The effect of halothane and sevoflurane on fatigue-induced changes in hamster diaphragmatic contractility
    T Kagawa
    Department of Anesthesiology, Kobe University School of Medicine, Japan
    Anesth Analg 86:392-7. 1998
    ..Our findings suggest that increased load on the diaphragm during volatile anesthesia may lead to impaired diaphragmatic contractility...
  10. ncbi request reprint Clonidine decreases the dose of thiamylal required to induce anesthesia in children
    K Nishina
    Department of Anaesthesiology, Kobe University School of Medicine, Japan
    Anesth Analg 79:766-8. 1994
    ..05). Premedication with oral clonidine reduced the dose of intravenous thiamylal required for the induction of anesthesia in children...
  11. ncbi request reprint A comparison of atenolol, labetalol, esmolol, and landiolol for altering human neutrophil functions
    K Nishina
    Department of Anesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kobe, Japan
    Anesth Analg 93:641-4. 2001
    ..Atenolol, labetalol, esmolol, and landiolol at clinically relevant concentrations failed to change neutrophil functions. Our findings indicate that we may be able to use these beta-antagonists without great caution in clinical settings...
  12. ncbi request reprint The effects of lidocaine on nitric oxide production from an activated murine macrophage cell line
    M Shiga
    Department of Anesthesiology, Kobe University School of Medicine, Kobe, Japan
    Anesth Analg 92:128-33. 2001
    ..The attenuating effect of lidocaine on organ injuries previously reported may be explained by the ability of the drug to suppress this inflammatory mediator...
  13. ncbi request reprint Crucial role of group IIA phospholipase A(2) in oleic acid-induced acute lung injury in rabbits
    S Furue
    Department of Anesthesiology, Kobe University School of Medicine, Kobe, Japan
    Am J Respir Crit Care Med 160:1292-302. 1999
    ..Thus, sPLA(2) appears to play a key role in OA-induced lung injury, suggesting that the group IIA PLA(2) inhibitor may be a promising agent for patients with acute respiratory distress syndrome (ARDS)...
  14. ncbi request reprint ONO-1714, a new inducible nitric oxide synthase inhibitor, attenuates diaphragmatic dysfunction associated with cerulein-induced pancreatitis in rats
    K Mikawa
    Departments of Anaesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kusunoki-cho 7, Chuo-ku, Kobe 650-0017, Japan
    Crit Care Med 29:1215-21. 2001
    ..This beneficial effect of ONO-1714 may be attributable, in part, to inhibition of diaphragmatic lipid peroxidation induced by nitric oxide-derived free radicals...
  15. ncbi request reprint Effects of ropivacaine on human neutrophil function: comparison with bupivacaine and lidocaine
    K Mikawa
    Kobe University Graduate School of Medicine, Department of Anesthesia and Perioperative Medicine, Faculty of Medical Sciences, Kobe, Japan
    Eur J Anaesthesiol 20:104-10. 2003
    ..However, many local anaesthetics impair certain neutrophil functions. The aim was to assess the effects of ropivacaine, bupivacaine and lidocaine on human neutrophils from adult volunteers...
  16. ncbi request reprint Effects of edaravone on human neutrophil function
    K Mikawa
    Department of Anesthesia and Perioperative Medicine, Faculty of Medical Sciences, Kobe University Graduate School of Medicine, Kobe 650 0017, Japan
    Acta Anaesthesiol Scand 49:385-9. 2005
    ..The aim of the current study was to assess the effect of edaravone, a novel free-radical scavenger, on several aspects of human neutrophil function using an in vitro system...
  17. ncbi request reprint Naloxone scavenges reactive oxygen species
    K Mikawa
    Acta Anaesthesiol Scand 50:1171-3. 2006
  18. ncbi request reprint Lidocaine attenuates streptozotocin-induced diaphragmatic dysfunction in rats
    S I Kodama
    Acta Anaesthesiol Scand 48:1066-7. 2004
  19. ncbi request reprint The effects of pentazocine, buprenorphine and butorphanol on human neutrophil functions
    K Mikawa
    Acta Anaesthesiol Scand 50:643-4. 2006