Research Topics
| K NishinaSummaryAffiliation: Kobe University Country: Japan Publications
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Detail Information
Publications
Oral clonidine premedication reduces minimum alveolar concentration of sevoflurane for tracheal intubation in childrenK Nishina
Department of Anesthesiology, Kobe University School of Medicine, Japan
Anesthesiology 87:1324-7. 1997..The minimum alveolar concentration for tracheal intubation (MAC(TI)) of sevoflurane was assessed with and without N2O and clonidine premedication...
Effects of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion in childrenK Nishina
Department of Anesthesiology, Kobe University School of Medicine, Japan
Anesthesiology 88:922-7. 1998..The effect of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion were investigated in children undergoing minor surgery...
The effects of clonidine and dexmedetomidine on human neutrophil functionsK Nishina
Department of Anaesthesiology and Intensive Care Medicine, Kobe University School of Medicine, Japan
Anesth Analg 88:452-8. 1999..These findings indicate that it may not be necessary to take special care in using alpha2-agonists in patients with infection, sepsis, or systemic inflammation...
ONO1714, a new inducible nitric oxide synthase inhibitor, attenuates sepsis-induced diaphragmatic dysfunction in hamstersK Nishina
Departments of Anaesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kobe, Japan
Anesth Analg 92:959-66. 2001..Pretreatment with ONO1714, a new selective inducible nitric oxide synthase inhibitor, attenuated sepsis-induced diaphragmatic dysfunction in hamsters...
Attenuation of the cardiovascular and catecholamine responses to tracheal intubation with oral guanabenzK Mikawa
Department of Anaesthesiology, Kobe University School of Medicine, Japan
Anesth Analg 76:585-91. 1993....
Propofol attenuates diaphragmatic dysfunction induced by septic peritonitis in hamstersK Mikawa
Department of Anesthesiology, Kobe University School of Medicine, Japan
Anesthesiology 94:652-60. 2001..Propofol scavenges this reactive molecule. The authors conducted the current study to evaluate whether propofol prevents diaphragmatic dysfunction induced by septic peritonitis...
The effect of halothane and sevoflurane on fatigue-induced changes in hamster diaphragmatic contractilityT Kagawa
Department of Anesthesiology, Kobe University School of Medicine, Japan
Anesth Analg 86:392-7. 1998..Our findings suggest that increased load on the diaphragm during volatile anesthesia may lead to impaired diaphragmatic contractility...
Oral clonidine premedication does not change efficacy of simulated epidural test dose in sevoflurane-anesthetized childrenM Shiga
Department of Anesthesiology, Kobe Children s Hospital, Kobe, Japan
Anesthesiology 93:954-8. 2000..These data suggest that oral clonidine premedication does not alter the efficacy of a simulated epidural test dose containing epinephrine or isoproterenol...
Clonidine decreases the dose of thiamylal required to induce anesthesia in childrenK Nishina
Department of Anaesthesiology, Kobe University School of Medicine, Japan
Anesth Analg 79:766-8. 1994..05). Premedication with oral clonidine reduced the dose of intravenous thiamylal required for the induction of anesthesia in children...
The effects of lidocaine on nitric oxide production from an activated murine macrophage cell lineM Shiga
Department of Anesthesiology, Kobe University School of Medicine, Kobe, Japan
Anesth Analg 92:128-33. 2001..The attenuating effect of lidocaine on organ injuries previously reported may be explained by the ability of the drug to suppress this inflammatory mediator...
A comparison of atenolol, labetalol, esmolol, and landiolol for altering human neutrophil functionsK Nishina
Department of Anesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kobe, Japan
Anesth Analg 93:641-4. 2001..Atenolol, labetalol, esmolol, and landiolol at clinically relevant concentrations failed to change neutrophil functions. Our findings indicate that we may be able to use these beta-antagonists without great caution in clinical settings...
Crucial role of group IIA phospholipase A(2) in oleic acid-induced acute lung injury in rabbitsS Furue
Department of Anesthesiology, Kobe University School of Medicine, Kobe, Japan
Am J Respir Crit Care Med 160:1292-302. 1999..Thus, sPLA(2) appears to play a key role in OA-induced lung injury, suggesting that the group IIA PLA(2) inhibitor may be a promising agent for patients with acute respiratory distress syndrome (ARDS)...
ONO-1714, a new inducible nitric oxide synthase inhibitor, attenuates diaphragmatic dysfunction associated with cerulein-induced pancreatitis in ratsK Mikawa
Departments of Anaesthesiology and Intensive Care Unit, Kobe University School of Medicine, Kusunoki-cho 7, Chuo-ku, Kobe 650-0017, Japan
Crit Care Med 29:1215-21. 2001..This beneficial effect of ONO-1714 may be attributable, in part, to inhibition of diaphragmatic lipid peroxidation induced by nitric oxide-derived free radicals...
Effects of ropivacaine on human neutrophil function: comparison with bupivacaine and lidocaineK Mikawa
Kobe University Graduate School of Medicine, Department of Anesthesia and Perioperative Medicine, Faculty of Medical Sciences, Kobe, Japan
Eur J Anaesthesiol 20:104-10. 2003..However, many local anaesthetics impair certain neutrophil functions. The aim was to assess the effects of ropivacaine, bupivacaine and lidocaine on human neutrophils from adult volunteers...
Effects of edaravone on human neutrophil functionK Mikawa
Department of Anesthesia and Perioperative Medicine, Faculty of Medical Sciences, Kobe University Graduate School of Medicine, Kobe 650 0017, Japan
Acta Anaesthesiol Scand 49:385-9. 2005..The aim of the current study was to assess the effect of edaravone, a novel free-radical scavenger, on several aspects of human neutrophil function using an in vitro system...
Naloxone scavenges reactive oxygen speciesK Mikawa
Acta Anaesthesiol Scand 50:1171-3. 2006
Lidocaine attenuates streptozotocin-induced diaphragmatic dysfunction in ratsS-I Kodama
Acta Anaesthesiol Scand 48:1066-7. 2004
The effects of pentazocine, buprenorphine and butorphanol on human neutrophil functionsK Mikawa
Acta Anaesthesiol Scand 50:643-4. 2006
