Shuji Kitagawa

Summary

Affiliation: Kobe Pharmaceutical University
Country: Japan

Publications

  1. ncbi request reprint Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
    Tomohiro Nabekura
    Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
    Biochem Biophys Res Commun 327:866-70. 2005
  2. ncbi request reprint Efficient topical delivery of chlorogenic acid by an oil-in-water microemulsion to protect skin against UV-induced damage
    Shuji Kitagawa
    Kobe Pharmaceutical University, 4 19 1 Motoyamakita machi, Higashinada ku, Kobe, Japan
    Chem Pharm Bull (Tokyo) 59:793-6. 2011
  3. ncbi request reprint Enhanced skin delivery of genistein and other two isoflavones by microemulsion and prevention against UV irradiation-induced erythema formation
    Shuji Kitagawa
    Kobe Pharmaceutical University, Kobe 658 8558, Japan
    Chem Pharm Bull (Tokyo) 58:398-401. 2010
  4. doi request reprint Enhanced skin delivery of quercetin by microemulsion
    Shuji Kitagawa
    Kobe Pharmaceutical University, Kobe, Japan
    J Pharm Pharmacol 61:855-60. 2009
  5. ncbi request reprint Inhibition of P-glycoprotein function by tannic acid and pentagalloylglucose
    Shuji Kitagawa
    Kobe Pharmaceutical University, Motoyamakita machi 4 19 1, Kobe 658 8558, Japan
    J Pharm Pharmacol 59:965-9. 2007
  6. ncbi request reprint Physicochemical properties of tamoxifen hemicitrate sesquihydrate
    Takashi Kojima
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashinada, Kobe 658 8558, Japan
    Int J Pharm 352:146-51. 2008
  7. ncbi request reprint Distribution of polyphenols and a surfactant component in skin during Aerosol OT microemulsion-enhanced intradermal delivery
    Reiko Yutani
    Kobe Pharmaceutical University, 4 19 1 Motoyamakita machi, Kobe 658 8558, Japan
    Chem Pharm Bull (Tokyo) 60:989-94. 2012
  8. ncbi request reprint Physicochemical characterization of tamoxifen citrate pseudopolymorphs, methanolate and ethanolate
    Takashi Kojima
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashi Nada, Kobe, Japan
    Chem Pharm Bull (Tokyo) 55:407-11. 2007
  9. ncbi request reprint Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells
    Shuji Kitagawa
    Kobe Pharmaceutical University, Kobe, Japan
    Biol Pharm Bull 30:1979-81. 2007
  10. ncbi request reprint Effect of pharmaceutical excipients on the stability of trichlormethiazide tablets under humid conditions
    Reiko Teraoka
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Motoyama Kitamachi, Higashi Nada, Japan
    Chem Pharm Bull (Tokyo) 57:1343-7. 2009

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
    Tomohiro Nabekura
    Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
    Biochem Biophys Res Commun 327:866-70. 2005
    ..These results suggest that dietary phytochemicals, such as capsaicin, curcumin, [6]-gingerol, and resveratrol, have inhibitory effects on P-glycoprotein and potencies to cause drug-food interactions...
  2. ncbi request reprint Efficient topical delivery of chlorogenic acid by an oil-in-water microemulsion to protect skin against UV-induced damage
    Shuji Kitagawa
    Kobe Pharmaceutical University, 4 19 1 Motoyamakita machi, Higashinada ku, Kobe, Japan
    Chem Pharm Bull (Tokyo) 59:793-6. 2011
    ..These findings indicate the potential use of hydrophilic chlorogenic acid with o/w-type microemulsion as a vehicle to protect skin against UV-induced oxidative damage...
  3. ncbi request reprint Enhanced skin delivery of genistein and other two isoflavones by microemulsion and prevention against UV irradiation-induced erythema formation
    Shuji Kitagawa
    Kobe Pharmaceutical University, Kobe 658 8558, Japan
    Chem Pharm Bull (Tokyo) 58:398-401. 2010
    ..These findings indicate the potential use of w/o-type microemulsion for the delivery of genistein to protect skin against UV-induced oxidative damage...
  4. doi request reprint Enhanced skin delivery of quercetin by microemulsion
    Shuji Kitagawa
    Kobe Pharmaceutical University, Kobe, Japan
    J Pharm Pharmacol 61:855-60. 2009
    ..The aim of this study was to determine the usefulness of a microemulsion for that purpose...
  5. ncbi request reprint Inhibition of P-glycoprotein function by tannic acid and pentagalloylglucose
    Shuji Kitagawa
    Kobe Pharmaceutical University, Motoyamakita machi 4 19 1, Kobe 658 8558, Japan
    J Pharm Pharmacol 59:965-9. 2007
    ..The findings also suggested that the presence of a large number of galloyl groups in polyphenols strengthens the interaction with regulatory regions in P-gp...
  6. ncbi request reprint Physicochemical properties of tamoxifen hemicitrate sesquihydrate
    Takashi Kojima
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashinada, Kobe 658 8558, Japan
    Int J Pharm 352:146-51. 2008
    ....
  7. ncbi request reprint Distribution of polyphenols and a surfactant component in skin during Aerosol OT microemulsion-enhanced intradermal delivery
    Reiko Yutani
    Kobe Pharmaceutical University, 4 19 1 Motoyamakita machi, Kobe 658 8558, Japan
    Chem Pharm Bull (Tokyo) 60:989-94. 2012
    ....
  8. ncbi request reprint Physicochemical characterization of tamoxifen citrate pseudopolymorphs, methanolate and ethanolate
    Takashi Kojima
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashi Nada, Kobe, Japan
    Chem Pharm Bull (Tokyo) 55:407-11. 2007
    ....
  9. ncbi request reprint Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells
    Shuji Kitagawa
    Kobe Pharmaceutical University, Kobe, Japan
    Biol Pharm Bull 30:1979-81. 2007
    ..Analysis of verapamil-stimulated ATPase activity in membrane vesicles expressing human P-gp suggested that the increased daunorubicin accumulation by M4 was at least partly due to ATPase inhibition of P-gp...
  10. ncbi request reprint Effect of pharmaceutical excipients on the stability of trichlormethiazide tablets under humid conditions
    Reiko Teraoka
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Motoyama Kitamachi, Higashi Nada, Japan
    Chem Pharm Bull (Tokyo) 57:1343-7. 2009
    ..It was found that the TCM content decreased significantly in a binary mixture of TCM/HPC 1 : 1...
  11. doi request reprint Effects of phosphatidylethanolamine N-methyltransferase on phospholipid composition, microvillus formation and bile salt resistance in LLC-PK1 cells
    Shin ya Morita
    Department of Pharmacy, Shiga University of Medical Science Hospital, Otsu City, Shiga, Japan
    FEBS J 278:4768-81. 2011
    ..Because most bile salts exist as conjugated forms in the bile canaliculi, PEMT may be important in the protection of hepatocytes from bile salts and in cholestatic liver injury...
  12. doi request reprint Presence of apolipoprotein C-III attenuates apolipoprotein E-mediated cellular uptake of cholesterol-containing lipid particles by HepG2 cells
    Shin ya Morita
    Kobe Pharmaceutical University, Higashinada ku, Kobe, Japan
    Lipids 46:323-32. 2011
    ..Furthermore, cholesterol may affect these functions of apoC-III and apoE involved in the clearance of lipoprotein remnants...
  13. ncbi request reprint Functional analysis of two isoforms of phosphatidylethanolamine N-methyltransferase
    Shin ya Morita
    Kobe Pharmaceutical University, Higashinada ku, Kobe 658 8558, Japan
    Biochem J 432:387-98. 2010
    ..Based upon these findings, we propose a model in which the enzymatic activity and substrate specificity are regulated by the glycosylated N-terminal region of PEMT-L localized in the ER lumen...
  14. ncbi request reprint Effect of spectroscopic properties on photostability of tamoxifen citrate polymorphs
    Takashi Kojima
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashi Nada, Kobe 658 8558, Japan
    Int J Pharm 336:346-51. 2007
    ..The results obtained suggested that the photodegradation followed by surface color change of form A crystal was caused by the selective absorption of photoenergy of UVA light irradiated by a xenon lamp...
  15. pmc Enzymatic measurement of phosphatidic acid in cultured cells
    Shin ya Morita
    Laboratory of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashinada ku, Kobe 658 8558, Japan
    J Lipid Res 50:1945-52. 2009
    ..This novel method for PA quantification is simple, rapid, specific, sensitive, and high-throughput and will help to study the biological functions of PA and its related enzymes...
  16. ncbi request reprint Inhibition of P-glycoprotein function by tea catechins in KB-C2 cells
    Shuji Kitagawa
    Niigata University of Pharmacy and Applied Life Sciences, Kamishin ei cho 5 13 2, 950 2081, Japan
    J Pharm Pharmacol 56:1001-5. 2004
    ....
  17. ncbi request reprint Effects of alkyl gallates on P-glycoprotein function
    Shuji Kitagawa
    Laboratory of Pharmaceutics, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Japan
    Biochem Pharmacol 70:1262-6. 2005
    ..The cytotoxicity of daunorubicin was recovered in the presence of alkyl gallates possibly due to their inhibition of P-gp function...
  18. ncbi request reprint Structure-activity relationships of the inhibitory effects of flavonoids on P-glycoprotein-mediated transport in KB-C2 cells
    Shuji Kitagawa
    Niigata University of Pharmacy and Applied Life Sciences, Japan
    Biol Pharm Bull 28:2274-8. 2005
    ..These results suggested that hydrophobicity as well as planar structure is important for the inhibitory effects of flavonoids on P-gp-mediated transport...
  19. doi request reprint Effects of plant sterols on human multidrug transporters ABCB1 and ABCC1
    Tomohiro Nabekura
    Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Higashi jima, Akiha ku, Niigata 956 8603, Japan
    Biochem Biophys Res Commun 369:363-8. 2008
    ..These results suggest that guggulsterone, a natural dietary hypolipidemic agent have dual inhibitory effects on P-gp and MRP1 and the potencies to cause food-drug interactions...
  20. ncbi request reprint Effect of triterpenoids isolated from the floral spikes of Betula platyphylla var. japonica on P-glycoprotein function
    Michiko Sekiya
    Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
    Planta Med 73:1558-62. 2007
    ..In addition, compounds 13 and 20 showed a weak inhibitory activity of P-gp ATPase. These results suggested that MDR reversing effects of compounds 13 and 20 are partly involved in inhibition of P-gp ATPase...
  21. ncbi request reprint Triterpenoids from the floral spikes of Betula platyphylla var. japonica and their reversing activity against multidrug-resistant cancer cells
    Yoshiki Kashiwada
    Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi 1 78, Tokushima 770 8505, Japan
    J Nat Prod 70:623-7. 2007
    ..Compound 10 reversed the cytotoxicity of colchicine against KB-C2 cells at 8.1 microM and showed comparable potency to 5 microM verapamil...