Shinichi Sakuramoto

Summary

Affiliation: Kitasato University
Country: Japan

Publications

  1. ncbi Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    N Engl J Med 357:1810-20. 2007
  2. ncbi Laparoscopy-assisted pancreas- and spleen-preserving total gastrectomy for gastric cancer as compared with open total gastrectomy
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa, 228 8520, Japan
    Surg Endosc 23:2416-23. 2009
  3. ncbi Technique of esophagojejunostomy using transoral placement of the pretilted anvil head after laparoscopic gastrectomy for gastric cancer
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa 228 8520, Japan
    Surgery 147:742-7. 2010
  4. ncbi Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa, 228 8520, Japan
    Surg Endosc 27:1695-705. 2013
  5. ncbi Lymphatic tumor emboli detected by D2-40 immunostaining can more accurately predict lymph-node metastasis
    Hiromitsu Moriya
    Department of Surgery, School of Medicine, Kitasato University, Tokyo, Japan
    World J Surg 35:2031-7. 2011
  6. ncbi Which patients with advanced, proximal gastric cancer benefit from complete clearance of spleno-pancreatic lymph nodes?
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1, Kitasato, Sagamihara shi, Kanagawa 228, Japan
    Anticancer Res 22:3513-7. 2002
  7. ncbi Five-year outcomes of a randomized phase III trial comparing adjuvant chemotherapy with S-1 versus surgery alone in stage II or III gastric cancer
    Mitsuru Sasako
    Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo, 663 8501, Japan
    J Clin Oncol 29:4387-93. 2011
  8. ncbi Clinical experience of laparoscopy-assisted proximal gastrectomy with Toupet-like partial fundoplication in early gastric cancer for preventing reflux esophagitis
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa, Japan
    J Am Coll Surg 209:344-51. 2009
  9. ncbi Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer
    Akira Ooki
    Department of Surgery, Kitasato University Hospital, Kitasato 1 15 1, Sagamihara 228 8555, Kanagawa, Japan
    BMC Cancer 11:122. 2011
  10. ncbi Clinical significance of total gastrectomy for proximal gastric cancer
    Akira Ooki
    Department of Surgery, Kitasato University Hospital, Kitasato 1 15 1, Sagamihara 228 8555, Kanagawa, Japan
    Anticancer Res 28:2875-83. 2008

Collaborators

Detail Information

Publications34

  1. ncbi Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    N Engl J Med 357:1810-20. 2007
    ..Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer...
  2. ncbi Laparoscopy-assisted pancreas- and spleen-preserving total gastrectomy for gastric cancer as compared with open total gastrectomy
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa, 228 8520, Japan
    Surg Endosc 23:2416-23. 2009
    ..To assess the safety and usefulness of LATG, we compared the outcomes of LATG with those of open total gastrectomy (OTG)...
  3. ncbi Technique of esophagojejunostomy using transoral placement of the pretilted anvil head after laparoscopic gastrectomy for gastric cancer
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa 228 8520, Japan
    Surgery 147:742-7. 2010
    ..The authors report on a method modified for laparoscopy-assisted, esophagojejunostomy performed by placing the pretilted anvil head via the transoral approach...
  4. ncbi Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa, 228 8520, Japan
    Surg Endosc 27:1695-705. 2013
    ..The purpose of this study was to compare laparoscopic versus ODG with respect to specific primary and secondary short-term outcomes...
  5. ncbi Lymphatic tumor emboli detected by D2-40 immunostaining can more accurately predict lymph-node metastasis
    Hiromitsu Moriya
    Department of Surgery, School of Medicine, Kitasato University, Tokyo, Japan
    World J Surg 35:2031-7. 2011
    ..This present study was designed to determine the accuracy of LY grade for predicting the risk of N...
  6. ncbi Which patients with advanced, proximal gastric cancer benefit from complete clearance of spleno-pancreatic lymph nodes?
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1, Kitasato, Sagamihara shi, Kanagawa 228, Japan
    Anticancer Res 22:3513-7. 2002
    ..The prognostic significance of dissecting spleno-pancreatic nodes remains unclear in patients with advanced proximal gastric cancer...
  7. ncbi Five-year outcomes of a randomized phase III trial comparing adjuvant chemotherapy with S-1 versus surgery alone in stage II or III gastric cancer
    Mitsuru Sasako
    Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo, 663 8501, Japan
    J Clin Oncol 29:4387-93. 2011
    ..The results were therefore opened at the recommendation of an independent data and safety monitoring committee. We report 5-year follow-up data on patients enrolled onto the ACTS-GC study...
  8. ncbi Clinical experience of laparoscopy-assisted proximal gastrectomy with Toupet-like partial fundoplication in early gastric cancer for preventing reflux esophagitis
    Shinichi Sakuramoto
    Department of Surgery, Kitasato University School of Medicine, 2 1 1 Asamizodai, Sagamihara, Kanagawa, Japan
    J Am Coll Surg 209:344-51. 2009
    ..Clinical outcomes are described here in patients with reconstruction by esophagogastrostomy with Toupet-like partial fundoplication (TPF) in LAPG...
  9. ncbi Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer
    Akira Ooki
    Department of Surgery, Kitasato University Hospital, Kitasato 1 15 1, Sagamihara 228 8555, Kanagawa, Japan
    BMC Cancer 11:122. 2011
    ..In the present study, we examined the mechanisms regulating PRL-3 expression, and assessed the clinical potential of PRL-3-targeted therapy in gastric cancer...
  10. ncbi Clinical significance of total gastrectomy for proximal gastric cancer
    Akira Ooki
    Department of Surgery, Kitasato University Hospital, Kitasato 1 15 1, Sagamihara 228 8555, Kanagawa, Japan
    Anticancer Res 28:2875-83. 2008
    ..The principal difference between total gastrectomy (TG) and proximal gastrectomy (PG) is whether lymph node (LN) 4d is dissected by radical lymphadenectomy...
  11. ncbi Pre-operative tumor assessment of patients with gastric cancer based on virtual endoscopy using multidetector-row computer tomography
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1 Kitasato, Sagamihara shi, Japan
    Anticancer Res 26:4641-5. 2006
    ..The aim of the present study was to evaluate the pre-operative assessment of gastric cancer tumors using 32-multidetector row-CT...
  12. ncbi Phosphatase of regenerating liver-3 as a prognostic biomarker in histologically node-negative gastric cancer
    Akira Ooki
    Department of Surgery, Kitasato University Hospital, Sagamihara 228 8555, Kanagawa, Japan
    Oncol Rep 21:1467-75. 2009
    ..We propose that PRL-3 expression can have a clinical potential as a prognostic biomarker that may facilitate the development of adjuvant chemotherapy for advanced gastric cancer with stage I disease...
  13. ncbi Phosphatase of regenerating liver-3 as a convergent therapeutic target for lymph node metastasis in esophageal squamous cell carcinoma
    Akira Ooki
    Department of Surgery, Kitasato University Hospital, Sagamihara, Kanagawa, Japan
    Int J Cancer 127:543-54. 2010
    ..Moreover, the expression status may be a landmark to select patients with benefit from PRL-3-targeted therapy. Thus, PRL-3 could be a convergent therapeutic target against ESCC with LNM...
  14. ncbi Transfusion alert for patients with curable cancer
    Keishi Yamashita
    Department of Surgery, Kitasato University Hospital, Kanagawa, Japan
    World J Surg 31:2315-22. 2007
    ..However, the prognostic independence among related factors and clinical significance of the interaction remains elusive...
  15. ncbi Lymph node metastasis density (ND)-factor association with malignant degree and ND40 as "non-curative factor" in gastric cancer
    Keishi Yamashita
    Department of Surgery, Kitasato University Hospital, Kitasato 1 15 1, Sagamihara 228 8555, Kanagawa, Japan
    Anticancer Res 28:435-41. 2008
    ..A search for the molecules associated with higher ND value within an identical stage could lead to objective determination of the degree of malignancy and development of novel strategies against advanced gastric cancer...
  16. ncbi Comparison of staging between the old (6th edition) and new (7th edition) TNM classifications in advanced gastric cancer
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1, Kitasato, Minami Ku, Sagamihara, Kanagawa 252 0374, Japan
    Anticancer Res 31:2361-5. 2011
    ....
  17. ncbi Laparoscopy-assisted distal gastrectomy for early gastric cancer with complete situs inversus: report of a case
    Nobue Futawatari
    Department of Surgery, School of Medicine, Kitasato University, 2 1 1 Asamizodai, Sagamihara, Kanagawa, 228 8520, Japan
    Surg Today 40:64-7. 2010
    ..Based on a histopathological examination, a 5.0 x 5.0-cm, mucosal, poorly differentiated adenocarcinoma (pT1, pN0, sH0, sP0, sM0, Stage IA) was diagnosed...
  18. ncbi Strong association of lymph node metastasis with intraperitoneal free cancer cell (IFCC) in advanced gastric cancer
    Keishi Yamashita
    Department of Surgery, Kitasato University Higashi Hospital, Kanagawa, Japan
    Hepatogastroenterology 55:1873-7. 2008
    ..Advanced gastric cancer is a disease with dismal prognosis, which is mainly characterized by the emerging intraperitoneal free gastric cancer cells (IFCC). Our interest is to elucidate a causative phenotype linking to IFCC...
  19. ncbi A new diagnostic method for early gastric cancer: volume measurement by 3-dimensional endoscopic ultrasonography in early gastric cancer and its clinical significance
    Nobue Futawatari
    Department of Surgery, School of Medicine, Kitasato University, Sagamihara shi, Kanagawa 228, Japan
    Anticancer Res 28:2907-12. 2008
    ..The objective of the present study was to measure the volume of early gastric cancer using 3-dimensional endoscopic ultrasonography (3D-EUS) and to ascertain the clinical significance of this new diagnostic method...
  20. ncbi Survival after surgical treatment of early gastric cancer: surgical techniques and long-term survival
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1 Kitasato, Sagamihara shi, 228 Kanagawa, Japan
    Langenbecks Arch Surg 389:69-74. 2004
    ..Recent results from long-term follow-up of a large number of patients who have undergone gastric resection for early gastric cancer (EGC) have not yet been fully evaluated...
  21. ncbi First drainage lymph node(s) in gastric cancer: analysis of the topographical pattern of lymph node metastasis in patients with pN-1 stage tumors
    Shiro Kikuchi
    Department of Surgery, Kitasato University, School of Medicine, 1-15-1, Kitasato, Sagamihara-shi, Kanagawa 228, Japan
    Anticancer Res 23:601-4. 2003
    ..0001). CONCLUSION: Although perigastric lymph nodes are important first sites of drainage from pN-1 stage gastric tumors, the pattern of lymph node metastasis varies widely within a regional area even in pN-1 stage patients...
  22. ncbi Laparoscopic Heller myotomy with Toupet fundoplication for achalasia straightens the esophagus and relieves dysphagia
    Natsuya Katada
    Department of Surgery, School of Medicine, Kitasato University 2 1 1, Asamizodai, Sagamihara, Kanagawa 228 8520, Japan
    Am J Surg 192:1-8. 2006
    ..A standard procedure for the treatment of achalasia remains to be established. We assessed the usefulness of a laparoscopic Heller myotomy with a Toupet fundoplication (LHT)...
  23. ncbi Role of endoscopic clipping for determining the resection line for tumors located in the middle or upper corpus of the stomach: experience with 100 gastrectomies for early gastric cancer
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1, Kitasato, Sagamihara shi, 228 8555 Kanagawa, Japan
    Anticancer Res 24:4163-8. 2004
    ..The efficacy and limitations of preoperative endoscopic clipping for determining the resection line in patients with early gastric cancer remain unclear...
  24. ncbi Trend in gastric cancer: 35 years of surgical experience in Japan
    Keishi Yamashita
    Department of Surgery, Kitasato University School of Medicine, Kitasato 1 15 1, Minami Ku, Sagamihara, Kanagawa 252 0374, Japan
    World J Gastroenterol 17:3390-7. 2011
    ..To investigate the trend in gastric cancer surgery in the context of rapid therapeutic advancement in Japan and East Asia...
  25. ncbi Evaluation of prognostic factors for the response to S-1 in patients with stage II or III advanced gastric cancer who underwent gastrectomy
    Kenji Ishido
    Department of Gastroenterology, Kitasato University East Hospital, 2 1 1 Asamizodai, Sagamihara, Kanagawa, Japan
    Pharmacogenet Genomics 19:955-64. 2009
    ..However, the role of gene expression profile of patients who received postoperative adjuvant chemotherapy remains unclear. In this study, we evaluated how TS and other associated genes related to outcome...
  26. ncbi Validation of staging systems for gastric cancer
    Keishi Yamashita
    Department of Surgery, Kitasato University Hospital, 1 15 1 Kitastato, Sagamihara, Kanagawa 228 8555, Japan
    Gastric Cancer 11:111-8. 2008
    ..This study aimed to validate and improve upon the current versions for a better prognostic stratification of gastric cancer...
  27. ncbi Lymph node metastasis density and growth pattern as independent prognostic factors in advanced esophageal squamous cell carcinoma
    Akira Ooki
    Department of Surgery, Kitasato University Higashi Hospital, Asamizodai 2 1 1, Sagamihara 228 8520 Kanagawa, Japan
    World J Surg 31:2184-91. 2007
    ..Thus staging could be expanded to make the prognosis a valuable clinical tool, and to improve knowledge of the biological traits of advanced ESCC...
  28. ncbi Recent trends in the management of achalasia
    Natsuya Katada
    Department of Surgery, School of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan
    Ann Thorac Cardiovasc Surg 18:420-8. 2012
    ..Definitive conclusions regarding the benefits and risks of currently available treatments for achalasia must await the accumulation of evidence from well-designed clinical trials...
  29. ncbi New technique for purse string suture in stapled esophagojejunostomy using a new "needle cap" device
    Shiro Kikuchi
    Department of Surgery, Kitasato University East Hospital, Kanagawa, Japan
    Hepatogastroenterology 53:155-6. 2006
    ..We present herein a new technique for purse string suture in stapled esophagojejunostomy using this device...
  30. ncbi Efficacy of endoscopic surveillance of the upper gastrointestinal tract following distal gastrectomy for early gastric cancer
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1-15-1, Kitasato, Sagamihara-shi, Kanagawa 228, Japan
    Hepatogastroenterology 50:1704-7. 2003
    ....
  31. ncbi Clinical evaluation of pN-stage (TNM) in gastric cancer: an analysis of distribution of regional lymph nodes in node-positive patients
    Shiro Kikuchi
    Department of Surgery, Kitasato University School of Medicine, Sagamihara-shi, Kanagawa, Japan
    Anticancer Res 22:1141-4. 2002
    ....
  32. ncbi New diagnostic imaging of gastointestinal tumors: a preliminary study of three-dimensional tumor structure and volumetry
    Shiro Kikuchi
    Department of Surgery, School of Medicine, Kitasato University, 1 15 1 Kitasato, Sagamihara shi, Kanagawa 228, Japan
    Anticancer Res 25:2935-41. 2005
    ....
  33. ncbi Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications
    Keishi Yamashita
    Department of Surgery, Kitasato University School of Medicine, 1 15 1 Kitasato, Minami Ku, Sagamihara, Kanagawa 252 0374, Japan
    Surg Today 41:24-38. 2011
    ..Such genes are potential targets for cancer treatment, and might also serve as biomarkers of gastric cancer for either the diagnosis or for determining the prognosis or the response to treatment...
  34. ncbi Newly emerging standard chemotherapies for gastric cancer and clinical potential in elderly patients
    Shinichi Sakuramoto
    Shinichi Sakuramoto, Keishi Yamashita, Masahiko Watanabe, Department of Surgery, Kitasato University Hospsital, Kitasato 1 15 1, Sagamihara, Kanagawa 228 8555, Japan
    World J Gastrointest Oncol 1:47-54. 2009
    ....