Kazuhiko Otoguro

Summary

Affiliation: Kitasato University
Country: Japan

Publications

  1. Otoguro K, Ishiyama A, Namatame M, Nishihara A, Furusawa T, Masuma R, et al. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008;61:372-8 pubmed publisher
    ..b. rhodesiense are presented. Cytotoxicity was determined using a human MRC-5 cell line. This is the first report of antitrypanosomal activities of the 10 microbial metabolites listed above. ..
  2. Otoguro K, Ishiyama A, Iwatsuki M, Namatame M, Nishihara Tukashima A, Kiyohara H, et al. In vitro antitrypanosomal activity of bis(bibenzyls)s and bibenzyls from liverworts against Trypanosoma brucei. J Nat Med. 2012;66:377-82 pubmed publisher
    ..Our finding represents the first report of the promising trypanocidal activity of these compounds. The research also provides valuable insight into structure-activity relationships and the possible mode of action of the compounds. ..
  3. Otoguro K, Iwatsuki M, Ishiyama A, Namatame M, Nishihara Tsukashima A, Kiyohara H, et al. In vitro antitrypanosomal activity of some phenolic compounds from propolis and lactones from Fijian Kawa (Piper methysticum). J Nat Med. 2012;66:558-61 pubmed publisher
    ..Our findings represent the first report of the promising trypanocidal activity of these compounds. ..
  4. Otoguro K, Iwatsuki M, Ishiyama A, Namatame M, Nishihara Tukashima A, Kiyohara H, et al. In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. Phytochemistry. 2011;72:2024-30 pubmed publisher
    ..Present results also provide some valuable insight with regard to structure-activity relationships and the possible mode of action of the compounds. ..

Detail Information

Publications4

  1. Otoguro K, Ishiyama A, Namatame M, Nishihara A, Furusawa T, Masuma R, et al. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008;61:372-8 pubmed publisher
    ..b. rhodesiense are presented. Cytotoxicity was determined using a human MRC-5 cell line. This is the first report of antitrypanosomal activities of the 10 microbial metabolites listed above. ..
  2. Otoguro K, Ishiyama A, Iwatsuki M, Namatame M, Nishihara Tukashima A, Kiyohara H, et al. In vitro antitrypanosomal activity of bis(bibenzyls)s and bibenzyls from liverworts against Trypanosoma brucei. J Nat Med. 2012;66:377-82 pubmed publisher
    ..Our finding represents the first report of the promising trypanocidal activity of these compounds. The research also provides valuable insight into structure-activity relationships and the possible mode of action of the compounds. ..
  3. Otoguro K, Iwatsuki M, Ishiyama A, Namatame M, Nishihara Tsukashima A, Kiyohara H, et al. In vitro antitrypanosomal activity of some phenolic compounds from propolis and lactones from Fijian Kawa (Piper methysticum). J Nat Med. 2012;66:558-61 pubmed publisher
    ..Our findings represent the first report of the promising trypanocidal activity of these compounds. ..
  4. Otoguro K, Iwatsuki M, Ishiyama A, Namatame M, Nishihara Tukashima A, Kiyohara H, et al. In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. Phytochemistry. 2011;72:2024-30 pubmed publisher
    ..Present results also provide some valuable insight with regard to structure-activity relationships and the possible mode of action of the compounds. ..