Research Topics
| Satoshi YoshidaSummaryAffiliation: Kirin Brewery Co Country: Japan Publications
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Detail Information
Publications
Identification and characterization of genes related to the production of organic acids in yeastSatoshi Yoshida
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, 1 13 5 Fukuura, Kanazawa Ku, Yokohama shi, Kanagawa 236 0004, Japan
J Biosci Bioeng 113:556-61. 2012..Taken together, these results suggest that the regulation of many organic acids might be simultaneously achieved by activation or inactivation of a single gene...
Schizosaccharomyces pombe stt3+ is a functional homologue of Saccharomyces cerevisiae STT3 which regulates oligosaccharyltransferase activityS Yoshida
Kirin Brewery Co Ltd, Central Laboratories for Key Technology, Kanagawa, Japan
Yeast 15:497-505. 1999..Like Itm1, Spstt3+ partially suppressed the temperature sensitivity of the stt3-1 mutation of S. cerevisiae, indicating that Spstt3+ is a functional and structural homologue of the ScSTT3 gene...
A novel mechanism regulates H(2) S and SO(2) production in Saccharomyces cerevisiaeSatoshi Yoshida
Central Laboratories for Frontier Technology, Kirin Holdings Co Ltd, 1 13 5, Fukuura Kanazawa ku, Yokohama shi, Kanagawa 236 0004, Japan
Yeast 28:109-21. 2011..These results suggest that the balance of methionine and cysteine biosynthesis is important for yeast cell growth. Thus, Skp2p is one of the key components regulating this balance and H(2) S/SO(2) production...
Development of bottom-fermenting saccharomyces strains that produce high SO2 levels, using integrated metabolome and transcriptome analysisSatoshi Yoshida
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, 1 13 5 Fukuura Kanazawa ku, Yokohama shi, Kanagawa 236 0004, Japan
Appl Environ Microbiol 74:2787-96. 2008..One promising mutant produced much higher levels of SO(2) than the parent but produced parental levels of H(2)S...
Identification and characterization of amidase- homologous AMI1 genes of bottom-fermenting yeastSatoshi Yoshida
Central Laboratories for Frontier Technology, Kirin Holdings Co Ltd, 1 13 5 Fukuura Kanazawa ku, Yokohama shi, Kanagawa 236 0004, Japan
Yeast 24:1075-84. 2007....
Identification of bottom-fermenting yeast genes expressed during lager beer fermentationSatoshi Yoshida
Central Laboratories for Frontier Technology, Kirin Brewery Co Ltd, Kanagawa, Japan
Yeast 24:599-606. 2007..Most of BFY genes have significant homology with the S. bayanus genome...
Characterization of staurosporine-sensitive mutants of Saccharomyces cerevisiae: vacuolar functions affect staurosporine sensitivityS Yoshida
Central Laboratories for Key Technology, Kirin Brewery Co Ltd, Japan
Mol Gen Genet 263:877-88. 2000....
Expression profiling of the bottom fermenting yeast Saccharomyces pastorianus orthologous genes using oligonucleotide microarraysToshiko Minato
Central Laboratories for Frontier Technology, Kirin Holdings Co Ltd, Yokohama shi, Kanagawa, Japan
Yeast 26:147-65. 2009..We conclude that the oligonucleotide microarray that we constructed is a powerful tool for the monitoring of gene expression of the orthologous genes of S. pastorianus...
Efficient production of L-lactic acid from xylose by a recombinant Candida utilis strainHideyuki Tamakawa
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, 1 13 5 Fukuura, Kanazawa Ku, Yokohama shi, Kanagawa 236 0004, Japan
J Biosci Bioeng 113:73-5. 2012..The recombinant strain showed 53% increased L-lactic acid production compared with the reference strain expressing native XR (NADPH-preferring)...
Genetic engineering of Candida utilis yeast for efficient production of L-lactic acidShigehito Ikushima
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, Yokohama, Kanagawa, Japan
Biosci Biotechnol Biochem 73:1818-24. 2009..3 g/l of L-lactic acid from 108.7 g/l of glucose in 33 h, representing a 95.1% conversion. The maximum production rate of L-lactic acid was 4.9 g/l/h. The optical purity of the L-lactic acid was found to be more than 99.9% e.e...
Sugar induces death of the bottom fermenting yeast Saccharomyces pastorianusHiroyuki Yoshimoto
Central Laboratories for Frontier Technology, Kirin Holdings Company, Limited, Yokohama shi, Kanagawa 236 0004, Japan
J Biosci Bioeng 108:60-2. 2009..Fermentation tests using different ratios of glucose and non-glucose nutrients demonstrated that SICD is influenced by the balance between these nutrients...
Novel method to reduce fishy aftertaste in wine and seafood pairing using alcohol-treated yeast cellsToshikazu Tsuji
Central Laboratories for Frontier Technology, Kirin Holdings Company Limited, 1 13 5 Fukuura Kanazawa ku, Yokohama shi, Kanagawa, Japan
J Agric Food Chem 60:6197-203. 2012..We term this means of removing iron the "ATY-PA" method. Sensory analysis indicated that fishy aftertaste in wine-seafood pairings was not perceived if the wine had been pretreated with both ATY cells and phytic acid...
Identification and characterization of genes involved in glutathione production in yeastTakahiro Suzuki
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, 1 13 5 Fukuura Kanazawa ku, Yokohama shi, Kanagawa 236 0004, Japan
J Biosci Bioeng 112:107-13. 2011..Moreover, overexpression of GSH1, CYS4, and DEF1 also increased glutathione production in Candida utilis. Taken together, these results will significantly contribute to more effective industrial production of glutathione using yeasts...
Ethanol production from xylose by a recombinant Candida utilis strain expressing protein-engineered xylose reductase and xylitol dehydrogenaseHideyuki Tamakawa
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, Yokohama, Kanagawa, Japan
Biosci Biotechnol Biochem 75:1994-2000. 2011..utilis indicated that the introduction of CsheXDH was essential, while overexpression of CsheXR K275R/N277D improved efficiency of ethanol production...
Efficient production of L-lactic acid by Crabtree-negative yeast Candida boidiniiFumi Osawa
Central Laboratories for Frontier Technology, Kirin Holdings Co Ltd, Kanagawa 236 0004, Japan
Yeast 26:485-96. 2009..Optimizing the conditions for batch culture in a 5 l jar-fermenter resulted in an L-lactic acid production reaching 85.9 g/l within 48 h. This productivity (1.79 g/l/h) is the highest thus far reported for L-lactic acid-producing yeasts...
Construction of a Candida utilis strain with ratio-optimized expression of xylose-metabolizing enzyme genes by cocktail multicopy integration methodHideyuki Tamakawa
Central Laboratories for Frontier Technology, Kirin Holdings Co, Ltd, 1 13 5 Fukuura Kanazawa ku, Yokohama, Kanagawa 236 0004, Japan Electronic address
J Biosci Bioeng 115:532-9. 2013..2 g/L of ethanol, yielding 0.402 g ethanol/g xylose. This result provides that C. utilis may be a good candidate as a host for ethanol production from xylose...
Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiaeSatoshi Yoshida
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, 113 0033 Tokyo, Japan
Curr Biol 12:944-50. 2002..We conclude that Cdc14 is released from the nucleolus at the onset of anaphase in a CDC5-dependent manner and that MEN factors possibly regulate Cdc14 release from the SPB...
Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesisSatoshi Yoshida
Department of Pediatric Oncology, Dana Farber Cancer Institute and Division of Hematology Oncology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Science 313:108-11. 2006..This role of Cdc5 (Polo-like kinase) in regulating Rho1 is likely to be relevant to cytokinesis and asymmetric cell division in other organisms...
Yeast formins Bni1 and Bnr1 utilize different modes of cortical interaction during the assembly of actin cablesShawnna M Buttery
Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
Mol Biol Cell 18:1826-38. 2007..In summary, our results indicate that formins can have distinct modes of cortical interaction during actin cable assembly...
A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4Sheng Xue Xie
Biotechnology Research Center, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Kosugi, Toyama 939 0398, Japan
Biochemistry 42:12056-66. 2003..e., NHase and amidase, and their regulatory and activator proteins. We report here the existence of an aldoxime dehydratase genetically linked with NHase and amidase, and responsible for the metabolism of alkylaldoxime in R. globerulus...
Ras recruits mitotic exit regulator Lte1 to the bud cortex in budding yeastSatoshi Yoshida
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan
J Cell Biol 161:889-97. 2003..These results suggest that Lte1 is a downstream effector protein of Ras in mitotic exit and that the Ras GEF domain of Lte1 is not essential for mitotic exit but required for its localization...
Budding yeast Cdc5 phosphorylates Net1 and assists Cdc14 release from the nucleolusSatoshi Yoshida
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Tokyo 113 0033, Japan
Biochem Biophys Res Commun 294:687-91. 2002..We also provide evidence that the critical function of Cdc5, other than Cdc14 liberation, exists in late mitotic events...
Plugging the GAP between cell polarity and cell cycleSatoshi Yoshida
Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
EMBO Rep 9:39-41. 2008
Extremely low dose ionizing radiation up-regulates CXC chemokines in normal human fibroblastsAkira Fujimori
Environmental and Toxicological Sciences Research Group, Research Center for Radiation Safety, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage, Chiba, Japan
Cancer Res 65:10159-63. 2005..In addition, our comprehensive approach using a novel expression profiling method is a powerful strategy to explore biological functions associated with very low levels of toxic agents...
MEN signaling: daughter bound pole must escape her mother to be fully activeSatoshi Yoshida
Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Hematology/Oncology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Dev Cell 9:168-70. 2005..The success of this process is monitored by a checkpoint-signaling mechanism. Two recent papers in Molecular Cell reveal an important new facet of this signal transduction pathway...
Polymerase chain reaction for identification of aldoxime dehydratase in aldoxime- or nitrile-degrading microorganismsYasuo Kato
Biotechnology Research Center, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Kosugi, Toyama 939-0398, Japan
FEMS Microbiol Lett 246:243-9. 2005..K-9 led to identify an Oxd having a new primary structure. Thus, the PCR-based analysis of oxd gene is a useful tool to detect and analyze the "aldoxime-nitrile pathway" in nature, since Oxd is the key enzyme for the pathway...
A pilot study of a Kampo formula, EH0202, with intriguing results for menopausal symptomsTakahisa Ushiroyama
Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan
J Altern Complement Med 10:397-9. 2004..To investigate the effects of EH0202, a Japanese herbal supplement, on the immune and endocrine systems in women with menopausal symptoms...
