Affiliation: Kinki University
Teramura T, Onodera Y, Mihara T, Hosoi Y, Hamanishi C, Fukuda K. Induction of mesenchymal progenitor cells with chondrogenic property from mouse-induced pluripotent stem cells. Cell Reprogram. 2010;12:249-61 pubmed publisher
..The present study demonstrates the property of iPS cells as an alternative candidate for treatment of articular disorders, and suggests an effective approach for preparing chondrocyte from iPS cells. ..
Takehara T, Teramura T, Onodera Y, Hamanishi C, Fukuda K. Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells. Stem Cells Dev. 2012;21:1239-49 pubmed publisher
..Our data provide evidence that oxygen concentration is an important factor for establishment of the EpiSC-specific state. ..
Teramura T, Matsuda K, Takehara T, Shinohara K, Miyashita Y, Mieno Y, et al
. Laser-assisted cell removing (LACR) technology contributes to the purification process of the undifferentiated cell fraction during pluripotent stem cell culture. Biochem Biophys Res Commun. 2018;503:3114-3120 pubmed publisher
..Our results suggested that LACR technology is a novel approach for stem cell processing in regenerative medicine. ..
Teramura T, Onodera Y, Murakami H, Ito S, Mihara T, Takehara T, et al
. Mouse androgenetic embryonic stem cells differentiated to multiple cell lineages in three embryonic germ layers in vitro. J Reprod Dev. 2009;55:283-92 pubmed
Teramura T, Onodera Y, Takehara T, Frampton J, Matsuoka T, Ito S, et al
. Induction of functional mesenchymal stem cells from rabbit embryonic stem cells by exposure to severe hypoxic conditions. Cell Transplant. 2013;22:309-29 pubmed publisher
..These results support the notion that exposing ESCs to severe hypoxic conditions during differentiation can be used as a strategy for the preparation of functional MSCs from ESCs. ..
Teramura T, Takehara T, Onodera Y, Nakagawa K, Hamanishi C, Fukuda K. Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells. Biochem Biophys Res Commun. 2012;417:836-41 pubmed publisher
..These results clearly suggested that the Rho/ROCK is a potent primary effector of mechanical stress in the pluripotent stem cells and it participates to pluripotency-related signaling cascades as an upper stream regulator. ..