Research Topics
| Kiyotaka OkunoSummaryAffiliation: Kinki University Country: Japan Publications
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Detail Information
Publications
Pylorotomy in pylorus-preserving pancreaticoduodenectomyTakuya Nakai
First Department of Surgery, Kinki University School of Medicine, Osaka, Japan
Hepatogastroenterology 53:947-9. 2006..The incidence of delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy has been reported to be 30% to 70%...
Recent advances in active specific cancer vaccine treatment for colorectal cancerKiyotaka Okuno
Department of Surgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama 589 8511, Japan
Curr Pharm Biotechnol 13:1439-45. 2012..The preliminary study yielded promising results regarding specific T cell responses to peptides and survival benefits. In this review, we summarize these results and discuss future perspectives...
Efficacy of orally administered Lentinula edodes mycelia extract for advanced gastrointestinal cancer patients undergoing cancer chemotherapy: a pilot studyKiyotaka Okuno
Department of Surgery, Kinki University School of Medicine, Osaka, Japan
Asian Pac J Cancer Prev 12:1671-4. 2011..These results suggest that concomitant use of LEM with chemotherapy can decrease the incidence of adverse effects from cancer chemotherapy among patients with advanced cancer...
Surgical treatment for digestive cancer. Current issues - colon cancerKiyotaka Okuno
Division of Colorectal Surgery, Department of Surgery, Kinki University School of Medicine, Osaka Sayama, Japan
Dig Surg 24:108-14. 2007..5 times in the last 25 years. In this review, the recent results of surgical treatment for colonic cancer and the future perspectives in Japan are described...
Prognostic factors in gastrointestinal perforationKiyotaka Okuno
Department of Surgery, Kinki University School of Medicine, Osaka Sayama, Japan
Hepatogastroenterology 58:1598-602. 2011..Postoperative complications associated with gastrointestinal (GI) perforation may lead to a poor prognosis. The goal of the study was to identify factors required for the establishment of appropriate perioperative procedures in such cases...
Comparison of long-term functional results of colonic J-pouch and straight anastomosis after low anterior resection for rectal cancer: a five-year follow-upJin ichi Hida
First Department of Surgery, Kinki University School of Medicine, Osaka, Japan
Dis Colon Rectum 47:1578-85. 2004..This prospective study compares the functional outcome of colonic J-pouch and straight anastomosis five years after low anterior resection for rectal cancer...
Long-term functional outcome of colonic J-pouch reconstruction after low anterior resection for rectal cancerJin-ichi Hida
Department of Surgery, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan
Surg Today 36:441-9. 2006....
Long-term functional changes after low anterior resection for rectal cancer compared between a colonic J-pouch and a straight anastomosisJin ichi Hida
Department of Surgery, Kinki University School of Medicine, 377 2, Ohno Higashi, Osaka Sayama Osaka 589 8511, Japan
Hepatogastroenterology 54:407-13. 2007..We prospectively compared changes in function between colonic J-pouch and straight anastomoses from 1 to 5 years after low anterior resection for rectal cancer...
Number versus distribution in classifying regional lymph node metastases from colon cancerJin-ichi Hida
Department of Surgery, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan
J Am Coll Surg 201:217-22. 2005..0% in pN1 and 45.0% in pN2 disease. CONCLUSIONS: In the classification of regional node metastases from colon cancer, the JGR classification showed a wider range in distribution and 5-year survival rate compared with the TNM system...
Depth of mesorectal invasion has prognostic significance in T3N0 low rectal cancerTadao Tokoro
Department of Surgery, Kinki University School of Medicine, 377 2 Oohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
Hepatogastroenterology 56:124-7. 2009..To investigate mesorectal fat invasion as a prognostic factor for T3N0 low rectal adenocarcinoma following sharp mesorectal excision...
Optimal ligation level of the primary feeding artery and bowel resection margin in colon cancer surgery: the influence of the site of the primary feeding arteryJin ichi Hida
Department of Surgery, Kinki University School of Medicine, Osaka, Japan
Dis Colon Rectum 48:2232-7. 2005..However, there is little evidence to unequivocally support such extensive lymphovascular resection...
Immunological evaluation of personalized peptide vaccination in combination with UFT and UZEL for metastatic colorectal carcinoma patientsTakashi Hattori
Department of Surgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
Cancer Immunol Immunother 58:1843-52. 2009..0215). The safety and immunological responsiveness of the present therapy suggest that this combination would be of clinical benefit for mCRC patients, and further trials are merited...
Long-term functional outcome of low anterior resection with colonic J-pouch reconstruction for rectal cancer in the elderlyJin ichi Hida
First Department of Surgery, Kinki University School of Medicine, Osaka, Japan
Dis Colon Rectum 47:1448-54. 2004..This study evaluated the function of colonic J-pouch reconstruction in elderly patients aged 75 years or older...
Osteopontin induced by macrophages contribute to metachronous liver metastases in colorectal cancerMotohiro Imano
Department of Surgery, Kinki University Faculty of Medicine, Ohno Higashi Osaka Sayama, Osaka, Japan
Am Surg 77:1515-20. 2011..31, m-LV 28.2 ± 3.18, P < 0.05). These results suggest that the risk of metachronous liver metastasis could be well predicted by immunohistochemical staining of OPN in the central areas, and CD68 in the invasive margins of tumors...
[General considerations in nodule-aggregating lesions of the colon]Tadao Tokoro
Department of Surgery, Kinki University School of Medicine
Nippon Rinsho 61:282-5. 2003
An immunohistochemical study of osteopontin in pigment gallstone formationMotohiro Imano
Department of Surgery, Kinki University School of Medicine, Osaka, Japan
Am Surg 76:91-5. 2010..Our results indicate that Opn, an acidic glycoprotein from the gallbladder epithelium, seems to be involved in lithiasis. Opn from macrophages and/or the epithelium seems to help form the matrix protein...
Role of sialyl Lewis X in liver metastasis in view of liver-associated immunityKiyotaka Okuno
First Department of Surgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama 589 8511, Japan
Hepatogastroenterology 50:756-60. 2003..However, little is known about the interaction between sialyl Lewis X and hepatic immune cells. We evaluated the role of sialyl Lewis X in liver metastasis in view of liver-associated immunity...
Effect of chemoradiotherapy for neural invasion in an advanced esophageal cancerAkira Tanaka
Surgery, Sakai Hospital, School of Medicine, Kinki University, Sakai, Osaka 590 0132, Japan
Hepatogastroenterology 55:963-6. 2008..This study examined utility of chemoradiotherapy for neural invasion, a risk factor for local recurrence, and a poor prognosis factor...
[Japanese General Rules and TNM System in the regional lymph node classification of colon cancer]Jin-ichi Hida
Department of Surgery, Kinki University School of Medicine
Nippon Rinsho 61:262-8. 2003
Pouch operation for rectal cancerJin ichi Hida
Department of Surgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka, 589 8511, Japan
Surg Today 40:307-14. 2010..At a time when the indications for abdominoperineal excision appear to be reduced for low rectal cancer, the demand for colonic J-pouch reconstruction (the best technique in pouch operations) is therefore likely to increase...
High ligation of the inferior mesenteric artery in rectal cancer surgeryJin ichi Hida
Department of Surgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
Surg Today 43:8-19. 2013....
Clinical characteristics of hepatitis B core antibody-positive hepatocellular carcinomaTakuya Nakai
First Department of Surgery, Kinki University School of Medicine, 377-2, Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan
World J Surg 26:700-3. 2002..Although HBsAg and HCVAb are used for conventional screening of patients with hepatic disorders, we believe that screening is also necessary in patients with positive HBcAb titers for early detection of HCC...
Ability of bivariate cytokeratin and deoxyribonucleic acid flow cytometry to determine the biologic aggressiveness of resectable non-small cell lung cancerHiroshi Otsuka
First Department of Surgery, Kinki University School of Medicine, 377 2 Ohnogashi, Osaka Sayama, Osaka 589 8511, Japan
J Thorac Cardiovasc Surg 124:293-8. 2002..The purpose of this study was to clarify the significance of bivariate cytokeratin and DNA flow cytometry for analysis of the biologic aggressiveness of resectable non-small cell lung cancer...
[Intracellular glutathione (GSH) of monocytes (Mo) directs the development of peritumoral stroma in patients with colon carcinoma]Tomohiko Matsuzaki
Dept of Surgery, Kinki University School of Medicine
Gan To Kagaku Ryoho 32:1537-9. 2005..2. The mean stroma score was 60.8. There was a significant correlation between the GSH score and the stroma score (r = 0.421, p < 0.05). CONCLUSION: The monocyte GSH level may serve as a predictor of stromal growth...
A series of immune responses leading to the induction of T cell IL-12/IL-18 responsiveness in patients with relatively large tumor burdensKazuko Uno
Louis Pasteur Center for Medical Research, 103 5, Tanaka monzen cho, Sakyo ku, Kyoto, Kyoto 606 8225, Japan
Cancer Immunol Immunother 52:33-40. 2003....
[A phase I study of combination-therapy using personalized peptide vaccine and UFT/UZEL for advanced or recurrent colorectal cancer]Takashi Hattori
Dept. of Surgery, Kinki University School of Medicine
Gan To Kagaku Ryoho 33:1745-7. 2006..Moreover, the use of UFT/UZEL does not normally interfere with the normal course of immune-therapy...
