- Progressive renal tubular dysfunction associated with long-term use of tenofovir DFEi Kinai
Department of Hematology, Ogikubo Hospital, Tokyo, Japan 167 8515
AIDS Res Hum Retroviruses 25:387-94. 2009..Prolonged treatment with TDF caused progressive renal tubular dysfunction as well as a modest decline in GFR. If U-BMG levels >10,000 microg/liter and %TRP values <80% are observed, discontinuing TDF may be beneficial...
- Renal tubular toxicity associated with tenofovir assessed using urine-beta 2 microglobulin, percentage of tubular reabsorption of phosphate and alkaline phosphatase levelsEi Kinai
Department of Hematology, Ogikubo Hospital, Tokyo, Japan
AIDS 19:2031-3. 2005..0 to 91.1% and alkaline phosphatase increased from 294 to 365 U/l, whereas serum creatinine and phosphorus remained largely unchanged. Patients with the above findings should be monitored carefully for renal tubular toxicity...