Research Topics
Species | Shigeru WatanabeSummaryAffiliation: Keio University Country: Japan Publications
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Detail Information
Publications
Lesions in the basal ganglion and hippocampus on performance in a Wisconsin Card Sorting Test-like task in pigeonsShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Physiol Behav 85:324-32. 2005..The present results suggest that LPO has the function of cognitive flexibility...
Formation of linear dominance relationship in captive jungle crows (Corvus macrorhynchos): implications for individual recognitionEi Ichi Izawa
Department of Psychology, Keio University, Tokyo 108 8345, Japan
Behav Processes 78:44-52. 2008....- Effects of sedative and non-sedative H1 antagonists on cognitive tasks: behavioral and near-infrared spectroscopy (NIRS) examinationsTakeo Tsujii
Center for Integrated Research on the Mind, Keio University, Mita 3 1 7, Minato ku, Tokyo 108 0073, Japan
Psychopharmacology (Berl) 194:83-91. 2007..However, the neural correlates of the poorer performance associated with first-generation H1-receptor antagonists remain unknown... - Towards a "virtual pigeon": a new technique for investigating avian social perceptionShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, 108, Japan
Anim Cogn 9:271-9. 2006..The results of an additional partial occlusion test suggest that the subjects used head movement as a cue for the usual vs. unusual CG pigeon discrimination... - Effects of partial hippocampal lesions by ibotenic acid on repeated acquisition of spatial discrimination in pigeonsShigeru Watanabe
Department of Psychology, Keio University, Tokyo, Japan
Rev Neurosci 17:29-41. 2006.... - Social factors in conditioned place preference with morphine in miceShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Pharmacol Biochem Behav 103:440-3. 2013..0mg/kg dose. Results from these experiments differ from previous results concerning methamphetamine, in which a drug-free partner did not enhance the drug's effect... - Distress of mice induces approach behavior but has an aversive property for conspecificsShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Processes 90:167-73. 2012..Thus, distress in mice induced short-term approach behavior in conspecifics but also had an aversive property... - Effects of hippocampal lesions on conditional spatial discrimination in pigeonsShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Physiol Behav 77:183-7. 2002..These results suggest that the pigeon hippocampus does not play a role in conditional spatial discrimination... - Auditory cued spatial learning in miceS Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Physiol Behav 92:906-10. 2007..Results demonstrate the ability of auditory cued spatial navigation in mice... - Discrimination of painting style and quality: pigeons use different strategies for different tasksShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Tokyo 108, Japan
Anim Cogn 14:797-808. 2011..Thus, the pigeons discriminated good and bad paintings based mostly on global configuration cues in this case. These results suggest that the pigeons use different cues for different discriminations... - Drug-social interactions in the reinforcing property of methamphetamine in miceShigeru Watanabe
Department of Psychology, Keio University, Minato ku, Tokyo, Japan
Behav Pharmacol 22:203-6. 2011..In contrast, the control-paired group did not show such a social enhancement effect. These results suggest that sharing the same experience is crucial for the social enhancement of the methamphetamine reinforcing effect... - Effects of hippocampal lesions on acquisition and retention of spatial learning in zebra finchesShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Brain Res 155:147-52. 2004..Therefore, the birds with hippocampal damage used an alternative, nonspatial memory-based strategy to find the food... - Integration of auditory and visual information in human face discrimination in pigeons. Behavioral and anatomical studyShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Brain Res 207:61-9. 2010..Thus, the visual and auditory systems should be integrated in higher associative area, such as nidopallium caudo-lateralis (NCL) or in an earlier stage, such as the midbrain in the avian brain... - Visual Wulst analyses "where" and entopallium analyses "what" in the zebra finch visual systemShigeru Watanabe
Department of Psychology, Keio University, Mita 2 25 45, Minato ku, Tokyo, Japan
Behav Brain Res 222:51-6. 2011..The entopallium is thus involved if the food source is identified by a pattern, and the Wulst if it has to be found by spatial cues... - Animal logics: decisions in the absence of human languageShigeru Watanabe
Department of Psychology, Keio University, Mita 2-15-45, Minato-ku, Tokyo 108, Japan
Anim Cogn 9:235-45. 2006 - Discrimination of consonance and dissonance in Java sparrowsS Watanabe
Department of Psychology, Keio University, Minato ku, Tokyo 180, Japan
Behav Processes 70:203-8. 2005..In summary, Java sparrows were able to discriminate between consonances and dissonances and demonstrated generalization to new combinations, they do not discriminate the same consonances and dissonances... 
Empathy and reversed empathy of stress in miceShigeru Watanabe
Department of Psychology, Keio University, Tokyo, Japan
PLoS ONE 6:e23357. 2011..This is the reversed-empathy. Level of corticosterone is the highest after the restrain with free-moving mates and lowest after the restrain with restrained mates...- Effects of lobus parolfactorius lesions on repeated acquisition of spatial discrimination in pigeonsS Watanabe
Department of Psychology, Keio University, Tokyo, Japan
Brain Behav Evol 58:333-42. 2001..Thus, the LPO lesions caused cognitive rigidity. These results are consistent with clinical observations of patients with basal ganglia disorders... - Language discrimination by Java sparrowsShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Processes 73:114-6. 2006..Thus, the birds distinguished between English and Chinese. Although auditory cues for the discrimination were not specified, this is the first evidence that non-mammalian species can discriminate human languages... - Effects of hippocampal lesions on spatial operant discrimination in pigeonsS Watanabe
Department of Psychology, Keio University, Tokyo, Japan
Behav Brain Res 103:77-84. 1999..The subjects maintained the discrimination. These results suggest that the avian hippocampus plays a crucial role in acquisition of spatial discrimination... - Effects of hippocampal lesions on repeated acquisition of spatial discrimination in pigeonsS Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Brain Res 120:59-66. 2001..These results suggest that the avian hippocampus have a crucial role in acquisition of spatial discriminations... - Pigeons can discriminate "good" and "bad" paintings by childrenShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo 108, Japan
Anim Cogn 13:75-85. 2010.... - Pattern discrimination is affected by entopallial but not by hippocampal lesions in zebra finchesShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Brain Res 190:201-5. 2008..Taken together, our experiments prove that the avian hippocampus is involved in spatial learning, but not in pattern discrimination tasks... - Longitudinal study of spatial working memory development in young childrenTakeo Tsujii
Center for Advanced Research on Logic and Sensibility, Keio University, Tokyo, Japan
Neuroreport 20:759-63. 2009..We therefore offer the first demonstration of the developmental changes in frontal cortical activation during spatial working memory tasks during the preschool period... - Antihistamine effects on prefrontal cortex activity during working memory process in preschool children: a near-infrared spectroscopy (NIRS) studyTakeo Tsujii
Center for Advanced Research on Logic and Sensibility CARLS, Mita 3 1 7, Minato ku, Tokyo 108 0073, Japan
Neurosci Res 67:80-5. 2010..Also discussed is the utility of the NIRS technique in neuropsychopharmacological studies of children... - Effects of sedative and nonsedative antihistamines on prefrontal activity during verbal fluency task in young children: a near-infrared spectroscopy (NIRS) studyTakeo Tsujii
Center for Advanced Research on Logic and Sensibility, Keio University, Mita 3 1 7, Minato ku, Tokyo, 108 0073, Japan
Psychopharmacology (Berl) 207:127-32. 2009..Antagonists of histamine H(1) receptors (antihistamines) are widely used for the treatment of allergic disorders in children. These drugs' sedative effect on brain function, however, has been mostly examined in adults... - Effects of aging on hemispheric asymmetry in inferior frontal cortex activity during belief-bias syllogistic reasoning: a near-infrared spectroscopy studyTakeo Tsujii
Center for Advanced Research on Logic and Sensibility CARLS, Keio University, Tokyo, Japan
Behav Brain Res 210:178-83. 2010..Thus, we demonstrate, for the first time, age-related differences in neural activity associated with belief-bias reasoning... - Spatial learning deficits after the development of dorsomedial telencephalon lesions in goldfishKotaro Saito
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo 108 8345, Japan
Neuroreport 15:2695-9. 2004..These results suggest that dorsomedial lesions selectively caused impairment in the retention of spatial learning... - Effects of hippocampal lesions on conditional discriminations in ratsYusuke Otsuka
Department of Psychology, Keio University, Tokyo, Japan
Rev Neurosci 17:147-55. 2006.... - Neural correlates of dual-task effect on belief-bias syllogistic reasoning: a near-infrared spectroscopy studyTakeo Tsujii
Center for Advanced Research on Logic and Sensibility, Keio University, Mita 3 1 7, Minato ku, Tokyo 108 0073, Japan
Brain Res 1287:118-25. 2009..We therefore offer the first demonstration of neural correlates of dual-task effect on IFC activity in belief-bias reasoning... - The role of inferior frontal cortex in belief-bias reasoning: an rTMS studyTakeo Tsujii
Center for Advanced Research on Logic and Sensibility CARLS, Keio University, Mita 3 1 7, Minato ku, Tokyo 108 0073, Japan
Neuropsychologia 48:2005-8. 2010..Subjects whose left IFC was impaired by rTMS may not suffer from interference by irrelevant semantic processing. This study demonstrates for the first time the roles of left and right IFC in belief-bias reasoning using an rTMS approach... - Deficits in acquisition of spatial learning after dorsomedial telencephalon lesions in goldfishKotaro Saito
Department of Psychology, Keio University, Mita 3 1 7 7F, Minato ku, Tokyo 108 0073, Japan
Behav Brain Res 172:187-94. 2006..Latent learning in the habituation sessions, however, eliminated the effects of the DM lesions on spatial learning. The present study suggests that the DM plays a critical role in acquisition of spatial learning... - Spatial memory activation of the parietal cortex measured with near-infrared spectroscopic imaging in the finger-maze of the Morris water maze analogue for humansKotaro Saito
Department of Psychology, Keio University, Minato ku, Tokyo 108 8345, Japan
Rev Neurosci 17:227-38. 2006..In the probe test, only the dorsolateral prefrontal regions were activated. These results suggest that the parietal cortex is critical for acquisition of spatial memory... - Pharmacological effects on mirror approaching behavior and neurochemical aspects of the telencephalon in the fish, medaka (Oryzias latipes)Tatsuya Tsubokawa
Keio University, Yokohama, Japan
Soc Neurosci 4:276-86. 2009..Mirror approaching behavior therefore revealed a close relationship with the action of the GABA-nergic system and not the dopaminergic system in the medaka telencephalon... - Two successive neurocognitive processes captured by near-infrared spectroscopy: prefrontal activation during a computerized plus-shaped maze taskHiromtisu Miyata
Japan Society for the Promotion of Science, Tokyo, Japan
Brain Res 1374:90-9. 2011..The results also testify to the effective NIRS recording, while the participants were moving a computer-generated stimulus by actually making finger touches to the monitor... - Crows cross-modally recognize group members but not non-group membersNoriko Kondo
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo 108 8345, Japan
Proc Biol Sci 279:1937-42. 2012..These results indicate that crows spontaneously associate visual and auditory information of group members but not of non-group members, which is a demonstration of cross-modal audiovisual recognition of group members in birds... - IMHV lesions caused deficits in conspecific discrimination in chicks but not in adult quailFuyumi Awaya
Department of Psychology, Keio University, Mita 2-15-45, Minato-ku, Tokyo 108-0073, Japan
Neuroreport 14:1511-4. 2003..However, the chicks receiving bilateral IMHV lesions before CIP did not show any preference for either stimulus quail. These results suggest that there is a functional difference in IMHV between chicks and adults... - Mice recognize the center of an enclosureNaomi Inoue
Department of Psychology, Keio University, 2 2 24 Mita, Minato ku, Tokyo, 108 8345, Japan
Behav Processes 91:141-4. 2012..This indicates that the experimental group localized the center not by reference to the absolute distance from the corners but by equal distances from all walls (geometric center)... - Dissociable roles of the medial prefrontal cortex, the anterior cingulate cortex, and the hippocampus in behavioural flexibility revealed by serial reversal of three-choice discrimination in ratsYutaka Kosaki
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Brain Res 227:81-90. 2012..These results extend our understanding of the contributions of the different nodes of the limbic cortico-striatal circuit to different aspects of behavioural flexibility... - Tool-use learning by common marmosets (Callithrix jacchus)Yumiko Yamazaki
The Graduate School of Sociology, Keio University, 201 Mita Toho Building, 3 1 7 Mita, Minato ku, Tokyo 108 0073, Japan
Exp Brain Res 213:63-71. 2011..The common marmoset is thus a model primate for such studies. This study sets the stage for future research to examine the biological mechanisms underlying the cognitive ability of tool use at the molecular and genetic levels... - Strategy of auditory discrimination of scale in Java sparrows: they use both "imagery" and specific cuesEriko Yamamoto
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Processes 77:1-6. 2008..Experiment 2 confirmed that the stimulus duration was a discriminative cue for both groups, suggesting that the birds also acquired discrimination using only specific cues... - Effects of Wulst and ectostriatum lesions on repeated acquisition of spatial discrimination in pigeonsShigeru Watanabe
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Brain Res Cogn Brain Res 17:286-92. 2003..The Wulst lesions disrupted the acquisition of discrimination, while the ectostriatal lesions did not... - Neural correlates of belief-bias reasoning under time pressure: a near-infrared spectroscopy studyTakeo Tsujii
Center for Advanced Research on Logic and Sensibility CARLS, Keio University, Tokyo, Japan
Neuroimage 50:1320-6. 2010..We therefore offer the first demonstration of neural correlates of time-pressure effect on the IFC activity in belief-bias reasoning... - In vivo measurement of superoxide in the cerebral cortex during anoxia-reoxygenation and ischemia-reperfusionKeiji Yamaguchi
Department of Neurology, School of Medicine, Keio University, Tokyo, Japan
Keio J Med 51:201-7. 2002..01) and then increased at 20 and 25 minutes after reperfusion (p < 0.05). These results indicate that superoxide generation decreases during anoxia and ischemia and then increases within 20 minutes after reoxygenation or reperfusion... - Delayed matching-to-position performance in C57BL/6N miceKazuhiro Goto
Japan Society for the Promotion of Science, Japan
Behav Processes 84:591-7. 2010..Overall, the results replicated the effects of parametric manipulations reported in other species, and thus, our findings validate the efficacy of the task for assessing spatial working memory in laboratory mice... - Within-session changes in licking as a function of sucrose concentration in common marmosetsTaku Ishii
Mita Toho Building 7F, Centre for Advanced Research for Logic and Sensibility, Keio University, 3 1 5 Mita, Minato ku, Tokyo 108 0073, Japan
Behav Processes 84:536-40. 2010..The cumulative records of licking for individual sessions revealed that a break-and-run pattern of licking sometimes dominated after a licking rate slowed down, and that this pattern could disturb the linear relation... - Effects of ectostriatal lesions on discriminations of conspecific, species and familiar objects in pigeonsS Watanabe
Department of Psychology, Keio University Mita, Tokyo, Japan
Behav Brain Res 81:183-8. 1996..These results suggest dissociation between conspecific and species discriminations. The results of the familiar object discrimination indicate factor of familiarity in the conspecific discrimination... - Tetrodotoxin-sensitive persistent current boosts the depolarization of retinal amacrine cells in goldfishS Watanabe
Department of Physiology, Keio University School of Medicine, Tokyo, Japan
Neurosci Lett 278:97-100. 2000..Therefore, it is highly likely that the TTX-sensitive persistent current is a booster of the excitatory postsynaptic potential in amacrine cells... - Abnormalities of basal cell keratin in epidermolysis bullosa simplex do not affect the expression patterns of suprabasal keratins and cornified cell envelope proteinsY Sasaki
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
Arch Dermatol Res 290:591-7. 1998..Thus, the abnormality in basal cell keratins in patients with EBS did not appear to alter the patterns of expression of the keratins and CCE precursor proteins... - Impact of drug alteration to maintain rhythm control in paroxysmal atrial fibrillation. - Subanalysis from J-RHYTHM study -Ayaka Endo
Keio University School of Medicine, Tokyo, Japan
Circ J 74:870-5. 2010..The aim was to describe how antiarrhythmics (AAs) were altered in the rhythm control arm and whether altering AAs would impact long-term outcomes... - Prosody discrimination by songbirds (Padda oryzivora)Nozomi Naoi
Department of Psychology, Keio University, Tokyo, Japan
PLoS ONE 7:e47446. 2012..Moreover, unlike Japanese speakers, Java sparrows used the first part of the utterance as the discrimination cue... - Reading speed, comprehension and eye movements while reading Japanese novels: evidence from untrained readers and cases of speed-reading traineesHiromitsu Miyata
Japan Society for the Promotion of Science, Tokyo, Japan
PLoS ONE 7:e36091. 2012..In addition to normal untrained readers, three middle-level trainees and one high-level expert on this method were included for the two case studies... - Discriminative and reinforcing properties of paintings in Java sparrows (Padda oryzivora)Yuko Ikkatai
Department of Psychology, Keio University, Mita 2 15 45, Tokyo, 108 8345, Japan
Anim Cogn 14:227-34. 2011..However, the reinforcing properties vary from individual to individual. This is the first report demonstrating reinforcing properties of visual artworks in non-human animals... - Left-right asymmetry defect in the hippocampal circuitry impairs spatial learning and working memory in iv miceKazuhiro Goto
Japan Society for the Promotion of Science, Tokyo, Japan
PLoS ONE 5:e15468. 2010..These results suggest that the L-R asymmetry of hippocampal circuitry is critical for the acquisition of reference memory and the retention of working memory... - Chronic food restriction enhances memory in mice--analysis with matched drive levelsTeruo Hashimoto
Department of Psychology, Faculty of Letters, Keio University, 2-15-45 Mita, Minato-ku, Tokyo 108-8345, Japan
Neuroreport 16:1129-33. 2005..These effects were subtle and were found at a later stage of learning. These findings suggest that chronic food restriction induces memory consolidation or resistance to memory reduction in addition to increased activity... - Discriminative and reinforcing stimulus properties of music for ratsY Otsuka
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Behav Processes 80:121-7. 2009..Most of the rats preferred white noise to the conspecific vocalization. Therefore, music has a discriminative stimulus property but not a clear reinforcing property for rats... - Optimal treatment strategy for patients with paroxysmal atrial fibrillation: J-RHYTHM StudySatoshi Ogawa
Department of Cardiology, Keio University, Tokyo, Japan
Circ J 73:242-8. 2009..However, mortality and cardiovascular morbidity were not affected by the treatment strategy (umin-CTR No. C000000106)... - Discrimination of moving video images of self by pigeons (Columba livia)Koji Toda
Department of Psychology, Keio University, Tokyo, Japan
Anim Cogn 11:699-705. 2008..The methodology used in the present experiment is an important step toward improving the experimental analysis of self-recognition in non-human animals... - Modulation of physical understanding by common marmosets (Callithrix jacchus)Yumiko Yamazaki
The Graduate School of Sociology, Keio University, 2F Mita Toho Building, 3 1 7 Mita, Tokyo, 108 0073, Japan
Anim Cogn 14:175-86. 2011..These findings suggest that marmosets' physical understanding may improve with experience... - Effects of telencephalic ablation on shoaling behavior in goldfishKazutaka Shinozuka
Department of Psychology, Keio University, Mita 2 15 45, Minato ku, Tokyo, Japan
Physiol Behav 81:141-8. 2004..Lesions in either portion had no effect and no simple visual or motor deficits were seen. These results suggest that the ventral part of the telencephalon mediates shoaling behavior... - Task-dependent strain difference of spatial learning in C57BL/6N and BALB/c miceM Yoshida
Department of Psychology, Keio University, Mita 2-15-45, Minato-ku, Tokyo 108-8345, Japan
Physiol Behav 73:37-42. 2001..The poor performance of the BALB/cA in the water maze task may reflect a weak motivation, escaping from water, rather than the poor spatial memory in this strain... - Foot-use laterality in the Japanese jungle crow (Corvus macrorhynchos)Ei Ichi Izawa
Department of Psychology, Keio University, Tokyo 108 8345, Japan Japan Society for Promotion of Science, Tokyo 108 8345, Japan
Behav Processes 69:357-62. 2005..These results suggest that jungle crows have strong individual-level laterality in foot-use behaviour... - Relationship between aortic calcification and stroke in a mass screening program using a mobile helical computed tomography unitYasutaka Itani
The Japanese Society of CT Screening, Tokyo, Japan
Circ J 70:733-6. 2006..However, the relationship between stroke and aortic calcification (AoC) detected during a mass screening using a mobile helical computed tomography (CT) unit remains unknown... - Modulation of oscillatory neural activities by cholinergic activation of interneurons in the olfactory center of a terrestrial slugS Watanabe
Laboratory of Neurobiophysics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, 113 0033, Tokyo, Japan
Brain Res 896:30-5. 2001..Application of ACh also resulted in a reduction of the oscillation amplitude in the olfactory nerve, suggesting that the frequency modulation in the oscillatory network could change the activities in the follower neurons... - The role of myelination in learning performance observed in two strains of myelin-deficient mutant mice (shiverer and mld)K Inagawa
Department of Psychology, Keio University, Tokyo, Japan
Behav Neural Biol 50:184-92. 1988..Both mutant mice showed no deficits in the radial maze performance, which is though to show the natural foraging behavior of rodents. These results suggest that myelin formation is related to learning but not to natural behavior... - The effects of Malassezia yeasts on cytokine production by human keratinocytesS Watanabe
Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan
J Invest Dermatol 116:769-73. 2001..These differences may reflect the different inflammatory responses in Malassezia-associated dermatoses, resulting in different clinical and pathologic manifestations... - Aortic calcification detected in a mass chest screening program using a mobile helical computed tomography unit. Relationship to risk factors and coronary artery diseaseYasutaka Itani
The Society of Thoracic CT Screening, Tokyo, Japan
Circ J 68:538-41. 2004.... - Near-field visual acuity in Japanese jungle crows (Corvus macrorhynchos)K Yamamoto
Department of Psychology, Keio University, 2 15 45 Mita, Minato ku, Tokyo 108 8345, Japan
Physiol Behav 72:283-6. 2001..The average visual acuity was 8.4 cycles/degree. When compared with other birds, this result is better than that of pigeons, and worse than that of predators... - Increased fearfulness of Fyn tyrosine kinase deficient miceT Miyakawa
Department of Psychology, Faculty of Letters, University of Tokyo, Japan
Brain Res Mol Brain Res 27:179-82. 1994..These results indicate that fynz/fynz mice are hyperresponsive to fear-inducing stimuli... - Molecular analysis of CAP59 gene sequences from five serotypes of Cryptococcus neoformansY Nakamura
Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan
J Clin Microbiol 38:992-5. 2000..The molecular analysis of the CAP59 gene will provide useful information for the differentiation of serotypes of C. neoformans and for an understanding of their phylogenetic relationships... - Multiple processing of procathepsin L to cathepsin L in vivoK Ishidoh
Department of Biochemistry, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, 113, Japan
Biochem Biophys Res Commun 252:202-7. 1998..Percoll density gradient and fluorescence immunohistochemistry suggested that these three species of cathepsin L localize in the lysosomes where procathepsin L processing occurs... - Isolates of Cryptococcus neoformans serotype A and D developed on canavanine-glycine-bromthymol blue mediumY Nakamura
Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan
Mycoses 41:35-40. 1998..1 mmol l-1 of canavanine and 133 mmol l-1 of glycine. Three isolates of Cr. neoformans developed on CGB medium were also confirmed to be serotype A or D by the molecular analysis... - Leukotriene B(4) enhances tumour necrosis factor-alpha-induced CCL27 production in human keratinocytesN Kanda
Department of Dermatology, School of Medicine, Teikyo University, Tokyo, Japan
Clin Exp Allergy 37:1074-82. 2007..A lipid mediator leukotriene B(4) (LTB(4)) may be involved in the development of these allergic dermatoses. LTB(4) acts on cell surface G-protein-coupled receptors, BLT1 and BLT2... - Increased expression of Smad6 deteriorates murine acute experimental pancreatitis in two modelsH Nakamura
Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine, 1 1 Iseigaoka, Yahatanishi ku Kitakyushu 807 8555, Japan
Gut 57:788-98. 2008..Smad6 is implicated in the inhibition of bone morphogenetic protein signalling. However, the function of Smad6 in the pancreas remains obscure... - [The effect on other individual presentations of the goldfish by FG7142 injection]Yukika Nishimura
Department of Psychiatry, School of Medicine, Mie University, 2-174, Edobashi, Tsu, 514-8507 Japan
Nihon Shinkei Seishin Yakurigaku Zasshi 22:55-9. 2002..In contrast, the time spent was unchanged in the high-dose group (4 mg/kg). The subject fish motility was unchanged in all dose groups. These results are discussed in their relationship to predator avoidance... - An immnosuppressive drug, cyclosporine-A acts like anti-depressant for rats under unpredictable chronic stressChieko Fujisaki
Department of Pathology and Immunology, Tokyo Medical and Dental University Graduate School, Japan
J Med Dent Sci 50:93-100. 2003..Comparing the data of monoamines and their metabolites in the brain, cascades may be different between CsA and imipramine, although both of them showed antidepressive effect in behavioral tests... - Visual discrimination of normal and drug induced behavior in quails (Coturnix coturnix japonica)Yumiko Yamazaki
Biopsychologie, Institut für Kognitive Neurowissenschaft, Fakultat fur Psychologie, Ruhr Universitat Bochum, 44780 Bochum, Germany
Anim Cogn 7:128-32. 2004..They did not, however, show discriminative behavior according to the type and dosage of the drugs. Thus, they categorized the behavior not on the basis of degree of activity, but on the basis of abnormality... - Spatial memory and hippocampal function in a non-foodstoring songbird, the zebra finch (Taeniopygia guttata)Hans Joachim Bischof
Universitat Bielefeld, Fakultat Biologie, Bielefeld, Germany
Rev Neurosci 17:43-52. 2006..The IEG activation pattern in spatial memory experiments is compared with those in other learning experiments with zebra finches... - Solid-emissive fluorophores constructed by a non-planar heteropolycyclic structure with bulky substituents: synthesis and X-ray crystal structuresYousuke Ooyama
Department of Material Science, Faculty of Science, Kochi University, Akebono cho, Kochi 780 8520, Japan
Org Biomol Chem 5:1260-9. 2007..On the other hand, in the crystal of , the formation of continuous intermolecular CH[dot dot dot]S bonding between neighboring fluorophores was found to increase short pi-pi contacts and reduce the fluorescence intensity... - Auditory fear conditioning and conditioned stress raise NO(3) level in the AmygdalaTaku Sato
Department of Psychiatry, Kitasato University School of Medicine, Sagamihara, Japan
Neuropsychobiology 53:142-7. 2006..CONCLUSIONS: Although the sources of NO(3)(-) remain uncertain, these results suggest that nitric oxide is associated with auditory fear conditioning and the response to a conditioned stimulus... - Effects of intraperitoneally injected lithium, imipramine and diazepam on nitrate levels in rat amygdalaShuji Maruta
Department of Psychiatry, Kitasato University School of Medicine, Kanagawa, Japan
Psychiatry Clin Neurosci 59:358-61. 2005..Lithium significantly reduced, while imipramine raised, levels as compared with controls. These observations suggest that lithium and imipramine induce opposite effects on NO-related systems in the brain... - Amygdalic levels of dopamine and serotonin rise upon exposure to conditioned fear stress without elevation of glutamateMasamoto Yokoyama
Department of Psychiatry, Kitasato University School of Medicine, 2-1-1 Asamizodai, Sagamihara, Kanagawa 228-8520, Japan
Neurosci Lett 379:37-41. 2005..The periods of elevated dopamine and serotonin were longer on Day 1 than on Day 2. These results suggest that greater amounts of glutamate, dopamine and serotonin are necessary for acquisition than for recall of conditioned fear... - Enhancement of delayed release of dopamine in the amygdala induced by conditioned fear stress in methamphetamine-sensitized ratsTakaharu Suzuki
Department of Psychiatry, Kitasato University School of Medicine 2-1-1 Asamizodai, Kanagawa 228-8520, Sagamihara, Japan
Eur J Pharmacol 435:59-65. 2002.... - Effects of intraperitoneal administration of IFN-alpha for one, four, and fourteen days on amino acid levels in various rat brain regionsMasamoto Yokoyama
Department of Psychiatry, Kitasato University School of Medicine, 2-1-1 Asamizodai, Sagamihara, Kanagawa, 228-8520, Japan
J Interferon Cytokine Res 25:187-91. 2005..Further studies are necessary to determine if these effects of IFN-alpha on cerebral amino acids are involved in the pathophysiology of IFN-alpha-induced depression... - Polymorphism of dopamine receptor D4 exon I corresponding region in chickenAkinori Sugiyama
Faculty of Applied Biological Sciences, Gifu University, Japan
Zoolog Sci 21:941-6. 2004..This polymorphism, which is the first to be reported on a neurotransmitter-related gene in birds, would contribute significant information for elucidation of differences in behavioral traits in chicken breeds... - Chronic intraperitoneal injection of interferon-alpha reduces serotonin levels in various regions of rat brain, but does not change levels of serotonin transporter mRNA, nitrite or nitrateTaku Sato
Department of Psychiatry, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
Psychiatry Clin Neurosci 60:499-506. 2006..Further investigation is needed to determine exactly how this cytokine affects the central serotonin system and to assess whether a central serotonin abnormality is involved in interferon-induced depression...