- TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanismsGiichi Takaesu
Center for Integrated Medical Research, Keio University School of Medicine, Tokyo, Japan
PLoS ONE 7:e51073. 2012....
- TGFβ-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagyGiichi Takaesu
Center for Integrated Medical Research, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582 Japan
J Biochem 151:157-66. 2012..The decrease of p62/SQSTM1 induced by the knockdown of TAB2 and TAB3 is largely dependent on ATG5. These results suggest that TAB2 and TAB3 negatively regulate autophagy independently of TAK1 activity...