Affiliation: Keio University
Uchida T, Nishimoto K, Fukumura Y, Asahina M, Goto H, Kawano Y, et al
. Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study. Endocr Pathol. 2017;28:27-35 pubmed publisher
..The coordinated expression of steroidogenic enzymes in normal and adenoma cells was disturbed in ACC cells, resulting in the inefficient production of steroid hormones in relation to the large tumor volume. ..
Makita K, Nishimoto K, Kiriyama Kitamoto K, Karashima S, Seki T, Yasuda M, et al
. A Novel Method: Super-selective Adrenal Venous Sampling. J Vis Exp. 2017;: pubmed publisher
..The ssAVS method is not difficult for expert angiographers, and, thus, is recommended worldwide to treat PA cases for which cAVS does not represent a viable surgical treatment option. ..
Tamura A, Nishimoto K, Seki T, Matsuzawa Y, Saito J, Omura M, et al
. Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism. Mol Cell Endocrinol. 2017;441:134-139 pubmed publisher
Nishimoto K, Koga M, Seki T, Oki K, Gomez Sanchez E, Gomez Sanchez C, et al
. Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism. Mol Cell Endocrinol. 2017;441:124-133 pubmed publisher
..Immunohistochemistry for CYP11B2 and CYP11B1 has become an important tool for the diagnosis of and research on adrenocortical pathological conditions and suggests that APCCs may be the origin of aldosterone-producing adenoma. ..