Morio Matsumoto

Summary

Affiliation: Keio University
Country: Japan

Publications

  1. pmc Updates on surgical treatments for pediatric scoliosis
    Morio Matsumoto
    Department of Orthopedic Surgery, Keio University, Shinanomachi 35, Shinjuku, Tokyo, 160 8582, Japan
    J Orthop Sci 19:6-14. 2014
  2. doi request reprint Modic changes of the cervical spine in patients with whiplash injury: a prospective 11-year follow-up study
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Japan
    Injury 44:819-24. 2013
  3. pmc Acute respiratory failure due to hemothorax after posterior correction surgery for adolescent idiopathic scoliosis: a case report
    Yoji Ogura
    Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan
    BMC Musculoskelet Disord 14:132. 2013
  4. doi request reprint Modic changes in the cervical spine: prospective 10-year follow-up study in asymptomatic subjects
    M Matsumoto
    Keio University, Department of Orthopaedic Surgery, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    J Bone Joint Surg Br 94:678-83. 2012
  5. ncbi request reprint A replication study for association of 53 single nucleotide polymorphisms in a scoliosis prognostic test with progression of adolescent idiopathic scoliosis in Japanese
    Yoji Ogura
    Laboratory of Bone and Joint Diseases, Center for Integrative Medical Sciences, RIKEN, Tokyo, Japan
    Spine (Phila Pa 1976) 38:1375-9. 2013
  6. doi request reprint Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study
    Eijiro Okada
    Department of Orthopaedic Surgery, Advanced Therapy for Spine and Spinal Cord Diseases, Keio University, Shinanomachi 35, Shinjuku ku, Tokyo, Japan
    Spine (Phila Pa 1976) 34:706-12. 2009
  7. doi request reprint A replication study for association of 5 single nucleotide polymorphisms with curve progression of adolescent idiopathic scoliosis in Japanese patients
    Yoji Ogura
    Laboratory of Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Tokyo, Japan
    Spine (Phila Pa 1976) 38:571-5. 2013
  8. doi request reprint Posterior decompression surgery for extraforaminal entrapment of the fifth lumbar spinal nerve at the lumbosacral junction
    Morio Matsumoto
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku ku, Tokyo, Japan
    J Neurosurg Spine 12:72-81. 2010
  9. doi request reprint Progressive kyphoscoliosis associated with tethered cord treated by posterior vertebral column resection: a case report
    Morio Matsumoto
    Departments of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 34:E965-8. 2009
  10. doi request reprint Risk factors for closure of lamina after open-door laminoplasty
    Morio Matsumoto
    Department of Advanced Therapy for Spine and Spinal Cord Disorders, School of Medicine, Keio University, Tokyo, Japan
    J Neurosurg Spine 9:530-7. 2008

Detail Information

Publications86

  1. pmc Updates on surgical treatments for pediatric scoliosis
    Morio Matsumoto
    Department of Orthopedic Surgery, Keio University, Shinanomachi 35, Shinjuku, Tokyo, 160 8582, Japan
    J Orthop Sci 19:6-14. 2014
    ..We here review historic and recent advances in the surgical treatment of scoliosis in children, the problems associated with various techniques, and the challenges that remain to be overcome. ..
  2. doi request reprint Modic changes of the cervical spine in patients with whiplash injury: a prospective 11-year follow-up study
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Japan
    Injury 44:819-24. 2013
    ..There are few studies on Modic changes of the cervical spine in patients suffering from whiplash. This study compared Modic changes seen in whiplash patients 10 years after the injury with those observed in asymptomatic volunteers...
  3. pmc Acute respiratory failure due to hemothorax after posterior correction surgery for adolescent idiopathic scoliosis: a case report
    Yoji Ogura
    Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan
    BMC Musculoskelet Disord 14:132. 2013
    ..We here report a case of a 12-year-old girl with AIS who developed a massive postoperative hemothorax...
  4. doi request reprint Modic changes in the cervical spine: prospective 10-year follow-up study in asymptomatic subjects
    M Matsumoto
    Keio University, Department of Orthopaedic Surgery, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    J Bone Joint Surg Br 94:678-83. 2012
    ..In the cervical spine over a ten-year period, type 2 Modic changes developed most frequently. Newly developed Modic changes were significantly associated with age, gender, and pre-existing disc degeneration...
  5. ncbi request reprint A replication study for association of 53 single nucleotide polymorphisms in a scoliosis prognostic test with progression of adolescent idiopathic scoliosis in Japanese
    Yoji Ogura
    Laboratory of Bone and Joint Diseases, Center for Integrative Medical Sciences, RIKEN, Tokyo, Japan
    Spine (Phila Pa 1976) 38:1375-9. 2013
    ..A genetic association study of single nucleotide polymorphisms (SNPs) previously reported to be associated with curve progression of adolescent idiopathic scoliosis (AIS)...
  6. doi request reprint Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study
    Eijiro Okada
    Department of Orthopaedic Surgery, Advanced Therapy for Spine and Spinal Cord Diseases, Keio University, Shinanomachi 35, Shinjuku ku, Tokyo, Japan
    Spine (Phila Pa 1976) 34:706-12. 2009
    ..Prospective longitudinal study, mean follow-up period; 11.7 +/- 0.8 years was conducted from 1995 to 2007...
  7. doi request reprint A replication study for association of 5 single nucleotide polymorphisms with curve progression of adolescent idiopathic scoliosis in Japanese patients
    Yoji Ogura
    Laboratory of Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Tokyo, Japan
    Spine (Phila Pa 1976) 38:571-5. 2013
    ..A genetic association study of single nucleotide polymorphisms (SNPs) previously reported to be associated with curve progression of adolescent idiopathic scoliosis (AIS)...
  8. doi request reprint Posterior decompression surgery for extraforaminal entrapment of the fifth lumbar spinal nerve at the lumbosacral junction
    Morio Matsumoto
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku ku, Tokyo, Japan
    J Neurosurg Spine 12:72-81. 2010
    ..In this paper, the authors' goal was to elucidate the clinical features and results of decompression surgery for extraforaminal stenosis at the lumbosacral junction...
  9. doi request reprint Progressive kyphoscoliosis associated with tethered cord treated by posterior vertebral column resection: a case report
    Morio Matsumoto
    Departments of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 34:E965-8. 2009
    ..0%). CONCLUSION.: Correction of progressive kyphoscoliosis associated with a tethered cord can be achieved successfully by posterior vertebral column resection even after complicated untethering surgery...
  10. doi request reprint Risk factors for closure of lamina after open-door laminoplasty
    Morio Matsumoto
    Department of Advanced Therapy for Spine and Spinal Cord Disorders, School of Medicine, Keio University, Tokyo, Japan
    J Neurosurg Spine 9:530-7. 2008
    ..This retrospective study was conducted to evaluate the prevalence and clinical consequences of postoperative lamina closure after open-door laminoplasty and to identify the risk factors...
  11. doi request reprint Recurrence of lumbar disc herniation after microendoscopic discectomy
    Morio Matsumoto
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Neurol Surg A Cent Eur Neurosurg 74:222-7. 2013
    ..The purpose of the present study was to retrospectively investigate the recurrence rate after MED for LDH and to determine the risk factors for recurrence in patients treated by a single surgeon...
  12. doi request reprint Longitudinal magnetic resonance imaging study on whiplash injury patients: minimum 10-year follow-up
    Daisuke Ichihara
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjukuku, Tokyo, Japan
    J Orthop Sci 14:602-10. 2009
    ..We conducted a prospective long-term follow-up study to assess associations between magnetic resonance imaging (MRI) findings and changes in clinical symptoms, as well as factors relating to the prognosis of symptoms...
  13. doi request reprint Morphologic evaluation of the thoracic vertebrae for safe free-hand pedicle screw placement in adolescent idiopathic scoliosis: a CT-based anatomical study
    Guanyu Cui
    Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160 8582, Japan
    Surg Radiol Anat 34:209-16. 2012
    ..To evaluate the morphologic characteristics of the thoracic pedicle with regard to safe free-hand thoracic pedicle screw placement, based on multi-planar reconstruction CT images...
  14. pmc An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion
    Hiroya Miyamoto
    Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano machi, Shinjuku ku, Tokyo 160 8582, Japan
    J Biol Chem 287:32479-84. 2012
    ..We conclude that the STAT6-STAT1 axis regulates OC-STAMP and DC-STAMP expression and governs fusogenic mechanisms in FBGCs...
  15. doi request reprint Surgical treatment for scoliosis in patients with Shprintzen-Goldberg syndrome
    Kota Watanabe
    Department of Advanced Therapy for Spine and Spinal Cord Disorders, Keio University School of Medicine, Tokyo, Japan
    J Pediatr Orthop 31:186-93. 2011
    ..Among these skeletal findings, developmental scoliosis is recognized in half of all patients with SGS. However, no earlier reports have described the surgical treatment of scoliosis associated with SGS...
  16. ncbi request reprint Age-related changes of thoracic and cervical intervertebral discs in asymptomatic subjects
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 35:1359-64. 2010
    ..Magnetic resonance imaging (MRI) study on degeneration of the thoracic spine in asymptomatic subjects...
  17. pmc Vertebral derotation in adolescent idiopathic scoliosis causes hypokyphosis of the thoracic spine
    Kota Watanabe
    Department of Advanced Therapy for Spine and Spinal Cord Disorders, KeioUniversity, Tokyo, Japan
    BMC Musculoskelet Disord 13:99. 2012
    ..The purpose of this study was to test the hypothesis that direct vertebral derotation by pedicle screws (PS) causes hypokyphosis of the thoracic spine in adolescent idiopathic scoliosis (AIS) patients, using computer simulation...
  18. doi request reprint Prospective ten-year follow-up study comparing patients with whiplash-associated disorders and asymptomatic subjects using magnetic resonance imaging
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 35:1684-90. 2010
    ..A prospective 10-year follow-up study of patients with whiplash-associated disorders (WAD) and asymptomatic volunteers...
  19. doi request reprint Clinical significance of diffusion tensor tractography as a predictor of functional recovery after laminoplasty in patients with cervical compressive myelopathy
    Masaya Nakamura
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Neurosurg Spine 17:147-52. 2012
    ....
  20. ncbi request reprint Postoperative factors affecting neurological recovery after surgery for cervical spondylotic myelopathy
    Yuto Ogawa
    Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan
    J Neurosurg Spine 5:483-7. 2006
    ..The purpose of this study was to elucidate such postoperative factors affecting neurological recovery...
  21. doi request reprint Late instrumentation failure after total en bloc spondylectomy
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    J Neurosurg Spine 15:320-7. 2011
    ..The object of this study was to investigate failures after spinal reconstruction following total en bloc spondylectomy (TES), related factors, and sequelae arising from such failures in patients with malignant spinal tumors...
  22. doi request reprint Serum cartilage metabolites as biomarkers of degenerative lumbar scoliosis
    Naobumi Hosogane
    Orthopedic Surgery, Keio University School of Medicine, 35 Shinanomachi Shinjuku ku, Tokyo 160 8582, Japan
    J Orthop Res 30:1249-53. 2012
    ..As type II collagen is a major component of collagens in the nucleus pulposus and facet joint cartilages, its enhanced turnover may be related to the development and progression of DLS...
  23. ncbi request reprint Development of stiff shoulder in asymptomatic volunteers during ten-year follow-up in Japan
    Eijiro Okada
    Department of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
    J Back Musculoskelet Rehabil 23:69-75. 2010
    ....
  24. doi request reprint Risk factors for development of subaxial subluxations following atlantoaxial arthrodesis for atlantoaxial subluxations in rheumatoid arthritis
    Ken Ishii
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku, Tokyo, Japan
    Spine (Phila Pa 1976) 35:1551-5. 2010
    ..Retrospective radiographic/imaging study...
  25. doi request reprint Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine: a multi-institutional retrospective study
    Morio Matsumoto
    Department of Musculoskeletal Reconstruction and Regeneration Surgery, Keio University, Department of Orthopedic Surgery, Tokyo, Japan
    Spine (Phila Pa 1976) 33:1034-41. 2008
    ..Retrospective multi-institutional study..
  26. doi request reprint Complicated surgical resection of malignant tumors in the upper cervical spine after failed ion-beam radiation therapy
    Morio Matsumoto
    Departments of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo, Japan
    Spine (Phila Pa 1976) 35:E505-9. 2010
    ..Case report...
  27. ncbi request reprint Nocturnal leg cramps: a common complaint in patients with lumbar spinal canal stenosis
    Morio Matsumoto
    Department of Advanced Therapy for Spine and Spinal Cord Disease, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 34:E189-94. 2009
    ..Questionnaire survey on leg cramps for patients with lumbar spinal canal stenosis (LCS)...
  28. doi request reprint Long-term surgical outcomes of cervical dumbbell neurinomas
    Masaya Nakamura
    Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    J Orthop Sci 18:8-13. 2013
    ..Retrospective case series...
  29. pmc Conditional inactivation of Blimp1 in adult mice promotes increased bone mass
    Yoshiteru Miyauchi
    Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo 160 8582, Japan
    J Biol Chem 287:28508-17. 2012
    ..These data suggest that Blimp1 is a potential target to promote increased bone mass and prevent osteoclastogenesis...
  30. ncbi request reprint Long-term results of expansive open-door laminoplasty for ossification of the posterior longitudinal ligament of the cervical spine
    Yuto Ogawa
    Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan
    J Neurosurg Spine 1:168-74. 2004
    ..To address this issue, the authors assessed the benefits and limitations of expansive open-door laminoplasty for OPLL-related myelopathy by evaluating mid- and long-term clinical results...
  31. doi request reprint Cross-sectional area of the posterior extensor muscles of the cervical spine in whiplash injury patients versus healthy volunteers--10 year follow-up MR study
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Japan
    Injury 43:912-6. 2012
    ..The purpose of this study was to elucidate the changes in the posterior extensor muscles 10 years after whiplash injury...
  32. doi request reprint Ball tip technique for thoracic pedicle screw placement in patients with adolescent idiopathic scoliosis
    Kota Watanabe
    Department of Advanced Treatment for Spine and Spinal Cord Disorders, Keio University School of Medicine, Tokyo, Japan
    J Neurosurg Spine 13:246-52. 2010
    ..To further enhance the accuracy and safety of TPS placement, the authors developed the ball tip technique...
  33. doi request reprint Surgical treatment of spinal extradural arachnoid cysts in the thoracolumbar spine
    Haruki Funao
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Neurosurgery 71:278-84; discussion 284. 2012
    ..Because an idiopathic spinal extradural arachnoid cyst (SEAC) is rare, its optimal surgical treatment remains controversial...
  34. pmc Loss of apical vertebral derotation in adolescent idiopathic scoliosis: 2-year follow-up using multi-planar reconstruction computed tomography
    Guanyu Cui
    Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan
    Eur Spine J 21:1111-20. 2012
    ..The objective of this study was to evaluate 2 years post-surgical loss of three-dimensional correction in adolescent idiopathic scoliosis (AIS) patients using multi-planar reconstruction computed tomography (CT)...
  35. ncbi request reprint Extensive total spondylectomy for recurrent giant cell tumor in the thoracic spine. Case report
    Morio Matsumoto
    Department of Musculoskeletal Reconstruction and Regeneration Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Neurosurg Spine 6:600-5. 2007
    ..This surgical technique can be an effective option for this pathological condition, which is difficult to manage using other conventional treatment options including repeated curettage and radiotherapy...
  36. ncbi request reprint Long-term results of expansive open-door laminoplasty for cervical myelopathy--average 14-year follow-up study
    Kazuhiro Chiba
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 31:2998-3005. 2006
    ..Retrospective case series on long-term follow-up results of original expansive open-door laminoplasty for cervical myelopathy due to cervical spondylosis (CSM) and ossification of posterior longitudinal ligament (OPLL)...
  37. doi request reprint Risk factors for complications associated with growing-rod surgery for early-onset scoliosis
    Kota Watanabe
    Department of Advanced Therapy for Spine and Spinal Cord Disorders, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 38:E464-8. 2013
    ..A retrospective multicenter study...
  38. pmc Changes in the cross-sectional area of deep posterior extensor muscles of the cervical spine after anterior decompression and fusion: 10-year follow-up study using MRI
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Shinanomachi 35, Shinjuku ku, Tokyo, 160 8582, Japan
    Eur Spine J 21:304-8. 2012
    ..To evaluate changes in the transverse area of deep posterior muscles of the cervical spine 10 years after anterior cervical decompression and fusion (ACDF), in comparison with healthy volunteers...
  39. doi request reprint Impact of lamina closure on long-term outcomes of open-door laminoplasty in patients with cervical myelopathy: minimum 5-year follow-up study
    Morio Matsumoto
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 37:1288-91. 2012
    ..A prospective follow-up study...
  40. doi request reprint Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages
    Akihiro Hakozaki
    Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo 160 8582, Japan
    J Immunol 184:2442-8. 2010
    ..These observations suggest the potential involvement of ectodomain shedding in the regulation of RANK functions and may provide novel insights into the mechanisms of osteoclastogenesis...
  41. doi request reprint Remodeling of C2 facet deformity prevents recurrent subluxation in patients with chronic atlantoaxial rotatory fixation: a novel strategy for treatment of chronic atlantoaxial rotatory fixation
    Ken Ishii
    Departments of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku, Tokyo, Japan
    Spine (Phila Pa 1976) 36:E256-62. 2011
    ..A retrospective case series...
  42. doi request reprint Clinical significance and prognosis of idiopathic syringomyelia
    Masaya Nakamura
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku, Tokyo, Japan
    J Spinal Disord Tech 22:372-5. 2009
    ..Retrospective case series...
  43. doi request reprint Lack of association between adolescent idiopathic scoliosis and previously reported single nucleotide polymorphisms in MATN1, MTNR1B, TPH1, and IGF1 in a Japanese population
    Yohei Takahashi
    Laboratory of Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, 4 6 1 Sirokanedai, Minato ku, Tokyo 108 8639, Japan Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Orthop Res 29:1055-8. 2011
    ..Considering the statistical power and sample size of the present study, we concluded that these SNPs are not associated with either AIS predisposition or curve severity in Japanese...
  44. doi request reprint Risk factors for lumbar disc degeneration in high school American football players: a prospective 2-year follow-up study
    Masaki Nagashima
    Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan
    Am J Sports Med 41:2059-64. 2013
    ..Several risk factors have been proposed for intervertebral disc degeneration (DD) among adolescent athletes. However, the causes of DD are not well understood, and there have been few prospective studies evaluating DD in adolescents...
  45. ncbi request reprint Open-door laminoplasty for cervical myelopathy resulting from adjacent-segment disease in patients with previous anterior cervical decompression and fusion
    Morio Matsumoto
    Department of Uniden Musculoskeletal Reconstruction and Regeneration Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 31:1332-7. 2006
    ..This is a retrospective study of patients with cervical myelopathy resulting from adjacent-segment disease who were treated by open-door expansive laminoplasty...
  46. doi request reprint Total en bloc spondylectomy for spinal metastasis of differentiated thyroid cancers: a long-term follow-up
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    J Spinal Disord Tech 26:E137-42. 2013
    ..A retrospective case series...
  47. doi request reprint Short fusion strategy for Lenke type 1 thoracic curve using pedicle screw fixation
    Morio Matsumoto
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Spinal Disord Tech 26:93-7. 2013
    ..A retrospective case-control study..
  48. pmc Optimal treatment for spinal cord injury associated with cervical canal stenosis (OSCIS): a study protocol for a randomized controlled trial comparing early versus delayed surgery
    Hirotaka Chikuda
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Trials 14:245. 2013
    ....
  49. pmc HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis
    Yoshiteru Miyauchi
    Departments of Orthopedic Surgery, Integrated Bone Metabolism and Immunology, and Musculoskeletal Reconstruction and Regeneration Surgery, Keio Kanrinmaru Project, and Department of Dentistry and Oral Surgery, School of Medicine, Keio University, Tokyo 160 8582, Japan
    Proc Natl Acad Sci U S A 110:16568-73. 2013
    ..Oral administration of a HIF1α inhibitor protected Ovx mice from osteoclast activation and bone loss. Thus, HIF1α represents a promising therapeutic target in osteoporosis. ..
  50. doi request reprint Curve progression after decompression surgery in patients with mild degenerative scoliosis
    Naobumi Hosogane
    Orthopedic Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan
    J Neurosurg Spine 18:321-6. 2013
    ..The authors undertook this study to evaluate curve progression, risk factors for curve progression, and outcomes after decompression surgery in patients with degenerative lumbar scoliosis with minimal to moderate curvature...
  51. ncbi request reprint Long-term results after expansive open-door laminoplasty for the segmental-type of ossification of the posterior longitudinal ligament of the cervical spine: a comparison with nonsegmental-type lesions
    Yuto Ogawa
    Department of Orthopedic Surgery, School of Medicine Keio University, Shinjuku, Tokyo, Japan
    J Neurosurg Spine 3:198-204. 2005
    ..To clarify this issue, the long-term results after surgical treatment of segmental-type OPLL were compared with those of other types...
  52. doi request reprint Wedging of vertebral bodies at the thoracolumbar junction in asymptomatic healthy subjects on magnetic resonance imaging
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Surg Radiol Anat 33:223-8. 2011
    ..The purpose of this study was to elucidate the normative value of vertebral wedging at the thoracolumbar junction in asymptomatic healthy subjects for differential diagnosis of vertebral compression fractures using MRI...
  53. pmc Cross-sectional area of posterior extensor muscles of the cervical spine in asymptomatic subjects: a 10-year longitudinal magnetic resonance imaging study
    Eijiro Okada
    Department of Orthopaedic Surgery, Keio University, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    Eur Spine J 20:1567-73. 2011
    ..Development of shoulder stiffness during follow-up was significantly negatively correlated with a change in the cross-sectional area of the deep extensor muscles...
  54. doi request reprint Anterior cervical decompression and fusion accelerates adjacent segment degeneration: comparison with asymptomatic volunteers in a ten-year magnetic resonance imaging follow-up study
    Morio Matsumoto
    Departments of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 35:36-43. 2010
    ..Prospective 10-year follow-up magnetic resonance imaging (MRI) study of patients who underwent anterior cervical decompression and fusion (ACDF) and healthy control subjects...
  55. doi request reprint Central neuropathic pain after surgical resection in patients with spinal intramedullary tumor
    Masaya Nakamura
    Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    J Orthop Sci 17:352-7. 2012
    ..Retrospective case series...
  56. ncbi request reprint Inhibition of STAT1 accelerates bone fracture healing
    Kosuke Tajima
    Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    J Orthop Res 28:937-41. 2010
    ..These results reveal previously unknown functions of STAT1 in skeletal homeostasis and may have important clinical implications for the treatment of skeletal bone fracture...
  57. doi request reprint Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis
    Hiroko Hoshi
    Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano machi, Shinjuku ku, Tokyo, Japan
    J Bone Miner Res 27:2015-23. 2012
    ..These results provide new insight into regulation of osteoporosis in a subset of individuals with ALDH2*2 and in alcoholic patients and suggest a novel strategy to promote bone formation in such osteopenic diseases...
  58. pmc Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3
    Atsushi Miyake
    Laboratory for Bone and Joint Diseases, RIKEN Center for Integrative Medical Science, Tokyo, Japan Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    PLoS ONE 8:e72802. 2013
    ..43 × 10(-12), OR = 2.21). rs12946942 is on chromosome 17q24.3 near the genes SOX9 and KCNJ2, which when mutated cause scoliosis phenotypes. Our findings will offer new insight into the etiology and progression of AIS...
  59. pmc Tandem age-related lumbar and cervical intervertebral disc changes in asymptomatic subjects
    Morio Matsumoto
    Department of Orthopaedic Surgery, Keio University, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    Eur Spine J 22:708-13. 2013
    ..To investigate the frequency of tandem lumbar and cervical intervertebral disc degeneration in asymptomatic subjects...
  60. pmc Comparative study of spinopelvic sagittal alignment between patients with and without degenerative spondylolisthesis
    Haruki Funao
    Department of Orthopeadic Surgery, School of Medicine, Keio University, 35 Shinjuku, 160 8582, Tokyo, Japan
    Eur Spine J 21:2181-7. 2012
    ..The objectives of this study were to compare differences in spinopelvic sagittal alignment between patients with or without DS and to elucidate factors related to spinopelvic sagittal alignment...
  61. pmc Increase in spinal longitudinal length by correction surgery for adolescent idiopathic scoliosis
    Kota Watanabe
    Department of Advanced Therapy for Spine and Spinal Cord Disorders, Keio University School of Medicine, Tokyo, Japan
    Eur Spine J 21:1920-5. 2012
    ..The purpose of this study was to evaluate the correlation between curve correction and increased spinal longitudinal length by corrective surgery for AIS...
  62. ncbi request reprint Surgical correction of severe cervical kyphosis in patients with neurofibromatosis Type 1
    Soya Kawabata
    Departments of Orthopaedic Surgery, Keio University, Tokyo, Japan
    J Neurosurg Spine 18:274-9. 2013
    ....
  63. doi request reprint Cordotomy for patients with thoracic malignant astrocytoma
    Masaya Nakamura
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Shinjuku, Tokyo, Japan
    J Neurosurg Spine 13:418-23. 2010
    ..In this study the authors investigated the surgical outcomes of cordotomy in patients with thoracic malignant astrocytomas to determine the effectiveness of this procedure...
  64. pmc Does the sagittal alignment of the cervical spine have an impact on disk degeneration? Minimum 10-year follow-up of asymptomatic volunteers
    Eijiro Okada
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Eur Spine J 18:1644-51. 2009
    ..Sagittal alignment of the cervical spine had some impact on the progression of degenerative changes of the cervical spine with aging; however, it had no correlation with the occurrence of future clinical symptoms...
  65. doi request reprint Long-term surgical outcomes for myxopapillary ependymomas of the cauda equina
    Masaya Nakamura
    Department of Orthopedic Surgery, School of Medicine, Keio University, Shinjuku, Tokyo, Japan
    Spine (Phila Pa 1976) 34:E756-60. 2009
    ..Retrospective case series...
  66. doi request reprint Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis
    Masaki Yoda
    Department of Anti aging Orthopedic Research, School of Medicine, Keio University, Tokyo, Japan
    Blood 118:6939-42. 2011
    ..Taken together, the present findings reveal previously undescribed nonredundant roles of cell-autonomous and non-cell-autonomous ADAM10 activity in the maintenance of hematopoiesis...
  67. ncbi request reprint Novel apatite fiber scaffolds can promote three-dimensional proliferation of osteoblasts in rodent bone regeneration models
    Hikaru Morisue
    Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    J Biomed Mater Res A 90:811-8. 2009
    ..In both in vitro and in vivo environments, the more porous AFS was more advantageous in cell proliferation, cell adhesion, proliferating capacity, robust cell differentiation, ultimately inducing bone ingrowth inside the scaffolds...
  68. pmc The IRE1α-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis
    Takahide Tohmonda
    Department of Anti aging Orthopedic Research, Keio University, School of Medicine, Tokyo 160 8582, Japan
    J Biol Chem 288:1691-5. 2013
    ..Thus, the present study reveals potential involvement of the IRE1α-XBP1 pathway in PTH-induced osteoclastogenesis through the regulation of PTH1R expression...
  69. pmc Disc degeneration of cervical spine on MRI in patients with lumbar disc herniation: comparison study with asymptomatic volunteers
    Eijiro Okada
    Department of Orthopaedic Surgery, Keio University, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    Eur Spine J 20:585-91. 2011
    ..The result of this study suggests that disc degeneration appears to be a systemic phenomenon...
  70. doi request reprint A rare case of spinal dumbbell tanycytic ependymoma
    Hiroko Ishihama
    Department of Orthopedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 36:E612-4. 2011
    ..Case report...
  71. pmc Long-term surgical outcomes of idiopathic spinal cord herniation
    Masaya Nakamura
    Department of Orthopedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo, 160 8582, Japan
    J Orthop Sci 16:347-51. 2011
    ..The purpose of this study is to determine the long-term effectiveness of this procedure...
  72. pmc A functional polymorphism in COL11A1, which encodes the alpha 1 chain of type XI collagen, is associated with susceptibility to lumbar disc herniation
    Futoshi Mio
    Laboratory for Bone and Joint Diseases, School of Medicine, Keio University, Tokyo
    Am J Hum Genet 81:1271-7. 2007
    ..These observations indicate that type XI collagen is critical for IVD metabolism and that its decrease is related to LDH...
  73. ncbi request reprint Pathognomonic radiological signs for predicting prognosis in patients with chronic atlantoaxial rotatory fixation
    Ken Ishii
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Neurosurg Spine 5:385-91. 2006
    ..The authors conducted a study to assess the correlation between radiological features and clinical courses in patients with chronic atlantoaxial rotatory fixation (AARF) and to determine diagnostic imaging signs for predicting prognosis...
  74. doi request reprint Long-term surgical outcomes of spinal meningiomas
    Masaya Nakamura
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 37:E617-23. 2012
    ..Retrospective case series...
  75. doi request reprint Sterility of posterior elements of the spine in posterior correction surgery
    Yuta Shiono
    Department of Orthopaedic Surgery, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 37:523-6. 2012
    ..Prospective clinical series...
  76. pmc Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivo
    Masaki Yoda
    Anti aging Orthopedic Research, School of Medicine, Keio University, Tokyo, Japan
    PLoS ONE 8:e54412. 2013
    ..These observations indicate that TACE activity is not necessarily dependent on transcriptional regulation and that excess TACE does not necessarily result in aberrant proteolytic activity in vivo...
  77. ncbi request reprint Posterior osteotomy and instrumentation for thoracolumbar kyphosis in patients with achondroplasia
    Xin Qi
    Department of Musculoskeletal Reconstruction and Regeneration Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 31:E606-10. 2006
    ..A retrospective case series of surgically treated achondroplastic patients with severe thoracolumbar kyphosis...
  78. doi request reprint Management of chronic atlantoaxial rotatory fixation
    Ken Ishii
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    Spine (Phila Pa 1976) 37:E278-85. 2012
    ..Retrospective case series of chronic atlantoaxial rotatory fixation (AARF) treated by a novel closed reduction method (remodeling therapy) and review of the literature...
  79. pmc Morphometric analysis of the lumbar intervertebral foramen in patients with degenerative lumbar scoliosis by multidetector-row computed tomography
    Yasuhito Kaneko
    Department of Orthopaedic Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    Eur Spine J 21:2594-602. 2012
    ..Here, we used multidetector-row computed tomography (MDCT) to measure the morphology of the foramina in three dimensions, which allowed us to elucidate the relationships between foraminal morphology and segmental deformities in DLS...
  80. doi request reprint Radiographic predictors of residual low back pain after laminectomy for lumbar spinal canal stenosis: minimum 5-year follow-up
    Yingpeng Xia
    Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan
    J Spinal Disord Tech 21:153-8. 2008
    ..Retrospective study of patients who underwent laminectomy for unification...
  81. doi request reprint Matrix metalloproteinase 13 in the ligamentum flavum from lumbar spinal canal stenosis patients with and without diabetes mellitus
    Guanyu Cui
    Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160 8582, Japan
    J Orthop Sci 16:785-90. 2011
    ....
  82. doi request reprint Long-term impact of atlantoaxial arthrodesis on the pediatric cervical spine
    Masayuki Ishikawa
    Department of Orthopaedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    J Orthop Sci 14:274-8. 2009
    ..This study was conducted to elucidate radiographically the long-term impact of atlantoaxial arthrodesis on the pediatric cervical spine...
  83. doi request reprint Mechanism of osteoporosis in adolescent idiopathic scoliosis: experimental scoliosis in pinealectomized chickens
    Hitoshi Kono
    Department of Orthopaedic Surgery School of Medicine, Keio University, Tokyo, Japan
    J Pineal Res 51:387-93. 2011
    ..The restoration of melatonin prevented the development of scoliosis and osteoporosis, indicating that melatonin levels may be crucial to the development of deformity and osteoporosis in AIS...
  84. ncbi request reprint Comparative assessment of pedicle morphology of the lumbar spine in various degenerative diseases
    Kenya Nojiri
    Department of Orthopedic Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    Surg Radiol Anat 27:317-21. 2005
    ....
  85. doi request reprint Osteoclast stimulatory transmembrane protein and dendritic cell–specific transmembrane protein cooperatively modulate cell–cell fusion to form osteoclasts and foreign body giant cells
    Hiroya Miyamoto
    Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano machi, Shinjuku ku, Tokyo, Japan
    J Bone Miner Res 27:1289-97. 2012
    ..Thus, fusogenic mechanisms in macrophage-lineage cells are regulated via OC-STAMP and DC-STAMP...
  86. doi request reprint Outcomes of fusion surgery for ossification of the posterior longitudinal ligament of the thoracic spine: a multicenter retrospective survey: clinical article
    Morio Matsumoto
    Department of Orthopedic Surgery, Keio University, Japan
    J Neurosurg Spine 15:380-5. 2011
    ..The aim of this study was to evaluate the outcomes of fusion surgery in patients with ossification of the posterior longitudinal ligament in the thoracic spine (T-OPLL) and to identify factors significantly related to surgical outcomes...