Research Topics
Genomes and GenesSpecies | M AkiyamaSummaryAffiliation: Keio University Country: Japan Publications
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Detail Information
Publications
Regional difference in expression of characteristic abnormality of harlequin ichthyosis in affected fetusesM Akiyama
Department of Biological Structure, Medicine Dermatology, University of Washington School of Medicine, Seattle, USA
Prenat Diagn 18:425-36. 1998..In addition, the prenatal diagnosis or prenatal exclusion of HI is thought to be possible from whichever site of the fetal body the skin biopsy is taken in the late second trimester of the fetal period...- Prenatal diagnosis of harlequin ichthyosis by the examination of keratinized hair canals and amniotic fluid cells at 19 weeks' estimated gestational ageM Akiyama
Division of Dermatology, Kitasato Institute Hospital, Tokyo, Japan
Prenat Diagn 19:167-71. 1999.... - The pathogenesis of severe congenital ichthyosis of the neonateM Akiyama
Division of Dermatology, Kitasato Institute Hospital, Tokyo, Japan
J Dermatol Sci 21:96-104. 1999..Mutations within the rod domain, not in the beginning or the end of the rod domain, of keratin 10 were reported in annular epidermolytic ichthyosis (AEI), the distinct subtype of bullous congenital ichthyosiform erythroderma... - Precise ultrastructural localization of in vivo deposited IgG antibodies in fresh perilesional skin of patients with bullous pemphigoidM Sato
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
Br J Dermatol 138:965-71. 1998.... - MDM2 protein overexpression inhibits apoptosis of TF-1 granulocyte-macrophage colony-stimulating factor-dependent acute myeloblastic leukemia cellsM Urashima
Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan
Blood 92:959-67. 1998..These results suggest that GM-CSF-independent growth of AML cells is associated with overexpression of MDM2 protein and related modulation of p53 expression... - Abnormalities of basal cell keratin in epidermolysis bullosa simplex do not affect the expression patterns of suprabasal keratins and cornified cell envelope proteinsY Sasaki
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
Arch Dermatol Res 290:591-7. 1998..Thus, the abnormality in basal cell keratins in patients with EBS did not appear to alter the patterns of expression of the keratins and CCE precursor proteins... - Epimorphin expression during human foetal hair follicle developmentM Akiyama
Division of Dermatology, Kitasato Institute Hospital, Tokyo 108 8642, Japan
Br J Dermatol 141:447-52. 1999..This suggests that epimorphin may have an important part in induction of morphogenesis during human foetal hair follicle development... - Dissociation of intra- and extracellular domains of desmosomal cadherins and E-cadherin in Hailey-Hailey disease and Darier's diseaseM Hakuno
Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
Br J Dermatol 142:702-11. 2000..This common phenomenon in HHD and DD might be closely related to the pathophysiological mechanisms in both conditions... - Talc and amosite/crocidolite preferentially deposited in the lungs of nonoccupational female lung cancer cases in urban areas of JapanH Yamada
Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
Environ Health Perspect 105:504-8. 1997.... - Medical Internet exchange project in JapanH Mizushima
National Cancer Center Research Institute, Tokyo, Japan
Stud Health Technol Inform 52:417-9. 1998..For this purpose, we are currently asking other countries to form a structure similar to MDX-Japan. The concept, hardware system, software system, firewall configuration, and routing policy will be also discussed... - Upregulation of P-cadherin expression in the lesional skin of pemphigus, Hailey-Hailey disease and Darier's diseaseM Hakuno
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
J Cutan Pathol 28:277-81. 2001..The purpose of the present study was to determine whether altered P-cadherin expression is present in these diseases... - The extracellular domain of BPAG2 has a loop structure in the carboxy terminal flexible tail in vivoS Nonaka
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
J Invest Dermatol 115:889-92. 2000..This unique structure of the antigen is thought to contribute to dermo- epidermal adhesion by intertwining with other basement membrane components... - Interleukin-8 and monocyte chemotactic protein-1 production by a human glioblastoma cell line, T98G in coculture with monocytes: involvement of monocyte-derived interleukin-1alphaT Kasahara
Department of Biochemistry, Kyoritsu College of Pharmacy, Tokyo, Japan
Eur Cytokine Netw 9:47-55. 1998..e., juxtacrine interaction in unfixed conditions... - An oral CD40 ligand gene therapy against lymphoma using attenuated Salmonella typhimuriumM Urashima
Department of Pediatrics, The Jikei University School of Medicine, Tokyo, Japan
Blood 95:1258-63. 2000..These results have the potential to be a simple, effective, and above all, safe immune-gene therapy against BCL. (Blood. 2000;95:1258-1263).. - Drug eruptions to contrast media in JapanT Nakada
Department of Dermatology, Showa University School of Medicine, Hatanodai, Tokyo, Japan
Clin Exp Dermatol 31:361-4. 2006..In Japan, drug eruptions to nonionic iodinated contrast media have been reported since the products appeared on the market in 1986... - Revascularization by percutaneous transluminal angioplasty improved abruptly deteriorated ischaemic symptoms in cutaneous polyarteritis nodosaS Osada
Department of Dermatology, Nippon Medical School, Bunkyo ku, Tokyo, Japan
Clin Exp Dermatol 36:502-5. 2011..The occluded segment was revascularized by percutaneous transluminal angioplasty, resulting in a dramatic improvement in the ischaemic symptoms... - Migration of the Japanese healthcare enterprise from a financial to integrated management: strategy and architectureM Akiyama
Department of Medical Informatics, International Medical Center of Japan, Tokyo, 162 8655, Japan
Stud Health Technol Inform 84:715-8. 2001..Finally, it reduces costs, raises efficiency, increases the quality of patient care, and ultimately saves lives. Now, we are going to integrate all remaining hospital departments, and ultimately, all hospital functions... - Restoration of p16INK4A protein induces myogenic differentiation in RD rhabdomyosarcoma cellsM Urashima
Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan
Br J Cancer 79:1032-6. 1999..These suggest that deletion of p16 gene may not only facilitate growth but also inhibit the myogenic differentiation of RD RMS cells... - A novel asparagine-->aspartic acid mutation in the rod 1A domain in keratin 2e in a Japanese family with ichthyosis bullosa of SiemensY Takizawa
Department of Dermatology, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
J Invest Dermatol 114:193-5. 2000..Our data indicate aspartic acid substitution in codon 192 in the 1A helix initiation site is deleterious to keratin filament network integrity and leads to ichthyosis bullosa of Siemens phenotype... - Genetic instability in intestinal metaplasia is a frequent event leading to well-differentiated early adenocarcinoma of the stomachK Kobayashi
Department of Surgery II, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, 105 8461, Tokyo, Japan
Eur J Cancer 36:1113-9. 2000..These findings suggest that metaplasia and well-differentiated adenocarcinoma in the stomach may have the same molecular backgrounds, and that these two lesions may be chronologically connected... - Ichthyosis bullosa of Siemens: its correct diagnosis facilitated by molecular genetic testingM Akiyama
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
Br J Dermatol 152:1353-6. 2005..The present results indicate that IBS is not such a rare entity as was previously thought, and accurate diagnosis is now available by mutation analysis... - An outbreak of food poisoning due to egg yolk reaction-negative Staphylococcus aureusN Miwa
Shizuoka Institute of Environment and Hygiene, Japan
Int J Food Microbiol 64:361-6. 2001..aureus. The present outbreak suggested that EY reaction-negative isolates should be subjected to further analysis to detect the causative agents of staphylococcal food poisoning... - [Epidemiological analysis of influenza B virus belonging to B/Victoria/2/87 lineage isolated in off-season of 1998 and late epidemic season in Shizuoka Prefecture]K Sahara
Department of Microbiology, Shizuoka Institute of Environment and Hygiene
Kansenshogaku Zasshi 74:481-5. 2000..This indicates that the herald viruses are not always the parental viruses for the following influenza season... - A novel ABCA12 mutation 3270delT causes harlequin ichthyosisM Akiyama
, , Freiburg, Germany
Br J Dermatol 155:1064-6. 2006 - A novel mutation in the VDR gene in hereditary vitamin D-resistant ricketsK Arita
Genetic Skin Disease Group, St John's Institute of Dermatology, Division of Genetics and Molecular Medicine, The Guy's, King's College and St Thomas' School of Medicine, London, UK
Br J Dermatol 158:168-71. 2008 - Risk management and measuring productivity with POAS--Point of Act System--a medical information system as ERP (Enterprise Resource Planning) for hospital managementM Akiyama
Sloan School of Management, Massachusetts Institute of Technology, Cambridge, MA, USA
Methods Inf Med 46:686-93. 2007.... - Detection of 1733insC mutations in an Asian family with Birt-Hogg-Dubé syndromeH Kawasaki
Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo 060-8638, Japan
Br J Dermatol 152:142-5. 2005..CONCLUSIONS: This study is the first to find the same hot-spot 1733insC mutation in Asian kindred. The mutations in this polycytosine tract may have a wide, global distribution despite their arising from a different ethnic background...