Koichi Aiura

Summary

Affiliation: Keio University
Country: Japan

Publications

  1. ncbi request reprint Duodenal gastrointestinal stromal tumor adjacent to the minor papilla with concomitant pancreatic divisum
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku ku, Tokyo 160 8582, Japan
    Dig Dis Sci 52:3191-8. 2007
  2. ncbi request reprint Successful pancreatectomy with en-bloc resection of the celiac artery and portal vein for pancreatic endocrine carcinoma
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Hepatogastroenterology 54:1269-71. 2007
  3. doi request reprint Surgical technique for complete resection of the extrahepatic portion of the common bile duct and the ampulla of Vater for tumors of the ampulla of Vater
    Koichi Aiura
    Department of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    J Hepatobiliary Pancreat Sci 18:276-81. 2011
  4. pmc Current status of endoscopic papillary balloon dilation for the treatment of bile duct stones
    Koichi Aiura
    Center for Diagnostic and Therapeutic Endoscopy, Department of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo, 160 8582, Japan
    J Hepatobiliary Pancreat Sci 18:339-45. 2011
  5. doi request reprint Beneficial effects of 5-Fluorouracil and heparin-based portal infusion chemotherapy combined with mitomycin C and cisplatin after curative resection of pancreatic cancer
    Koichi Aiura
    Department of Surgery at Keio University School of Medicine, Tokyo, Japan
    Pancreatology 10:250-8. 2010
  6. pmc Proposed indications for limited resection of early ampulla of Vater carcinoma: clinico-histopathological criteria to confirm cure
    Koichi Aiura
    Department of Surgery, Kawasaki Municipal Hospital, Shinkawadori 12, Kawasaki ku, Kawasaki, Kanagawa, 210 0013, Japan
    J Hepatobiliary Pancreat Sci 19:707-16. 2012
  7. doi request reprint Autofluorescence videoendoscopy system using the SAFE-3000 for assessing superficial gastric neoplasia
    Hiroyuki Imaeda
    Center for Diagnostic and Therapeutic Endoscopy, School of Medicine, Keio University, Tokyo, Japan
    J Gastroenterol Hepatol 25:706-11. 2010
  8. ncbi request reprint Retrospective analysis of outcome in 63 gallbladder carcinoma patients after radical resection
    Hiroshi Yagi
    Department of Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    J Hepatobiliary Pancreat Surg 13:530-6. 2006
  9. ncbi request reprint Primary undifferentiated spindle-cell carcinoma of the gallbladder presenting as a liver tumor
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
    J Gastroenterol 40:993-8. 2005
  10. doi request reprint Recurrent pancreatitis caused by ampullary carcinoma and minor papilla adenoma in familial polyposis: report of a case
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Surg Today 38:440-4. 2008

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Duodenal gastrointestinal stromal tumor adjacent to the minor papilla with concomitant pancreatic divisum
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku ku, Tokyo 160 8582, Japan
    Dig Dis Sci 52:3191-8. 2007
  2. ncbi request reprint Successful pancreatectomy with en-bloc resection of the celiac artery and portal vein for pancreatic endocrine carcinoma
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Hepatogastroenterology 54:1269-71. 2007
    ....
  3. doi request reprint Surgical technique for complete resection of the extrahepatic portion of the common bile duct and the ampulla of Vater for tumors of the ampulla of Vater
    Koichi Aiura
    Department of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    J Hepatobiliary Pancreat Sci 18:276-81. 2011
    ..Local resection can be the procedure of choice in selected ampullary lesions for high-risk patients...
  4. pmc Current status of endoscopic papillary balloon dilation for the treatment of bile duct stones
    Koichi Aiura
    Center for Diagnostic and Therapeutic Endoscopy, Department of Surgery, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo, 160 8582, Japan
    J Hepatobiliary Pancreat Sci 18:339-45. 2011
    ..Therefore, the aim of this review is to re-evaluate the status of EPBD for the treatment of common bile duct stones...
  5. doi request reprint Beneficial effects of 5-Fluorouracil and heparin-based portal infusion chemotherapy combined with mitomycin C and cisplatin after curative resection of pancreatic cancer
    Koichi Aiura
    Department of Surgery at Keio University School of Medicine, Tokyo, Japan
    Pancreatology 10:250-8. 2010
    ..The goal was to determine if this treatment prevented liver metastasis and improved survival for patients with potentially curative resection of pancreatic cancer...
  6. pmc Proposed indications for limited resection of early ampulla of Vater carcinoma: clinico-histopathological criteria to confirm cure
    Koichi Aiura
    Department of Surgery, Kawasaki Municipal Hospital, Shinkawadori 12, Kawasaki ku, Kawasaki, Kanagawa, 210 0013, Japan
    J Hepatobiliary Pancreat Sci 19:707-16. 2012
    ..We aimed to define indications for limited resection of early ampulla of Vater carcinoma with curative intent through detailed preoperative examinations and histopathological evaluations...
  7. doi request reprint Autofluorescence videoendoscopy system using the SAFE-3000 for assessing superficial gastric neoplasia
    Hiroyuki Imaeda
    Center for Diagnostic and Therapeutic Endoscopy, School of Medicine, Keio University, Tokyo, Japan
    J Gastroenterol Hepatol 25:706-11. 2010
    ....
  8. ncbi request reprint Retrospective analysis of outcome in 63 gallbladder carcinoma patients after radical resection
    Hiroshi Yagi
    Department of Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    J Hepatobiliary Pancreat Surg 13:530-6. 2006
    ..The aim of this study was to evaluate factors influencing outcome in gallbladder carcinoma after radical resection, in order to identify those patients benefiting from radical surgery...
  9. ncbi request reprint Primary undifferentiated spindle-cell carcinoma of the gallbladder presenting as a liver tumor
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
    J Gastroenterol 40:993-8. 2005
    ..Further studies are needed to better understand the characteristics of this deadly tumor, and to establish an effective therapy for it...
  10. doi request reprint Recurrent pancreatitis caused by ampullary carcinoma and minor papilla adenoma in familial polyposis: report of a case
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Surg Today 38:440-4. 2008
    ..The patient has no evidence of disease and has experienced no pancreatitis in 3 years of follow-up...
  11. ncbi request reprint Can endoscopic ultrasonography differentiate nonneoplastic from neoplastic gallbladder polyps?
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Dig Dis Sci 51:416-21. 2006
    ..However, we should caution that these findings can also occur in neoplastic polyps when they contain a concomitant nonneoplastic component (cholesterosis or proliferated Rokitansky-Aschoff sinuses)...
  12. ncbi request reprint Clinicopathological features and surgical outcome of isolated metastasis of renal cell carcinoma
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    Hepatogastroenterology 54:1836-40. 2007
    ..The benefit of pancreatic resection for metastatic renal cell carcinoma (RCC) is poorly defined. Here, we investigate the clinicopathological features and surgical outcome of patients with pancreatic metastasis from RCC...
  13. ncbi request reprint Endoscopic ultrasonography of nonfunctioning pancreatic islet cell tumors with histologic correlation
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Hepatogastroenterology 51:1590-4. 2004
    ..The present study aimed to evaluate endoscopic ultrasonography (EUS) features of benign and malignant tumors with histologic correlation...
  14. ncbi request reprint Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Hepatogastroenterology 52:603-5. 2005
    ....
  15. doi request reprint Combined effect of dehydroxymethylepoxyquinomicin and gemcitabine in a mouse model of liver metastasis of pancreatic cancer
    Keiichi Suzuki
    Department of Surgery, Kitasato Institute Hospital, 5 9 1 Shirogane, Minato ku, Tokyo 108 8642, Japan
    Clin Exp Metastasis 30:381-92. 2013
    ..Combination therapy with DHMEQ and GEM also showed potential efficacy. DHMEQ is a promising drug for the treatment of advanced pancreatic cancer...
  16. ncbi request reprint Signet-ring cell carcinoma of the ampulla of Vater: report of a case
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, Japan
    Surg Today 37:1110-4. 2007
    ..Due to the lack of sufficient evidence, additional reports are warranted to determine whether SRCC also portends a poor prognosis in patients with ampullary cancer...
  17. ncbi request reprint Intrahepatic cholangiocarcinoma with old infestation of Schistosoma japonicum: report of a case
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    Surg Today 37:905-9. 2007
    ..More data are necessary to evaluate the differences in clinicopathological findings between cholangiocarcinoma concomitant with S. japonicum and the usual type of cholangiocarcinoma...
  18. ncbi request reprint Intrahepatic cholangiocarcinoma arising 33 years after excision of a choledochal cyst: report of a case
    Ryo Nishiyama
    Department of Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan
    Int Surg 96:320-5. 2011
    ..This suggests that the cancer development could be related to intrahepatic cholestasis. Patients with choledochal cyst may have to be carefully followed up for more than 30 years even after diversion surgery...
  19. ncbi request reprint Anti-tumor effect in an in vivo model by human-derived pancreatic RNase with basic fibroblast growth factor insertional fusion protein through antiangiogenic properties
    Hiroshi Yagi
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Cancer Sci 97:1315-20. 2006
    ..These findings identify CL-RFN89 as a potent systemic inhibitor of tumor growth as a result of its antiangiogenic properties. This protein appears to be a new systemic antitumor agent...
  20. ncbi request reprint Gallbladder carcinoma with osteoclast-like giant cells
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    J Gastroenterol 41:83-7. 2006
    ....
  21. ncbi request reprint Long-term survival of patients with gallbladder cancer detected during or after laparoscopic cholecystectomy
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, 160 8582 Shinjyuku ku, Tokyo, Japan
    World J Surg 29:1106-9, discussion 1110. 2005
    ..We consider that an intensive preoperative work-up and meticulous inspection of the opened gallbladder should be mandatory to detect gallbladder cancer in patients who undergo LC. At present, this is not routinely practiced...
  22. ncbi request reprint Left trisegmentectomy and combined resection of the inferior vena cava, without reconstruction, for giant cystadenocarcinoma of the liver
    Ryohei Miyata
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
    J Hepatobiliary Pancreat Surg 12:272-6. 2005
    ..The confluence of the right inferior vein and the IVC could have been deformed, causing outflow blockade. The intrinsic shunt was not good enough to act as the drainage pathway, and IVC reconstruction may have been needed...
  23. doi request reprint Solitary cell infiltration is a novel indicator of poor prognosis and epithelial-mesenchymal transition in pancreatic cancer
    Yohei Masugi
    Department of Pathology, Keio University School of Medicine, Tokyo 160 8582, Japan
    Hum Pathol 41:1061-8. 2010
    ..In conclusion, solitary cell infiltration is a significant prognostic indicator and serves as a morphological clue to epithelial-mesenchymal transition in pancreatic cancer...
  24. ncbi request reprint Establishment of combined immuno-chemotherapy with systemically administered gemcitabine and intra-portal administration of interleukin-2 in murine models of liver metastases of pancreatic cancer
    Yasuhiro Ito
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Int J Oncol 33:49-58. 2008
    ....
  25. pmc Concomitant pancreatic endocrine neoplasm and intraductal papillary mucinous neoplasm: a case report and literature review
    Yoshie Kadota
    Department of Surgery, School of Medicine, Shinjuku, Tokyo, Japan
    World J Surg Oncol 11:75. 2013
    ..Herein, we review the case and relevant studies in the literature and discuss issues related to the synchronous occurrence of the relatively rare tumors, PEN and IPMN...
  26. doi request reprint Novel technique of endoscopic submucosal dissection using an external grasping forceps for superficial gastric neoplasia
    Hiroyuki Imaeda
    Center for Diagnostic and Therapeutic Endoscopy, Keio University Hospital, Shinjuku ku, Tokyo, Japan
    Dig Endosc 21:122-7. 2009
    ..Bleeding after ESD occurred in 10 patients (3.8%) and perforation occurred in one patient (0.4%). The endoscopic submucosal dissection using an external grasping forceps for superficial gastric neoplasia is efficacious and safe...
  27. ncbi request reprint Platelets counts closely correlate with the disease-free survival interval of pancreatic cancer patients
    Keiichi Suzuki
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Hepatogastroenterology 51:847-53. 2004
    ..We investigated the relationship between preoperative platelets count and the outcome of pancreatic cancer patients...
  28. ncbi request reprint Comparison of K-ras point mutation distributions in intraductal papillary-mucinous tumors and ductal adenocarcinoma of the pancreas
    Minoru Kitago
    Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
    Int J Cancer 110:177-82. 2004
    ..IPMT patients exhibit a remarkably genetic heterogeneity in main tumor and have good prognosis...
  29. ncbi request reprint A novel Von Hippel-Lindau case with germline mutation at codon 167 (CGG to TGG) having endocrine microadenomatosis of the pancreas
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    Dig Dis Sci 52:3145-8. 2007
  30. ncbi request reprint Balloon-catheter-assisted endoscopic snare papillectomy for benign tumors of the major duodenal papilla
    Koichi Aiura
    Center for Diagnostic and Therapeutic Endoscopy, Keio University Hospital, Tokyo, Japan
    Gastrointest Endosc 57:743-7. 2003
    ..An endoscopic snare papillectomy technique was devised using a balloon catheter inserted into the common bile duct to more efficiently resect papillary tumors en bloc...
  31. ncbi request reprint The influence of platelets on the promotion of invasion by tumor cells and inhibition by antiplatelet agents
    Keiichi Suzuki
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Pancreas 29:132-40. 2004
    ..Using a chemoinvasion assay, we show that platelets promote invasiveness of 5 pancreatic adenocarcinoma cell lines...
  32. doi request reprint Synuclein-gamma is closely involved in perineural invasion and distant metastasis in mouse models and is a novel prognostic factor in pancreatic cancer
    Taizo Hibi
    Department of Pathology, Keio University School of Medicine, Tokyo, Japan
    Clin Cancer Res 15:2864-71. 2009
    ..We previously reported a novel perineural invasion model and distinguished high- and low-perineural invasion groups in pancreatic cancer cell lines. This study aimed to elucidate the molecular mechanism of perineural invasion...
  33. ncbi request reprint Pseudoaneurysm of the cystic artery secondary to cholecystitis as a cause of hemobilia: report of a case
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    Surg Today 37:412-7. 2007
    ..Once the pseudoaneurysm is confirmed, its embolization before a cholecystectomy (which can be attempted laparoscopically) may be useful to ensure the safety of the patient...
  34. ncbi request reprint Gallstone disease after extended (D2) lymph node dissection for gastric cancer
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, 160 8582 Shinjyuku ku, Tokyo, Japan
    World J Surg 29:182-6. 2005
    ..A closer follow-up should be mandatory for gallstone disease after D2 dissection, but further studies are needed before generalizations can be made...
  35. ncbi request reprint Intraductal growth of a nonfunctioning endocrine tumor of the pancreas
    Tomotaka Akatsu
    Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku ku, 160 8582, Tokyo, Japan
    J Gastroenterol 39:584-8. 2004
    ..It is speculated that the tumor originated from precursor cells of the pancreatic duct or islet cells adjacent to the MPD and slowly proliferated within the lumen of the MPD...
  36. doi request reprint Surgery versus radiochemotherapy for resectable locally invasive pancreatic cancer: final results of a randomized multi-institutional trial
    Ryuichiro Doi
    Department of Surgery, Kyoto University, 54 Shogoinkawaracho, Sakyo ku, Kyoto, 606 8507, Japan
    Surg Today 38:1021-8. 2008
    ..The preliminary results of our multi-institutional randomized controlled trial revealed better survival after surgery than after radiochemotherapy. We report the final results of this study after 5 years of follow-up...
  37. ncbi request reprint Anti-angiogenic effect of an insertional fusion protein of human basic fibroblast growth factor and ribonuclease-1
    Tetsu Hayashida
    Department of Surgery, School of Medicine, Keio University, Shinanomachi 35, Shinjyuku ku, Tokyo 160 8582, Japan
    Protein Eng Des Sel 18:321-7. 2005
    ..These results demonstrated that CL-RFN89 inhibits angiogenesis in vitro and in vivo and that it can be expected to be a potent antiangiogenic agent...
  38. doi request reprint Clinical impact of a newly developed capsule endoscope: usefulness of a real-time image viewer for gastric transit abnormality
    Haruhiko Ogata
    Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan
    J Gastroenterol 43:186-92. 2008
    ..A new capsule endoscope has been developed by Olympus Medical Systems. The visualization and usefulness of its real-time image viewer for gastric transit abnormality were evaluated by using this new device...
  39. doi request reprint Human liver-specific nanocarrier in a novel mouse xenograft model bearing noncancerous human liver tissue
    Yoshifumi Matsuura
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Eur Surg Res 46:65-72. 2011
    ....
  40. doi request reprint Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cells
    Ayano Kabashima-Niibe
    Division of Gastroenterology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Cancer Sci 104:157-64. 2013
    ..Thus, our results suggest that MSC-derived myofibroblasts play important roles in regulating EMT and tumor-initiating stem cell-like properties of pancreatic cancer cells through an intermediating Notch signal...
  41. doi request reprint Clinical results of endoscopic hemostasis using a short transparent hood and short hemoclips for non-variceal upper gastrointestinal bleeding
    Naoki Hosoe
    Department of Internal Medicine, School of Medicine, Keio University, Shinjuku ku, Tokyo, Japan
    Dig Endosc 21:93-6. 2009
    ..Short clips, however, can be easily clamped on protruded visible vessels without slip. The aim of the present study was to evaluate the efficacy of endoscopic hemostasis with a short transparent hood and short clips...
  42. ncbi request reprint Evaluation of the usefulness of percutaneous transhepatic portal catheterization for preoperatively diagnosing the localization of insulinomas
    Keiichi Suzuki
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Pancreas 24:96-102. 2002
    ..The precise intraoperative localization of insulinoma is essential for successful surgical management...