K Aoki

Summary

Affiliation: Kazusa DNA Research Institute
Country: Japan

Publications

  1. ncbi An improved cosmid vector for the nested deletion method using the bacteriophage T3 DNA packaging system
    Y Kawarabayasi
    Kazusa DNA Research Institute, Chiba, Japan
    DNA Res 3:37-42. 1996
  2. ncbi Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1
    Y Kawarabayasi
    National Institute of Technology and Evaluation, Shibuya, Tokyo, Japan
    DNA Res 6:83-101, 145-52. 1999
  3. ncbi Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob
    T Nishimoto
    Section for Studies on Host Immune Response, National Cancer Center Research Institute, Chuo Ku, Tokyo, Japan
    Gene Ther 16:669-80. 2009
  4. ncbi Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7
    Y Kawarabayasi
    National Institute of Technology and Evaluation, Shibuya, Tokyo, Japan
    DNA Res 8:123-40. 2001
  5. ncbi In vivo delivery of interferon-α gene enhances tumor immunity and suppresses immunotolerance in reconstituted lymphopenic hosts
    K Narumi
    Division of Gene and Immune Medicine, National Cancer Center Research Institute, Tokyo, Japan
    Gene Ther 19:34-48. 2012
  6. ncbi Suppression of colorectal cancer growth using an adenovirus vector expressing an antisense K-ras RNA
    M Nakano
    Genetics Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan
    Mol Ther 3:491-9. 2001
  7. ncbi Participation of CYP2A in cocaine-induced hepatotoxicity in female mice
    K Aoki
    School of Pharmaceutical Sciences, Showa University, Tokyo, Japan
    Pharmacol Toxicol 87:26-32. 2000
  8. ncbi Direct selection of targeted adenovirus vectors by random peptide display on the fiber knob
    Y Miura
    Genetics Division, National Cancer Center Research Institute, Tokyo, Japan
    Gene Ther 14:1448-60. 2007
  9. ncbi Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX
    K Aoki
    Department of Immunology, National Institute of Health, Shinjuku ku, Tokyo, Japan
    FEBS Lett 401:109-12. 1997
  10. ncbi Defective nuclear factor-κB-inducing kinase in aly/aly mice prevents bone resorption induced by local injection of lipopolysaccharide
    N S Soysa
    Section of Pharmacology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Periodontal Res 46:280-4. 2011

Collaborators

Detail Information

Publications10

  1. ncbi An improved cosmid vector for the nested deletion method using the bacteriophage T3 DNA packaging system
    Y Kawarabayasi
    Kazusa DNA Research Institute, Chiba, Japan
    DNA Res 3:37-42. 1996
    ..The cosmid clone constructed by this new vector could be linearized at one of the 8-base cutter sites which are assumed to rarely occur in the genome, and followed by in vitro packaging, nested deletion clones were successfully prepared...
  2. ncbi Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1
    Y Kawarabayasi
    National Institute of Technology and Evaluation, Shibuya, Tokyo, Japan
    DNA Res 6:83-101, 145-52. 1999
    ..All the assigned ORFs and RNA coding regions occupied 89.12% of the whole genome. The data presented in this paper are available on the internet homepage (http://www.mild.nite.go.jp)...
  3. ncbi Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob
    T Nishimoto
    Section for Studies on Host Immune Response, National Cancer Center Research Institute, Chuo Ku, Tokyo, Japan
    Gene Ther 16:669-80. 2009
    ..The results showed that a tumor-targeting strategy using an adenovirus library is promising for optimizing the safety and efficacy of oncolytic adenovirus therapy...
  4. ncbi Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7
    Y Kawarabayasi
    National Institute of Technology and Evaluation, Shibuya, Tokyo, Japan
    DNA Res 8:123-40. 2001
    ..The result suggests that this strain is closer to eukaryotes among the archaea strains so far sequenced. The data presented in this paper are also available on the internet homepage (http://www.bio.nite.go.jp/E-home/genome_list-e.html/)...
  5. ncbi In vivo delivery of interferon-α gene enhances tumor immunity and suppresses immunotolerance in reconstituted lymphopenic hosts
    K Narumi
    Division of Gene and Immune Medicine, National Cancer Center Research Institute, Tokyo, Japan
    Gene Ther 19:34-48. 2012
    ....
  6. ncbi Suppression of colorectal cancer growth using an adenovirus vector expressing an antisense K-ras RNA
    M Nakano
    Genetics Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan
    Mol Ther 3:491-9. 2001
    ..This study shows that the adenovirus-mediated in vivo gene transfer of the antisense K-ras construct may be a useful therapeutic strategy for colorectal cancer...
  7. ncbi Participation of CYP2A in cocaine-induced hepatotoxicity in female mice
    K Aoki
    School of Pharmaceutical Sciences, Showa University, Tokyo, Japan
    Pharmacol Toxicol 87:26-32. 2000
    ..These results suggest that cocaine-induced hepatotoxicity in female mice was mediated in part by CYP2A, participating in cocaine N-demethylation...
  8. ncbi Direct selection of targeted adenovirus vectors by random peptide display on the fiber knob
    Y Miura
    Genetics Division, National Cancer Center Research Institute, Tokyo, Japan
    Gene Ther 14:1448-60. 2007
    ..This vector-screening system can facilitate the development of a targeted adenovirus vector for a variety of applications in medicine...
  9. ncbi Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX
    K Aoki
    Department of Immunology, National Institute of Health, Shinjuku ku, Tokyo, Japan
    FEBS Lett 401:109-12. 1997
    ..The TRAX protein was established to contain bipartite nuclear targeting sequences in its N-terminal region, suggesting a possible role in the selective nuclear transport of Translin protein lacking any nuclear targeting motifs...
  10. ncbi Defective nuclear factor-κB-inducing kinase in aly/aly mice prevents bone resorption induced by local injection of lipopolysaccharide
    N S Soysa
    Section of Pharmacology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Periodontal Res 46:280-4. 2011
    ..Nevertheless, the role of NIK in pathological bone resorption is not well investigated. The present study was undertaken to investigate the role of NIK in lipopolysaccharide (LPS)-induced inflammatory bone resorption using aly/aly mice...