Yoshihiro Kobashi

Summary

Affiliation: Kawasaki Medical School
Country: Japan

Publications

  1. ncbi request reprint Mucoid impaction of the bronchi caused by Mycobacterium avium
    Yoshihiro Kobashi
    Department of Respiratory Medicine, Kawasaki Medical School, Japan
    Intern Med 52:1537-40. 2013
  2. doi request reprint Serological assay by use of glycopeptidolipid core antigen for Mycobacterium avium complex
    Yoshihiro Kobashi
    Department of Respiratory Medicine, Kawasaki Medical School, Kurashiki, Japan
    Scand J Infect Dis 45:241-9. 2013
  3. ncbi request reprint Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan
    Intern Med 51:1923-6. 2012
  4. doi request reprint Relationship between clinical efficacy for pulmonary MAC and drug-sensitivity test for isolated MAC in a recent 6-year period
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Japan
    J Infect Chemother 18:436-43. 2012
  5. ncbi request reprint Usefulness of tuberculin skin test and three interferon-gamma release assays for the differential diagnosis of pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan
    Intern Med 51:1199-205. 2012
  6. pmc Radiographic features of Mycoplasma pneumoniae pneumonia: differential diagnosis and performance timing
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    BMC Med Imaging 9:7. 2009
  7. ncbi request reprint Clinical evaluation of QuantiFERON TB-2G test for immunocompromised patients
    Y Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Eur Respir J 30:945-50. 2007
  8. ncbi request reprint Usefulness of QuantiFERON TB-2G, a diagnostic method for latent tuberculosis infection, in a contact investigation of health care workers
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki
    Intern Med 46:1543-9. 2007
  9. ncbi request reprint Clinical features of immunocompromised and nonimmunocompromised patients with pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 13:405-10. 2007
  10. ncbi request reprint An indeterminate QuantiFERON TB-2G response for miliary tuberculosis, due to severe pancytopenia
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    J Infect Chemother 13:414-7. 2007

Detail Information

Publications94

  1. ncbi request reprint Mucoid impaction of the bronchi caused by Mycobacterium avium
    Yoshihiro Kobashi
    Department of Respiratory Medicine, Kawasaki Medical School, Japan
    Intern Med 52:1537-40. 2013
    ..As the histological findings revealed a granuloma with caseating necrosis and mucous plugs containing M. avium in the respiratory bronchioles, we diagnosed the patient with mucoid impaction of the bronchi (MIB) due to M. avium. ..
  2. doi request reprint Serological assay by use of glycopeptidolipid core antigen for Mycobacterium avium complex
    Yoshihiro Kobashi
    Department of Respiratory Medicine, Kawasaki Medical School, Kurashiki, Japan
    Scand J Infect Dis 45:241-9. 2013
    ..We evaluated the clinical usefulness of glycopeptidolipid (GPL) core antigen for diagnosing Mycobacterium avium complex (MAC) pulmonary disease (MAC-PD), including patients with clinically suspected MAC-PD...
  3. ncbi request reprint Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan
    Intern Med 51:1923-6. 2012
    ..Clarithromycin and levofloxacin were administered after identification of M. kyorinense using a 16S rRNA gene sequence. Subsequently his symptoms improved following combined therapy with clarithromycin and levofloxacin...
  4. doi request reprint Relationship between clinical efficacy for pulmonary MAC and drug-sensitivity test for isolated MAC in a recent 6-year period
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Japan
    J Infect Chemother 18:436-43. 2012
    ..Good clinical efficacy, including the sputum conversion rate, was obtained with an increased dose of CAM in the later period. We speculate that the increased dose of CAM influenced the good clinical effect in both periods...
  5. ncbi request reprint Usefulness of tuberculin skin test and three interferon-gamma release assays for the differential diagnosis of pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan
    Intern Med 51:1199-205. 2012
    ..TB] as the supportive method for diagnosing pulmonary tuberculosis (TB)...
  6. pmc Radiographic features of Mycoplasma pneumoniae pneumonia: differential diagnosis and performance timing
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    BMC Med Imaging 9:7. 2009
    ..pneumoniae pneumonia from Streptococcus pneumoniae pneumonia...
  7. ncbi request reprint Clinical evaluation of QuantiFERON TB-2G test for immunocompromised patients
    Y Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Eur Respir J 30:945-50. 2007
    ....
  8. ncbi request reprint Usefulness of QuantiFERON TB-2G, a diagnostic method for latent tuberculosis infection, in a contact investigation of health care workers
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki
    Intern Med 46:1543-9. 2007
    ..To evaluate the usefulness of QuantiFERON TB-2G (QFT-2G) for detecting latent tuberculosis infection (LTBI) in a contact investigation of health care workers...
  9. ncbi request reprint Clinical features of immunocompromised and nonimmunocompromised patients with pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 13:405-10. 2007
    ..We must perform the acid-fast bacilli examination for patients who have a fever and continuous cough, and antituberculous drugs should be administered as soon as possible when the results are positive...
  10. ncbi request reprint An indeterminate QuantiFERON TB-2G response for miliary tuberculosis, due to severe pancytopenia
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    J Infect Chemother 13:414-7. 2007
    ..This patient was treated with antituberculous drugs 3 days after admission, but he died of multiple organ failure 6 days after admission...
  11. ncbi request reprint Usefulness of the QuantiFERON TB-2G test for the differential diagnosis of pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 47:237-43. 2008
    ..We prospectively evaluated the usefulness of the QuantiFERON TB-2G (QFT-2G) compared to that of tuberculin skin test (TST) as a supportive method of diagnosing pulmonary tuberculosis (TB) without invasive examinations...
  12. doi request reprint Multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis: differentiation from multiple atypical adenomatous hyperplasia
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    Jpn J Clin Oncol 38:451-4. 2008
    ..We must consider MMPH as part of the differential diagnosis along with multiple AAH when multiple small nodules with ground-glass opacity were observed on chest CT in patients with TSC...
  13. doi request reprint Indeterminate results of QuantiFERON TB-2G test performed in routine clinical practice
    Y Kobashi
    Division of Respiratory Diseases, Dept of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Eur Respir J 33:812-5. 2009
    ..When scoring QuantiFERON TB-2G test results for elderly and immunocompromised patients, one must be careful because the possibility of obtaining determinate results may be low even if the test is repeated...
  14. ncbi request reprint Transitional change in the clinical features of pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respiration 75:304-9. 2008
    ..An aging population, increased use of immunosuppressive therapy and an increase in patients with risk factors for tuberculosis have induced changes in the clinical features of pulmonary tuberculosis in Japan...
  15. ncbi request reprint Inflammatory pseudotumor of the lung: clinicopathological analysis in seven adult patients
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    Int J Clin Oncol 11:461-6. 2006
    ..As the origin and pathology of inflammatory pseudotumor is not clearly understood, there has recently been some confusion regarding the diagnosis of inflammatory pseudotumor...
  16. ncbi request reprint Clinical reevaluation of the QuantiFERON TB-2G test as a diagnostic method for differentiating active tuberculosis from nontuberculous mycobacteriosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, 701 0192, Japan
    Clin Infect Dis 43:1540-6. 2006
    ....
  17. ncbi request reprint Sibling cases of Mycobacterium avium complex disease associated with hematological disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Japan
    J Infect Chemother 12:331-4. 2006
    ..We suspect that they were infected by different species of Mycobacterium avium in the same environment rather than by droplet infection from the younger brother to the older brother...
  18. ncbi request reprint Chronic necrotizing pulmonary aspergillosis as a complication of pulmonary Mycobacterium avium complex disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respirology 11:809-13. 2006
    ..To investigate the characteristic clinical features of chronic necrotizing pulmonary aspergillosis (CNPA) as a complication of pulmonary Mycobacterium avium complex (MAC) disease...
  19. ncbi request reprint Pulmonary Mycobacterium intracellulare disease with a solitary pulmonary nodule detected at the onset of pneumothorax
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 12:203-6. 2006
    ..We have reported a peculiar case of pulmonary M. intracellulare disease, detected at the onset of left secondary pneumothorax caused by pulmonary emphysema, which required differentiation from pulmonary adenocarcinoma...
  20. ncbi request reprint Relationship between clinical efficacy of treatment of pulmonary Mycobacterium avium complex disease and drug-sensitivity testing of Mycobacterium avium complex isolates
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 12:195-202. 2006
    ..Although the ATS has not yet recommended routine drug susceptibility testing of CAM, we believe that drug susceptibility testing of CAM should be performed before the initial treatment is undertaken for pulmonary MAC disease...
  21. ncbi request reprint A double-blind randomized study of aminoglycoside infusion with combined therapy for pulmonary Mycobacterium avium complex disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Respir Med 101:130-8. 2007
    ....
  22. doi request reprint Clinical evaluation for diagnosing active TB disease and transitional change of two commercial blood tests
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Scand J Infect Dis 40:629-34. 2008
    ..In conclusion, both blood assays seemed to be more useful than TST for the identification of patients with active TB disease. However, neither of the 2 blood tests appears to provide any certainty regarding the cure of infection...
  23. doi request reprint Clinicopathological analysis of multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis in Japan
    Yoshihiro Kobashi
    Department of Medicine, Division of Respiratory Diseases, Kawasaki Medical School, Kurashiki, Japan
    Respirology 13:1076-81. 2008
    ..This study investigated the clinical and pathological findings of lung disease in tuberous sclerosis complex (TSC) as previously reported in Japan...
  24. doi request reprint Transitional changes in T-cell responses to Mycobacterium tuberculosis-specific antigens during treatment
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    J Infect 58:197-204. 2009
    ..Therefore, we studied the usefulness of two commercial IFN-gamma assays (QuantiFERON TB-2G (QFT-2G) and T-SPOT.TB tests) for monitoring clinical efficacy...
  25. ncbi request reprint Pulmonary Mycobacterium massiliense disease with septicemia during immunosuppressive treatment
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan
    Intern Med 50:1069-73. 2011
    ..However, he died of respiratory failure and septic shock. There are few case reports of pulmonary lesion with septicemia due to Mycobacterium massiliense...
  26. pmc Comparison of T-cell interferon-gamma release assays for Mycobacterium tuberculosis-specific antigens in patients with active and latent tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Japan
    Lung 188:283-7. 2010
    ..However, there was an overlap in the IFN-gamma levels between active TB disease and LTBI groups. Therefore, it would be difficult to use the QFT-2G test to completely discriminate active TB disease from LTBI...
  27. doi request reprint Rapid diagnosis of tuberculous pericarditis by ELISPOT assay
    Yoshihiro Kobashi
    Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Scand J Infect Dis 42:712-5. 2010
    ..The analysis of MTB-specific T-cells in PEMCs by ELISPOT may be useful for rapid decision-making in anti-tuberculous treatment...
  28. doi request reprint QuantiFERON TB-2G test for patients with active tuberculosis stratified by age groups
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Scand J Infect Dis 41:841-6. 2009
    ..Although the positive rate on QFT-2G test decreased with age in adults, it is thought to be a useful supportive diagnostic method for active TB disease compared to the TST, except in younger patients aged < or =9 years old...
  29. ncbi request reprint Clinical usefulness of fluoro-2-deoxy-D-glucose PET in a case with multiple bone metastases of carcinoid tumor after ten years
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 48:1919-23. 2009
    ....
  30. ncbi request reprint Clinical evaluation of the QuantiFERON-TB Gold test in patients with non-tuberculous mycobacterial disease
    Y Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Int J Tuberc Lung Dis 13:1422-6. 2009
    ..To evaluate the clinical usefulness of the QuantiFERON TB-2G (QFT-2G) test in patients with non-tuberculous mycobacterial (NTM) disease without a previous history of tuberculosis (TB)...
  31. ncbi request reprint False negative results of QuantiFERON TB-2G test in patients with active tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Jpn J Infect Dis 62:300-2. 2009
    ....
  32. ncbi request reprint Clinical usefulness of QuantiFERON TB-2G test for the early diagnosis of pulmonary Mycobacterium kansasii disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki 701 0192, Japan
    Jpn J Infect Dis 62:239-41. 2009
    ..The QFT-2G test may be useful as a rapid supportive diagnostic method for pulmonary infection due to MK possessing the same MTB-specific antigen...
  33. doi request reprint Clinical utility of a T cell-based assay in the diagnosis of extrapulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Respirology 14:276-81. 2009
    ....
  34. ncbi request reprint Clinical evaluation of the T-SPOT.TB test for patients with indeterminate results on the QuantiFERON TB-2G test
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Intern Med 48:137-42. 2009
    ..To evaluate the clinical utility of the T-SPOT.TB test for patients with indeterminate results on the QFT-2G test...
  35. ncbi request reprint [Long-term observation of pulmonary Mycobacterium avium complex disease treated with chemotherapy-- following the guidelines for treatment]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki shi, Okayama 701 0192, Japan
    Kekkaku 83:779-84. 2008
    ..We also studied when to terminate the combined chemotherapy...
  36. doi request reprint Rapid diagnosis of tuberculous pleuritis by a T-cell interferon-gamma release assay
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Scand J Infect Dis 41:232-6. 2009
    ..to analyze MTB-specific T-cells in pleural effusion mononuclear cells by ELISpot is feasible in routine clinical practice and may be useful for a rapid and accurate diagnosis of tuberculous pleuritis...
  37. ncbi request reprint Clinical analysis of cases of empyema due to Streptococcus milleri group
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Jpn J Infect Dis 61:484-6. 2008
    ..The duration of hospitalization was 19.6 days. The clinical effect of treatment was comparatively good (93%), and the prognosis was also good (mortality rate 7%)...
  38. ncbi request reprint Long-term follow-up of the QuantiFERON TB-2G test for active tuberculosis disease
    Yoshihiro Kobashi
    Department of Medicine, Division of Respiratory Diseases, Kawasaki Medical School, Kurashiki
    Intern Med 47:1957-61. 2008
    ..To evaluate transitional changes in QuantiFERON TB-2G (QFT-2G) test results in the serial testing on the same patients and to reevaluate the optimal threshold of positive response of QFT-2G test as a cure of TB infection...
  39. ncbi request reprint Four cases of pulmonary Mycobacterium avium intracellulare complex presenting as a solitary pulmonary nodule and a review of other cases in Japan
    Yoshihiro Kobashi
    Department of Medicine, Division of Respiratory Diseases, Kawasaki Medical School, Kawasaki, Japan
    Respirology 11:317-21. 2006
    ..To evaluate clinical findings of patients with a solitary pulmonary nodule in Japan caused by pulmonary Mycobacterium avium complex (MAC) disease...
  40. ncbi request reprint [Clinical analysis of Mycobacterium abscessus pulmonary infection in our hospital]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama, Japan
    Kekkaku 85:1-6. 2010
    ..We analyzed the clinical characteristics of pulmonary infection due to Mycobacterium abscessus...
  41. ncbi request reprint Evaluating the use of a Streptococcus pneumoniae urinary antigen detection kit for the management of community-acquired pneumonia in Japan
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respiration 74:387-93. 2007
    ..The urinary antigen detection kit for Streptococcus pneumoniae was tested...
  42. doi request reprint Clinical utility of the QuantiFERON TB-2G test for elderly patients with active tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Japan
    Chest 133:1196-202. 2008
    ....
  43. ncbi request reprint Chronic necrotizing pulmonary aspergillosis complicated by a cavitary lesion caused by Pulmonary Mycobacterium-avium complex disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192
    Intern Med 44:246-50. 2005
    ....
  44. ncbi request reprint [A case of pulmonary Mycobacterium intracellulare infectious disease with a solitary pulmonary nodule in the peripheral lung field]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Nihon Kokyuki Gakkai Zasshi 42:831-6. 2004
    ..We report a rare case with a solitary nodule caused by pulmonary Mycobacterium intracellulare infectious disease which is indicative of lung cancer...
  45. doi request reprint Step-down of budesonide/formoterol in early stages of asthma treatment leads to insufficient anti-inflammatory effect
    Yasushi Obase
    Department of Respiratory Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    J Asthma 50:718-21. 2013
    ..In this study, we obtained fractional exhaled nitric oxide (FeNO) measurements to clarify whether the anti-inflammatory effect of budesonide/formoterol is shortened by step-down...
  46. ncbi request reprint Pulmonary Mycobacterium avium disease with a solitary pulmonary nodule requiring differentiation from recurrence of pulmonary adenocarcinoma
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki
    Intern Med 43:855-60. 2004
    ..As the causative pathogen, Mycobacterium avium complex (MAC) disease should be considered in the differential diagnosis of a rapidly increasing solitary nodule through this peculiar case of pulmonary MAC disease...
  47. ncbi request reprint Comparison of clinical features in patients with pulmonary Mycobacterium-avium complex (MAC) disease treated before and after proposal for guidelines
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    J Infect Chemother 10:25-30. 2004
    ..Therefore, we anticipate the development of new companion drugs for pulmonary MAC disease that are as active as CAM...
  48. doi request reprint Stability of sealed-bag samples for off-line measurement of fractional exhaled nitric oxide
    Hiroki Shimizu
    Department of Respiratory Medicine, Kawasaki Medical School, Japan
    Ann Allergy Asthma Immunol 106:378-80. 2011
    ..It can be measured with on- and off-line methods. In the latter, sample storage is possible; this is useful in Japan, because the number of facilities in which this instrument has been installed is limited...
  49. ncbi request reprint [Clinical analysis of pulmonary actinomycosis]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 79:111-6. 2005
    ..Because penicillin antibiotics were administered for a long time for all patients after obtaining a definite diagnosis, the prognosis was good and there were no relapse...
  50. doi request reprint Clinical evaluation of QuantiFERON TB-2G test in patients with healed pulmonary tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 15:288-92. 2009
    ....
  51. ncbi request reprint Assessment of the usefulness of sputum Gram stain and culture for diagnosis of community-acquired pneumonia requiring hospitalization
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Med Sci Monit 14:CR171-6. 2008
    ..The usefulness of sputum Gram stain and culture in guiding microbiological diagnosis of community-acquired pneumonia (CAP) is controversial. We evaluated the role of sputum examination at a university teaching hospital...
  52. doi request reprint An asymptomatic case of pulmonary cryptococcosis with endobronchial polypoid lesions and bilateral infiltrative shadow
    Hiroki Shimizu
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    J Infect Chemother 14:315-8. 2008
    ..Histopathological examination of transbronchial biopsy specimens demonstrated cryptococcal organisms. After fluconazole therapy for 4 months, the infiltrate had decreased in size and the bronchial polypoid lesions had disappeared...
  53. ncbi request reprint The microbiological and clinical effects of combined therapy according to guidelines on the treatment of pulmonary Mycobacterium avium complex disease in Japan - including a follow-up study
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respiration 74:394-400. 2007
    ..The difficulty of treatment for pulmonary Mycobacterium avium complex (MAC) in Japan...
  54. ncbi request reprint [Current status of patients discharging Mycobacterium tuberculosis after admission to Kawasaki Medical School Hospital]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki shi, Okayama 701 0192, Japan
    Kekkaku 80:57-62. 2005
    ..To investigate the current status of patients with tuberculosis in Kawasaki Medical School Hospital which has closed tuberculosis isolation ward and review the nosocomial tuberculosis infection control...
  55. ncbi request reprint Community-acquired pneumonia in Japan: a prospective ambulatory and hospitalized patient study
    Naoyuki Miyashita
    Division of Respiratory Disease, Department of Internal Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701 0192, Japan
    J Med Microbiol 54:395-400. 2005
    ..pneumoniae and Haemophilus influenzae was higher among the hospitalized patients. Recognition of these results will allow prompt and appropriate antimicrobial therapy to be provided using Japanese CAP guidelines...
  56. ncbi request reprint [Clinical usefulness of the (1-->3)-beta-D-glucan measurement kit using the improved alkaline pretreatment method--comparison with conventional method]
    Koichiro Yoshida
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 80:701-5. 2006
    ..Then, the specificity of new MK assay was improved by using improved alkaline pretreatment reagent, without decreasing the sensitivity. Thus, the present findings indicate that the new MK assay is clinically quite useful...
  57. ncbi request reprint The effect of combined therapy according to the guidelines for the treatment of Mycobacterium avium complex pulmonary disease
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki
    Intern Med 42:670-5. 2003
    ....
  58. ncbi request reprint Mycoplasma pneumoniae pneumonia in the elderly
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Med Sci Monit 14:CR387-91. 2008
    ..Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia (CAP). This infection occurs predominantly in school-aged children and younger adults, but may also occur in the elderly...
  59. ncbi request reprint Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki
    Intern Med 44:616-21. 2005
    ..Concerning treatment, although corticosteroid therapy was administered, his clinical symptoms and abnormal chest shadow have not changed...
  60. ncbi request reprint [A case of pulmonary adenocarcinoma coexistent with Igusa pneumoconiosis in one segment of the lung]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki
    Nihon Kokyuki Gakkai Zasshi 42:537-41. 2004
    ....
  61. ncbi request reprint Self-limiting pneumonia due to Chlamydia pneumoniae
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Intern Med 44:870-4. 2005
    ..pneumoniae pneumonia is rarely encountered, although self-limiting upper respiratory tract infections due to C. pneumoniae are common. Thus, most self-limiting C. pneumoniae pneumonia may be missed when symptoms are minimal...
  62. ncbi request reprint Solitary pulmonary nodule due to Mycobacterium kansasii
    Masaaki Abe
    Department of Medicine, Kawasaki Medical School, Japan
    Intern Med 50:775-8. 2011
    ..Smear test of the resected tissue was positive for acid-fast bacilli and culture was positive for mycobacteria, which was identified as Mycobacterium kansasii. There are a few case reports of solitary nodule due to M. kansasii...
  63. ncbi request reprint [Non-specific reactions in four methods measuring (1-->3)-beta-D-glucan levels in plasma]
    Koichiro Yoshida
    Division of Repiratory Disease, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 79:329-40. 2005
    ..Finally, to measure plasma beta-glucan levels accurately, non-specific reactions should be excluded as possible by further improvement of measurement methods...
  64. doi request reprint Evaluation of enzyme-linked immunosorbent assay for Chlamydophila pneumoniae-specific immunoglobulin M in acute respiratory tract infection
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan
    Respirology 13:299-302. 2008
    ..The study evaluated a newly developed ELISA (Hitazyme Chlamydophila pneumoniae) for detecting anti-C. pneumoniae-specific IgM antibody, by comparing the ELISA assay to a microimmunofluorescence (MIF) test and immunoblotting...
  65. ncbi request reprint Multifocal micronodular pneumocyte hyperplasia in a man with tuberous sclerosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, The Department of Medicine, Kurashiki Medical School, Japan
    Intern Med 44:462-6. 2005
    ....
  66. ncbi request reprint Paclitaxel and cisplatin with concurrent radiotherapy followed by surgery in locally advanced thymic carcinoma
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama, Japan
    Anticancer Res 27:1601-4. 2007
    ..She is currently alive and ambulatory and has remained disease-free for two years. This multimodal treatment may be a good treatment option for locally advanced thymic carcinoma...
  67. ncbi request reprint [Comparison of clinical presentation of mixed pneumonia with Chlamydia pneumoniae and Streptococcus pneumoniae and S. pneumoniae pneumonia]
    Hiroshi Fukano
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 78:108-13. 2004
    ..Our results indicated that C. pneumoniae may not be the primary cause of community-acquired pneumonia but it might descript the normal clearance mechanisms, enabling other pathogens to invade...
  68. ncbi request reprint [A case of pulmonary adenosquamous cell carcinoma with thin-wall cavities]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Nihon Kokyuki Gakkai Zasshi 43:59-62. 2005
    ..Herein, we have reported a rare case of histological diagnosis of pulmonary adenosquamous cell carcinoma with cavity formation...
  69. ncbi request reprint [Epidemic status of influenza virus between 2004-2005 and 2005-2006 at Kawasaki Medical School Hospital]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 81:435-40. 2007
    ..In spite of influenza vaccination inoculation in 20% of patients with influenza in 2004-2005 and 2005-2006, influenza spread. The prognosis of these patients, however, was comparatively good...
  70. ncbi request reprint Clinicopathological analysis of lung cancer resembling malignant pleural mesothelioma
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan
    Respirology 10:660-5. 2005
    ..The aim of this study was to evaluate the clinicopathological features of lung cancer resembling malignant pleural mesothelioma...
  71. ncbi request reprint Synchronus presentation of early-stage small cell carcinoma and adenocarcinoma in the same lung lobe
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima, Kurashiki
    Intern Med 45:287-91. 2006
    ....
  72. ncbi request reprint Squamous cell carcinoma of the lung producing granulocyte colony-stimulating factor and resembling a malignant pleural mesothelioma
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192
    Intern Med 43:111-6. 2004
    ..Based on positive staining method with specific monoclonal antibodies against G-CSF, it was considered that the leukocytosis was caused by G-CSF producing tumor...
  73. ncbi request reprint [Effect of combined chemotherapy following the guidelines on treatment for Mycobacterium avium complex pulmonary disease]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kawasaki Hospital, 2 1 80, Nakasange, Okayamashi, Okayama 700 8505, Japan
    Kekkaku 77:435-41. 2002
    ..Therefore, the development of new companion drugs for the disease with mycobacteria other than M. tuberculosis is needed...
  74. ncbi request reprint [A case of mixed pulmonary infection with Mycobacterium tuberculosis and M. intracellulare due to familial prevalence]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kawasaki Hospital, Nakasange 2 1 80, Okayama, Japan
    Nihon Kokyuki Gakkai Zasshi 40:35-9. 2002
    ..The RFLP analysis revealed the same pattern in both mother and son, and confirmed that this was a case of mixed pulmonary infection passed from son to mother...
  75. ncbi request reprint [Clinical analysis of pulmonary tuberculosis found by mass screening medical examination]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki shi, Okayama 701 0192, Japan
    Kekkaku 78:383-7. 2003
    ..However, early diagnosis using bronchoscopy and early treatment seems to be useful, when Mycobacterium tuberculosis is not detected in the sputum...
  76. ncbi request reprint [Clinical evaluation of the cause of death in patients with active pulmonary tuberculosis]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kawasaki Medical School Kawasaki Hospital
    Kekkaku 77:771-5. 2002
    ..Therefore, treatment should be considered against resistant microoganisms such as MRSA...
  77. ncbi request reprint Clinical features of severe Mycoplasma pneumoniae pneumonia in adults admitted to an intensive care unit
    Naoyuki Miyashita
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama 701 0192, Japan
    J Med Microbiol 56:1625-9. 2007
    ..The delayed administration of adequate antibiotics may contribute to the severity of M. pneumoniae pneumonia. Early corticosteroid therapy with adequate antibiotics should be considered...
  78. ncbi request reprint Coexistence of metastatic lung cancer and pulmonary tuberculosis diagnosed in the same cavity
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701 0192, Japan
    Int J Clin Oncol 10:366-70. 2005
    ..We report a rare case of the coexistence of metastatic lung cancer originating from tongue cancer and active pulmonary tuberculosis diagnosed in the same large cavitary lesion...
  79. ncbi request reprint Clinical analysis of pulmonary tuberculosis in association with corticosteroid therapy
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital, Okayama
    Intern Med 41:1103-10. 2002
    ..Due to the increased incidence of pulmonary tuberculosis in association with corticosteroid therapy during the last five years in our associated hospitals, we studied the clinical characteristics of these patients...
  80. ncbi request reprint Clinical analysis of pulmonary Mycobacterium avium complex disease in association with corticosteroid treatment
    Yoshihiro Kobashi
    The Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 9:68-74. 2003
    ....
  81. ncbi request reprint [Clinical analysis of pulmonary tuberculosis detected during follow-up of other underlying diseases]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki shi, Okayama 701 0192, Japan
    Kekkaku 79:1-6. 2004
    ....
  82. ncbi request reprint Thoracic actinomycosis with mainly pleural involvement
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, 701 0192, Kurashiki, Japan
    J Infect Chemother 10:172-7. 2004
    ....
  83. ncbi request reprint [A case of pulmonary Mycobacterium avium complex disease complicated by interstitial pneumonia with collagen vascular disease]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki shi, Okayama 701 0192, Japan
    Kekkaku 78:487-90. 2003
    ....
  84. ncbi request reprint Clinical analysis of recent lower lung field tuberculosis
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577, Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 9:272-5. 2003
    ..We consider this problem to be not so difficult considering the progress in diagnostic methods for M. tuberculosis...
  85. ncbi request reprint Infectious bulla of the lung caused by Mycobacterium intracellulare
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki 701 0192, Japan
    J Infect Chemother 11:293-6. 2005
    ..We report this case because there have been no previous reports in the literature of infectious lung bulla caused by M. intracellulare although there have been several reports dealing with lung bulla caused by Mycobacterium tuberculosis...
  86. ncbi request reprint Clinical analysis of patients requiring long-term mechanical ventilation of over three months: ventilator-associated pneumonia as a primary complication
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital, 2 1 80 Nakasange, Okayama 700 8505
    Intern Med 42:25-32. 2003
    ....
  87. ncbi request reprint [Pneumonia associated with lung cancer in the elderly]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kawasaki Hospital, Nakasange 2 1 80, Okayama 700 8505, Japan
    Kansenshogaku Zasshi 76:188-94. 2002
    ....
  88. ncbi request reprint [A case of pulmonary infection induced by both Aspergillus sp. and Mycobacterium tuberculosis during corticosteroid therapy]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kawasaki Hospital, Nakasange 2 1 80, Okayama 700 8505, Japan
    Nihon Kokyuki Gakkai Zasshi 40:230-5. 2002
    ..We considered this a case of interest because 20 months after the diagnosis of pulmonary aspergillosis, a mixed pulmonary infection of Mycobacterium tuberculosis and Aspergillus sp. was identified...
  89. ncbi request reprint Both bronchial and vascular stenting followed by chemoradiotherapy for locally advanced non-small cell lung cancer
    Minoru Fukuda
    Division of Respiratory Diseases, Department of Medicine and Kawasaki Medical School, Okayama, Japan
    Anticancer Res 26:565-7. 2006
    ..Both endobronchial and endovascular stenting prior to antitumor therapy may be beneficial in the treatment of locally advanced cases of lung cancer...
  90. ncbi request reprint Comparative study of mediastinal emphysema as determined by etiology
    Yoshihiro Kobashi
    Department of Medicine, Kawasaki Medical School Kawasaki Hospital, Okayama
    Intern Med 41:277-82. 2002
    ....
  91. ncbi request reprint [Evaluation of a new standard beta-glucan CSBG in the measurement of beta-glucan in plasma by alkaline treatment, chromogenic automated kinetic assay]
    Koichiro Yoshida
    Kansenshogaku Zasshi 78:519-21. 2004
  92. ncbi request reprint [Quinolone]
    Yoshihito Niki
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Nihon Rinsho 61:750-5. 2003
  93. ncbi request reprint [A case of silicoproteinosis with pneumothorax]
    Yoshihiro Kobashi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Matsushima 577, Kurashiki 701 0192, Japan
    Nihon Kokyuki Gakkai Zasshi 41:117-22. 2003
    ..We have reported on this case of silicoproteinosis with pneumothorax which progressed for over one year and which showed unusual radiological findings dissimilar to those of primary pulmonary alveolar proteinosis...
  94. ncbi request reprint [Countermeasures against non-specific reactions in the measurement of beta-glucan in plasma by alkaline treatment, chromogenic automated kinetic assay]
    Koichiro Yoshida
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School
    Kansenshogaku Zasshi 78:435-41. 2004
    ..By so doing, unnecessary initiation of anti fugal therapy in response to non-specific reactions can be avoided. Further prospective and radical studies of non-specific reactions in the alkaline-kinetic assay are necessary...