Y Iguchi

..A community-based study was conducted to estimate the prevalence of atrial fibrillation (AF) in Japanese adults aged >or=40 years in Kurashiki-city and to examine associated risk factors...

..To investigate stroke incidence and rate of thrombolytic therapy in an urban city of around 500,000 residents...

..The aim of the present study was to investigate whether the prevalence of atrial fibrillation (AF) is associated with the level of glycated hemoglobin (HbA1c) in Japanese adults in Kurashiki-city...

..We investigated whether new ischaemic lesions (NIL) on follow-up diffusion weighted magnetic resonance imaging (DWI) are associated with microembolic signals (MES) within 24 h or at 48 h after stroke onset...

..After MRA showed the development of stenotic lesions 10 days after first TCD monitoring, MES were absent. MES may be related to the clinical activity of Moyamoya disease...

..Cryptogenic stroke is caused by a right-to-left shunt (RLS). The present study investigated whether RLS is associated with the occurrence of sudden deafness...

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..If MES is detectable at 7 days after stroke onset, embolic source lesions may still be active. We hypothesized that presence of MES at 7 days after stroke onset is strongly associated with stroke recurrence...

..We studied the frequency and clinical characteristics of stroke patients presenting with aortic dissection within 3 hours of onset...

..Our aim was to investigate the relationship between the number of stroke physicians (SPs) and management of intravenous thrombolysis using recombinant tissue plasminogen activator (IV rt-PA) in Japan...

..The aim of this study was to investigate whether physiological factors, including body mass index (BMI), are associated with detection of right-to-left shunt (RLS) by contrast transcranial Doppler ultrasonography (c-TCD)...

..47, 95% CI 5.79 to 9.63, p < 0.001), increasing estimated glomerular filtration rate of 10 ml/min/1.73 m(2) (OR 0.93, 95% CI 0.87 to 0.99, p = 0.025), and hypercholesterolemia (OR 0.75, 95% CI 0.58 to 0.96, p = 0.023)...

..Although ischaemic stroke with malignancy occasionally occurs, the mechanisms of stroke in such cases have not been investigated in detail...

..After the presence of microembolic signals on TCD display, dynamic flow changes of the middle cerebral artery (MCA) occurred, which represented recanalization of the occluded MCA...

..Our aim was to confirm the utility of paramedics using the Kurashiki Prehospital Stroke Scale (KPSS), with a maximum score of 13, for patients who may be eligible for administration of intravenous tissue plasminogen activator (IV t-PA)...

..12 (95% confidence interval 0.88 to 1.42, p = 0.364) for the middle-GFR tertile versus the high tertile. The prevalence of AF gradually increased with decreasing GFR. In conclusion, AF appears to be associated with decreasing GFR...

..Apparent diffusion coefficient values in these lesions increased, but normalized over 2 months. These findings indicate that cortical lesions in patients with neuropsychiatric lupus could represent vasogenic oedema...

..The present study aimed to identify differences in stroke etiology between in-hospital and out-of-hospital onset...

..Our aim was to investigate the relationship between number of stroke physicians (SPs) and number of patients treated with intravenous thrombolysis (IV rt-PA) per year...

..Neurosonology appears to be useful for diagnosing and evaluating BHS...

..The aim of this study was to examine the frequency and clarify the clinical characteristics of paradoxical brain embolism (PBE)...

..We investigated whether the plasma brain natriuretic peptide (BNP) level on admission can serve as a biological marker of in-hospital death in acute ischaemic stroke and transient ischaemic attack (TIA) patients with AF...

..Multiple imaging modalities were used, allowing rapid diagnosis of paradoxical embolism, with an underlying DVT as the mechanism of stroke. Of all the investigations, visualization with TEE proved crucial in confirming the diagnosis...

..RLS was also independently associated with the non-HDM group. Thus, RLS may contribute to lacunar stroke in patients without risk factors for lacunar stroke...

..The aim of this study is to assess contrast-enhanced transcranial color-coded duplex sonography (CE-TCCS) diagnosis of basilar artery (BA) stenosis...

..Right-to-left shunt (RLS) is one of the most important etiologies of cryptogenic stroke. The aim of this study was to determine whether RLS is related to transient ischemic attack (TIA) of unknown etiology...

..We investigated whether the plasma BNP level can also be used as a biological marker to differentiate specific stroke subtype, in particular cardioembolic stroke from the other ischemic stroke subtypes...

..We investigated clinical characteristics and patient outcome in patients with and without AF after t-PA therapy...

..The ACL scale can predict the presence of aortic complicated lesions...

..Serial gradient recalled-echo T2*-weighted imaging (T2*WI) studies demonstrated dynamic changes of thrombosed segments. T2*WI is useful not only as a diagnostic tool for CVT, but also in evaluating changes to thrombus...

..Brain natriuretic peptide (BNP) is used as a biological marker of heart failure. We hypothesized that heart failure was associated with the onset of ischemic stroke patients with atrial fibrillation (AF)...

..She was finally diagnosed as having PE due to delayed-onset HIT because the HIT antibody was positive. When a patient develops thrombotic events during or after heparin therapy, the possibility of HIT should be considered...

..It is not clear whether tissue plasminogen activator (t-PA) thrombolysis in patients without major arterial occlusion is effective or safe...

..The aim of the study was to assess the correlation between OTT and early recanalization rate after IV-t-PA therapy...

..However, the time threshold of early recanalization for a favorable outcome remains unclear. The aim of this study was to assess patient outcome 3 months after t-PA therapy among patients with early, delayed and without recanalization...

..The aim of the present study is to investigate a method for determining the onset time of stroke in AIS patients within 24 hours (h) of onset...

..Most stroke patients with atrial fibrillation (AF) have elevated BNP levels. We investigated the relationships of plasma BNP levels before t-PA infusion and AF with early recanalization after t-PA infusion...

..We investigated whether the plasma brain natriuretic peptide (BNP) level on admission can serve as a biological marker of in-hospital death in patients with acute ischemic stroke...

..It is not known whether stroke patients with intracranial stenosis often have lower extremity atherosclerosis. The aim of our study was to elucidate this issue...

..The present study investigated early recanalization rate of major occluded arteries after tissue plasminogen activator (t-PA) infusion using serial magnetic resonance angiography (MRA) studies...

..However, we have sometimes observed dramatic recovery in patients with ICA occlusion after t-PA therapy. The aim of the present study was to investigate the mechanism of dramatic recovery in such patients...

..Patients with unknown onset time would be able to receive intravenous thrombolysis when showing diffusion-weighted imaging (DWI)/fluid-attenuated inversion recovery (FLAIR) mismatch...

..However, it has been unclear whether asymptomatic intracranial hemorrhage has clinical implications...

..The mechanism of TIA was diagnosed as paradoxical embolism, and we suspect that the cause of the TIA was associated with HCV-related type II mixed cryoglobulinemia...

..It is unclear whether hyperglycemia on admission in patients with acute intracerebral hemorrhage (ICH) increases the risk of early death...

..Intravenous administration of tissue plasminogen activator (t-PA) dissolves the clot and can improve clinical outcome in patients with acute ischemic stroke. However, lack of early recanalization frequently does not result in good outcome...

..The mechanism of neurological deterioration in small vessel disease is unclear. We examined the relationship between neurological deterioration and change of infarct volume in acute small vessel disease...

..The most important complication of t-PA therapy is intracerebral hemorrhage (ICH). The aim of this study was to use serial MRI studies to identify independent predictors of symptomatic and asymptomatic ICH after t-PA therapy...

..In a patient with paradoxical brain embolism associated with PE, c-TCD may be useful for both diagnosis of the presence of right-to-left shunting and evaluation of cardio-pulmonary circulation...

..We investigated the frequency of new lesions on diffusion-weighted imaging (DWI) after conventional cerebral angiography (CAG) in acute stroke patients and associated factors...

..By the end of follow-up MRI examination, his neurological deficits had completely disappeared. We report here the patient with transient ischemic attack with a reversible ischemic lesion on DWI without early arterial recanalization...

..No other embolic sources were identified in the carotid artery, aortic arch, or heart. We report herein a case of CRAO caused by paradoxical brain embolism...

..Therefore, the mechanism of TIA was diagnosed as paradoxical embolism. To the best of our knowledge, this is the first case report of paradoxical embolism in a patient with KTS...

..The aim of this study was to determine whether the association between HG and infarct volume expansion is dependent on collateral circulation...

..CONCLUSIONS: The first impression of patients and bystanders at stroke onset is important in order to reach hospital earlier in Japan. Public educational systems such as those, which advertise stroke warning signs, are necessary...

..001). The patients with both D-dimer >or=1.3 ng/dl and Hb <12.8 g/dl more frequently had occult malignancy than patients without (p = 0.0088)...

..026). TCD monitoring for 1 h during IV rt-PA can diagnose the recanalization based on MRA. TCD monitoring should predict good clinical outcome at three months...

..Finally we considered the stroke mechanism of this case as hemodynamic stroke based on TCD findings. Serial TCD examinations are useful to identify the hemodynamic mechanism of stroke in such case...

..The present study investigated the factors related to neurological deterioration in pontine infarction...

..However, the diagnostic accuracy of c-TCD for patent foramen ovale (PFO) remains uncertain. We investigated the relationship between the size of PFO determined by c-TEE and c-TCD findings and assessed the detectable rate of RLS by c-TCD...

..Recently, mobile aortic plaques (MAPs) have been proposed as embolic sources. However, the clinical characteristics of patients with MAPs are unclear...

..This is the first case of pontine infarction presenting with conjugate deviation in which unilateral conjugate gaze palsy and DWI could confirm the pathological lesion...

..We report here this case of autoimmune thyroid disease presenting as PRES...

..Therefore, we believed that ICA occlusion caused the infarcts in the territories of both the PCA and the anterior choroidal artery. This is a rare stroke case involving the territories of both the PCA and the anterior choroidal artery...

..4; 95% CI, 2.7 to 410.8; P=0.0062). CONCLUSIONS: DWI ASPECTS appears to be a reliable tool for predicting bad outcome. Patients with a DWI ASPECTS > 5 should be considered eligible for tissue plasminogen activator therapy...

..We studied safety and recanalization/recovery in patients older than 80 years treated with TPA and compared them with younger stroke patients...

..A T2* -weighted image and a FLAIR image disclosed edema surrounding the hematoma in the medial medullary lesion. T2* weighted images are useful for diagnosing and evaluating serial changes of medullary hemorrhage...

..Our goal was to apply this technology to initially characterize emboli detected during carotid stenting with distal protection...

..CONCLUSIONS: Bedside neurovascular ultrasound examination, combining carotid/vertebral duplex with TCD yields a substantial proportion of LAITs in excellent agreement with urgent DSA...

..We report here, that PCA may occur even in a normal pregnant woman who was given no medication, and should be considered in the diagnosis of postpartum cerebral vascular diseases in women...

..Immediately she was treated with methylprednisolone intravenously, and the angioedema improved. Orolingual angioedema should be considered as a complication associated with alteplase in a patient who has taking ACE inhibitor...