Katsutoshi Ara

Summary

Affiliation: Kao Corporation
Country: Japan

Publications

  1. ncbi request reprint Foot odor due to microbial metabolism and its control
    Katsutoshi Ara
    Biological Science Laboratories, Kao Co, Ltd, Tochigi 321 3497, Japan
    Can J Microbiol 52:357-64. 2006
  2. ncbi request reprint Bacillus minimum genome factory: effective utilization of microbial genome information
    Katsutoshi Ara
    Biological Science Laboratories, Kao Co, Ltd, 2606 Akabane, Ichikaimachi, Haga, Tochigi 321 3497, Japan
    Biotechnol Appl Biochem 46:169-78. 2007
  3. pmc Combined effect of improved cell yield and increased specific productivity enhances recombinant enzyme production in genome-reduced Bacillus subtilis strain MGB874
    Kenji Manabe
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    Appl Environ Microbiol 77:8370-81. 2011
  4. pmc Enhanced recombinant protein productivity by genome reduction in Bacillus subtilis
    Takuya Morimoto
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    DNA Res 15:73-81. 2008
  5. pmc Improved production of secreted heterologous enzyme in Bacillus subtilis strain MGB874 via modification of glutamate metabolism and growth conditions
    Kenji Manabe
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    Microb Cell Fact 12:18. 2013
  6. ncbi request reprint Bacillus subtilis AprX involved in degradation of a heterologous protein during the late stationary growth phase
    Takeko Kodama
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    J Biosci Bioeng 104:135-43. 2007
  7. pmc High external pH enables more efficient secretion of alkaline α-amylase AmyK38 by Bacillus subtilis
    Kenji Manabe
    Biological Science Laboratories, Kao Corporation, 2606 Akabane Ichikai, Haga, Tochigi 321 3497, Japan
    Microb Cell Fact 11:74. 2012
  8. ncbi request reprint A novel small protein of Bacillus subtilis involved in spore germination and spore coat assembly
    Takeko Kodama
    Biological Science Laboratories, Kao Corporation, Ichikai, Haga, Tochigi, Japan
    Biosci Biotechnol Biochem 75:1119-28. 2011
  9. ncbi request reprint Effect of Bacillus subtilis spo0A mutation on cell wall lytic enzymes and extracellular proteases, and prevention of cell lysis
    Takeko Kodama
    Tochigi Research Laboratories of Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    J Biosci Bioeng 103:13-21. 2007
  10. doi request reprint Introduction of marker-free deletions in Bacillus subtilis using the AraR repressor and the ara promoter
    Shenghao Liu
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Tochigi 321 3497, Japan
    Microbiology 154:2562-70. 2008

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Foot odor due to microbial metabolism and its control
    Katsutoshi Ara
    Biological Science Laboratories, Kao Co, Ltd, Tochigi 321 3497, Japan
    Can J Microbiol 52:357-64. 2006
    ..As a result, we identified citral, citronellal, and geraniol as fragrant agents that inhibit the generation of isovaleric acid at low concentrations...
  2. ncbi request reprint Bacillus minimum genome factory: effective utilization of microbial genome information
    Katsutoshi Ara
    Biological Science Laboratories, Kao Co, Ltd, 2606 Akabane, Ichikaimachi, Haga, Tochigi 321 3497, Japan
    Biotechnol Appl Biochem 46:169-78. 2007
    ..subtilis 168 strain, thus demonstrating that genome reduction does not contribute to a negative influence on enzyme productivity...
  3. pmc Combined effect of improved cell yield and increased specific productivity enhances recombinant enzyme production in genome-reduced Bacillus subtilis strain MGB874
    Kenji Manabe
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    Appl Environ Microbiol 77:8370-81. 2011
    ..Our findings represent a good starting point for the further improvement of B. subtilis reduced-genome strains as cell factories for the production of heterologous enzymes...
  4. pmc Enhanced recombinant protein productivity by genome reduction in Bacillus subtilis
    Takuya Morimoto
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    DNA Res 15:73-81. 2008
    ..subtilis cells as hosts of industrial protein production...
  5. pmc Improved production of secreted heterologous enzyme in Bacillus subtilis strain MGB874 via modification of glutamate metabolism and growth conditions
    Kenji Manabe
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    Microb Cell Fact 12:18. 2013
    ..However, deletion of rocG dramatically decreased production of the alkaline cellulase Egl-237 in strain MGB874 (strain 874∆rocG)...
  6. ncbi request reprint Bacillus subtilis AprX involved in degradation of a heterologous protein during the late stationary growth phase
    Takeko Kodama
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    J Biosci Bioeng 104:135-43. 2007
    ..In addition, we showed the degradation of the heterologous protein by AprX that leaked to the culture medium (probably caused by cell lysis) during the late stationary growth phase...
  7. pmc High external pH enables more efficient secretion of alkaline α-amylase AmyK38 by Bacillus subtilis
    Kenji Manabe
    Biological Science Laboratories, Kao Corporation, 2606 Akabane Ichikai, Haga, Tochigi 321 3497, Japan
    Microb Cell Fact 11:74. 2012
    ..Here, we investigated the suitability of strain MGB874 for the production of α-amylase, which was anticipated to provoke secretion stress responses involving the CssRS (Control secretion stress Regulator and Sensor) system...
  8. ncbi request reprint A novel small protein of Bacillus subtilis involved in spore germination and spore coat assembly
    Takeko Kodama
    Biological Science Laboratories, Kao Corporation, Ichikai, Haga, Tochigi, Japan
    Biosci Biotechnol Biochem 75:1119-28. 2011
    ..It appears that SscA is a novel spore protein involved in the assembly of several components of the spore coat, including CotB, CotG, and CotH, and is associated with spore germination...
  9. ncbi request reprint Effect of Bacillus subtilis spo0A mutation on cell wall lytic enzymes and extracellular proteases, and prevention of cell lysis
    Takeko Kodama
    Tochigi Research Laboratories of Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321 3497, Japan
    J Biosci Bioeng 103:13-21. 2007
    ..The introduction of a major autolysin and/or SigD mutations into the spo0A mutant was effective for preventing cell lysis...
  10. doi request reprint Introduction of marker-free deletions in Bacillus subtilis using the AraR repressor and the ara promoter
    Shenghao Liu
    Biological Science Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Tochigi 321 3497, Japan
    Microbiology 154:2562-70. 2008
    ..8 kb hutM-csbC region have been efficiently and successfully deleted, without leaving markers in the target loci. The positive selection and simple procedure will make it a useful tool for the construction of multiple mutations...
  11. doi request reprint Enhanced extracellular production of heterologous proteins in Bacillus subtilis by deleting the C-terminal region of the SecA secretory machinery
    Hiroshi Kakeshita
    Graduate School of Life and Environmental Sciences, University of Tsukuba, 1 1 1 Tennoudai, Tsukuba, Ibaraki, 305 8572, Japan
    Mol Biotechnol 46:250-7. 2010
    ..This study provides a useful method to enhance the extracellular production of heterologous proteins in B. subtilis...
  12. ncbi request reprint Extracellular production of human cystatin S and cystatin SA by Bacillus subtilis
    Shunichi Akiba
    Biological Science Laboratories of Kao Corporation, 2606 Akabane, Ichikai, Tochigi 321 3497, Japan
    Protein Expr Purif 49:203-10. 2006
    ..We conclude that this system has high utility for expression of commercial quantities of secreted proteins...
  13. ncbi request reprint The accurate replacement of long genome region more than several hundreds kilobases in Bacillus subtilis
    Shenghao Liu
    Biological Science Laboratories, Kao Corporation
    Genes Genet Syst 82:9-19. 2007
    ..Using this method, the 99 kb yxjG-yxbA region, the 249 kb pbpG-yxbA region and the 602 kb yvfT-yxbA region were suggested to be replaced continuously and accurately...