K Nobuhara

Summary

Affiliation: Kansai Medical University
Country: Japan

Publications

  1. pmc Frontal white matter anisotropy and symptom severity of late-life depression: a magnetic resonance diffusion tensor imaging study
    K Nobuhara
    Department of Neuropsychiatry, Kansai Medical University, Moriguchi, Japan
    J Neurol Neurosurg Psychiatry 77:120-2. 2006
  2. ncbi request reprint SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP
    K Nobuhara
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Hospital, Stockholm, Sweden
    Eur J Nucl Med 28:13-24. 2001
  3. ncbi request reprint Successful electroconvulsive treatment of depression associated with a marked reduction in the symptoms of tardive dyskinesia
    Kenji Nobuhara
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    J ECT 20:262-3. 2004
  4. ncbi request reprint Effects of electroconvulsive therapy on frontal white matter in late-life depression: a diffusion tensor imaging study
    K Nobuhara
    Department of Neuropsychiatry, Kansai Medical University, Moriguchi City, Japan
    Neuropsychobiology 50:48-53. 2004
  5. ncbi request reprint Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer's disease
    K Nobuhara
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    Psychopharmacology (Berl) 149:45-55. 2000
  6. ncbi request reprint Diffusion tensor magnetic resonance imaging of disruption of regional white matter in schizophrenia
    T Minami
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 47:141-5. 2003
  7. ncbi request reprint Effectiveness of treatment with donepezil hydrochloride and changes in regional cerebral blood flow in patients with Alzheimer's disease
    Tsunetaka Yoshida
    Department of Radiology, Kansai Medical University, Moriguchi, Osaka, Japan
    Ann Nucl Med 21:257-65. 2007
  8. doi request reprint Corpus callosum in patients with obsessive-compulsive disorder: diffusion-tensor imaging study
    Yukiko Saito
    Department of Neuropsychiatry, Kansai Medical University, 10 15 Fumizono cho, Moriguchi City, Osaka, 570 8506, Japan
    Radiology 246:536-42. 2008
  9. ncbi request reprint Increased omega complexity and decreased microstate duration in nonmedicated schizophrenic patients
    Satoshi Irisawa
    Department of Neuropsychiatry, Kansai Medical University, 10 15 Fumizono cho, Moriguchi 570 8506, Japan
    Neuropsychobiology 54:134-9. 2006
  10. ncbi request reprint Neural disorganization in the superior cerebellar peduncle and cognitive abnormality in patients with schizophrenia: A diffusion tensor imaging study
    Gaku Okugawa
    Department of Neuropsychiatry, Kansai Medical University, 10 15 Fumizonocho Moriguchi, Osaka 570 8506, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:1408-12. 2006

Collaborators

Detail Information

Publications21

  1. pmc Frontal white matter anisotropy and symptom severity of late-life depression: a magnetic resonance diffusion tensor imaging study
    K Nobuhara
    Department of Neuropsychiatry, Kansai Medical University, Moriguchi, Japan
    J Neurol Neurosurg Psychiatry 77:120-2. 2006
    ....
  2. ncbi request reprint SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP
    K Nobuhara
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Hospital, Stockholm, Sweden
    Eur J Nucl Med 28:13-24. 2001
    ..123I]Z-IQNP has potential for exploration of M2 receptor binding in the cerebellum...
  3. ncbi request reprint Successful electroconvulsive treatment of depression associated with a marked reduction in the symptoms of tardive dyskinesia
    Kenji Nobuhara
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    J ECT 20:262-3. 2004
    ..We discuss the possibility of improving TD by treating the depression with ECT...
  4. ncbi request reprint Effects of electroconvulsive therapy on frontal white matter in late-life depression: a diffusion tensor imaging study
    K Nobuhara
    Department of Neuropsychiatry, Kansai Medical University, Moriguchi City, Japan
    Neuropsychobiology 50:48-53. 2004
    ..A course of bilateral ECT ameliorated white matter integrity in frontal brain regions. This suggests a strong relationship with the antidepressant action of ECT...
  5. ncbi request reprint Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer's disease
    K Nobuhara
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    Psychopharmacology (Berl) 149:45-55. 2000
    ..Z-(R,R)-1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo1-propen-3-yl)-alpha-phenylacetat e (Z-IQNP) is a muscarinic antagonist with high affinity for the M2 subtype...
  6. ncbi request reprint Diffusion tensor magnetic resonance imaging of disruption of regional white matter in schizophrenia
    T Minami
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 47:141-5. 2003
    ..Our findings also show the effects of antipsychotics on the white matter in the left frontal region in schizophrenia...
  7. ncbi request reprint Effectiveness of treatment with donepezil hydrochloride and changes in regional cerebral blood flow in patients with Alzheimer's disease
    Tsunetaka Yoshida
    Department of Radiology, Kansai Medical University, Moriguchi, Osaka, Japan
    Ann Nucl Med 21:257-65. 2007
    ....
  8. doi request reprint Corpus callosum in patients with obsessive-compulsive disorder: diffusion-tensor imaging study
    Yukiko Saito
    Department of Neuropsychiatry, Kansai Medical University, 10 15 Fumizono cho, Moriguchi City, Osaka, 570 8506, Japan
    Radiology 246:536-42. 2008
    ....
  9. ncbi request reprint Increased omega complexity and decreased microstate duration in nonmedicated schizophrenic patients
    Satoshi Irisawa
    Department of Neuropsychiatry, Kansai Medical University, 10 15 Fumizono cho, Moriguchi 570 8506, Japan
    Neuropsychobiology 54:134-9. 2006
    ..These results indicated looser cooperativity, or decreased connectivity of the active brain process and deviant brain information processing in schizophrenic patients...
  10. ncbi request reprint Neural disorganization in the superior cerebellar peduncle and cognitive abnormality in patients with schizophrenia: A diffusion tensor imaging study
    Gaku Okugawa
    Department of Neuropsychiatry, Kansai Medical University, 10 15 Fumizonocho Moriguchi, Osaka 570 8506, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:1408-12. 2006
    ..These findings suggest that there is neural disruption in the superior cerebellar peduncle in patients with schizophrenia, which may be involved in the cognitive abnormalities found in schizophrenia...
  11. ncbi request reprint Olanzapine increases grey and white matter volumes in the caudate nucleus of patients with schizophrenia
    Gaku Okugawa
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 55:43-6. 2007
    ..These findings suggest that treatment with olanzapine may increase the grey and white matter volumes in the caudate nucleus in patients with schizophrenia...
  12. ncbi request reprint Diffusion tensor imaging study of the middle cerebellar peduncles in patients with schizophrenia
    Gaku Okugawa
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Cerebellum 4:123-7. 2005
    ..This review provides current findings regarding DTI study on the cerebellar peduncle in patients with schizophrenia...
  13. ncbi request reprint Controlled clinical comparison of paroxetine and fluvoxamine considering the serotonin transporter promoter polymorphism
    Masaki Kato
    Department of Neuropsychiatry, Kansai Medical University, Moriguchi, Osaka, Japan
    Int Clin Psychopharmacol 20:151-6. 2005
    ..These findings suggest that the genetic test may be useful in investigating the efficacy of the two SSRIs, and that normalization by the 5HTTLPR genotypes may lead to improvement of the precision of comparative analysis...
  14. ncbi request reprint Reduced white matter volume of the caudate nucleus in patients with schizophrenia
    Katsunori Takase
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 50:296-300. 2004
    ..Our result replicates a previous study reporting that there is a lack of negative correlation between age and caudate nucleus volume. We also suggest that the disease process of schizophrenia might interfere with normal aging...
  15. ncbi request reprint Subtle disruption of the middle cerebellar peduncles in patients with schizophrenia
    Gaku Okugawa
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 50:119-23. 2004
    ..The findings of the study suggest that antipsychotics may improve the subtle disruption in the middle cerebellar peduncles in patients with schizophrenia...
  16. ncbi request reprint Global approach to multichannel electroencephalogram analysis for diagnosis and clinical evaluation in mild Alzheimer's disease
    Masafumi Yoshimura
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 49:163-6. 2004
    ..These results indicate an increase in spatial complexity of the brain electric field in mild AD, as well as a close relationship between slowing of the global frequency of field changes and the cognitive decline in mild AD...
  17. ncbi request reprint Inter- and intraoperator reliability of brain tissue measures using magnetic resonance imaging
    Gaku Okugawa
    Dept of Neuropsychiatry, Kansai Medical University, 10 15 Fumizonocho Moriguchi, Osaka 570 8506, Japan
    Eur Arch Psychiatry Clin Neurosci 253:301-6. 2003
    ..971 and 0.999. The segmentation and measurement are useful for volumetric studies in the human brain using BRAINS...
  18. doi request reprint Cerebellar posterior superior vermis and cognitive cluster scores in drug-naive patients with first-episode schizophrenia
    Gaku Okugawa
    Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan
    Neuropsychobiology 56:216-9. 2007
    ..Smaller volumes of the posterior superior vermis were associated with worse cognitive cluster scores in patients with first-episode schizophrenia...
  19. ncbi request reprint Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
    Masaki Kato
    Department of Neuropsychiatry, Kansai Medical University, Moriguchi, Japan
    Neuropsychobiology 53:186-95. 2006
    ..Furthermore, the effects of these polymorphisms varied from one SSRI to another and thus may depend on the characteristics of each SSRI...
  20. ncbi request reprint Perospirone for treatment of dissociative identity disorder
    Gaku Okugawa
    Psychiatry Clin Neurosci 59:624. 2005
  21. ncbi request reprint Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET
    Victor W Pike
    MRC Cyclotron Unit, Imperial College School of Medicine, Hammersmith Hospital, DuCane Road, W12 0NN, London, UK
    Eur J Nucl Med Mol Imaging 30:1520-8. 2003
    ..Radioactivity in all brain regions was reduced almost to the level in cerebellum by 176 min after radioligand injection. These findings show that [(123)I]SB 207710 is an effective radioligand for imaging brain 5-HT(4) receptors in vivo...