Yasuhiro Matsumura

Summary

Affiliation: Kansai Medical University
Country: Japan

Publications

  1. ncbi Toxic effects of ultraviolet radiation on the skin
    Yasuhiro Matsumura
    Department of Dermatology, Kansai Medical University, Osaka 570 8507, Japan
    Toxicol Appl Pharmacol 195:298-308. 2004
  2. ncbi PIG7/LITAF gene mutation and overexpression of its gene product in extramammary Paget's disease
    Yasuhiro Matsumura
    Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int J Cancer 111:218-23. 2004
  3. ncbi Inverse relationship between increased apoptosis and decreased skin cancer in UV-irradiated CD1d-/- mice
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Photochem Photobiol 81:46-51. 2005
  4. ncbi Development of a new mouse model (xeroderma pigmentosum a-deficient, stem cell factor-transgenic) of ultraviolet B-induced melanoma
    Fumikazu Yamazaki
    Department of Dermatology, Kansai Medical University, Moriguchi, Osaka, Japan
    J Invest Dermatol 125:521-5. 2005
  5. pmc Resistance of CD1d-/- mice to ultraviolet-induced skin cancer is associated with increased apoptosis
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, Houston, TX, 77030, USA
    Am J Pathol 165:879-87. 2004
  6. ncbi Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 178, Houston, TX 77030, USA
    Expert Rev Mol Med 4:1-22. 2002
  7. ncbi Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type
    Miki Tanioka
    Department of Dermatology, Graduate School of Medicine, Kobe University, Kobe, Japan
    J Invest Dermatol 127:1745-51. 2007
  8. ncbi XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis
    Fumikazu Yamazaki
    Department of Dermatology, Kansai Medical University, Moriguchi, Osaka, Japan
    J Invest Dermatol 123:220-8. 2004
  9. ncbi Molecular mechanisms of photocarcinogenesis
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 178, Houston, TX, 77030, USA
    Front Biosci 7:d765-83. 2002
  10. doi Hypertension-susceptibility gene prevalence in the Pacific Islands and associations with hypertension in Melanesia
    Takuro Furusawa
    Graduate School of Asian and African Area Studies, Kyoto University, Kyoto, Japan
    J Hum Genet 58:142-9. 2013

Collaborators

  • HONNAVARA ANANTHASWAMY
  • Takeshi Horio
  • Fumikazu Yamazaki
  • Chikako Nishigori
  • Jun Ohashi
  • Takuro Furusawa
  • Izumi Naka
  • Ryosuke Kimura
  • Stephen Ullrich
  • Kazuhiko Aoyagi
  • Su Ryang Kim
  • P Wolf
  • Hisayuki Matsushita
  • Shigeki Onouchi
  • Takako Eguchi Nakajima
  • Satoshi Yajima
  • Miki Tanioka
  • Takashi Minowa
  • Sayuri Nomura
  • Nobuhiro Nishiyama
  • Kuniaki Shirao
  • Tetsuya Hamaguchi
  • Yasuhide Yamada
  • Ken Kato
  • Masahiro Yasunaga
  • Fumiaki Koizumi
  • Yasuhiko Kano
  • Yasuhiro Shimada
  • Ryusuke Ono
  • Hiroki Inui
  • Eriko Otoshi-Honda
  • Tohru Nagano
  • Teruhiko Yoshida
  • Yoshiki Miyachi
  • Kazuhiko Yoshimatsu
  • Shinichi Moriwaki
  • Nobuko Yamamoto
  • Taro Masaki
  • Hironori Kaneko
  • Mie Ishii
  • Hiroki Sasaki
  • Masahiro Takigawa
  • Tatsuo Teramoto
  • Takahiro Kozu
  • Takayuki Akasu
  • Norio Saito
  • Tadao Kakizoe
  • Yoshihiro Moriya
  • Masanori Sugito
  • Seiichiro Yamamoto
  • Masaaki Ito
  • Hiroyuki Tsunoda
  • Shin Fujita
  • Yukio Kato
  • Horacio Cabral
  • Yuichi Sugiyama
  • Souichiro Okazaki
  • Kazunori Kataoka
  • Kazuto Nishio
  • Masaki Miyamoto

Detail Information

Publications17

  1. ncbi Toxic effects of ultraviolet radiation on the skin
    Yasuhiro Matsumura
    Department of Dermatology, Kansai Medical University, Osaka 570 8507, Japan
    Toxicol Appl Pharmacol 195:298-308. 2004
    ..Although such therapy is beneficial, it is accompanied with undesirable side effects. Thus, UV radiation is like two sides of the same coin--on one side, it has detrimental effects, and on the other side, it has beneficial effects...
  2. ncbi PIG7/LITAF gene mutation and overexpression of its gene product in extramammary Paget's disease
    Yasuhiro Matsumura
    Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Int J Cancer 111:218-23. 2004
    ..PIG7/LITAF mRNA expression is confined to tumor cells in in situ mRNA hybridization analysis. These results indicate that genetic disorder and overexpression of PIG7/LITAF may be involved in EMPD carcinogenesis...
  3. ncbi Inverse relationship between increased apoptosis and decreased skin cancer in UV-irradiated CD1d-/- mice
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Photochem Photobiol 81:46-51. 2005
    ..These results indicate that the resistance of CD1d-/- mice to UV carcinogenesis may be due to increased cell death and elimination of keratinocytes and fibroblasts containing DNA damage and p53 mutations...
  4. ncbi Development of a new mouse model (xeroderma pigmentosum a-deficient, stem cell factor-transgenic) of ultraviolet B-induced melanoma
    Fumikazu Yamazaki
    Department of Dermatology, Kansai Medical University, Moriguchi, Osaka, Japan
    J Invest Dermatol 125:521-5. 2005
    ..The newly generated model mouse might be useful for studying the photobiological aspects of human melanoma, because the mice developed melanoma from epidermal melanocytes only after UVR exposures...
  5. pmc Resistance of CD1d-/- mice to ultraviolet-induced skin cancer is associated with increased apoptosis
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, Houston, TX, 77030, USA
    Am J Pathol 165:879-87. 2004
    ..Our findings identify an unexpected and novel function for CD1d as a critical molecule regulating UV carcinogenesis, by inhibiting apoptosis to prevent elimination of potentially malignant keratinocytes and fibroblasts...
  6. ncbi Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 178, Houston, TX 77030, USA
    Expert Rev Mol Med 4:1-22. 2002
    ..Further investigation and a better understanding of photocarcinogenesis are critical to the development of effective prevention and intervention strategies for human skin cancer...
  7. ncbi Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type
    Miki Tanioka
    Department of Dermatology, Graduate School of Medicine, Kobe University, Kobe, Japan
    J Invest Dermatol 127:1745-51. 2007
    ..Seven mutations in the POLH gene including three novel mutations were identified. Among the mutations detected, 11 alleles out of 28 (39%) were G490T mutations...
  8. ncbi XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis
    Fumikazu Yamazaki
    Department of Dermatology, Kansai Medical University, Moriguchi, Osaka, Japan
    J Invest Dermatol 123:220-8. 2004
    ..These findings indicate that epidermal melanin has a high ability to protect DNA damage by UVB radiation, and thereby, prevent UV-induced inflammation, immunosuppression, and carcinogenesis...
  9. ncbi Molecular mechanisms of photocarcinogenesis
    Yasuhiro Matsumura
    Department of Immunology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 178, Houston, TX, 77030, USA
    Front Biosci 7:d765-83. 2002
    ..The understanding and further investigation of photocarcinogenesis is critical to the development of effective prevention and intervention strategies for human skin cancer...
  10. doi Hypertension-susceptibility gene prevalence in the Pacific Islands and associations with hypertension in Melanesia
    Takuro Furusawa
    Graduate School of Asian and African Area Studies, Kyoto University, Kyoto, Japan
    J Hum Genet 58:142-9. 2013
    ..Although other polymorphisms associated with hypertension and additional populations remain to be studied, these findings suggest that the Pacific Islanders' susceptibility to hypertension arose because of human migration and adaptation...
  11. ncbi Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer
    Satoshi Yajima
    Genetics Division, National Cancer Center Research Institute, Tsukiji 5 1 1, Chuo Ku, Tokyo 104 0045, Japan
    Int J Oncol 31:1029-37. 2007
    ..Our extensive gene list provides other markers for fecal RNA-based colorectal cancer screening...
  12. ncbi A new method for isolating colonocytes from naturally evacuated feces and its clinical application to colorectal cancer diagnosis
    Hisayuki Matsushita
    Investigative Treatment Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Gastroenterology 129:1918-27. 2005
    ....
  13. pmc Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis
    Peter Wolf
    Research Unit for Photodermatology, Department of Dermatology, Medical University Graz, Auenbrugger Platz 8, A 8036 Graz, Austria
    Am J Pathol 169:795-805. 2006
    ....
  14. ncbi Fourteen novel genetic variations and haplotype structures of the TYMS gene encoding human thymidylate synthase (TS)
    Su Ryang Kim
    Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan
    Drug Metab Pharmacokinet 21:509-16. 2006
    ..In Blocks 1 and 3, 7 and 19 haplotypes were determined/inferred, respectively. Our findings provide fundamental and useful information for genotyping TYMS in the Japanese and probably other Asian populations...
  15. ncbi Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice
    Nobuhiro Nishiyama
    Department of Materials Science and Engineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
    Cancer Res 63:8977-83. 2003
    ..These data suggest that CDDP/m could be a promising formulation of CDDP for the targeted therapy of solid tumors...
  16. ncbi PCR-based assessment of the recovery rate of exfoliated colonocytes or cancer cells from fecal samples depends on the storage conditions after defecation
    Shigeki Onouchi
    Investigative Treatment Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Japan
    J Gastrointestin Liver Dis 16:369-72. 2007
    ..The purpose of the present study was to determine how long after defecation and at what temperature the fecal samples should be stored to isolate the colonocytes successfully...
  17. doi Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil
    Takako Eguchi Nakajima
    Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan
    Int J Cancer 122:2148-53. 2008
    ..Optimal therapeutic synergy was observed between NK012 and 5FU, therefore, this regimen is considered to hold promise of clinical benefit, especially for patients with colorectal cancer...