Kazunari Kaneko

Summary

Affiliation: Kansai Medical University
Country: Japan

Publications

  1. pmc Impact of obesity on childhood kidney
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University
    Pediatr Rep 3:e27. 2011
  2. pmc Urinary sludge caused by ceftriaxone in a young boy
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University
    Pediatr Rep 4:e14. 2012
  3. doi request reprint Measurement of urinary 8-oxo-7,8-dihydro-2-deoxyguanosine in a novel point-of-care testing device to assess oxidative stress in children
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Clin Chim Acta 413:1822-6. 2012
  4. doi request reprint Intravenous immunoglobulin counteracts oxidative stress in Kawasaki disease
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 l Shin machi, Hirakata shi, Osaka, 573 1191, Japan
    Pediatr Cardiol 33:1086-8. 2012
  5. doi request reprint Serum albumin level accurately reflects antioxidant potentials in idiopathic nephrotic syndrome
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Hirakata, Osaka, Japan
    Clin Exp Nephrol 16:411-4. 2012
  6. doi request reprint Treatment for nocturnal enuresis: the current state in Japan
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Int 54:8-13. 2012
  7. doi request reprint A family with X-linked benign familial hematuria
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 25:545-8. 2010
  8. ncbi request reprint Oxidative imbalance in idiopathic renal hypouricemia
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 24:869-71. 2009
  9. doi request reprint Prediction of the risk of coronary arterial lesions in Kawasaki disease by brain natriuretic peptide
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Cardiol 32:1106-9. 2011
  10. doi request reprint Immunoglobulin preparations affect hyponatremia in Kawasaki disease
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 l Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Eur J Pediatr 169:957-60. 2010

Collaborators

Detail Information

Publications67

  1. pmc Impact of obesity on childhood kidney
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University
    Pediatr Rep 3:e27. 2011
    ..BMI and systolic BP (mmHg) were significantly higher in the former than in the latter. As a result, obesity may be associated with the development of renal injury even in childhood...
  2. pmc Urinary sludge caused by ceftriaxone in a young boy
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University
    Pediatr Rep 4:e14. 2012
    ..It is therefore worthwhile to monitor the levels of urinary calcium to creatinine ratio in patients on ceftriaxone, as they may be at greater risk for developing large stones and renal damage...
  3. doi request reprint Measurement of urinary 8-oxo-7,8-dihydro-2-deoxyguanosine in a novel point-of-care testing device to assess oxidative stress in children
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Clin Chim Acta 413:1822-6. 2012
    ..Ltd., Japan) has been developed for point-of-care testing (POCT) to measure urinary 8-oxodG. We verified the reliability of the value of urinary 8-oxodG measured by this novel analyzer and to set the age-related reference intervals...
  4. doi request reprint Intravenous immunoglobulin counteracts oxidative stress in Kawasaki disease
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 l Shin machi, Hirakata shi, Osaka, 573 1191, Japan
    Pediatr Cardiol 33:1086-8. 2012
    ..Further study to elucidate this point would be worthwhile...
  5. doi request reprint Serum albumin level accurately reflects antioxidant potentials in idiopathic nephrotic syndrome
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Hirakata, Osaka, Japan
    Clin Exp Nephrol 16:411-4. 2012
    ..This study was conducted to investigate whether hypoalbuminemia contributes to a decreased biological antioxidant potentials (BAP) in idiopathic nephrotic syndrome (INS)...
  6. doi request reprint Treatment for nocturnal enuresis: the current state in Japan
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Int 54:8-13. 2012
    ....
  7. doi request reprint A family with X-linked benign familial hematuria
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 25:545-8. 2010
    ..e. X-linked Alport syndrome or benign familial hematuria, remains unknown...
  8. ncbi request reprint Oxidative imbalance in idiopathic renal hypouricemia
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 24:869-71. 2009
    ..Antioxidant properties may alter this imbalance by augmenting the antioxidant activity...
  9. doi request reprint Prediction of the risk of coronary arterial lesions in Kawasaki disease by brain natriuretic peptide
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Cardiol 32:1106-9. 2011
    ..4. In conclusion, NT-proBNP is increased in KD patients who are developing CAL, and patients with an elevated serum NT-proBNP >1,000 pg/ml have a risk of CAL ~10 times higher than that of patients with a modest increase...
  10. doi request reprint Immunoglobulin preparations affect hyponatremia in Kawasaki disease
    Kazunari Kaneko
    Department of Pediatrics, Kansai Medical University, 2 3 l Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Eur J Pediatr 169:957-60. 2010
    ..In conclusion, we should keep it in mind that the IVIG products without Na have an adverse affect on hyponatremia in KD though their efficacy seems to be equivalent to those containing high Na...
  11. doi request reprint A novel nuclear factor κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates puromycin aminonucleoside-induced nephrosis in mice
    Tomohiko Shimo
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Am J Nephrol 37:302-9. 2013
    ..We conducted this study to ask whether DHMEQ may ameliorate the nephrosis in mice induced by puromycin aminonucleoside (PAN), which is considered to be an animal model for MCNS...
  12. doi request reprint Low calcium diet increases radical production of polymorphonuclear leukocytes from mice
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi Shi, Osaka, Japan
    Int J Vitam Nutr Res 79:375-80. 2009
    ..aureus-stimulated PMNs. A low-calcium diet increases ROS production from stimulated PMNs and decreases NO production at baseline. This finding suggests that calcium regulates ROS production from PMNs...
  13. ncbi request reprint A calcium-deficient diet in pregnant, nursing rats induces hypomethylation of specific cytosines in the 11β-hydroxysteroid dehydrogenase-1 promoter in pup liver
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi, Osaka 570 8506, Japan Electronic address
    Nutr Res 33:961-70. 2013
    ..These findings indicated that prenatal nutrition affected glucocorticoid metabolism in offspring in part by affecting the epigenome of offspring. ..
  14. ncbi request reprint GSTT1 gene abnormality in minimal change nephrotic syndrome with elevated serum immunoglobulin E
    Kohei Miyazaki
    Department of Pediatrics, Kinki University School of Medicine, Osaka, Japan
    Clin Nephrol 77:261-6. 2012
    ..Imbalance between T-helper 1 (Th1) and 2 (Th2) lymphocytes and effects of reactive oxygen species (ROS) upon glomerular capillary walls have been implicated in minimal change nephrotic syndrome (MCNS)...
  15. pmc B-type natriuretic peptide for assessment of haemodynamically significant patent ductus arteriosus in premature infants
    Kenji Mine
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Acta Paediatr 102:e347-52. 2013
    ..This study was conducted to explore whether the blood BNP can be a valuable biomarker to assess the necessity of treatment for hsPDA in premature infants...
  16. doi request reprint Close association between proteinuria and regulatory T cells in patients with idiopathic nephrotic syndrome
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka, 573 1191, Japan
    Pediatr Nephrol 28:667-9. 2013
    ..In contrast, there has been no case report suggesting an association between influenza B virus infection and the remission of INS...
  17. ncbi request reprint Voiding cystourethrography is mandatory in infants with febrile urinary tract infection
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University
    Tohoku J Exp Med 231:251-5. 2013
    ..7% and 52.9% in detecting VUR and in predicting renal scarring assessed by renal scintigraphy, respectively. In conclusion, VCUG should be performed in all infants after their first febrile UTIs. ..
  18. doi request reprint Steroid pulse therapy for children with intravenous immunoglobulin therapy-resistant Kawasaki disease: a prospective study
    Masayuki Teraguchi
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakatashi, Osaka, 573 1191, Japan
    Pediatr Cardiol 34:959-63. 2013
    ..MPT does not reduce the risk of development to CAL and does not seem to be beneficial as single agent therapy for IVIG resistant KD...
  19. doi request reprint N-terminal pro-brain natriuretic peptide and risk of coronary artery lesions and resistance to intravenous immunoglobulin in Kawasaki disease
    Ken Yoshimura
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    J Pediatr 162:1205-9. 2013
    ....
  20. ncbi request reprint Production of nitric oxide is lower in Shiga toxin-stimulated neutrophils of infants compared to those of children or adults
    Shoji Tsuji
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Tohoku J Exp Med 228:247-52. 2012
    ..These results suggest that NO may contribute to the cellular defense mechanisms against Stx...
  21. ncbi request reprint Increased production of nitric oxide by phagocytic stimulated neutrophils in patients with chronic granulomatous disease
    Shoji Tsuji
    Department of Pediatrics, Kansai Medical University, Hirakata shi, Osaka, Japan
    J Pediatr Hematol Oncol 34:500-2. 2012
    ....
  22. doi request reprint Hereditary renal hypouricemia: a cause of calcium oxalate urolithiasis in a young female
    Naoto Nishizaki
    Division of Nephrology, Saitama Children s Medical Center, Saitama, Japan
    Clin Nephrol 77:161-3. 2012
    ..To the best of our knowledge, this is the youngest case of hereditary renal hypouricemia caused by URAT1 gene mutation, which was found by hematuria due to calcium oxalate urolithiasis...
  23. ncbi request reprint Increased nitric oxide production by neutrophils in early stage of Kawasaki disease
    Ken Yoshimura
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Eur J Pediatr 168:1037-41. 2009
    ..Abnormal immune system in KD might be characterized by an overproduction of NO, whereas the role of NO in endothelial damage remains to be elucidated...
  24. ncbi request reprint Usefulness of an automated urinary flow cytometer in mass screening for nephritis
    Kazunari Kaneko
    Department of Pediatrics, Juntendo University Urayasu Hospital, 2 l l Tomioka, Urayasu shi, Chiba 279 0021, Japan
    Pediatr Nephrol 19:499-502. 2004
    ..It can precisely predict children with only transient hematuria who do not have any serious illness, and therefore can exclude further unnecessary examinations, resulting in the improvement of cost-effectiveness of the current program...
  25. doi request reprint Increased urinary calcium excretion caused by ceftriaxone: possible association with urolithiasis
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University, 2 3 l Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 27:605-9. 2012
    ..We therefore suggest that it is worthwhile monitoring the uCa/Cr levels in patients on ceftriaxone as they may be at greater risk for developing large stones and renal damage...
  26. doi request reprint Upregulation of hepatic 11β-hydroxysteroid dehydrogenase-1 expression in calcium-deficient rats
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi, Japan
    Ann Nutr Metab 59:73-8. 2011
    ..Many epidemiologic studies have reported a link between calcium (Ca) deficiency and metabolic syndrome. In this study, we examine Ca deficiency in rats and whether changes in glucocorticoid metabolism are induced...
  27. doi request reprint Diagnosis of autoimmune neutropenia by neutrophil-bound IgG and IgM antibodies
    Taichi Ito
    Department of Pediatrics, Kansai Medical University, Moriguchi Shi, Osaka, Japan
    J Pediatr Hematol Oncol 33:552-5. 2011
    ..997, respectively) in the diagnosis of AIN. D-GIFT detecting both neutrophil-bound IgG autoantibodies and IgM autoantibodies has discriminatory power for identifying patients with AIN and, therefore, can be a useful diagnostic test...
  28. doi request reprint Significance of twinkling artifact on ultrasound in the diagnosis of cystine urolithiasis
    Yoshimitsu Fujii
    Nakano Children s Hospital, Osaka, Japan
    Pediatr Int 55:e49-51. 2013
    ..Laparotomic stone removal was successfully conducted and the calculus was confirmed to be composed of cystine. The finding of TA upon US facilitates identification of the structure and location of the intra-abdominal mass...
  29. doi request reprint Down-regulation of hepatic phosphoenolpyruvate carboxykinase expression in magnesium-deficient rats
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Fumizono cho, Moriguchi Shi, Osaka, Japan
    Magnes Res 25:131-9. 2012
    ..Higher ADMA induces hypertension and insulin resistance. Hyperinsulinemia induces hepatic down-regulation of PEPCK, and is possibly a key mechanism inducing the metabolic complications of magnesium deficiency...
  30. doi request reprint Novel use of rituximab for steroid-dependent nephrotic syndrome in children
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Am J Nephrol 38:483-8. 2013
    ..This study was conducted to clarify whether the long-term remission of SDNS can be obtained by repeated RTX administrations...
  31. ncbi request reprint Different phenotypes of HNF1ß deletion mutants in familial multicystic dysplastic kidneys
    Masafumi Hasui
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Clin Nephrol 79:484-7. 2013
    ..Furthermore, the fact that no clear phenotype-genotype correlation exists suggests that gene(s) other than HNF1β are also involved in nephrogenesis and the development of MCDK...
  32. ncbi request reprint Effect of a novel free radical scavenger, edaravone, on puromycin aminonucleoside induced nephrosis in rats
    Tomonosuke Someya
    Department of Pediatrics, School of Medicine, Juntendo University, Tokyo, Japan
    Pediatr Nephrol 20:1430-4. 2005
    ..In conclusion, EDA could delay and ameliorate the urinary protein excretion in accordance with the urinary 8-OHdG excretion in PAN-induced nephrosis...
  33. ncbi request reprint Nephrotic syndrome associated with human parvovirus B19 infection
    Yoshiyuki Ohtomo
    Department of Pediatrics, Juntendo University, School of Medicine, Tokyo, Japan
    Pediatr Nephrol 18:280-2. 2003
    ..A renal biopsy showed mesangiocapillary proliferative glomerulonephritis with immune complex deposits associated with PVB19 virus. His renal involvement improved spontaneously...
  34. doi request reprint Increased nitric oxide production by T- and B-cells in idiopathic nephrotic syndrome
    Anna Iharada
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Nephrol 24:1033-8. 2009
    ..We conclude that an aberrant immune system may exist not only in T-cells but also in B-cells, and NO may play some role in INS...
  35. doi request reprint A child with Epstein-Barr Virus-associated hemophagocytic lymphohistiocytosis complicated by coronary artery lesion mimicking Kawasaki disease
    Shogo Kato
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    J Pediatr Hematol Oncol 35:e317-9. 2013
    ..We would like to draw attention that if features of KD become apparent in patients with HLH, echocardiographic examinations should be performed not to miss coronary artery lesion. ..
  36. pmc Postmortem computed tomography imaging in the investigation of nontraumatic death in infants and children
    Yukihiro Noda
    Department of Pediatrics, Kansai Medical University, 2 5 1 Shin machi, Hirakata shi, Osaka 573 1010, Japan
    Biomed Res Int 2013:327903. 2013
    ..To determine the accuracy of postmortem computed tomography (PMCT) for the assessment of causes in nontraumatic deaths in children...
  37. doi request reprint A case of WHIM syndrome associated with diabetes and hypothyroidism
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi, Osaka 570 8506, Japan
    Pediatr Diabetes 10:484-6. 2009
    ..Taken into consideration the concurrent prevalence of the two disorders and the speculated common pathogenesis associated with the CXCR4, our patient may enable us to understand the genetic damage related to accelerated apoptosis...
  38. ncbi request reprint Effects of human milk and spermine on hydrogen peroxide-induced oxidative damage in IEC-6 cells
    Hiromichi Shoji
    Department of Pediatrics, Juntendo University School of Medicine, Hongo, Tokyo, Japan
    J Pediatr Gastroenterol Nutr 41:460-5. 2005
    ..Human milk (HM) contains various bioactive substances, some of which are known as antioxidants, including polyamines such as spermine (SPM). We examined the antioxidative properties of HM and SPM in an intestinal epithelial cell line...
  39. ncbi request reprint Phagocytosis of heat-killed Staphylococcus aureus by eosinophils: comparison with neutrophils
    Yasuko Hatano
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    APMIS 117:115-23. 2009
    ..Whereas the mechanism of phagocytosis by neutrophils was mediated by CD16 and CD32, that of eosinophils was modulated by complement receptor 1 (CD35)...
  40. doi request reprint Two types of orthostatic dysregulation assessed by diameter of inferior vena cava
    Yuri Fujii
    Department of Pediatrics, Kansai Medical University Nakano Children s Hospital Osaka University of Comprehensive Children Education, Osaka, Japan
    Pediatr Int 53:162-7. 2011
    ..Orthostatic dysregulation (OD) is common in adolescents. This study was conducted to evaluate the usefulness of the measurement of the diameter of the inferior vena cava (IVC) for objective assessment of patients with OD...
  41. ncbi request reprint Low prevalence of hypercalciuria in Japanese children
    Kazunari Kaneko
    Department of Pediatrics, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Nephron 91:439-43. 2002
    ..We hypothesize that the low prevalence of urolithiasis is associated with the urinary calcium excretion. The aim of our study was to investigate the prevalence of hypercalciuria in Japanese children...
  42. pmc Small for gestational age and magnesium in cord blood platelets: intrauterine magnesium deficiency may induce metabolic syndrome in later life
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, 10 15 Fumizonocho, Moriguchi, Osaka 570 8506, Japan
    J Pregnancy 2011:270474. 2011
    ..In this review, we propose that intrauterine magnesium deficiency may induce metabolic syndrome in later life. We discuss the potential contribution of aberrant magnesium regulation to SGA and to the pathogenesis of metabolic syndrome...
  43. doi request reprint Methicillin-resistant Staphylococcus aureus-related glomerulonephritis in a child
    Takahisa Kimata
    Department of Pediatrics, Kansai Medical University, 2 3 1 Shin machi, Hirakata shi, Osaka 573 1191, Japan
    Pediatr Nephrol 27:2149-52. 2012
    ....
  44. ncbi request reprint Antibiotic prophylaxis by low-dose cefaclor in children with vesicoureteral reflux
    Kazunari Kaneko
    Department of Pediatrics, Juntendo University School of Medicine, 2 l l Hongo, Bunkyo ku, 113 8421, Tokyo, Japan
    Pediatr Nephrol 18:468-70. 2003
    ..None withdrew from the study because of side effects. These results suggest that cefaclor can be an alternative choice for prophylactic treatment because of its safety, good compliance and low rates of resistant Escherichia coli...
  45. doi request reprint Elevated intracellular calcium in neutrophils in patients with Down syndrome
    Fumiko Yamato
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Int 51:474-7. 2009
    ..The purpose of the present study was to compare the intracellular calcium concentration ([Ca(2+)]i) at baseline and stimulated conditions in DS patients and in normal subjects to investigate [Ca(2+)]i regulation in neutrophils...
  46. pmc Intracellular magnesium of obese and type 2 diabetes mellitus children
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, 10 15 Fumizonocho, Moriguchi, Osaka, 570 8506, Japan
    Diabetes Ther 1:25-31. 2010
    ..We studied the change of [Mg(2+)](i) in obese children and children with type 2 diabetes mellitus (DM2) after educational intervention or treatment...
  47. ncbi request reprint Intracellular magnesium and adipokines in umbilical cord plasma and infant birth size
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi, Osaka 570 8506, Japan
    Pediatr Res 62:700-3. 2007
    ..Mg]i and adiponectin were correlated with QUICKI in all subjects. [Mg]i, as well as leptin and IGF-I, reflect the extent of fetal growth. Decreased [Mg2+]i may be involved in the underlying processes to insulin resistance...
  48. ncbi request reprint [Electroencephalographic changes in sisters with infantile-onset dentatorubral-pallidoluysian atrophy (DRPLA)]
    Rika Hashi
    Department of Pediatrics, Otokoyama Hospital, Kansai Medical University, Yawata, Kyoto
    No To Hattatsu 39:445-9. 2007
    ..Myoclonic seizures developed at 4 years and 7 months, but have been well controlled using sodium valproate. EEG showed diffuse 3-4 Hz spike-and-wave complexes that were rather different from the findings in her elder sister...
  49. ncbi request reprint Magnesium deficiency in pregnant rats alters methylation of specific cytosines in the hepatic hydroxysteroid dehydrogenase-2 promoter of the offspring
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Epigenetics 6:573-8. 2011
    ..Therefore, a Mg-deficient diet alters glucocorticoid metabolism, predicting higher hepatic intracellular glucocorticoid concentrations, and is possibly a key mechanism that induces the metabolic complications of Mg deficiency...
  50. ncbi request reprint Cerebral edema in a child with diabetic ketoacidosis before initial treatment
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi, Japan
    Pediatr Int 49:395-6. 2007
  51. doi request reprint Cerebral blood flow monitoring using a novel laser Doppler flowmeter in asphyxiated infants
    Atsushi Ohashi
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Int 51:715-9. 2009
    ..The aim of the present study was to investigate the role of early changes in cerebral blood flow (CBF) predicting the severity of neurological outcome in asphyxiated infants...
  52. ncbi request reprint Simplified quantification of urinary protein excretion using a novel dipstick in children
    Kazunari Kaneko
    Department of Pediatrics, Juntendo University Urayasu Hospital, Chiba, Japan
    Pediatr Nephrol 20:834-6. 2005
    ..It is, therefore, a useful tool to monitor the urinary protein excretion in children with renal diseases at outpatient clinic...
  53. pmc A calcium-deficient diet in rat dams during gestation and nursing affects hepatic 11β-hydroxysteroid dehydrogenase-1 expression in the offspring
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi, Osaka, Japan
    PLoS ONE 9:e84125. 2014
    ..We hypothesized that pregnant female rats fed a Ca-deficient diet would have offspring with altered hepatic glucocorticoid-related gene expression and that lactation would modify these alterations...
  54. pmc A young child with pseudohypoaldosteronism type II by a mutation of Cullin 3
    Shoji Tsuji
    Department of Pediatrics, Kansai Medical University, 2 5 1 Shin machi, Hirakata shi, Osaka 573 1010, Japan
    BMC Nephrol 14:166. 2013
    ..Here, we firstly report on the Japanese child of PHA II caused by a mutation of CUL 3...
  55. ncbi request reprint Surgical repair of left ventricular noncompaction in a patient with a novel mutation of the myosin heavy chain 7 gene
    Takamichi Uchiyama
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Tohoku J Exp Med 228:301-4. 2012
    ..Although the postsurgical observational period was short, the findings indicate that LVNC mutation analyses may facilitate surgical decisions and help predict clinical courses...
  56. ncbi request reprint [Effective and efficient method of painless venepuncture in children]
    Naoyuki Kitamura
    Department of Pediatrics, Kansai Medical University, Hirakata
    Rinsho Byori 55:257-61. 2007
    ..To this end, several elements should be considered: preparation of procedural information, distraction during painful procedures, and local anesthesia. Current concepts to understand these elements are presented in this review...
  57. ncbi request reprint Cyclosporine A for heavy proteinuria in a child with Henoch-Schönlein purpura nephritis
    Tomonosuke Someya
    Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan
    Pediatr Int 46:111-3. 2004
  58. doi request reprint Effects of interview on mood status of pregnant women with high-risk delivery
    Naoyuki Kitamura
    Department of Pediatrics, Kansai Medical University, Osaka City University, Osaka, Japan
    Pediatr Int 51:498-501. 2009
    ..The purpose of the present study was to evaluate the effects of an interview by health professionals on their mood status...
  59. doi request reprint Management of intraventricular hemorrhage in preterm infants with low birth weight
    Takayuki Inagaki
    Department of Neurosurgery, Kansai Medical University, Osaka, Japan
    Acta Neurochir Suppl 113:173-5. 2012
    ..After evaluating our series, we modified our protocol from reservoir placement to either cerebrospinal fluid (CSF) drainage or ventriculosubgaleal shunt directly. We will reevaluate this new protocol in the near future...
  60. ncbi request reprint Factors related to patterns of body mass index in early infancy: 18 month longitudinal study
    Tohru Fujiwara
    Department of Pediatrics, Kansai Medical University, Osaka, Japan
    Pediatr Int 56:406-10. 2014
    ..The children with early AR, however, are not fully characterized. The aim of this study was to investigate the prevalence and characteristics of the infants who develop early AR...
  61. ncbi request reprint Usefulness of diffusion-weighted MRI in human herpesvirus-6 encephalitis
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi Shi, Osaka 570 8506, Japan
    Acta Paediatr 96:137-8. 2007
    ..Serial imaging showed that the diffusion abnormality DW-MRI returned to normal after 45 days...
  62. ncbi request reprint Usefulness of magnetic resonance cholangiopancreatography in biliary structures in infants: a four-case report
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, Moriguchi Shi, Osaka 570 8506, Japan
    Eur J Pediatr 166:211-4. 2007
    ..We conclude that MRCP can be used to depict the major biliary structures of neonates and small infants and to exclude BA as the cause of neonatal cholestasis by allowing visualisation of the biliary tract...
  63. doi request reprint Caspase inhibitor ZVAD-fmk facilitates engraftment of donor hematopoietic stem cells in intra-bone marrow-bone marrow transplantation
    Yuichiro Imai
    First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan
    Stem Cells Dev 19:461-8. 2010
    ..These results suggest that ZVAD-fmk can suppress apoptosis of hematopoietic stem cells and/or immature progenitor cells of the donor bone marrow cells, thereby accelerating the donor hematopoiesis...
  64. ncbi request reprint Pentalogy of Cantrell with a double-outlet right ventricle: 3.5-year follow-up in a prenatally diagnosed patient
    Junji Takaya
    Department of Pediatrics, Kansai Medical University, 10 15 Fumizonocho, Moriguchi, Osaka 570 8506, Japan
    Eur J Pediatr 167:103-5. 2008
    ..The patient is currently alive and well 3.5 years after surgery. It is concluded that a deliberate therapeutic strategy based on the intrauterine diagnosis may alter the natural history of this devastating disorder...
  65. ncbi request reprint Mechanisms underlying acceleration of blood flow recovery in ischemic limbs by macrophage colony-stimulating factor
    Keiji Nakano
    First Department of Pathology, Kansai Medical University, 10 15 Moriguchi, Osaka, Japan
    Stem Cells 24:1274-9. 2006
    ....
  66. ncbi request reprint [Fetus and magnesium]
    Junji Takaya
    Department of Pediatrics, Kansai Medical University
    Clin Calcium 15:105-10. 2005
    ..Prospective study whether the children born with magnesium induced IUGR are at high-risk for metabolic syndrome in childhood or adulthood is currently undertaken...
  67. ncbi request reprint Granulocyte-colony stimulating factor increases donor mesenchymal stem cells in bone marrow and their mobilization into peripheral circulation but does not repair dystrophic heart after bone marrow transplantation
    Kimiko Tatsumi
    The Department of Pediatrics, Kansai Medical University, Moriguchi, Japan
    Circ J 72:1351-8. 2008
    ..Hereditary disordered cardiac muscle could be replaced with intact cardiomyocytes derived from genetically intact bone marrow (BM)-derived stem cells...