A Takami

Summary

Affiliation: Kanazawa University
Country: Japan

Publications

  1. ncbi Expansion and activation of minor histocompatibility antigen HY-specific T cells associated with graft-versus-leukemia response
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    Bone Marrow Transplant 34:703-9. 2004
  2. doi A single-nucleotide polymorphism of the Fcγ receptor type IIIA gene in the recipient predicts transplant outcomes after HLA fully matched unrelated BMT for myeloid malignancies
    A Takami
    Department of Hematology and Oncology, Kanazawa University Hospital, Kanazawa, Japan
    Bone Marrow Transplant 46:238-43. 2011
  3. ncbi Immature platelet fraction for prediction of platelet engraftment after allogeneic stem cell transplantation
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
    Bone Marrow Transplant 39:501-7. 2007
  4. ncbi Reduced-intensity unrelated cord blood transplantation for treatment of metastatic renal cell carcinoma: first evidence of cord-blood-versus-solid-tumor effect
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Bone Marrow Transplant 38:729-32. 2006
  5. ncbi Isolated hyperkalemia associated with cyclosporine administration in allogeneic stem cell transplantation for renal cell carcinoma
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Int J Hematol 81:159-61. 2005
  6. ncbi Primary tracheal lymphoma: case report and literature review
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Japan
    Int J Hematol 82:338-42. 2005
  7. ncbi Safety and efficacy of foscarnet for preemptive therapy against cytomegalovirus reactivation after unrelated cord blood transplantation
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Transplant Proc 39:237-9. 2007
  8. ncbi Treatment of primary central nervous system lymphoma with induction of complement-dependent cytotoxicity by intraventricular administration of autologous-serum-supplemented rituximab
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa Univeristy Graduate School of Medicine, Kanazawa 920 8641, Japan
    Cancer Sci 97:80-3. 2006
  9. ncbi Menatetrenone, a vitamin K2 analog, ameliorates cytopenia in patients with refractory anemia of myelodysplastic syndrome
    A Takami
    Third Department of Medicine, Kanazawa University School of Medicine, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    Ann Hematol 81:16-9. 2002
  10. ncbi Mycophenolate mofetil is effective and well tolerated in the treatment of refractory acute and chronic graft-versus-host disease
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, University Graduate School of Medicine, Kanazawa, Japan
    Int J Hematol 83:80-5. 2006

Collaborators

Detail Information

Publications50

  1. ncbi Expansion and activation of minor histocompatibility antigen HY-specific T cells associated with graft-versus-leukemia response
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    Bone Marrow Transplant 34:703-9. 2004
    ....
  2. doi A single-nucleotide polymorphism of the Fcγ receptor type IIIA gene in the recipient predicts transplant outcomes after HLA fully matched unrelated BMT for myeloid malignancies
    A Takami
    Department of Hematology and Oncology, Kanazawa University Hospital, Kanazawa, Japan
    Bone Marrow Transplant 46:238-43. 2011
    ..22; 95% CI 0.06-0.77; P=0.02). The donor FCGR3A polymorphism did not have any effect on the transplant outcomes. These results suggest an association between the recipient FCGR3A genotype and the clinical outcomes after BMT...
  3. ncbi Immature platelet fraction for prediction of platelet engraftment after allogeneic stem cell transplantation
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
    Bone Marrow Transplant 39:501-7. 2007
    ..IPF counting may thus provide an accessible measure of thrombopoietic activity, leading to early evaluation of marrow function and allowing monitoring of platelet regeneration...
  4. ncbi Reduced-intensity unrelated cord blood transplantation for treatment of metastatic renal cell carcinoma: first evidence of cord-blood-versus-solid-tumor effect
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Bone Marrow Transplant 38:729-32. 2006
    ..The patient showed regression of metastatic disease, providing the first evidence of a graft-versus-tumor effect on a solid tumor resulting from cord blood graft...
  5. ncbi Isolated hyperkalemia associated with cyclosporine administration in allogeneic stem cell transplantation for renal cell carcinoma
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Int J Hematol 81:159-61. 2005
    ..We propose that the presence of a single functional kidney may be a risk factor for isolated hyperkalemia due to CSP...
  6. ncbi Primary tracheal lymphoma: case report and literature review
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Japan
    Int J Hematol 82:338-42. 2005
    ..Various histological subtypes of primary tracheal lymphoma exist and are likely to determine prognosis...
  7. ncbi Safety and efficacy of foscarnet for preemptive therapy against cytomegalovirus reactivation after unrelated cord blood transplantation
    A Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan
    Transplant Proc 39:237-9. 2007
    ..Foscarnet represents a safe and effective agent for preemptive therapy against CMV infection and may offer a feasible alternative to ganciclovir in UCBT recipients...
  8. ncbi Treatment of primary central nervous system lymphoma with induction of complement-dependent cytotoxicity by intraventricular administration of autologous-serum-supplemented rituximab
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa Univeristy Graduate School of Medicine, Kanazawa 920 8641, Japan
    Cancer Sci 97:80-3. 2006
    ....
  9. ncbi Menatetrenone, a vitamin K2 analog, ameliorates cytopenia in patients with refractory anemia of myelodysplastic syndrome
    A Takami
    Third Department of Medicine, Kanazawa University School of Medicine, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    Ann Hematol 81:16-9. 2002
    ..03). Significant improvement was also seen in final platelet count ( p=0.01), but not in hemoglobin concentration. Given the absence of toxicity, menatetrenone can be recommended for all patients with MDS-RA...
  10. ncbi Mycophenolate mofetil is effective and well tolerated in the treatment of refractory acute and chronic graft-versus-host disease
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, University Graduate School of Medicine, Kanazawa, Japan
    Int J Hematol 83:80-5. 2006
    ..This preliminary study suggests that MMF is a well-tolerated agent and has a beneficial effect in the treatment of refractory acute and chronic GVHD...
  11. ncbi Successful treatment of minimal residual disease-positive Philadelphia chromosome-positive acute lymphoblastic leukemia with imatinib followed by reduced-intensity unrelated cord blood transplantation after allogeneic peripheral blood stem cell transplant
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
    Int J Hematol 84:170-3. 2006
    ....
  12. doi Successful treatment of Trichosporon fungemia in a patient with refractory acute myeloid leukemia using voriconazole combined with liposomal amphotericin B
    K Hosokawa
    Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Transpl Infect Dis 14:184-7. 2012
    ..The combination therapy with voriconazole and L-AmB may therefore be useful in controlling Trichosporon fungemia associated with prolonged neutropenia after remission induction therapy for AML...
  13. doi A single nucleotide polymorphism of IL-17 gene in the recipient is associated with acute GVHD after HLA-matched unrelated BMT
    J L Espinoza
    Department of Hematology and Oncology, Kanazawa University Hospital, Kanazawa, Japan
    Bone Marrow Transplant 46:1455-63. 2011
    ..75-45.72; P=0.09), as well as a significantly increased risk for chronic GVHD (HR, 3.86; 95% CI, 1.29-11.59; P=0.02). These results suggest an association of the 197A genotype in the recipient side with the development of acute GVHD...
  14. doi Safety of pre-engraftment prophylactic foscarnet administration after allogeneic stem cell transplantation
    K Ishiyama
    Department of Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Transpl Infect Dis 14:33-9. 2012
    ..HHV-6 reactivation occurred in 3 of the 10 study subjects. The prophylactic PFA regimen was thus safe and it may reduce the risk of limbic encephalitis, but is not considered to be potent enough to prevent HHV-6 reactivation...
  15. ncbi Prospective phase II trial to evaluate the complications and kinetics of chimerism induction following allogeneic hematopoietic stem cell transplantation with fludarabine and busulfan
    Akiko M Saito
    Department of Hematology and Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Am J Hematol 82:873-80. 2007
    ..In older patients, RIST with fludarabine and busulfan was associated with acceptable toxicities and a satisfactory antileukemia effect, regardless of the early chimerism status...
  16. ncbi Early establishment of hematopoietic chimerism following allogeneic peripheral blood stem cell transplantation in comparison with allogeneic bone marrow transplantation
    S Nakao
    Third Department of Medicine, Kanazawa University School of Medicine, Isikawa, Japan
    Eur J Haematol 62:265-70. 1999
    ....
  17. doi Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with t(6;9)(p23;q34) dramatically improves the patient prognosis: a matched-pair analysis
    K Ishiyama
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan
    Leukemia 26:461-4. 2012
    ..A univariate analysis showed that t(6;9)(p23;q34) had no significant impact on the overall survival. These findings suggest that allogeneic HSCT may overcome the unfavorable impact of t(6;9)(p23;q34) as an independent prognostic factor...
  18. ncbi Elevated levels of free tissue factor pathway inhibitor antigen in cases of disseminated intravascular coagulation caused by various underlying diseases
    H Asakura
    Department of Internal Medicine III, Kanazawa University School of Medicine, Japan
    Blood Coagul Fibrinolysis 12:1-8. 2001
    ....
  19. ncbi Decreased plasma activity of antithrombin or protein C is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation
    H Asakura
    Department of Internal Medicine III, Kanazawa University School of Medicine, Kanazawa, Japan
    Eur J Haematol 67:170-5. 2001
    ..It is reasonable to conclude that the markedly reduced plasma activity of antithrombin and protein C is not due to consumption coagulopathy in septic patients with DIC...
  20. ncbi Peripheral neuropathy associated with chronic natural killer cell lymphocytosis
    Moeko Noguchi
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13 1 Takara machi, Kanazawa 920 8641, Japan
    J Neurol Sci 232:119-22. 2005
    ..Our observations suggest that the infiltrating NK cells may directly damage myelin and Schwann cells, thus causing demyelination...
  21. ncbi Immunoglobulin preparations attenuate organ dysfunction and hemostatic abnormality by suppressing the production of cytokines in lipopolysaccharide-induced disseminated intravascular coagulation in rats
    Hidesaku Asakura
    Department of Internal Medicine III, Kanazawa University School of Medicine, Ishikawa, Japan
    Crit Care Med 34:2421-5. 2006
    ..We attempted to clarify the effect of immunoglobulin concentrates on the rat lipopolysaccharide (LPS)-induced disseminated intravascular coagulation (DIC) model...
  22. ncbi Prospective trial of high-dose chemotherapy followed by infusions of peripheral blood stem cells and dose-escalated donor lymphocytes for relapsed leukemia after allogeneic stem cell transplantation
    Akiyoshi Takami
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
    Int J Hematol 82:449-55. 2005
    ..The low induction rate of GVHD and extramedullary relapse after remission is achieved with DLI are problems yet to be solved...
  23. ncbi Marked difference in pathophysiology between tissue factor- and lipopolysaccharide-induced disseminated intravascular coagulation models in rats
    Hidesaku Asakura
    Department of Internal Medicine III, Kanazawa University, School of Medicine, Ishikawa, Japan
    Crit Care Med 30:161-4. 2002
    ....
  24. ncbi Graft rejection and hyperacute graft-versus-host disease in stem cell transplantation from non-inherited maternal-antigen-complementary HLA-mismatched siblings
    Hirokazu Okumura
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
    Eur J Haematol 78:157-60. 2007
    ..The findings suggest that intensive conditioning and immunosuppression after stem cell transplantation are needed in NIMA-mismatched SCT even if donor and recipient microchimerisms is detectable in the donor and recipient before SCT...
  25. ncbi Antithrombotic role of nitric oxide in rats under physiological conditions
    Hidesaku Asakura
    Department of Internal Medicine III Kanazawa University School of Medicine Takaramachi 13 1, Kanazawa Ishikawa 920 8641, Japan
    Thromb Haemost 91:71-5. 2004
    ..These findings suggest that NO, in addition to regulating blood pressure, is involved in prevention of thrombus formation under physiological circumstances...
  26. doi Relationship between tumor-infiltrating T lymphocytes and clinical response after reduced-intensity allogeneic hematopoietic stem cell transplantation for advanced renal cell carcinoma: a single center prospective study
    Ken Ishiyama
    Division of Cancer Medicine, Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    Jpn J Clin Oncol 39:807-12. 2009
    ..We performed an institutional clinical study of HSCT for refractory RCC patients...
  27. doi Expansion of donor-derived hematopoietic stem cells with PIGA mutation associated with late graft failure after allogeneic stem cell transplantation
    Kanako Mochizuki
    Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Blood 112:2160-2. 2008
    ....
  28. ncbi Living-donor lobar lung transplantation for broncho-bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: does bronchiolitis obliterans recur in transplanted lungs?
    Hirokazu Okumura
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa 920 8641, Japan
    Int J Hematol 86:369-73. 2007
    ..LDLLT may therefore be considered a viable therapeutic option for the treatment of BO after allogeneic HSCT...
  29. ncbi Significance of decreased plasma D-dimer levels following lipopolysaccharide-induced disseminated intravascular coagulation in rats
    Hidesaku Asakura
    Department of Internal Medicine III, Kanazawa University School of Medicine, Kanazawa, Ishikawa, Japan
    Int J Hematol 79:394-9. 2004
    ..Thus care should be taken when evaluating the significance of plasma DD levels, because suppressed levels can occur with progressive fibrin deposition and worsening organ dysfunction or improvement in the course of DIC...
  30. ncbi Beneficial effect of low-molecular-weight heparin against lipopolysaccharide-induced disseminated intravascular coagulation in rats is abolished by coadministration of tranexamic acid
    Hidesaku Asakura
    Department of Internal Medicine III, Kanazawa University School of Medicine, Takaramachi 13 1, Kanazawa, Ishikawa 920 8641, Japan
    Intensive Care Med 30:1950-5. 2004
    ....
  31. doi CD16+ CD56- NK cells in the peripheral blood of cord blood transplant recipients: a unique subset of NK cells possibly associated with graft-versus-leukemia effect
    Xuzhang Lu
    Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    Eur J Haematol 81:18-25. 2008
    ....
  32. doi Mechanism of decrease of oral bioavailability of cyclosporin A during immunotherapy upon coadministration of amphotericin B
    Junko Ishizaki
    Department of Clinical Pharmaceutics, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Japan
    Biopharm Drug Dispos 29:195-203. 2008
    ..It is suggested that careful monitoring of CyA levels is necessary in the event of AMB administration to patients receiving immunotherapy with CyA...
  33. ncbi An idiopathic skin eruption resembling a butterfly rash in a septic patient with disseminated intravascular coagulation following bone marrow transplantation
    Yasuo Ontachi
    Department of Internal Medicine III, Kanazawa University School of Medicine, Takaramachi 13 1, Kanazawa 920 8641, Japan
    Blood Coagul Fibrinolysis 15:255-9. 2004
    ..But our patient developed this uncommon skin eruption on his face. Patients with an idiopathic skin eruption resembling a butterfly rash in a septic patient should be considered to complicate DIC as in the present case...
  34. ncbi A case of cardiac B cell lymphoma complicated by hemophagocytic syndrome
    Ontachi Yasuo
    Department of Internal Medicine III, Kanazawa University School of Medicine, Takaramachi 13 1, Kanazawa 920 8641, Japan
    Haematologica 87:ECR27. 2002
  35. ncbi Minor population of CD55-CD59- blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia
    Chiharu Sugimori
    Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8641, Japan
    Blood 107:1308-14. 2006
    ..Furthermore, immune attack against hematopoietic stem cells that allows PNH clonal expansion might occur only at the onset of AA...
  36. ncbi Roles of DRB1 *1501 and DRB1 *1502 in the pathogenesis of aplastic anemia
    Chiharu Sugimori
    Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    Exp Hematol 35:13-20. 2007
    ..We herein clarify the difference between DRB1( *)1501 and DRB1( *)1502, the two DRB1 alleles that determine the presentation of HLA-DR15, in the pathophysiology of AA...
  37. ncbi Macrophage colony-stimulating factor enhances rituximab-dependent cellular cytotoxicity by monocytes
    Shigeru Shimadoi
    Department of Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8641, Japan
    Cancer Sci 98:1368-72. 2007
    ..6- and 1.5-fold, whereas the expression of Fcgamma receptor II remained unchanged. These results suggest that pretreatment with M-CSF can improve the therapeutic efficacy of rituximab against intractable CD20(+) lymphoma...
  38. doi Cord blood transplantation using minimum conditioning regimens for patients with hematologic malignancies complicated by severe infections
    Takeshi Yamashita
    Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    Int J Hematol 89:238-42. 2009
    ....
  39. doi Origin and fate of blood cells deficient in glycosylphosphatidylinositol-anchored protein among patients with bone marrow failure
    Chiharu Sugimori
    Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan
    Br J Haematol 147:102-12. 2009
    ....
  40. ncbi Diazepam-binding inhibitor-related protein 1: a candidate autoantigen in acquired aplastic anemia patients harboring a minor population of paroxysmal nocturnal hemoglobinuria-type cells
    Xingmin Feng
    Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
    Blood 104:2425-31. 2004
    ..These findings indicate that DRS-1 may serve as an autoantigen eliciting immune attack against hematopoietic stem cells in a subset of AA patients characterized by increased PNH-type cells...
  41. ncbi Complete and durable remission of refractory mantle cell lymphoma with repeated rituximab monotherapy
    Ken Ishiyama
    Cellular Transplantation Biology, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa 920 8641, Japan
    Int J Hematol 81:319-22. 2005
    ..The pancytopenia gradually improved, and a complete remission was obtained after 4 cycles of rituximab. The patient remains in complete remission 21 months after the third rituximab therapy for maintenance...
  42. ncbi Graft-versus-leukemia effect of allogeneic stem cell transplantation; a Japanese single center study
    Ken Ishiyama
    Haematologica 89:887-9. 2004
    ..The cumulative incidence of relapse in patients with acute GVHD was significantly lower than that in patients without acute GVHD, but there was no similar GVL effect for chronic GVHD...
  43. ncbi Relapse of chronic myeloid leukemia (CML) in lymphoid crisis after allogeneic bone marrow transplantation for CML in chronic phase with busulfan plus cyclophosphamide regimen
    Akiyoshi Takami
    Haematologica 87:659-61. 2002
  44. ncbi [Cellular immunotherapy of hematologic malignancies attempted using minor histocompatibility antigens as targets]
    Akiyoshi Takami
    Rinsho Ketsueki 43:360-2. 2002
  45. ncbi Graft-versus-host disease following living donor liver transplantation
    Yuji Soejima
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Liver Transpl 10:460-4. 2004
    ..Therefore, it is possible that LDLT should be ruled out for such donors. A pretransplant work-up of the HLA type in both the donors and recipients is therefore imperative before determining the indications for LDLT...
  46. ncbi Reduced-intensity allogeneic stem cell transplantation for renal cell carcinoma: in vivo evidence of a graft-versus-tumor effect
    Akiyoshi Takami
    Haematologica 89:375-6. 2004
    ..In 2 partial responders, histologic analyses of metastases revealed prominent accumulation of CD8+ T cells and degenerative changes of clear cell carcinoma, suggestive of induction of tumor-specific cytotoxic T lymphocytes...
  47. ncbi [Non-myeloablative allogenic peripheral blood stem cell transplantation for treatment of advanced renal cell carcinoma]
    Hiroyuki Konaka
    The Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science
    Hinyokika Kiyo 51:503-7. 2005
    ....
  48. ncbi Chronic graft-versus-host disease following allogeneic peripheral blood and bone marrow stem cell transplants: a single center experience
    Akiyoshi Takami
    Haematologica 87:664-6. 2002
  49. ncbi [Reliability of low platelet counts--comparison of microscopic counts with automated hematology analyzer XE-2100]
    Michiko Orito
    Department of Clinical Laboratory, Kanazawa University Hospital, Kanazawa, 920 8641
    Rinsho Byori 53:793-801. 2005
    ..Thus, it was suggested that reliable platelet counts could be reported even in the samples with thrombocytopenia by switching system in XE-2100...
  50. ncbi High incidence of cytomegalovirus reactivation in adult recipients of an unrelated cord blood transplant
    Akiyoshi Takami
    Haematologica 90:1290-2. 2005
    ..These results suggest that unrelated cord blood transplantation itself may be correlated with a high incidence of CMV reactivation...