Masaki Shimizu

Summary

Affiliation: Kanazawa University
Country: Japan

Publications

  1. doi request reprint Tolvaptan therapy for massive edema in a patient with nephrotic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa, 920 8641, Japan
    Pediatr Nephrol 29:915-7. 2014
  2. doi request reprint Extensive serum biomarker analysis in patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan Electronic address
    Cytokine 66:1-6. 2014
  3. doi request reprint Distinct cytokine profile in juvenile systemic lupus erythematosus-associated macrophage activation syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Japan Electronic address
    Clin Immunol 146:73-6. 2013
  4. doi request reprint Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13 1 Takara machi, Kanazawa 920 8641, Japan
    Cytokine 61:345-8. 2013
  5. doi request reprint Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa 920 8641, Japan
    Cytokine 60:226-32. 2012
  6. pmc Sequentially appearing erythema nodosum, erythema multiforme and Henoch-Schönlein purpura in a patient with Mycoplasma pneumoniae infection: a case report
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa, 920 8641, Japan
    J Med Case Rep 6:398. 2012
  7. pmc Relapse of systemic juvenile idiopathic arthritis after influenza vaccination in a patient receiving tocilizumab
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Japan
    Clin Vaccine Immunol 19:1700-2. 2012
  8. ncbi request reprint Thomsen-Friedenreich antigen exposure as a cause of Streptococcus pyogenes-associated hemolytic-uremic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
    Clin Nephrol 78:328-31. 2012
  9. doi request reprint Cytokine profiles of patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan
    Cytokine 60:694-700. 2012
  10. doi request reprint Isolated congenital megacystis without intestinal obstruction: a mild variant of chronic intestinal pseudoobstruction syndrome?
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    J Pediatr Surg 46:e29-32. 2011

Collaborators

Detail Information

Publications28

  1. doi request reprint Tolvaptan therapy for massive edema in a patient with nephrotic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa, 920 8641, Japan
    Pediatr Nephrol 29:915-7. 2014
    ..The non-osmotic stimulation of arginine vasopressin release from the pituitary gland has been implicated as one of the important factors in abnormal water retention in patients with NS...
  2. doi request reprint Extensive serum biomarker analysis in patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan Electronic address
    Cytokine 66:1-6. 2014
    ..Furthermore, the levels of these cytokines were significantly increased in severe HUS compared with mild HUS. These cytokines might play an important role in the pathogenesis of HUS and may also be used to predict the severity of HUS. ..
  3. doi request reprint Distinct cytokine profile in juvenile systemic lupus erythematosus-associated macrophage activation syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Japan Electronic address
    Clin Immunol 146:73-6. 2013
    ..Furthermore, the cytokine profile of SLE-MAS differs from that of S-JIA-MAS: the TNF-α dominant increase appears to be characteristic...
  4. doi request reprint Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13 1 Takara machi, Kanazawa 920 8641, Japan
    Cytokine 61:345-8. 2013
    ..These two subsets appear to be characterized by certain distinct clinical features...
  5. doi request reprint Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa 920 8641, Japan
    Cytokine 60:226-32. 2012
    ..These findings suggest that the inactive phase of s-JIA represents a state of compensated inflammation rather than absence of immune activity...
  6. pmc Sequentially appearing erythema nodosum, erythema multiforme and Henoch-Schönlein purpura in a patient with Mycoplasma pneumoniae infection: a case report
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa, 920 8641, Japan
    J Med Case Rep 6:398. 2012
    ..abstract:..
  7. pmc Relapse of systemic juvenile idiopathic arthritis after influenza vaccination in a patient receiving tocilizumab
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Japan
    Clin Vaccine Immunol 19:1700-2. 2012
    ..Systemic symptoms of s-JIA might be masked during TCZ therapy. Careful observation with the monitoring of serum interleukin (IL)-18 and IL-6 levels may be useful...
  8. ncbi request reprint Thomsen-Friedenreich antigen exposure as a cause of Streptococcus pyogenes-associated hemolytic-uremic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
    Clin Nephrol 78:328-31. 2012
    ..Although the pathogenesis of GAS-associated HUS is not well understood, T-antigen exposure may be implicated in some cases with GAS-associated HUS...
  9. doi request reprint Cytokine profiles of patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan
    Cytokine 60:694-700. 2012
    ..Monitoring the cytokine profile may be useful for assessing disease activity of EHEC O111 infections...
  10. doi request reprint Isolated congenital megacystis without intestinal obstruction: a mild variant of chronic intestinal pseudoobstruction syndrome?
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    J Pediatr Surg 46:e29-32. 2011
    ..These findings indicate that this case may be a mild variant of chronic intestinal pseudoobstruction syndrome. The presence of megacystis should alert the physician to the possibility of chronic intestinal pseudoobstruction syndrome...
  11. doi request reprint Tocilizumab masks the clinical symptoms of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: the diagnostic significance of interleukin-18 and interleukin-6
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan
    Cytokine 58:287-94. 2012
    ....
  12. doi request reprint Successful treatment with bosentan for pulmonary hypertension and reduced peripheral circulation in juvenile systemic sclerosis
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
    Pediatr Cardiol 32:1040-2. 2011
    ..Prospective randomized trials are required to validate the effectiveness of bosentan for patients with juvenile SSc; however, bosentan might be useful for the management of patients with juvenile SSc...
  13. doi request reprint Urinary heme oxygenase-1 as a sensitive indicator of tubulointerstitial inflammatory damage in various renal diseases
    Tadafumi Yokoyama
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
    Am J Nephrol 33:414-20. 2011
    ..We examined urinary HO-1 (uHO-1) levels to assess whether uHO-1 acts as a sensitive biomarker for detecting tubulointerstitial inflammatory damage in renal diseases...
  14. ncbi request reprint Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells
    Masaki Shimizu
    Department of Pediatrics, Graduate School of Medical Science, Kanazawa University, Japan
    Pediatr Res 58:666-71. 2005
    ....
  15. doi request reprint Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa 920 8641, Japan
    Rheumatology (Oxford) 49:1645-53. 2010
    ....
  16. doi request reprint Accumulation of mature B cells in the inflamed muscle tissue of a patient with anti-155/140 antibody-positive juvenile dermatomyositis
    Tadafumi Yokoyama
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13 1 Takaramachi, Kanazawa, 920 8641, Japan
    Mod Rheumatol 23:167-71. 2013
    ..These findings indicate that loss of B cell tolerance and accumulation of mature B cells in inflamed muscle tissue play an important role in the pathogenesis of JDM...
  17. doi request reprint Flow cytometric analysis of skin blister fluid induced by mosquito bites in a patient with chronic active Epstein-Barr virus infection
    Taizo Wada
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, 920 8641, Japan
    Int J Hematol 90:611-5. 2009
    ..These results suggest that CD203c(+) cells as well as NK cells may play pathogenic roles in the severe skin reactions to mosquito bites in NK-CAEBV...
  18. ncbi request reprint Evaluation of T-Cell receptor diversity in pediatric patients with minimal change nephrotic syndrome
    Kazuhide Ohta
    Department of Pediatrics, Kanazawa Medical Center, National Hospital Organization, Kanazawa, Japan
    Clin Nephrol 77:296-304. 2012
    ....
  19. doi request reprint Soluble ST2 as a marker of disease activity in systemic juvenile idiopathic arthritis
    Sayaka Ishikawa
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan
    Cytokine 62:272-7. 2013
    ..These findings indicate that ST2 may be an important mediator in s-JIA. Serum sST2 levels in patients with s-JIA correlated with disease activity, suggesting a potential role as a promising indicator of disease activity...
  20. ncbi request reprint Rituximab therapy for Epstein-Barr virus-related chronic hepatitis following living donor kidney transplantation
    Kazuhide Ohta
    Department of Pediatrics, Graduate School of Medical Science, Kanazawa University, Ishikawa 920 8641, Japan
    Am J Kidney Dis 48:986-9. 2006
    ..The present case illustrates the significance of early diagnosis, monitoring of viral load, and vigorous management of EBV-related disorders associated with organ transplantation...
  21. doi request reprint Diffusion-weighted MRI of exercise-induced acute renal failure (ALPE)
    Kazuhide Ohta
    Department of Pediatrics, Kanazawa Medical Center, National Hospital Organization, 1 1 Shimo Ishibiki, Kanazawa, Ishikawa 920 8650, Japan
    Pediatr Nephrol 26:1321-4. 2011
    ..MRI is safer than contrast-enhanced CT for patients with ALPE. Diffusion-weighted MRI is a very useful examination for diagnosing ALPE, providing noninvasive detection of lesions peculiar to ALPE...
  22. ncbi request reprint [Case of systemic-onset juvenile idiopathic arthritis complicated with sepsis --usefulness of cytokine profile for the differentiation between macrophage activation syndrome and sepsis]
    Tadafumi Yokoyama
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
    Nihon Rinsho Meneki Gakkai Kaishi 34:105-11. 2011
    ..Therefore, our results suggest that a patient's cytokine profile may be a useful indicator of disease activity and may thus help in the differential diagnosis of sepsis and MAS in s-JIA...
  23. doi request reprint Detection of T lymphocytes with a second-site mutation in skin lesions of atypical X-linked severe combined immunodeficiency mimicking Omenn syndrome
    Taizo Wada
    Department of Pediatrics, Graduate School of Medical Science, Kanazawa University, Japan
    Blood 112:1872-5. 2008
    ..These findings suggest that the clinical spectrum of XSCID is quite broad and includes atypical cases mimicking Omenn syndrome, and highlight the importance of revertant mosaicism as a possible cause for variable phenotypic expression...
  24. pmc Successful treatment of primary sclerosing cholangitis with a steroid and a probiotic
    Masaki Shimizu
    Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
    Case Rep Gastroenterol 6:249-53. 2012
    ..Suppression of bowel inflammation and maintenance of bacterial homeostasis may be important for treating PSC...
  25. ncbi request reprint Evolution of acute focal bacterial nephritis into a renal abscess
    Masaki Shimizu
    Department of Pediatrics, Fukuiken Saiseikai Hospital, 7 1 Wadanakacho Funabashi, Fukui 918 8503, Fukui City, Japan
    Pediatr Nephrol 20:93-5. 2005
    ..It is important to differentiate AFBN from renal abscess because the management of the two entities may be different, and follow-up studies are indispensable to determine appropriate therapy...
  26. ncbi request reprint Selective protection of renal tubular epithelial cells by heme oxygenase (HO)-1 during stress-induced injury
    Yonghong Yang
    Department of Pediatrics, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan
    Kidney Int 64:1302-9. 2003
    ..These facts suggest that the renal tubuli are dependent on intrinsic HO-1 production for their survival under oxidative stresses...
  27. ncbi request reprint Cytomegalovirus-associated protracted diarrhoea in an immunocompetent boy
    Masaki Shimizu
    Department of Pediatrics, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan
    J Paediatr Child Health 42:259-62. 2006
    ..We describe here an immunocompetent 1-year-old boy with CMV-associated protracted diarrhoea and discuss the pathogenesis of CMV infection of the gastrointestinal tract...
  28. doi request reprint Allogeneic bone marrow transplantation appears to ameliorate IgA nephropathy in a patient with X-linked thrombocytopenia
    Akihiro Hoshino
    Department of Pediatrics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930 0194, Japan
    J Clin Immunol 34:53-7. 2014
    ..The amount of galactose-deficient IgA in the patient's serum markedly decreased after BMT. Therefore, immunological reconstitution might improve autoimmune diseases in patients with WAS/XLT. ..