T Sasagawa

Summary

Affiliation: Kanazawa University
Country: Japan

Publications

  1. ncbi Immunoglobulin-A and -G responses against virus-like particles (VLP) of human papillomavirus type 16 in women with cervical cancer and cervical intra-epithelial lesions
    T Sasagawa
    Department of Obstetrics and Gynecology, Kanazawa University, School of Medicine, Ishikawa, Japan
    Int J Cancer 75:529-35. 1998
  2. ncbi A human papillomavirus type 16 vaccine by oral delivery of L1 protein
    Toshiyuki Sasagawa
    Health Science, School of Medicine, Kanazawa University, 5 11 80 Kodatsuno, Kanazawa, Ishikawa 920 0942, Japan
    Virus Res 110:81-90. 2005
  3. ncbi Overexpression of latent transforming growth factor-beta 1 (TGF-beta 1) binding protein 1 (LTBP-1) in association with TGF-beta 1 in ovarian carcinoma
    T Higashi
    Department of Hygiene, Kanazawa University School of Medicine, Kanazawa 920 8640, Japan
    Jpn J Cancer Res 92:506-15. 2001
  4. ncbi High-risk and multiple human papillomavirus infections associated with cervical abnormalities in Japanese women
    T Sasagawa
    School of Health Sciences, Faculty of Medicine, Kanazawa University, Ishikawa, Japan
    Cancer Epidemiol Biomarkers Prev 10:45-52. 2001
  5. ncbi A new PCR-based assay amplifies the E6-E7 genes of most mucosal human papillomaviruses (HPV)
    T Sasagawa
    School of Health Sciences, Kanazawa University, Ishikawa, Japan
    Virus Res 67:127-39. 2000
  6. ncbi The evaluation of human papillomavirus DNA testing in primary screening for cervical lesions in a large Japanese population
    M Inoue
    Department of Obstetrics and Gynecology, School of Medicine, Kanazawa University, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8640, Japan
    Int J Gynecol Cancer 16:1007-13. 2006
  7. ncbi Hybrid capture-II and LCR-E7 PCR assays for HPV typing in cervical cytologic samples
    H Yamazaki
    Department of Obstetrics and Gynecology, Turuga Municipal Hospital, Turuga, Japan
    Int J Cancer 94:222-7. 2001
  8. ncbi Alteration of beta-catenin expression in esophageal squamous-cell carcinoma
    I Ninomiya
    Department of Surgery II, School of Medicine, Kanazawa University, Kanazawa, Japan
    Int J Cancer 85:757-61. 2000
  9. ncbi Clinicopathological significance of fragile histidine triad transcription protein expression in endometrial carcinomas
    T Segawa
    Department of Obstetrics and Gynecology, School of Medicine, Kanazawa University, Japan
    Clin Cancer Res 6:2341-8. 2000
  10. ncbi Reduction in the local expression of complement component 6 (C6) and 7 (C7) mRNAs in oesophageal carcinoma
    R Oka
    Department of Hygiene, Kanazawa University School of Medicine, 13 1 Takara machi, 920 8640, Kanazawa, Japan
    Eur J Cancer 37:1158-65. 2001

Collaborators

Detail Information

Publications13

  1. ncbi Immunoglobulin-A and -G responses against virus-like particles (VLP) of human papillomavirus type 16 in women with cervical cancer and cervical intra-epithelial lesions
    T Sasagawa
    Department of Obstetrics and Gynecology, Kanazawa University, School of Medicine, Ishikawa, Japan
    Int J Cancer 75:529-35. 1998
    ..This serological assay using HPV-16 VLP may therefore be useful as a new diagnostic tool supplementing cervical cytological tests...
  2. ncbi A human papillomavirus type 16 vaccine by oral delivery of L1 protein
    Toshiyuki Sasagawa
    Health Science, School of Medicine, Kanazawa University, 5 11 80 Kodatsuno, Kanazawa, Ishikawa 920 0942, Japan
    Virus Res 110:81-90. 2005
    ..This freeze-dried yeast system may be useful as an oral delivery of HPV 16 L1 protein...
  3. ncbi Overexpression of latent transforming growth factor-beta 1 (TGF-beta 1) binding protein 1 (LTBP-1) in association with TGF-beta 1 in ovarian carcinoma
    T Higashi
    Department of Hygiene, Kanazawa University School of Medicine, Kanazawa 920 8640, Japan
    Jpn J Cancer Res 92:506-15. 2001
    ..Taken together, the results suggest that upregulation of LTBP-1 in ovarian carcinoma cells may have an important role in distributing TGF-beta1 in the stromal tissues surrounding carcinoma cells...
  4. ncbi High-risk and multiple human papillomavirus infections associated with cervical abnormalities in Japanese women
    T Sasagawa
    School of Health Sciences, Faculty of Medicine, Kanazawa University, Ishikawa, Japan
    Cancer Epidemiol Biomarkers Prev 10:45-52. 2001
    ..HPV typing and detection of multiple HPV infections in clinical samples may be useful as surrogate markers for cervical cell abnormalities...
  5. ncbi A new PCR-based assay amplifies the E6-E7 genes of most mucosal human papillomaviruses (HPV)
    T Sasagawa
    School of Health Sciences, Kanazawa University, Ishikawa, Japan
    Virus Res 67:127-39. 2000
    ..LCR-E7 PCR may be useful for determining the biological activity of detected HPV types, since this method amplifies the entire E6 gene...
  6. ncbi The evaluation of human papillomavirus DNA testing in primary screening for cervical lesions in a large Japanese population
    M Inoue
    Department of Obstetrics and Gynecology, School of Medicine, Kanazawa University, 13 1 Takaramachi, Kanazawa, Ishikawa 920 8640, Japan
    Int J Gynecol Cancer 16:1007-13. 2006
    ..However, most importantly, HPV DNA testing in combination with cytology significantly improved the efficacy to CIN screening...
  7. ncbi Hybrid capture-II and LCR-E7 PCR assays for HPV typing in cervical cytologic samples
    H Yamazaki
    Department of Obstetrics and Gynecology, Turuga Municipal Hospital, Turuga, Japan
    Int J Cancer 94:222-7. 2001
    ..Thus, we propose that both HCA-II and LCR-E7 PCR are valuable screening tests for premalignant and malignant cervical lesions...
  8. ncbi Alteration of beta-catenin expression in esophageal squamous-cell carcinoma
    I Ninomiya
    Department of Surgery II, School of Medicine, Kanazawa University, Kanazawa, Japan
    Int J Cancer 85:757-61. 2000
    ..Furthermore, it is suggested that beta-catenin over-expression is not caused by genetic alteration of either the beta-catenin or the APC gene...
  9. ncbi Clinicopathological significance of fragile histidine triad transcription protein expression in endometrial carcinomas
    T Segawa
    Department of Obstetrics and Gynecology, School of Medicine, Kanazawa University, Japan
    Clin Cancer Res 6:2341-8. 2000
    ....
  10. ncbi Reduction in the local expression of complement component 6 (C6) and 7 (C7) mRNAs in oesophageal carcinoma
    R Oka
    Department of Hygiene, Kanazawa University School of Medicine, 13 1 Takara machi, 920 8640, Kanazawa, Japan
    Eur J Cancer 37:1158-65. 2001
    ..Our findings suggest a possible relationship between oesophageal tumorigenesis and reduced expression of C6 and C7 mRNAs, which is probably caused by a change in gene expression regulation and not by genetic loss of the locus...
  11. ncbi Characterization of adriamycin-induced G2 arrest and its abrogation by caffeine in FL-amnion cells with or without p53
    Y Minemoto
    Department of Life Science, Graduate School of Natural Science and Technology, Kanazawa University, Japan
    Exp Cell Res 262:37-48. 2001
    ..These results suggest that p53 and p21 do not have special roles in the S- and G2-phase checkpoints and that CDK2:cyclin A could be the target of the G2-phase DNA damage checkpoint...
  12. ncbi Enhanced immunogenicity of human papillomavirus 16 L1 genetic vaccines fused to an ER-targeting secretory signal peptide and RANTES
    S J Kim
    Comprehensive Gynecologic Cancer Center, Pundang CHA General Hospital, Sungnam, Kyonggi-do, South Korea
    Gene Ther 10:1268-73. 2003
    ..These results suggest that the immunogenicity of HPV L1 DNA vaccines could be enhanced by genetic fusion to a chemokine and secretory signal peptide sequences...
  13. ncbi Sexual behaviour and high risk human papillomavirus infections in Japanese women
    T Sasagawa
    Sex Transm Infect 81:280-2. 2005