Koichiro Sakai

Summary

Affiliation: Kanazawa Medical University
Country: Japan

Publications

  1. ncbi request reprint Binding of the ELAV-like protein in murine autoimmune T-cells to the nonameric AU-rich element in the 3' untranslated region of CD154 mRNA
    Koichiro Sakai
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa 920 0293
    Mol Immunol 39:879-83. 2003
  2. ncbi request reprint Primary skeletal muscle involvement in chorea-acanthocytosis
    Shinji Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa 920 0293, Japan
    Mov Disord 22:848-52. 2007
  3. ncbi request reprint Induction of humoral responses specific for paraneoplastic cerebellar degeneration-associated antigen by whole recombinant yeast immunization
    Misuzu Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa 920 02, Japan
    J Autoimmun 24:203-8. 2005
  4. ncbi request reprint Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity
    Koichiro Sakai
    Department of Neurology, Kanazawa Medical University, Kahoku gun, 920 0293 Ishikawa, Japan
    Neurobiol Dis 15:529-33. 2004
  5. ncbi request reprint Neurological deficits are associated with increased brain calcinosis, hypoperfusion, and hypometabolism in idiopathic basal ganglia calcification
    Misuzu Saiki
    Department of Neurology, Kanazawa Medical University, Ishikawa, Japan
    Mov Disord 22:1027-30. 2007
  6. ncbi request reprint Chorea-acanthocytosis associated with Tourettism
    Shinji Saiki
    Department of Neurology, Kanazawa Medical University, Ishikawa, Japan
    Mov Disord 19:833-6. 2004
  7. ncbi request reprint Cardiac 123I-MIBG scintigraphy can assess the disease severity and phenotype of PD
    Shinji Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa 920 0923, Japan
    J Neurol Sci 220:105-11. 2004
  8. ncbi request reprint Ictal alteration of 99mTc ECD SPECT imaging in a patient with secondary paroxysmal kinesigenic dyskinesia caused by hyperglycemia
    Misuzu Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa 920 0293, Japan
    Rinsho Shinkeigaku 45:312-6. 2005
  9. ncbi request reprint Valproic acid-induced hearing loss and tinnitus
    Ariyuki Hori
    Department of Neurology, Kanazawa Medical University, Uchinada, Ishikawa
    Intern Med 42:1153-4. 2003
  10. ncbi request reprint [Stiff-person syndrome]
    Koichiro Sakai
    Department of Neurology, Kanazawa Medical University
    Nihon Rinsho 60:838-41. 2002

Collaborators

  • S Saiki
  • Ichiro Matsunari
  • Makoto Matsui
  • Koichi Tomoda
  • Susumu Fujino
  • N Hattori
  • T Ichiyama
  • Misuzu Saiki
  • Genjiro Hirose
  • Ken Ya Murata
  • Ryo Hirai
  • Aya Nakajima
  • Jun Konishi
  • Kazuo Nagashima
  • Ariyuki Hori
  • Akiko Shiratsuchi
  • Toshiko Nagashima
  • Kotaro Higashi
  • Yoko Kitagawa
  • Motohiro Yukitake
  • Yasuo Sugita
  • Mitsuyoshi Ayabe
  • Yuichiro Gondo
  • Masahide Kaji
  • Yasuo Kuroda
  • Yoko Inoue
  • Haruo Mizuta
  • Hiroshi Shoji
  • Megumi Nakanishi
  • Kazuhiro Kurohara
  • Akiko Nagaishi
  • Ichiro Kinoshita
  • Hirotoshi Dosaka-Akita
  • Masaharu Nishimura
  • Koichi Yamazaki
  • Kanako Chikai
  • Masakatsu Motomura
  • Toshiya Shinohara
  • Yoshinobu Nakanishi
  • Yasuko Orba
  • Yoshihiko Terayama
  • Satoshi Kataoka
  • Hirofumi Sawa
  • Yasuyuki Mizutani
  • Tomoe Mori
  • Yae Takahashi
  • Noriko Iwasaki
  • Shiro Maguchi
  • Masayuki Takashima
  • Takayo Chuma
  • Tomoo Itoh
  • Hiromasa Kawahara
  • Akiko Horiguchi
  • Yukio Mano

Detail Information

Publications17

  1. ncbi request reprint Binding of the ELAV-like protein in murine autoimmune T-cells to the nonameric AU-rich element in the 3' untranslated region of CD154 mRNA
    Koichiro Sakai
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa 920 0293
    Mol Immunol 39:879-83. 2003
    ..Modification of the expression of CD154 on autoimmune T-cells by regulating the ELAV-like protein may provide effective therapy for EAE and human multiple sclerosis...
  2. ncbi request reprint Primary skeletal muscle involvement in chorea-acanthocytosis
    Shinji Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa 920 0293, Japan
    Mov Disord 22:848-52. 2007
    ..This histological observation suggests chorein abnormalities of skeletal muscles might be associated with primary involvement of skeletal muscles in this disorder...
  3. ncbi request reprint Induction of humoral responses specific for paraneoplastic cerebellar degeneration-associated antigen by whole recombinant yeast immunization
    Misuzu Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada machi, Kahoku gun, Ishikawa 920 02, Japan
    J Autoimmun 24:203-8. 2005
    ..The immunization technique based on the recombinant yeast expressing a PCD-associated antigen provides a new tool for analyzing the underlying immunological pathomechanisms of PCD...
  4. ncbi request reprint Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity
    Koichiro Sakai
    Department of Neurology, Kanazawa Medical University, Kahoku gun, 920 0293 Ishikawa, Japan
    Neurobiol Dis 15:529-33. 2004
    ..Because derepression of the B-myb promoter has been implicated in neuronal death, the results suggest the possible role of the antibodies in the pathogenesis of PCD...
  5. ncbi request reprint Neurological deficits are associated with increased brain calcinosis, hypoperfusion, and hypometabolism in idiopathic basal ganglia calcification
    Misuzu Saiki
    Department of Neurology, Kanazawa Medical University, Ishikawa, Japan
    Mov Disord 22:1027-30. 2007
    ..These findings suggest that an interruption of neuronal circuitry may cause neurological deficits. The degree of neurological deficits may correlate with the severity of calcinosis and the reduction of perfusion and metabolism...
  6. ncbi request reprint Chorea-acanthocytosis associated with Tourettism
    Shinji Saiki
    Department of Neurology, Kanazawa Medical University, Ishikawa, Japan
    Mov Disord 19:833-6. 2004
    ..The [(18)F]-2-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) findings did not explain the differences in symptomatology between the patient and his sister, although they may have correlated with severity...
  7. ncbi request reprint Cardiac 123I-MIBG scintigraphy can assess the disease severity and phenotype of PD
    Shinji Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa 920 0923, Japan
    J Neurol Sci 220:105-11. 2004
    ..Whether this decrease is associated with clinical severity as assessed by the Unified Parkinson's Disease Rating Scale (UPDRS) and the phenotypes of PD has not been determined...
  8. ncbi request reprint Ictal alteration of 99mTc ECD SPECT imaging in a patient with secondary paroxysmal kinesigenic dyskinesia caused by hyperglycemia
    Misuzu Saiki
    Department of Neurology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa 920 0293, Japan
    Rinsho Shinkeigaku 45:312-6. 2005
    ..These findings suggest that dysfunction of the indirect pathway through the basal ganglia lead to an imbalance of the cortico-striato-thalamo-cortical circuit and may have contributed to the cause of PKD in this case...
  9. ncbi request reprint Valproic acid-induced hearing loss and tinnitus
    Ariyuki Hori
    Department of Neurology, Kanazawa Medical University, Uchinada, Ishikawa
    Intern Med 42:1153-4. 2003
  10. ncbi request reprint [Stiff-person syndrome]
    Koichiro Sakai
    Department of Neurology, Kanazawa Medical University
    Nihon Rinsho 60:838-41. 2002
  11. ncbi request reprint Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X
    Koichiro Sakai
    The Department of Neurology, Kanazawa Medical University, Kahoku gun, Ishikawa, Japan
    Mol Cell Neurosci 19:477-84. 2002
    ..MRG X, which is thought to be functionally related to the cell cycle and cell growth, may be regulated by PCD17/cdr2 in Purkinje cells...
  12. ncbi request reprint Huntington's disease-like 2 can present as chorea-acanthocytosis
    Shinji Saiki
    Neurology 63:939-40; author reply 939-40. 2004
  13. ncbi request reprint A presumed human nuclear autoantigen that translocates to plasma membrane blebs during apoptosis
    Akiko Shiratsuchi
    Graduate School of Medical Science and Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa, Ishikawa 920 0934, Japan
    J Biochem 133:211-8. 2003
    ..These results suggest that cleavage-dependent exit from the nucleus during apoptosis is a phenomenon common to nuclear autoantigens...
  14. ncbi request reprint Paraneoplastic cerebellar degeneration (PCD) associated with squamous cell carcinoma of the lung
    Jun Konishi
    First Department of Medicine, Hokkaido University School of Medicine, Sapporo
    Intern Med 43:602-6. 2004
    ..These findings are compatible with paraneoplastic cerebellar degeneration (PCD). To our knowledge, no case of PCD has been reported previously in patients with squamous cell carcinoma of the lung...
  15. ncbi request reprint Herpes simplex encephalitis presenting with bilateral hippocampal lesions on magnetic resonance imaging, simultaneously complicated by small cell lung carcinoma
    Ryo Hirai
    First Department Neurology of Internal Medicine, Kurume University School of Medicine, Japan
    Intern Med 44:1006-8. 2005
    ..Our findings suggest that HSE and paraneoplastic limbic encephalitis (PLE) can overlap, and we discuss the relationships of HSE, PLE, and related disorders...
  16. ncbi request reprint Anti-Hu paraneoplastic syndrome presenting with brainstem-cerebellar symptoms and Lambert-Eaton myasthenic syndrome
    Toshiko Nagashima
    Seiwa Memorial Hospital, Sapporo, Japan
    Neuropathology 23:230-8. 2003
    ....
  17. ncbi request reprint [An autopsied case of limbic encephalitis associated with extremely high titers of anti-SS-A antibodies in serum and anti-neuronal antibodies in CSF]
    Aya Nakajima
    Division of Neurology, Department of Medicine, Saga University Faculty of Medicine
    Rinsho Shinkeigaku 45:100-4. 2005
    ..Those immunological and pathological findings thus suggest an antibody-mediated autoimmune limbic encephalitis in our case...